Click here to switch to the map view.

The map label for this gene is yfiQ [C]

Identifier: 116694339

GI number: 116694339

Start: 437842

End: 439986

Strand: Direct

Name: yfiQ [C]

Synonym: H16_B0386

Alternate gene names: 116694339

Gene position: 437842-439986 (Clockwise)

Preceding gene: 116694338

Following gene: 116694345

Centisome position: 15.03

GC content: 70.12

Gene sequence:

>2145_bases
ATGTCGACACGCGATCTCTATACCCACGCGCAACTGCGGCGCCTCTTCCATCCGCGCACCATCGCGGTGGTCGGCGCGAC
GCCGAACGCTCGCTCGTTCGCCGGCCGGGCCATGACGAACCTGCAGCAGTTCGACGGCAACGTGCTGCTGGTCAACCCCC
GCTACCCCGAGGTGAACGGGCAGGTCTGCTATCCGTCGCTGTCGGCGCTGCCCGAGGCGCCCGACTGCGTGCTGATCGCC
ACCGCGCGCGAAACGGTGGAGCCCATCGTGCGCGAGTGCGCGGGGCTGGGCGTGGGCGGCGTGGTGCTGTTCGCGTCGGG
CTATGCCGAGACCGGCAATCCGGAGCAGATTGCCGAGCAGGCTCGGCTGGTCGCCATTGCCCGGGAAAGCGGCATGCTGC
TGCTCGGTCCGAACAGCATCGGCTATGCGAACTACATCAACCATGCGCTGGTGTCGTTCACGCCGCTGCCCGCGCGTGGC
GGCGAACTGCCGGCCCATGCGATCGGGCTGGTCAGCCAGTCCGGCGCGCTGGCATTTGCGCTGGAACAGGCGGCCAACCA
CGGCACGGCGTTCAGCCACGTGTTCTCGTGCGGCAATGCGTGCGATATCGACGTGACCGACCAGATCGCCTATCTCGCCG
GGGATCCCTCGTGCGCGGCGATCGCATGCGTATTCGAAGGGCTGTCCGACGCCAGCCGGATCATTCGCGCGGCGCAAGTC
TGCGCGGAAGCCGGCAAGCCGCTGGTGGTCTACAAGATGGCGCGCGGGACGGCGGGCGCGGCGGCGGCCATGTCGCATAC
CGGCTCGATGGCGGGATCCGACCGCGCCTACAGCACGGCGCTGCGCGAAGCTGGCGTGGTGCAGGTCGATACCATCGAGC
AGCTCGTGCCGACGACGGTGTTCTTCGCCAAGGCCCCCCGGCCGACGACGTCCGGCGTGGCCATCGTCTCGGGTTCGGGC
GGCGCGGGCATTGTCGCCGCCGACGAGGCCGAGCGTTTCAACGTGCCGCTGCCGCAGCCGTGTGACGCGACCCGCGCCGT
GCTCGAATCGCACATTCCTGACTTCGGCGCCGCGCGCAACCCGTGCGACCTGACCGCCCAGGCCGCCAACAACTTCGACT
CCTTCATCCAGTGCGGCGACGCGGTCTTCGCCGATCCCGCCTACGGCGCCGCCGTGGTGCCGCTGGTGGTGACCGGCGAC
GGCAACGGCCGCCGCTTCCAGGTGTTCAACGACCTAGCCGTCAAGCACGGCAAGATGGCGTGCGGCCTGTGGATGTCGAA
CTGGATGGAAGGGCCGGAGGCGGTCGAGTCCGAGGCGCTGCCGCGCCTTGCGCTGTTCCGCTCGGTCTCGCACTGCTTCG
CGGCGCTGGCCGCGTGGCAGGCACGGGAGCAATGGCTGTTGTCGCGCGCCACGCCGAAGCCGCCGCGCCTGACACACGCT
TCGGTGGCCGCCGAAGCGCGCGCGCGCATCGTTGCCGCGCCGGCCGATACGCTCACCGAGCGTGAAGCCAAGGACGTCCT
TGCCATGTACGGCGTGCCGGTGGTGGGCGAGTCCCTGGCGACGAGCGAGCAGGACGCCGTGCGCGCCGCCGATGCCTGCG
GCTATCCGGTCGTGCTGAAGGTCGAGAGCCCGGCCATCCCGCACAAGTCGGAAGCGGGCGTGATCCGCCTCGGCGTGAAC
TCGGCGCAGGAGGTTGCCGTCGCGTACCGCGAGGTCATGGCGAATGCGCGCAAGGTGACCGCCGACGACCGCATCAACGG
CGTGCTGGTGCAGAGCCAGGTGCCGACCGGCATCGAGATCTTGGTCGGCGCCCGCGTGGACCCGCACCTCGGCGCGCTGC
TGGTGGTGGGGCTGGGCGGGGTGATGGTCGAGCTGATGCAGGACACGGTCGCGACCATCGCGCCGTGCTCGGCGCAGCAG
GCGCGCGCCATGCTGGAGCAGCTGCGCGGCGTGGCGCTGCTGAAGGGCTTCCGCGGCGCGGCGGGCGTGGACATGGACCT
GCTGGCGGAAATCGTCGCCAGCCTGTCCGAGTTCGCGGCGGACCAGCGCGACGTGATCGCCGAGTTCGATGTGAATCCGC
TGATCTGCACGCCGGACCGCATCGTGGCGGTGGATGCGCTGATCGAACGGAGAGTGGGGGCCTGA

