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The map label for this gene is fadE12 [H]

Identifier: 116694332

GI number: 116694332

Start: 430587

End: 431750

Strand: Direct

Name: fadE12 [H]

Synonym: H16_B0379

Alternate gene names: 116694332

Gene position: 430587-431750 (Clockwise)

Preceding gene: 116694331

Following gene: 116694333

Centisome position: 14.78

GC content: 69.33

Gene sequence:

>1164_bases
GTGACTGCAAGTCTCGAATCGTTGCCGCTCGTCGCCATCCCGCCGGCGGACGAAGCGCTGCGCGGCCCGATCCGCGCATT
CCTCGAAGGAAAGCTGGCCAACGTGCCGACGCATATCCGCGCCCGCACCTGGATGGGCTATGACGCCGACTTCAGCCGCG
CGCTCGCGAAACAGGGCTGGCTCGGCCTCGCCCTGCCAAAGGAGTATGGCGGCGCCGGCCGCAGCGCATTCGCCCGCTTC
GTGCTGGTGGAGGAACTGATCGCCGCCGGTGCGCCGGTGTCGGCCCACTGGTTCGCCGATCGCCAGACCGCCCCGCTGAT
CCTGAAGTTCGGCACGCCGGCACAGCGCGAGTTTTTCGTCCCGCGCATGGTGCGCGGCGAGATCTTCATGTGCATCGGCA
TGAGCGAGCCCGACACCGGCTCCGATCTCTCCAGCGTGCGCACGCGCGCCGTACGCACCGGCACGGGCTGGCGCCTGAAC
GGCCGCAAGATCTGGACGACCAATGCCCACCGCACGCAGTACATGTGCGCGCTGGTGCGGACGTCGGGCCAGCACGGCGA
CCGCCACAAGGGCCTGTCGCAGGTACTGATCGACCTCAGCCTGCCCGGCATCAGCTACCGCCCGATCAAGGACCTCGCCG
GCGACGCGCACTTCTGCGAAGTCGTCTTCGAGGACGTGGACCTGCCGGCCGACGCCATCGTCGGCGAAGAAGGCTCGGGC
TGGAAGCAGGTGACTGCGGAACTTGCCTTCGAGCGCAGCGGACCGGAGCGCATCCTGACCAGCCAGCTGCTGGCCGAGAC
GTGGCTGGCCGAAGTGCGTGCGTCGGGCCTTGCCGTGCCCGATTCGGTGAAGGTCATCGCCGGCCGCATCGCCGGCCGCC
TGGCGGCGCTTCGCACGATGTCGCTCGCCGTCGCCGACCTGCTCGACAAGGGCCAGAACCCCGAGACCGACGCCGCCTAC
GTGAAGGACCTCGGCACCGAGTTCGAGCAGACCGTGCCGGGCTGGATTGCCTCGGCCATCGAGCAGATGCCGGACTTCGC
GCCGTCGGAGACGCTGCAACGCGCGCTCGCCTACATCACGCAGCTTTGCCCGAGCTTCTCGCTGCGCGGCGGCACCCGCC
AGATCCTGCGCGGCATCATCGCCCGCTCGCTGGGCCTGCGCTAA

Upstream 100 bases:

>100_bases
GCCGGCTTCAGTGCCGACGAGATCCGCAAGCTCGCGGAAGAGGGCGTGACGCTGATCGCGCCCGCCACCGAGTGATACCC
CCACATTCCGGAGTTTCATC

Downstream 100 bases:

>100_bases
GACATTACCGGAGACGACCATGACTGATTCCCTCCTGGAAGGCTTCGAGCGCGCCCTCGCCGACCTGTGTGCCGACGAAG
CGGTACGCCGCAGCGAAGCG

Product: Acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTASLESLPLVAIPPADEALRGPIRAFLEGKLANVPTHIRARTWMGYDADFSRALAKQGWLGLALPKEYGGAGRSAFARF
VLVEELIAAGAPVSAHWFADRQTAPLILKFGTPAQREFFVPRMVRGEIFMCIGMSEPDTGSDLSSVRTRAVRTGTGWRLN
GRKIWTTNAHRTQYMCALVRTSGQHGDRHKGLSQVLIDLSLPGISYRPIKDLAGDAHFCEVVFEDVDLPADAIVGEEGSG
WKQVTAELAFERSGPERILTSQLLAETWLAEVRASGLAVPDSVKVIAGRIAGRLAALRTMSLAVADLLDKGQNPETDAAY
VKDLGTEFEQTVPGWIASAIEQMPDFAPSETLQRALAYITQLCPSFSLRGGTRQILRGIIARSLGLR

Sequences:

