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The map label for this gene is hcrC [H]

Identifier: 116694696

GI number: 116694696

Start: 840915

End: 841391

Strand: Direct

Name: hcrC [H]

Synonym: H16_B0745

Alternate gene names: 116694696

Gene position: 840915-841391 (Clockwise)

Preceding gene: 116694695

Following gene: 116694697

Centisome position: 28.87

GC content: 66.25

Gene sequence:

>477_bases
ATGAACCAAGTCAGCATCGAACTCACCGTCAACGGCGAGGAACACCAGGTGGAGGTGCCGGCGCGGCGCCTGCTGTCCGA
CCTGCTGCGCGACGACCTGAACCTGACCGGCACCAAGCGTGGCTGCGAGACCGGCATCTGCGGCGCCTGCTCCGTGCTGG
TCGACGGCGAGGTGGTCAAGTCCTGCCTGATGCTCGCCGTGCAGGCGCGCGGGCGCCATGTGATGACGGTGGAGGGGCTG
GCCGCCGACGGCCAGCTGCATCCGCTGCAGCAGTGCTTCATGGACAACGGCGGGCTGCAGTGCGGCTATTGCACGCCGGG
CTTCCTGATGGCCTCGTGCGCGCTGCTTGCCAATAACCCCAACCCGACCGAAGACGAAGTCCGGCACGGCCTGAACGGCA
ACCTGTGCCGCTGCACCGGCTATGTCGGCATCGTTGAATCGGTCCTGTCCGCCGCGGAGAAAATGCGTGGAAATTGA

Upstream 100 bases:

>100_bases
CATGCGCGGGTCCGAAAGCTACCGGCGCGAGATGGTGCGGGTAGTCGCGCGCCGCACCATTGCCGAGCTGTTCGGCGTGG
CATCGGAGTAAGGAATCCCC

Downstream 100 bases:

>100_bases
AAAGACCCTGGTCACCGCGGCGCCGCCGGCGCGCGTGTGGGAGCTGCTGCTCGACCCCAACGTGATGGGCGCGTGCGTGC
CCGGCATGGAATCGATCGAA

Product: 4-hydroxybenzoyl-CoA reductase 2Fe-2S iron-sulfur cluster subunit C

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MNQVSIELTVNGEEHQVEVPARRLLSDLLRDDLNLTGTKRGCETGICGACSVLVDGEVVKSCLMLAVQARGRHVMTVEGL
AADGQLHPLQQCFMDNGGLQCGYCTPGFLMASCALLANNPNPTEDEVRHGLNGNLCRCTGYVGIVESVLSAAEKMRGN

Sequences:

>Translated_158_residues
MNQVSIELTVNGEEHQVEVPARRLLSDLLRDDLNLTGTKRGCETGICGACSVLVDGEVVKSCLMLAVQARGRHVMTVEGL
AADGQLHPLQQCFMDNGGLQCGYCTPGFLMASCALLANNPNPTEDEVRHGLNGNLCRCTGYVGIVESVLSAAEKMRGN
>Mature_158_residues
MNQVSIELTVNGEEHQVEVPARRLLSDLLRDDLNLTGTKRGCETGICGACSVLVDGEVVKSCLMLAVQARGRHVMTVEGL
AADGQLHPLQQCFMDNGGLQCGYCTPGFLMASCALLANNPNPTEDEVRHGLNGNLCRCTGYVGIVESVLSAAEKMRGN

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=88, Percent_Identity=43.1818181818182, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI91823271, Length=138, Percent_Identity=40.5797101449275, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=40.4761904761905, Blast_Score=135, Evalue=9e-34,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=48.6486486486487, Blast_Score=133, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=47.4025974025974, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17539860, Length=161, Percent_Identity=37.888198757764, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=168, Percent_Identity=36.3095238095238, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17737937, Length=133, Percent_Identity=41.3533834586466, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=36.0759493670886, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647199, Length=158, Percent_Identity=34.8101265822785, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=35.3658536585366, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=35.3658536585366, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=36.875, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16863; Mature: 16863

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
6.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQVSIELTVNGEEHQVEVPARRLLSDLLRDDLNLTGTKRGCETGICGACSVLVDGEVVK
CCEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHEECHHHHH
SCLMLAVQARGRHVMTVEGLAADGQLHPLQQCFMDNGGLQCGYCTPGFLMASCALLANNP
HHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHCCCCCEECCCCHHHHHHHHHHHCCCC
NPTEDEVRHGLNGNLCRCTGYVGIVESVLSAAEKMRGN
CCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQVSIELTVNGEEHQVEVPARRLLSDLLRDDLNLTGTKRGCETGICGACSVLVDGEVVK
CCEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHEECHHHHH
SCLMLAVQARGRHVMTVEGLAADGQLHPLQQCFMDNGGLQCGYCTPGFLMASCALLANNP
HHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHCCCCCEECCCCHHHHHHHHHHHCCCC
NPTEDEVRHGLNGNLCRCTGYVGIVESVLSAAEKMRGN
CCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]