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The map label for this gene is kipR [H]

Identifier: 116694304

GI number: 116694304

Start: 395642

End: 396412

Strand: Direct

Name: kipR [H]

Synonym: H16_B0350

Alternate gene names: 116694304

Gene position: 395642-396412 (Clockwise)

Preceding gene: 116694298

Following gene: 116694317

Centisome position: 13.58

GC content: 64.98

Gene sequence:

>771_bases
ATGAATGCGAATAGTGATCCAAGGGGCGCCTCAAAAGGCGACGATGGCGCTGGGGGCGTCATAGCGGTCACCCGCGCCCT
GCGCGTACTCGAGGCGTTCGGGGTGAACGACCCCCAGCTCTCACTTGCCGAACTGAGCCGGCGGACCGGCATCCACAAGA
CCACCGTGCTGCGGCTGGCGCGCACGCTGGCGGCGGACAACTATCTGGTGCAGAAGGAAGACGGCAACTGGCGGCTCGGC
CGCGCAGCCGGGTGGCTGGGCGCGTGCTACCAGGCCACCTTCAACGTTCAGGAAGTGGTGGAGCCGGTGCTGCGGGAGCT
GACGATCAAGACCGGCGAAAGCGCTTCGTTCTACGTCCGGGAGGGACAACAGCGAACCTGCCTCGTCCGGGTCGAAGGAC
CGCAGGCCATCCGGCATCACGTCAGGATCGGGGCGGCCCTGCCGCTGGACAGCGGTTCGCCAGGCCGCGTCATCCTGGCG
TTCTCAGGTGAGCCGGGCGAGCTTTATGAAATGATCCGCCGCCGTGGATTTCATCTGTCGCTCGGCGAGCGCGAGGCCGA
AGTCTCGAGCGTGTCGGCACCGGTTTTCGGATTGCACTGGCGGCTGCTAGGCTCCATGTGCATTTCGGGACCGACCGCCC
GGCTAAGCGAAGAGCGTTTGCTGGAGCTGGCACAGACAGTCGTCGACGCGGCGAACAAGCTTTCGTATGCCATGGCAGGA
AGCCAACGGCCTGCGATGCAAATTGAAAGGCCGTCGACCTGGCACCCTTGA

Upstream 100 bases:

>100_bases
CATTACAGTCTCCGAATCTCGGTTTCGTTGTGCTTCGGATTGTGGTCGACCGTTTCACGGCATACAATGCTGTTTCATAC
CGTGCACCGCGTTTCGTTCT

Downstream 100 bases:

>100_bases
GATTGCAGATGTGGGGCAAGGAGAGCCGATAGAAATCTTAGATGACCTCTGTCAGTCGCGAGCCGGGCGTCGGTTTTCGA
CTGCGGATTCAACCGGTCGA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNANSDPRGASKGDDGAGGVIAVTRALRVLEAFGVNDPQLSLAELSRRTGIHKTTVLRLARTLAADNYLVQKEDGNWRLG
RAAGWLGACYQATFNVQEVVEPVLRELTIKTGESASFYVREGQQRTCLVRVEGPQAIRHHVRIGAALPLDSGSPGRVILA
FSGEPGELYEMIRRRGFHLSLGEREAEVSSVSAPVFGLHWRLLGSMCISGPTARLSEERLLELAQTVVDAANKLSYAMAG
SQRPAMQIERPSTWHP

Sequences:

>Translated_256_residues
MNANSDPRGASKGDDGAGGVIAVTRALRVLEAFGVNDPQLSLAELSRRTGIHKTTVLRLARTLAADNYLVQKEDGNWRLG
RAAGWLGACYQATFNVQEVVEPVLRELTIKTGESASFYVREGQQRTCLVRVEGPQAIRHHVRIGAALPLDSGSPGRVILA
FSGEPGELYEMIRRRGFHLSLGEREAEVSSVSAPVFGLHWRLLGSMCISGPTARLSEERLLELAQTVVDAANKLSYAMAG
SQRPAMQIERPSTWHP
>Mature_256_residues
MNANSDPRGASKGDDGAGGVIAVTRALRVLEAFGVNDPQLSLAELSRRTGIHKTTVLRLARTLAADNYLVQKEDGNWRLG
RAAGWLGACYQATFNVQEVVEPVLRELTIKTGESASFYVREGQQRTCLVRVEGPQAIRHHVRIGAALPLDSGSPGRVILA
FSGEPGELYEMIRRRGFHLSLGEREAEVSSVSAPVFGLHWRLLGSMCISGPTARLSEERLLELAQTVVDAANKLSYAMAG
SQRPAMQIERPSTWHP

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=25.0996015936255, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786468, Length=246, Percent_Identity=24.7967479674797, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786715, Length=252, Percent_Identity=22.2222222222222, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27869; Mature: 27869

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANSDPRGASKGDDGAGGVIAVTRALRVLEAFGVNDPQLSLAELSRRTGIHKTTVLRLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
RTLAADNYLVQKEDGNWRLGRAAGWLGACYQATFNVQEVVEPVLRELTIKTGESASFYVR
HHHHHCCEEEEECCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEE
EGQQRTCLVRVEGPQAIRHHVRIGAALPLDSGSPGRVILAFSGEPGELYEMIRRRGFHLS
CCCCCEEEEEECCHHHHHHHHHHCEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEE
LGEREAEVSSVSAPVFGLHWRLLGSMCISGPTARLSEERLLELAQTVVDAANKLSYAMAG
CCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCC
SQRPAMQIERPSTWHP
CCCCCEEECCCCCCCC
>Mature Secondary Structure
MNANSDPRGASKGDDGAGGVIAVTRALRVLEAFGVNDPQLSLAELSRRTGIHKTTVLRLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
RTLAADNYLVQKEDGNWRLGRAAGWLGACYQATFNVQEVVEPVLRELTIKTGESASFYVR
HHHHHCCEEEEECCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEE
EGQQRTCLVRVEGPQAIRHHVRIGAALPLDSGSPGRVILAFSGEPGELYEMIRRRGFHLS
CCCCCEEEEEECCHHHHHHHHHHCEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEE
LGEREAEVSSVSAPVFGLHWRLLGSMCISGPTARLSEERLLELAQTVVDAANKLSYAMAG
CCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCC
SQRPAMQIERPSTWHP
CCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]