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The map label for this gene is galE [H]

Identifier: 116694181

GI number: 116694181

Start: 252279

End: 253298

Strand: Direct

Name: galE [H]

Synonym: H16_B0226

Alternate gene names: 116694181

Gene position: 252279-253298 (Clockwise)

Preceding gene: 116694180

Following gene: 116694183

Centisome position: 8.66

GC content: 64.41

Gene sequence:

>1020_bases
ATGCCTGAAACCTTGCTCCTGACCGGTGCCACCGGCTATATCGCCTCGCATACCTGGGTTGCACTGCTCAATGCCGGCTA
CCACGTGATCGGCCTGGATAATCTTTGCAACAGCAGCCCGGTGGTGCTGGAGCGGCTCGCCACCATTACCGGCAAGACCC
CGCATTTTGTGCAGGGCGACGTGCGCGACCGCGCATTGCTGGACCGGCTCTTTACCGAACACCGCATCAGCGGGGTGATT
CATTTTGCCGCACTCAAGGCAGTGGGCGAATCGGTGAGCCAGCCGCTGGAGTATTACAGCAACAACCTGGGCGGGCTGCT
GACGGTATGCGCGGCAATGGGCGCGGCCGGGGTGAAACAGCTGGTGTTCAGTTCTTCGGCCACGGTTTATGGCAATCCCC
ATGCGGTGCCGATCCTGGAGGATTTCCCGCTGTCGGCCACCAACCCGTATGGCCAGACCAAGCTGATGGGCGAGCAAATC
CTGCGCGACCTGGAAACATCGGATCCGGACTGGCGCATTGCCTACCTGCGTTATTTCAATCCGGTCGGCGCGCATGAAAG
CGGGCTGATTGGCGAGGATCCGCGCGGTATCCCGAACAACCTGATGCCGTATGTGGCGCAGGTGGCCGGCGGGCGCCGTG
AAAAGCTGATGGTATTCGGCGGTGACTACCCGACGCCGGACGGCACCGGCGTGCGCGACTATATCCACGTCTGCGACCTG
GCGGACGGCCACCTGGCGGCGCTGGGTTACCTGCGCGCGCAGGGCAAGAGCATGACCGTGAACCTGGGAACGGGCCGCGG
CTACAGCGTGCTGGAAGTGGTGCAGGCCTACCAGCGTGCCAGCGGCAAGCCGGTGCCGCATGAGATCGTGGCGCGGCGCC
CGGGCGACATCGCCTCGTGCTACGCCGATCCCGCGCTGGCCAACCAGCTGCTGGGCTGGCGCGCGCGCCATGACATCGAC
CGCATGTGCCAGGACTCATGGCGCTGGCAGTCGATGAATCCGCAGGGGTTTGACGCCTGA

Upstream 100 bases:

>100_bases
AGCTTCGCCGGCCTACGCGGCGGAAAGAGGTGCTTGCGCCACGTTTTGAATCCGCCAGGCCAAGGCCCGGCCCTGAATCG
AATTCCGACACCGATTTTCC

Downstream 100 bases:

>100_bases
CGCCCCGGGCAGGTGGCGCCGCAGTGTTGTGCAGGCGCCGCGGAAGACCAGAAAACAAAAACGCCACGGAATTCATCCGT
GGCGTTTTACCATCTGCCGG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MPETLLLTGATGYIASHTWVALLNAGYHVIGLDNLCNSSPVVLERLATITGKTPHFVQGDVRDRALLDRLFTEHRISGVI
HFAALKAVGESVSQPLEYYSNNLGGLLTVCAAMGAAGVKQLVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQI
LRDLETSDPDWRIAYLRYFNPVGAHESGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
ADGHLAALGYLRAQGKSMTVNLGTGRGYSVLEVVQAYQRASGKPVPHEIVARRPGDIASCYADPALANQLLGWRARHDID
RMCQDSWRWQSMNPQGFDA

Sequences:

>Translated_339_residues
MPETLLLTGATGYIASHTWVALLNAGYHVIGLDNLCNSSPVVLERLATITGKTPHFVQGDVRDRALLDRLFTEHRISGVI
HFAALKAVGESVSQPLEYYSNNLGGLLTVCAAMGAAGVKQLVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQI
LRDLETSDPDWRIAYLRYFNPVGAHESGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
ADGHLAALGYLRAQGKSMTVNLGTGRGYSVLEVVQAYQRASGKPVPHEIVARRPGDIASCYADPALANQLLGWRARHDID
RMCQDSWRWQSMNPQGFDA
>Mature_338_residues
PETLLLTGATGYIASHTWVALLNAGYHVIGLDNLCNSSPVVLERLATITGKTPHFVQGDVRDRALLDRLFTEHRISGVIH
FAALKAVGESVSQPLEYYSNNLGGLLTVCAAMGAAGVKQLVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQIL
RDLETSDPDWRIAYLRYFNPVGAHESGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDLA
DGHLAALGYLRAQGKSMTVNLGTGRGYSVLEVVQAYQRASGKPVPHEIVARRPGDIASCYADPALANQLLGWRARHDIDR
MCQDSWRWQSMNPQGFDA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=56.3953488372093, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=56.3953488372093, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=56.3953488372093, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=28.4172661870504, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=56.5868263473054, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI48994969, Length=362, Percent_Identity=26.2430939226519, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=52.7536231884058, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=52.7377521613833, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=49.7093023255814, Blast_Score=336, Evalue=3e-93,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=55.3623188405797, Blast_Score=390, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36848; Mature: 36717

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETLLLTGATGYIASHTWVALLNAGYHVIGLDNLCNSSPVVLERLATITGKTPHFVQGD
CCCCEEEECCCCHHHHHHHHHHHHCCEEEEECHHHCCCCHHHHHHHHHHCCCCCCCCCCC
VRDRALLDRLFTEHRISGVIHFAALKAVGESVSQPLEYYSNNLGGLLTVCAAMGAAGVKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQILRDLETSDPDWRIAYLRYFN
HHHCCCCEECCCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECC
PVGAHESGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC
ADGHLAALGYLRAQGKSMTVNLGTGRGYSVLEVVQAYQRASGKPVPHEIVARRPGDIASC
CCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHH
YADPALANQLLGWRARHDIDRMCQDSWRWQSMNPQGFDA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PETLLLTGATGYIASHTWVALLNAGYHVIGLDNLCNSSPVVLERLATITGKTPHFVQGD
CCCEEEECCCCHHHHHHHHHHHHCCEEEEECHHHCCCCHHHHHHHHHHCCCCCCCCCCC
VRDRALLDRLFTEHRISGVIHFAALKAVGESVSQPLEYYSNNLGGLLTVCAAMGAAGVKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQILRDLETSDPDWRIAYLRYFN
HHHCCCCEECCCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECC
PVGAHESGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC
ADGHLAALGYLRAQGKSMTVNLGTGRGYSVLEVVQAYQRASGKPVPHEIVARRPGDIASC
CCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHH
YADPALANQLLGWRARHDIDRMCQDSWRWQSMNPQGFDA
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]