>Translated_387_residues
MTASLESLPLVAIPPADEALRGPIRAFLEGKLANVPTHIRARTWMGYDADFSRALAKQGWLGLALPKEYGGAGRSAFARF
VLVEELIAAGAPVSAHWFADRQTAPLILKFGTPAQREFFVPRMVRGEIFMCIGMSEPDTGSDLSSVRTRAVRTGTGWRLN
GRKIWTTNAHRTQYMCALVRTSGQHGDRHKGLSQVLIDLSLPGISYRPIKDLAGDAHFCEVVFEDVDLPADAIVGEEGSG
WKQVTAELAFERSGPERILTSQLLAETWLAEVRASGLAVPDSVKVIAGRIAGRLAALRTMSLAVADLLDKGQNPETDAAY
VKDLGTEFEQTVPGWIASAIEQMPDFAPSETLQRALAYITQLCPSFSLRGGTRQILRGIIARSLGLR
>Mature_386_residues
TASLESLPLVAIPPADEALRGPIRAFLEGKLANVPTHIRARTWMGYDADFSRALAKQGWLGLALPKEYGGAGRSAFARFV
LVEELIAAGAPVSAHWFADRQTAPLILKFGTPAQREFFVPRMVRGEIFMCIGMSEPDTGSDLSSVRTRAVRTGTGWRLNG
RKIWTTNAHRTQYMCALVRTSGQHGDRHKGLSQVLIDLSLPGISYRPIKDLAGDAHFCEVVFEDVDLPADAIVGEEGSGW
KQVTAELAFERSGPERILTSQLLAETWLAEVRASGLAVPDSVKVIAGRIAGRLAALRTMSLAVADLLDKGQNPETDAAYV
KDLGTEFEQTVPGWIASAIEQMPDFAPSETLQRALAYITQLCPSFSLRGGTRQILRGIIARSLGLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=312, Percent_Identity=27.2435897435897, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI226958414, Length=282, Percent_Identity=27.6595744680851, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557233, Length=248, Percent_Identity=29.8387096774194, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4501857, Length=240, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI4501859, Length=252, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI76496475, Length=215, Percent_Identity=29.3023255813954, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4557235, Length=215, Percent_Identity=29.3023255813954, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7656849, Length=197, Percent_Identity=28.4263959390863, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI21361497, Length=196, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI187960098, Length=201, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4557231, Length=201, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI87081958, Length=298, Percent_Identity=26.8456375838926, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786223, Length=285, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=317, Percent_Identity=29.3375394321767, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17551932, Length=213, Percent_Identity=33.8028169014084, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=239, Percent_Identity=28.0334728033473, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=205, Percent_Identity=32.1951219512195, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=196, Percent_Identity=30.1020408163265, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=187, Percent_Identity=31.0160427807487, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=204, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=395, Percent_Identity=24.8101265822785, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=211, Percent_Identity=30.3317535545024, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=211, Percent_Identity=30.3317535545024, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=201, Percent_Identity=27.363184079602, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=200, Percent_Identity=24, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355753, Length=281, Percent_Identity=28.4697508896797, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281363737, Length=206, Percent_Identity=29.126213592233, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666513, Length=300, Percent_Identity=26, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356377, Length=238, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646207, Length=247, Percent_Identity=27.1255060728745, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24660351, Length=219, Percent_Identity=26.4840182648402, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42067; Mature: 41936

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASLESLPLVAIPPADEALRGPIRAFLEGKLANVPTHIRARTWMGYDADFSRALAKQGW
CCCCCCCCCEEEECCCCHHHHHHHHHHHCCHHCCCCCHHEEEEECCCCHHHHHHHHHCCC
LGLALPKEYGGAGRSAFARFVLVEELIAAGAPVSAHWFADRQTAPLILKFGTPAQREFFV
EEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCHHHCC
PRMVRGEIFMCIGMSEPDTGSDLSSVRTRAVRTGTGWRLNGRKIWTTNAHRTQYMCALVR
CHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCEEEEECCCCHHHHHHHHHH
TSGQHGDRHKGLSQVLIDLSLPGISYRPIKDLAGDAHFCEVVFEDVDLPADAIVGEEGSG
HCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCC
WKQVTAELAFERSGPERILTSQLLAETWLAEVRASGLAVPDSVKVIAGRIAGRLAALRTM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SLAVADLLDKGQNPETDAAYVKDLGTEFEQTVPGWIASAIEQMPDFAPSETLQRALAYIT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
QLCPSFSLRGGTRQILRGIIARSLGLR
HHCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TASLESLPLVAIPPADEALRGPIRAFLEGKLANVPTHIRARTWMGYDADFSRALAKQGW
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHCCCCCHHEEEEECCCCHHHHHHHHHCCC
LGLALPKEYGGAGRSAFARFVLVEELIAAGAPVSAHWFADRQTAPLILKFGTPAQREFFV
EEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCHHHCC
PRMVRGEIFMCIGMSEPDTGSDLSSVRTRAVRTGTGWRLNGRKIWTTNAHRTQYMCALVR
CHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCEEEEECCCCHHHHHHHHHH
TSGQHGDRHKGLSQVLIDLSLPGISYRPIKDLAGDAHFCEVVFEDVDLPADAIVGEEGSG
HCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCC
WKQVTAELAFERSGPERILTSQLLAETWLAEVRASGLAVPDSVKVIAGRIAGRLAALRTM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SLAVADLLDKGQNPETDAAYVKDLGTEFEQTVPGWIASAIEQMPDFAPSETLQRALAYIT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
QLCPSFSLRGGTRQILRGIIARSLGLR
HHCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]