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The map label for this gene is rtcB [H]

Identifier: 116694506

GI number: 116694506

Start: 625460

End: 626689

Strand: Direct

Name: rtcB [H]

Synonym: H16_B0555

Alternate gene names: 116694506

Gene position: 625460-626689 (Clockwise)

Preceding gene: 116694505

Following gene: 116694510

Centisome position: 21.48

GC content: 68.21

Gene sequence:

>1230_bases
ATGACGGACAAGCGCCACTATGACGTGCTGGACACCGGCGCCGGCAAGCCGGTCAAGCTGTGGACGCGCGGCGTCCCGGT
GGAAGGCGCTGCCCGCGAGCAACTGCTGAACACGGCGCGGATGCCGTTCATCTTCCGCCATGTTGCGGTGATGCCGGATG
TACATCTGGGCAAGGGCTCGACCATCGGCTCGGTGATCCCGACCGTGGGCGCGGTGATTCCCGCCGCGGTGGGCGTGGAT
ATCGGCTGCGGCATGATGGCCGTGAAGACCTCGCTCACCGCCGCTGACCTGCCCGACAACCTCGGGCCGCTGCGCAGCGC
GATCGAGCACGCCGTTCCTCACGGTCGCACCGCGCAGGGCGGGCGGCGCGACCAGGGGGCCTGGGGCTCGGCGCCGGCGC
CCGTTGACGCGGCATGGGCCGAAATGGCGCCGGGCTTTCGCCGCATCACCGACAAGTATCCGCACCTGGCGCGCACCAAC
CATCGCAATCACCTGGGCACGCTCGGCACCGGCAACCACTTTATCGAGGTGTGCCTGGACGAGGCCCAGTCAGTCTGGTT
CATGCTGCACAGCGGCTCGCGCGGCGTCGGCAATGCCATCGGCACGACCTTCATTTCGCTGGCGCAGCAGGACATGCGCA
AGCACCTCGCCAACCTGCCGGACCGCGACCTGGCCTACCTGGTCGAAGGCTCCACGCACTACGAGGACTACATCTTCGCC
GTGTCATGGGCCCAGGCCTACGCGCGCCGCAACCGCGAGCTGATGATGGAGGCGGTGCTGGCCGCTGCGCAGCGCGTGCT
GCGCAAGCCCTTCCAGGCGCAGCTGGAGGCGGTCAACTGCCACCACAACTACGTGCAGAAGGAGCATCACTTCGGCGCCG
ACGTGCTGGTAACGCGCAAGGGCGCGGTCAGTGCGCGCGTGGGCGAGCTGGGCATCATCCCGGGATCGATGGGCGCGCGC
TCGTTCATCGTGCGCGGCAAGGGCAACCCGGAATCGTTCTGCTCATGCAGCCACGGCGCGGGGCGCACCATGAGCCGCAG
CGAGGCCAAGCGCCGTTTCACCGTGGCCGACCAGGTGCATGCGACCGAGGGGGTCGAATGCCGCAAGGACGCCGCGGTGA
TCGACGAGATCCCGATGGCGTACAAGGACATCGACGCGGTGATGGCGGCGCAGGCTGACCTGGTGGAGATCGTGCACACG
TTGCGGCAGGTGGTGTGCGTGAAAGGCTGA

Upstream 100 bases:

>100_bases
CTTCGGCAGCTTCCTGCTGGGCTGAGTCGGGCGGCAGGGAATCCTGGACTGGCCCTGGCCGTCTAACCTGCAATCCGCGA
CGACAAAGCCAGGGGCGGCC

Downstream 100 bases:

>100_bases
ACGGCGGTTGCCCTCGCCGCCGAGCGGCCTCTGGCAGGGGCATCCGGCACTGAATCCGCCCTGCGCAGAGGCATTGCAGC
CGGGGCCACTCTACTGGAAG

Product: RtcB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTDKRHYDVLDTGAGKPVKLWTRGVPVEGAAREQLLNTARMPFIFRHVAVMPDVHLGKGSTIGSVIPTVGAVIPAAVGVD
IGCGMMAVKTSLTAADLPDNLGPLRSAIEHAVPHGRTAQGGRRDQGAWGSAPAPVDAAWAEMAPGFRRITDKYPHLARTN
HRNHLGTLGTGNHFIEVCLDEAQSVWFMLHSGSRGVGNAIGTTFISLAQQDMRKHLANLPDRDLAYLVEGSTHYEDYIFA
VSWAQAYARRNRELMMEAVLAAAQRVLRKPFQAQLEAVNCHHNYVQKEHHFGADVLVTRKGAVSARVGELGIIPGSMGAR
SFIVRGKGNPESFCSCSHGAGRTMSRSEAKRRFTVADQVHATEGVECRKDAAVIDEIPMAYKDIDAVMAAQADLVEIVHT
LRQVVCVKG