Upstream 100 bases:

>100_bases
GCCGCGCCGATCTGCTTCCTGCTGTCCGACGCCGCCGGCTACGTGCTGGGCCAGCACATCGGCGTGAACGGCGGCCTGCA
CATGGCGAGCTGAGGGCGGC

Downstream 100 bases:

>100_bases
CGGGCCGCTCCGGTGCCGGCGGGGAGGGCGTTCCCGCCGGCATCGGAAACATTCAGGCGGCGGCGCGAAGCGGCGCTTCG
ACCGCCGCCTCCTGGCTGGC

Product: Acetyl-CoA synthetase (NDP-forming)

Products: AMP; diphosphate; 6-carboxyhexanoyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MSTRDLYTHAQLRRLFHPRTIAVVGATPNARSFAGRAMTNLQQFDGNVLLVNPRYPEVNGQVCYPSLSALPEAPDCVLIA
TARETVEPIVRECAGLGVGGVVLFASGYAETGNPEQIAEQARLVAIARESGMLLLGPNSIGYANYINHALVSFTPLPARG
GELPAHAIGLVSQSGALAFALEQAANHGTAFSHVFSCGNACDIDVTDQIAYLAGDPSCAAIACVFEGLSDASRIIRAAQV
CAEAGKPLVVYKMARGTAGAAAAMSHTGSMAGSDRAYSTALREAGVVQVDTIEQLVPTTVFFAKAPRPTTSGVAIVSGSG
GAGIVAADEAERFNVPLPQPCDATRAVLESHIPDFGAARNPCDLTAQAANNFDSFIQCGDAVFADPAYGAAVVPLVVTGD
GNGRRFQVFNDLAVKHGKMACGLWMSNWMEGPEAVESEALPRLALFRSVSHCFAALAAWQAREQWLLSRATPKPPRLTHA
SVAAEARARIVAAPADTLTEREAKDVLAMYGVPVVGESLATSEQDAVRAADACGYPVVLKVESPAIPHKSEAGVIRLGVN
SAQEVAVAYREVMANARKVTADDRINGVLVQSQVPTGIEILVGARVDPHLGALLVVGLGGVMVELMQDTVATIAPCSAQQ
ARAMLEQLRGVALLKGFRGAAGVDMDLLAEIVASLSEFAADQRDVIAEFDVNPLICTPDRIVAVDALIERRVGA

Sequences:

