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The map label for this gene is fhuA [H]

Identifier: 116694731

GI number: 116694731

Start: 886900

End: 889083

Strand: Direct

Name: fhuA [H]

Synonym: H16_B0785

Alternate gene names: 116694731

Gene position: 886900-889083 (Clockwise)

Preceding gene: 116694728

Following gene: 116694732

Centisome position: 30.45

GC content: 69.09

Gene sequence:

>2184_bases
ATGCTGCTTGCGCAGCTCAGCCGTGCCCGGCGCCGCGCGCCGTTTTCGTTCCAGCCTGTTGTGCCAGACCTGCGCCCGGT
CCAGGCGCGTTCATTGCGGCCGGTTGCCGCCCTGATGCTGGCGATGTCCGGCCTGGCCGAGGCGGCGGATACCACCGAGG
CCTCCGATATTACGCTGCCGGCGGTGTCGGTGGTCGGCACGGCCTCCGCATCATACAACCCGCCCGACGCCTCCGGCGCG
ACCCGCACCGACACGCCGCTGCGCGAAATTCCACAGTCGGTGCGCGTGGTGCCGCGCGCCATGCTGGACGATATCGCCGC
GACCCGTTTCGCCCAGACCTTCGACTATGTCAGCGGCATCGCGCGCCAGAACAACTTCGGCGGCCTGTGGGACAACTTCG
CCATGCGCGGCTTCACCGGCCATGAGAACACCGGCGCGGGCTACCTGGTCAACGGCTTTGCCGCCAACCGCGGCTATACC
GCGCCGATGGATGCGGCCACGATCGAACGCGTGGAAGTGCTCAAGGGCCCGACGTCATCGCTGTACGGCACCAGCGAGCC
GGGCGGCACCTTCAACGTGGTCACGCGCCAGCCGCAGTTCCGGCCTGCGCAGCGCTATGGCTTCGAGCTTGGCACGCGCG
ACGGCTATCGTGCCACGGCCGATGTCACCGGCCCGCTTGGCGAGAACGTGGCCGGCCGGCTGATCGCCGTGGCCGACCAC
CAGGGCAGCACGCGCGACTACATCAACAGCCAGCGCTACCTGGTGGCGCCGTCGTTCACCTGGACCCTGGGCAACGACAC
CGTGCTGCAGTACGCGGCCGAATTCCAGCGCTACACCACGCCGATGGACCGCGGCGTGGTGGCCGTCAACGGCCAGCTGG
GCCGCATCCCGCGCTCGCGCTTCCTGGGCGAGCCCGGCGACGGCGACATGCGGCTGGACAGCCAGTCGCACCAGCTCAGC
GTGGAGCACCAGTTCAGTCAGAACTGGAAGGGCAGGCTCGGCCTGTCCTACCGCGGCGGCGCACTGACGGGACATAGCAG
CGAGGCGACTTCACTGGCCGCCGACGGCCGCACGCTCTGGCGCCAGCGCCGCTACCGTGACTTCCAGTCGGACGATGTCT
CGCTGCAGGCCAGCGTGACCGGCAAGTTCAGCACCGGCCCGGTCGGGCATGAACTGCTGATGGGGGTGGATGCCTACCGC
TTCGGCAATACCATGGCGATCCTGCGCAAGAACCCCAGCGCCGCGGCGCCGTACGCGATCGACATCTACGACCCGGCCTA
TGGCCAGCCGGCGCCGCCGATGCCGTGGAACATGGACACGTACGAGCGCCAGCGCAATCTCGGCGCCTACGCGCAGGACC
AGCTGAGCCTGGGCGAGCGCTGGCGCGTGCTGGCCGGCGTGCGCTTCGACGCCTTCGACCAGTCGCTGGACAACCACCTG
CGCGGCACGCGCACCACGCAGCACCAGAACGCAGTGTCGCCGCGCGTGGGCGTGAGCTACCTGGCCAGCCAGAACGTGTC
GCTGTTTGCCAATGCCAGCCAGTCATTCCGTCCCAATGCCGGCGCCGACGCCGCGGGGCTGCCGTTCGACCCCGAGCGCG
GCCGCGCGGTGGAGGCCGGCATCAAGTTCGACAGCGAGGACCGCCGCAGCGGCGCCACGCTGGCCATCTTTGAGATCCGC
AAGCGCAATGTGCTGGCCACCGACCCGTCCGATCCCTCCTTCTATATCGCCGCCGGCGAAGCGCGCAGCCGCGGCCTGGA
GCTGGATGTGGCCGGGCAGCTTGGCACCCACTGGCGCGTATCGGGCAGTTTTGCGCTGACCGATGCCGAGATCACGCAGG
ACACGCGCCTGGCCGCCGGCACGCCGCTGTCCAACGTGCCGCGCACCAGCGGCAGCGTGCTGGCGGTGTACGAGGATGCC
GCGCCGGTGGGCCAGCGCTATGGCGTTGGTGCCGGCCTGCGTTATGTGGGGCGGCGTCCGGGCGATGTGCAGGACAGCTT
CTCGCTGCCGGCCTATGTGCTGGTGGACCTGCATGGCTACTGGCAATACAGCCGCAACGTGCGCGTGTCGCTCAACGTGG
GCAACCTGTTCGACAAGACCTATTACGCCAGTTCGTACAGCAGCCTGTGGATTGCGCCGGGCGCGGGCCGCAGTGTGCGG
CTGGGCGTGCAACTGAGCTATTGA