Sequences:

>Translated_409_residues
MTDKRHYDVLDTGAGKPVKLWTRGVPVEGAAREQLLNTARMPFIFRHVAVMPDVHLGKGSTIGSVIPTVGAVIPAAVGVD
IGCGMMAVKTSLTAADLPDNLGPLRSAIEHAVPHGRTAQGGRRDQGAWGSAPAPVDAAWAEMAPGFRRITDKYPHLARTN
HRNHLGTLGTGNHFIEVCLDEAQSVWFMLHSGSRGVGNAIGTTFISLAQQDMRKHLANLPDRDLAYLVEGSTHYEDYIFA
VSWAQAYARRNRELMMEAVLAAAQRVLRKPFQAQLEAVNCHHNYVQKEHHFGADVLVTRKGAVSARVGELGIIPGSMGAR
SFIVRGKGNPESFCSCSHGAGRTMSRSEAKRRFTVADQVHATEGVECRKDAAVIDEIPMAYKDIDAVMAAQADLVEIVHT
LRQVVCVKG
>Mature_408_residues
TDKRHYDVLDTGAGKPVKLWTRGVPVEGAAREQLLNTARMPFIFRHVAVMPDVHLGKGSTIGSVIPTVGAVIPAAVGVDI
GCGMMAVKTSLTAADLPDNLGPLRSAIEHAVPHGRTAQGGRRDQGAWGSAPAPVDAAWAEMAPGFRRITDKYPHLARTNH
RNHLGTLGTGNHFIEVCLDEAQSVWFMLHSGSRGVGNAIGTTFISLAQQDMRKHLANLPDRDLAYLVEGSTHYEDYIFAV
SWAQAYARRNRELMMEAVLAAAQRVLRKPFQAQLEAVNCHHNYVQKEHHFGADVLVTRKGAVSARVGELGIIPGSMGARS
FIVRGKGNPESFCSCSHGAGRTMSRSEAKRRFTVADQVHATEGVECRKDAAVIDEIPMAYKDIDAVMAAQADLVEIVHTL
RQVVCVKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=441, Percent_Identity=27.891156462585, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI2367224, Length=408, Percent_Identity=67.156862745098, Blast_Score=593, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI17506665, Length=449, Percent_Identity=25.3897550111359, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24585217, Length=443, Percent_Identity=26.410835214447, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 44332; Mature: 44201

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRHYDVLDTGAGKPVKLWTRGVPVEGAAREQLLNTARMPFIFRHVAVMPDVHLGKGS
CCCCCCCCHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
TIGSVIPTVGAVIPAAVGVDIGCGMMAVKTSLTAADLPDNLGPLRSAIEHAVPHGRTAQG
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCCHHHHHHHHHHHCCCCCCCCC
GRRDQGAWGSAPAPVDAAWAEMAPGFRRITDKYPHLARTNHRNHLGTLGTGNHFIEVCLD
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
EAQSVWFMLHSGSRGVGNAIGTTFISLAQQDMRKHLANLPDRDLAYLVEGSTHYEDYIFA
HHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHH
VSWAQAYARRNRELMMEAVLAAAQRVLRKPFQAQLEAVNCHHNYVQKEHHFGADVLVTRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GAVSARVGELGIIPGSMGARSFIVRGKGNPESFCSCSHGAGRTMSRSEAKRRFTVADQVH
CCCCEECCCEECCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ATEGVECRKDAAVIDEIPMAYKDIDAVMAAQADLVEIVHTLRQVVCVKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDKRHYDVLDTGAGKPVKLWTRGVPVEGAAREQLLNTARMPFIFRHVAVMPDVHLGKGS
CCCCCCCHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
TIGSVIPTVGAVIPAAVGVDIGCGMMAVKTSLTAADLPDNLGPLRSAIEHAVPHGRTAQG
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCCHHHHHHHHHHHCCCCCCCCC
GRRDQGAWGSAPAPVDAAWAEMAPGFRRITDKYPHLARTNHRNHLGTLGTGNHFIEVCLD
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
EAQSVWFMLHSGSRGVGNAIGTTFISLAQQDMRKHLANLPDRDLAYLVEGSTHYEDYIFA
HHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHH
VSWAQAYARRNRELMMEAVLAAAQRVLRKPFQAQLEAVNCHHNYVQKEHHFGADVLVTRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GAVSARVGELGIIPGSMGARSFIVRGKGNPESFCSCSHGAGRTMSRSEAKRRFTVADQVH
CCCCEECCCEECCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ATEGVECRKDAAVIDEIPMAYKDIDAVMAAQADLVEIVHTLRQVVCVKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9738023 [H]