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The map label for this gene is yfcG [H]

Identifier: 116694522

GI number: 116694522

Start: 643188

End: 643892

Strand: Direct

Name: yfcG [H]

Synonym: H16_B0571

Alternate gene names: 116694522

Gene position: 643188-643892 (Clockwise)

Preceding gene: 116694521

Following gene: 116694523

Centisome position: 22.08

GC content: 65.53

Gene sequence:

>705_bases
GTGCCCGATCTGTCCGCTTTCCCCATCACCCGCAAATGGCCGGCGCAGCATCCCGACCGCATCCAGCTGTATTCCCTGCC
CACGCCCAACGGGGTCAAGGTGTCGATCATGCTGGAGGAGACCGGCCTGCCGTATGAACCGCACCTGGTGCGCTTCGACG
CCAACGACCAGATGTCGCCGGAGTTCCTGTCGCTGAGCCCGAACAACAAGATTCCCGCCATCCTCGATCCCAACGGTCCG
GGCGGCAAGCCGCTGGCGCTGTTCGAATCGGGCGCGATCCTGCTCTACCTGGCCGACAAGTCGGGCCAGCTGATCCCGGC
CGACCCCGCGCGCCGCTACGAAACCATCCAGTGGGTGATGTTCCAGATGGGCGGCATCGGGCCGATGTTCGGGCAGGTGG
GCTTTTTCCACAAGTTCGCGGGCAAGGAGTACGAGGACAAGCGCCCGCGCGACCGCTACGTGGCCGAAAGCCGGCGCCTG
CTGAATGTGCTGAACCAGCGGCTGGAAGGGCGCGACTGGATCATGGGCGACACCTACACCATTGCCGATATCGCCACCTT
CCCGTGGGTGCGCAACCTGCTTGGCTTCTATGAGGCGGGCGAACTGGTCGGCATCCAGGACTTCCCGCATGTCAGGCGCG
TGCTGGAGGCCTTCGTGAAGCGCCCGGCGGTGGTGAAGGGGCTCGATACGCCGCACCGCGGCTGA

Upstream 100 bases:

>100_bases
GCCCTGCGCTGCATGCATGGCAGGAGCGGTTTATGATCGGGCTTTTCCGTTGTCCGGCGCCTTCTTGCGCAGTGCGCAAG
CGCCTGAACCAGGAGCCAGT

Downstream 100 bases:

>100_bases
GGCAGCCTGCGGCGTGCGCGCCGCGGGCGTGGGCATCGTCCTACACGGCGGCCTCCCCGGCGCCTACAGAGGGGCGGGCG
GCACGCATCCTATAGTCCAG

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MPDLSAFPITRKWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHLVRFDANDQMSPEFLSLSPNNKIPAILDPNGP
GGKPLALFESGAILLYLADKSGQLIPADPARRYETIQWVMFQMGGIGPMFGQVGFFHKFAGKEYEDKRPRDRYVAESRRL
LNVLNQRLEGRDWIMGDTYTIADIATFPWVRNLLGFYEAGELVGIQDFPHVRRVLEAFVKRPAVVKGLDTPHRG

Sequences:

>Translated_234_residues
MPDLSAFPITRKWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHLVRFDANDQMSPEFLSLSPNNKIPAILDPNGP
GGKPLALFESGAILLYLADKSGQLIPADPARRYETIQWVMFQMGGIGPMFGQVGFFHKFAGKEYEDKRPRDRYVAESRRL
LNVLNQRLEGRDWIMGDTYTIADIATFPWVRNLLGFYEAGELVGIQDFPHVRRVLEAFVKRPAVVKGLDTPHRG
>Mature_233_residues
PDLSAFPITRKWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHLVRFDANDQMSPEFLSLSPNNKIPAILDPNGPG
GKPLALFESGAILLYLADKSGQLIPADPARRYETIQWVMFQMGGIGPMFGQVGFFHKFAGKEYEDKRPRDRYVAESRRLL
NVLNQRLEGRDWIMGDTYTIADIATFPWVRNLLGFYEAGELVGIQDFPHVRRVLEAFVKRPAVVKGLDTPHRG

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=43.5406698564593, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI87082195, Length=221, Percent_Identity=41.1764705882353, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87081789, Length=208, Percent_Identity=29.3269230769231, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324100, Length=262, Percent_Identity=30.5343511450382, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17933730, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI85725204, Length=170, Percent_Identity=32.3529411764706, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17737923, Length=170, Percent_Identity=32.3529411764706, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571670, Length=177, Percent_Identity=29.9435028248588, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864592, Length=218, Percent_Identity=28.4403669724771, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45549270, Length=179, Percent_Identity=30.7262569832402, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17864594, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26461; Mature: 26330

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLSAFPITRKWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHLVRFDANDQMSP
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCC
EFLSLSPNNKIPAILDPNGPGGKPLALFESGAILLYLADKSGQLIPADPARRYETIQWVM
CEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCCEECCCHHHHHHHHHHHH
FQMGGIGPMFGQVGFFHKFAGKEYEDKRPRDRYVAESRRLLNVLNQRLEGRDWIMGDTYT
HHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEE
IADIATFPWVRNLLGFYEAGELVGIQDFPHVRRVLEAFVKRPAVVKGLDTPHRG
HHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCC
>Mature Secondary Structure 
PDLSAFPITRKWPAQHPDRIQLYSLPTPNGVKVSIMLEETGLPYEPHLVRFDANDQMSP
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCC
EFLSLSPNNKIPAILDPNGPGGKPLALFESGAILLYLADKSGQLIPADPARRYETIQWVM
CEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCCEECCCHHHHHHHHHHHH
FQMGGIGPMFGQVGFFHKFAGKEYEDKRPRDRYVAESRRLLNVLNQRLEGRDWIMGDTYT
HHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEE
IADIATFPWVRNLLGFYEAGELVGIQDFPHVRRVLEAFVKRPAVVKGLDTPHRG
HHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]