>Translated_714_residues
MSTRDLYTHAQLRRLFHPRTIAVVGATPNARSFAGRAMTNLQQFDGNVLLVNPRYPEVNGQVCYPSLSALPEAPDCVLIA
TARETVEPIVRECAGLGVGGVVLFASGYAETGNPEQIAEQARLVAIARESGMLLLGPNSIGYANYINHALVSFTPLPARG
GELPAHAIGLVSQSGALAFALEQAANHGTAFSHVFSCGNACDIDVTDQIAYLAGDPSCAAIACVFEGLSDASRIIRAAQV
CAEAGKPLVVYKMARGTAGAAAAMSHTGSMAGSDRAYSTALREAGVVQVDTIEQLVPTTVFFAKAPRPTTSGVAIVSGSG
GAGIVAADEAERFNVPLPQPCDATRAVLESHIPDFGAARNPCDLTAQAANNFDSFIQCGDAVFADPAYGAAVVPLVVTGD
GNGRRFQVFNDLAVKHGKMACGLWMSNWMEGPEAVESEALPRLALFRSVSHCFAALAAWQAREQWLLSRATPKPPRLTHA
SVAAEARARIVAAPADTLTEREAKDVLAMYGVPVVGESLATSEQDAVRAADACGYPVVLKVESPAIPHKSEAGVIRLGVN
SAQEVAVAYREVMANARKVTADDRINGVLVQSQVPTGIEILVGARVDPHLGALLVVGLGGVMVELMQDTVATIAPCSAQQ
ARAMLEQLRGVALLKGFRGAAGVDMDLLAEIVASLSEFAADQRDVIAEFDVNPLICTPDRIVAVDALIERRVGA
>Mature_713_residues
STRDLYTHAQLRRLFHPRTIAVVGATPNARSFAGRAMTNLQQFDGNVLLVNPRYPEVNGQVCYPSLSALPEAPDCVLIAT
ARETVEPIVRECAGLGVGGVVLFASGYAETGNPEQIAEQARLVAIARESGMLLLGPNSIGYANYINHALVSFTPLPARGG
ELPAHAIGLVSQSGALAFALEQAANHGTAFSHVFSCGNACDIDVTDQIAYLAGDPSCAAIACVFEGLSDASRIIRAAQVC
AEAGKPLVVYKMARGTAGAAAAMSHTGSMAGSDRAYSTALREAGVVQVDTIEQLVPTTVFFAKAPRPTTSGVAIVSGSGG
AGIVAADEAERFNVPLPQPCDATRAVLESHIPDFGAARNPCDLTAQAANNFDSFIQCGDAVFADPAYGAAVVPLVVTGDG
NGRRFQVFNDLAVKHGKMACGLWMSNWMEGPEAVESEALPRLALFRSVSHCFAALAAWQAREQWLLSRATPKPPRLTHAS
VAAEARARIVAAPADTLTEREAKDVLAMYGVPVVGESLATSEQDAVRAADACGYPVVLKVESPAIPHKSEAGVIRLGVNS
AQEVAVAYREVMANARKVTADDRINGVLVQSQVPTGIEILVGARVDPHLGALLVVGLGGVMVELMQDTVATIAPCSAQQA
RAMLEQLRGVALLKGFRGAAGVDMDLLAEIVASLSEFAADQRDVIAEFDVNPLICTPDRIVAVDALIERRVGA

Specific function: Unknown

COG id: COG1042

COG function: function code C; Acyl-CoA synthetase (NDP forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yfiQ [H]

Homologues:

Organism=Escherichia coli, GI1788938, Length=714, Percent_Identity=26.6106442577031, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014089
- InterPro:   IPR013650
- InterPro:   IPR003781
- InterPro:   IPR016040
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF02629 CoA_binding [H]