Upstream 100 bases:

>100_bases
TGACTAGAATCTTAATGAGAAATTATTATCATTAGTGAGTCGCTGCGGTTTGCCAGTCGGATGGCCGCCGCCGCGACTCG
TTTTTATTGGGGTGTTCCTT

Downstream 100 bases:

>100_bases
CGATGCTGCCAGCCAAGGCGCGCACTGCCGCGCCCCTGTCTTCTCCGACAGATTTCCCTTCTGCCGCGGTCGCGCGGCCG
GCCGGCGGCCGGCTGCTGTC

Product: outer membrane receptor, TonB-dependent

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 727; Mature: 727

Protein sequence:

>727_residues
MLLAQLSRARRRAPFSFQPVVPDLRPVQARSLRPVAALMLAMSGLAEAADTTEASDITLPAVSVVGTASASYNPPDASGA
TRTDTPLREIPQSVRVVPRAMLDDIAATRFAQTFDYVSGIARQNNFGGLWDNFAMRGFTGHENTGAGYLVNGFAANRGYT
APMDAATIERVEVLKGPTSSLYGTSEPGGTFNVVTRQPQFRPAQRYGFELGTRDGYRATADVTGPLGENVAGRLIAVADH
QGSTRDYINSQRYLVAPSFTWTLGNDTVLQYAAEFQRYTTPMDRGVVAVNGQLGRIPRSRFLGEPGDGDMRLDSQSHQLS
VEHQFSQNWKGRLGLSYRGGALTGHSSEATSLAADGRTLWRQRRYRDFQSDDVSLQASVTGKFSTGPVGHELLMGVDAYR
FGNTMAILRKNPSAAAPYAIDIYDPAYGQPAPPMPWNMDTYERQRNLGAYAQDQLSLGERWRVLAGVRFDAFDQSLDNHL
RGTRTTQHQNAVSPRVGVSYLASQNVSLFANASQSFRPNAGADAAGLPFDPERGRAVEAGIKFDSEDRRSGATLAIFEIR
KRNVLATDPSDPSFYIAAGEARSRGLELDVAGQLGTHWRVSGSFALTDAEITQDTRLAAGTPLSNVPRTSGSVLAVYEDA
APVGQRYGVGAGLRYVGRRPGDVQDSFSLPAYVLVDLHGYWQYSRNVRVSLNVGNLFDKTYYASSYSSLWIAPGAGRSVR
LGVQLSY

Sequences:

>Translated_727_residues
MLLAQLSRARRRAPFSFQPVVPDLRPVQARSLRPVAALMLAMSGLAEAADTTEASDITLPAVSVVGTASASYNPPDASGA
TRTDTPLREIPQSVRVVPRAMLDDIAATRFAQTFDYVSGIARQNNFGGLWDNFAMRGFTGHENTGAGYLVNGFAANRGYT
APMDAATIERVEVLKGPTSSLYGTSEPGGTFNVVTRQPQFRPAQRYGFELGTRDGYRATADVTGPLGENVAGRLIAVADH
QGSTRDYINSQRYLVAPSFTWTLGNDTVLQYAAEFQRYTTPMDRGVVAVNGQLGRIPRSRFLGEPGDGDMRLDSQSHQLS
VEHQFSQNWKGRLGLSYRGGALTGHSSEATSLAADGRTLWRQRRYRDFQSDDVSLQASVTGKFSTGPVGHELLMGVDAYR
FGNTMAILRKNPSAAAPYAIDIYDPAYGQPAPPMPWNMDTYERQRNLGAYAQDQLSLGERWRVLAGVRFDAFDQSLDNHL
RGTRTTQHQNAVSPRVGVSYLASQNVSLFANASQSFRPNAGADAAGLPFDPERGRAVEAGIKFDSEDRRSGATLAIFEIR
KRNVLATDPSDPSFYIAAGEARSRGLELDVAGQLGTHWRVSGSFALTDAEITQDTRLAAGTPLSNVPRTSGSVLAVYEDA
APVGQRYGVGAGLRYVGRRPGDVQDSFSLPAYVLVDLHGYWQYSRNVRVSLNVGNLFDKTYYASSYSSLWIAPGAGRSVR
LGVQLSY
>Mature_727_residues
MLLAQLSRARRRAPFSFQPVVPDLRPVQARSLRPVAALMLAMSGLAEAADTTEASDITLPAVSVVGTASASYNPPDASGA
TRTDTPLREIPQSVRVVPRAMLDDIAATRFAQTFDYVSGIARQNNFGGLWDNFAMRGFTGHENTGAGYLVNGFAANRGYT
APMDAATIERVEVLKGPTSSLYGTSEPGGTFNVVTRQPQFRPAQRYGFELGTRDGYRATADVTGPLGENVAGRLIAVADH
QGSTRDYINSQRYLVAPSFTWTLGNDTVLQYAAEFQRYTTPMDRGVVAVNGQLGRIPRSRFLGEPGDGDMRLDSQSHQLS
VEHQFSQNWKGRLGLSYRGGALTGHSSEATSLAADGRTLWRQRRYRDFQSDDVSLQASVTGKFSTGPVGHELLMGVDAYR
FGNTMAILRKNPSAAAPYAIDIYDPAYGQPAPPMPWNMDTYERQRNLGAYAQDQLSLGERWRVLAGVRFDAFDQSLDNHL
RGTRTTQHQNAVSPRVGVSYLASQNVSLFANASQSFRPNAGADAAGLPFDPERGRAVEAGIKFDSEDRRSGATLAIFEIR
KRNVLATDPSDPSFYIAAGEARSRGLELDVAGQLGTHWRVSGSFALTDAEITQDTRLAAGTPLSNVPRTSGSVLAVYEDA
APVGQRYGVGAGLRYVGRRPGDVQDSFSLPAYVLVDLHGYWQYSRNVRVSLNVGNLFDKTYYASSYSSLWIAPGAGRSVR
LGVQLSY

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=742, Percent_Identity=28.167115902965, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1787024, Length=778, Percent_Identity=24.5501285347044, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1787344, Length=741, Percent_Identity=24.1565452091768, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1790743, Length=558, Percent_Identity=22.2222222222222, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79014; Mature: 79014