EC number: 6.2.1.14

Molecular weight: Translated: 74746; Mature: 74615

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRDLYTHAQLRRLFHPRTIAVVGATPNARSFAGRAMTNLQQFDGNVLLVNPRYPEVNG
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
QVCYPSLSALPEAPDCVLIATARETVEPIVRECAGLGVGGVVLFASGYAETGNPEQIAEQ
EEECCCHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
ARLVAIARESGMLLLGPNSIGYANYINHALVSFTPLPARGGELPAHAIGLVSQSGALAFA
HHEEEEEECCCEEEECCCCCCHHHHHHHHHHEECCCCCCCCCCCHHHHHEECCCCCHHHH
LEQAANHGTAFSHVFSCGNACDIDVTDQIAYLAGDPSCAAIACVFEGLSDASRIIRAAQV
HHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHH
CAEAGKPLVVYKMARGTAGAAAAMSHTGSMAGSDRAYSTALREAGVVQVDTIEQLVPTTV
HHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHE
FFAKAPRPTTSGVAIVSGSGGAGIVAADEAERFNVPLPQPCDATRAVLESHIPDFGAARN
EEECCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
PCDLTAQAANNFDSFIQCGDAVFADPAYGAAVVPLVVTGDGNGRRFQVFNDLAVKHGKMA
CCCCCHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHCCCHH
CGLWMSNWMEGPEAVESEALPRLALFRSVSHCFAALAAWQAREQWLLSRATPKPPRLTHA
HHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
SVAAEARARIVAAPADTLTEREAKDVLAMYGVPVVGESLATSEQDAVRAADACGYPVVLK
HHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCCCEEEE
VESPAIPHKSEAGVIRLGVNSAQEVAVAYREVMANARKVTADDRINGVLVQSQVPTGIEI
ECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCCCCEEE
LVGARVDPHLGALLVVGLGGVMVELMQDTVATIAPCSAQQARAMLEQLRGVALLKGFRGA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
AGVDMDLLAEIVASLSEFAADQRDVIAEFDVNPLICTPDRIVAVDALIERRVGA
CCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STRDLYTHAQLRRLFHPRTIAVVGATPNARSFAGRAMTNLQQFDGNVLLVNPRYPEVNG
CCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
QVCYPSLSALPEAPDCVLIATARETVEPIVRECAGLGVGGVVLFASGYAETGNPEQIAEQ
EEECCCHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
ARLVAIARESGMLLLGPNSIGYANYINHALVSFTPLPARGGELPAHAIGLVSQSGALAFA
HHEEEEEECCCEEEECCCCCCHHHHHHHHHHEECCCCCCCCCCCHHHHHEECCCCCHHHH
LEQAANHGTAFSHVFSCGNACDIDVTDQIAYLAGDPSCAAIACVFEGLSDASRIIRAAQV
HHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHH
CAEAGKPLVVYKMARGTAGAAAAMSHTGSMAGSDRAYSTALREAGVVQVDTIEQLVPTTV
HHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHE
FFAKAPRPTTSGVAIVSGSGGAGIVAADEAERFNVPLPQPCDATRAVLESHIPDFGAARN
EEECCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
PCDLTAQAANNFDSFIQCGDAVFADPAYGAAVVPLVVTGDGNGRRFQVFNDLAVKHGKMA
CCCCCHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHCCCHH
CGLWMSNWMEGPEAVESEALPRLALFRSVSHCFAALAAWQAREQWLLSRATPKPPRLTHA
HHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
SVAAEARARIVAAPADTLTEREAKDVLAMYGVPVVGESLATSEQDAVRAADACGYPVVLK
HHHHHHHHEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCCCEEEE
VESPAIPHKSEAGVIRLGVNSAQEVAVAYREVMANARKVTADDRINGVLVQSQVPTGIEI
ECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCCCCEEE
LVGARVDPHLGALLVVGLGGVMVELMQDTVATIAPCSAQQARAMLEQLRGVALLKGFRGA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
AGVDMDLLAEIVASLSEFAADQRDVIAEFDVNPLICTPDRIVAVDALIERRVGA
CCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 6-carboxyhexanoate; CoA

Specific reaction: ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]