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAQLSRARRRAPFSFQPVVPDLRPVQARSLRPVAALMLAMSGLAEAADTTEASDITLP
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEC
AVSVVGTASASYNPPDASGATRTDTPLREIPQSVRVVPRAMLDDIAATRFAQTFDYVSGI
CEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQNNFGGLWDNFAMRGFTGHENTGAGYLVNGFAANRGYTAPMDAATIERVEVLKGPTSS
HHCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHH
LYGTSEPGGTFNVVTRQPQFRPAQRYGFELGTRDGYRATADVTGPLGENVAGRLIAVADH
CCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECC
QGSTRDYINSQRYLVAPSFTWTLGNDTVLQYAAEFQRYTTPMDRGVVAVNGQLGRIPRSR
CCCCHHHHCCCEEEEECCEEEECCCHHHHHHHHHHHHHCCCHHCCEEEECCCCCCCCHHH
FLGEPGDGDMRLDSQSHQLSVEHQFSQNWKGRLGLSYRGGALTGHSSEATSLAADGRTLW
HCCCCCCCCEEECCCCCEEEEEEHHCCCCCCEEEEEECCCEECCCCCCCHHHHCCCHHHH
RQRRYRDFQSDDVSLQASVTGKFSTGPVGHELLMGVDAYRFGNTMAILRKNPSAAAPYAI
HHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCHHHHCCCEEEEEECCCCCCCCEEE
DIYDPAYGQPAPPMPWNMDTYERQRNLGAYAQDQLSLGERWRVLAGVRFDAFDQSLDNHL
EECCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
RGTRTTQHQNAVSPRVGVSYLASQNVSLFANASQSFRPNAGADAAGLPFDPERGRAVEAG
CCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
IKFDSEDRRSGATLAIFEIRKRNVLATDPSDPSFYIAAGEARSRGLELDVAGQLGTHWRV
CEECCCCCCCCCEEEEEEEECCCEEEECCCCCCEEEEECCHHHCCEEEEECCCCCCEEEE
SGSFALTDAEITQDTRLAAGTPLSNVPRTSGSVLAVYEDAAPVGQRYGVGAGLRYVGRRP
CCCEEEECCHHCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCHHHHCCCC
GDVQDSFSLPAYVLVDLHGYWQYSRNVRVSLNVGNLFDKTYYASSYSSLWIAPGAGRSVR
CCCCCCCCCCEEEEEEEECCEEECCCEEEEEECCCHHHHHEECCCCCEEEEECCCCCEEE
LGVQLSY
EEEEECC
>Mature Secondary Structure
MLLAQLSRARRRAPFSFQPVVPDLRPVQARSLRPVAALMLAMSGLAEAADTTEASDITLP
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEC
AVSVVGTASASYNPPDASGATRTDTPLREIPQSVRVVPRAMLDDIAATRFAQTFDYVSGI
CEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQNNFGGLWDNFAMRGFTGHENTGAGYLVNGFAANRGYTAPMDAATIERVEVLKGPTSS
HHCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHH
LYGTSEPGGTFNVVTRQPQFRPAQRYGFELGTRDGYRATADVTGPLGENVAGRLIAVADH
CCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECC
QGSTRDYINSQRYLVAPSFTWTLGNDTVLQYAAEFQRYTTPMDRGVVAVNGQLGRIPRSR
CCCCHHHHCCCEEEEECCEEEECCCHHHHHHHHHHHHHCCCHHCCEEEECCCCCCCCHHH
FLGEPGDGDMRLDSQSHQLSVEHQFSQNWKGRLGLSYRGGALTGHSSEATSLAADGRTLW
HCCCCCCCCEEECCCCCEEEEEEHHCCCCCCEEEEEECCCEECCCCCCCHHHHCCCHHHH
RQRRYRDFQSDDVSLQASVTGKFSTGPVGHELLMGVDAYRFGNTMAILRKNPSAAAPYAI
HHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCHHHHCCCEEEEEECCCCCCCCEEE
DIYDPAYGQPAPPMPWNMDTYERQRNLGAYAQDQLSLGERWRVLAGVRFDAFDQSLDNHL
EECCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
RGTRTTQHQNAVSPRVGVSYLASQNVSLFANASQSFRPNAGADAAGLPFDPERGRAVEAG
CCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
IKFDSEDRRSGATLAIFEIRKRNVLATDPSDPSFYIAAGEARSRGLELDVAGQLGTHWRV
CEECCCCCCCCCEEEEEEEECCCEEEECCCCCCEEEEECCHHHCCEEEEECCCCCCEEEE
SGSFALTDAEITQDTRLAAGTPLSNVPRTSGSVLAVYEDAAPVGQRYGVGAGLRYVGRRP
CCCEEEECCHHCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCHHHHCCCC
GDVQDSFSLPAYVLVDLHGYWQYSRNVRVSLNVGNLFDKTYYASSYSSLWIAPGAGRSVR
CCCCCCCCCCEEEEEEEECCEEECCCEEEEEECCCHHHHHEECCCCCEEEEECCCCCEEE
LGVQLSY
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]