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The map label for this gene is gbpR [H]

Identifier: 116694169

GI number: 116694169

Start: 241518

End: 242474

Strand: Direct

Name: gbpR [H]

Synonym: H16_B0214

Alternate gene names: 116694169

Gene position: 241518-242474 (Clockwise)

Preceding gene: 116694166

Following gene: 116694170

Centisome position: 8.29

GC content: 69.91

Gene sequence:

>957_bases
ATGAAATCCACCCTCGACGCCCTGACCGGCCGGTTGCGCATGAAGCAGCTGCAACTGCTGATCGCGCTGGACGAGCATTC
CTCCCTGCACCAGGCCGCCGCGGCGATGGCGATGACCCAGTCGGCGGCCAGCAAGTCGCTGCAGGAGCTGGAAGGCATGC
TGGAAGCGCCGCTGTTCGAGCGCTCCAGGCGCGGCATGCGTCCCAATGCCTTCGGCCATTGCGTAATCCGGCACGCACGC
CAGCTGGTGGCCGACCTGGGCGCCATGTGCGAGGAGGTAGCGGGCATCCGCGCGGGCAGCGGCGGGCGCGTGGCCATCGG
CGTGATCATGGGGGCGGTGCCGGAGGTGCTGGTGCCGGTGCTGGCGCGGCTGCGCCAGGCGCAGCCGGAGCTGGCGCTGG
AGATCATCGAGGACACCAGCCTGCGCCTGCTGGGGCTGCTCGACGACGGCCACCTCGACCTGGTGATCGGCCGCTCGCTG
GTCAGCGATGAACCGGCCCGCTACCACTACCACCCGCTGGGCGATGAGCAGGTCGCGGTCGTGGTGGGCCATGCGCATCC
GGCACCGCGCGCGCGCGCGATGGGGTTTGCCGACCTCGCAGGTTATCGCTGGATCACCTATGCAGGCCATATGCCGATGC
ACGCGCTGCTGCAGCGCGAGCTGGACCTGGCCGGCATGAGCTTTCCCGCCAATGCGATCTCGACCTCGTCGGCCTTCGTC
ACGGTGGCCATGCTGCAGGGCGACCCCGGGCTGGTGTCGCTGCTGCCGACCGGCGTGGCGGCGATGTTCGTGCGCCAGAA
GATGCTGCGCATCCTGCCCGTGCGGCTGCAGTCGCGGCAGCAGACTTTTGGCATCGTGACGCGGCGCGGCGGCGCCTTGT
CCGCGGCGGCGCGACAGCTGGTCGCGATCCTGAAGGCATTGCCGCGCACTGCGCAGCAGGCGGCTGCCGAGGTATAA

Upstream 100 bases:

>100_bases
TGCTTGTGAATTGGATCGGGCCAATATACGAGCCGCCATCCGGGCTGTATATTGAAACCTTTCCATCTGGTGATCGCTTT
TGCGACTCACAGATTTCTTC

Downstream 100 bases:

>100_bases
CGCCAGGTGATCGCCAGTTCAAAAAACATCAGTAGTGGCGAATCACTGATGCTCCTATAGTCTGCCCATCCGCGCCGCAG
AGCCGGACAGCAAAACGACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKSTLDALTGRLRMKQLQLLIALDEHSSLHQAAAAMAMTQSAASKSLQELEGMLEAPLFERSRRGMRPNAFGHCVIRHAR
QLVADLGAMCEEVAGIRAGSGGRVAIGVIMGAVPEVLVPVLARLRQAQPELALEIIEDTSLRLLGLLDDGHLDLVIGRSL
VSDEPARYHYHPLGDEQVAVVVGHAHPAPRARAMGFADLAGYRWITYAGHMPMHALLQRELDLAGMSFPANAISTSSAFV
TVAMLQGDPGLVSLLPTGVAAMFVRQKMLRILPVRLQSRQQTFGIVTRRGGALSAAARQLVAILKALPRTAQQAAAEV

Sequences:

>Translated_318_residues
MKSTLDALTGRLRMKQLQLLIALDEHSSLHQAAAAMAMTQSAASKSLQELEGMLEAPLFERSRRGMRPNAFGHCVIRHAR
QLVADLGAMCEEVAGIRAGSGGRVAIGVIMGAVPEVLVPVLARLRQAQPELALEIIEDTSLRLLGLLDDGHLDLVIGRSL
VSDEPARYHYHPLGDEQVAVVVGHAHPAPRARAMGFADLAGYRWITYAGHMPMHALLQRELDLAGMSFPANAISTSSAFV
TVAMLQGDPGLVSLLPTGVAAMFVRQKMLRILPVRLQSRQQTFGIVTRRGGALSAAARQLVAILKALPRTAQQAAAEV
>Mature_318_residues
MKSTLDALTGRLRMKQLQLLIALDEHSSLHQAAAAMAMTQSAASKSLQELEGMLEAPLFERSRRGMRPNAFGHCVIRHAR
QLVADLGAMCEEVAGIRAGSGGRVAIGVIMGAVPEVLVPVLARLRQAQPELALEIIEDTSLRLLGLLDDGHLDLVIGRSL
VSDEPARYHYHPLGDEQVAVVVGHAHPAPRARAMGFADLAGYRWITYAGHMPMHALLQRELDLAGMSFPANAISTSSAFV
TVAMLQGDPGLVSLLPTGVAAMFVRQKMLRILPVRLQSRQQTFGIVTRRGGALSAAARQLVAILKALPRTAQQAAAEV

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=214, Percent_Identity=27.5700934579439, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081904, Length=302, Percent_Identity=25.8278145695364, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=25.4180602006689, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=300, Percent_Identity=22.6666666666667, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=284, Percent_Identity=22.5352112676056, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=24.4186046511628, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34142; Mature: 34142

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTLDALTGRLRMKQLQLLIALDEHSSLHQAAAAMAMTQSAASKSLQELEGMLEAPLFE
CCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
RSRRGMRPNAFGHCVIRHARQLVADLGAMCEEVAGIRAGSGGRVAIGVIMGAVPEVLVPV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
LARLRQAQPELALEIIEDTSLRLLGLLDDGHLDLVIGRSLVSDEPARYHYHPLGDEQVAV
HHHHHHCCHHHHHHHHHCCCEEEEEEECCCCEEEEECHHHHCCCCCCEECCCCCCCCEEE
VVGHAHPAPRARAMGFADLAGYRWITYAGHMPMHALLQRELDLAGMSFPANAISTSSAFV
EEECCCCCCHHHHCCHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEE
TVAMLQGDPGLVSLLPTGVAAMFVRQKMLRILPVRLQSRQQTFGIVTRRGGALSAAARQL
EEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VAILKALPRTAQQAAAEV
HHHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MKSTLDALTGRLRMKQLQLLIALDEHSSLHQAAAAMAMTQSAASKSLQELEGMLEAPLFE
CCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
RSRRGMRPNAFGHCVIRHARQLVADLGAMCEEVAGIRAGSGGRVAIGVIMGAVPEVLVPV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
LARLRQAQPELALEIIEDTSLRLLGLLDDGHLDLVIGRSLVSDEPARYHYHPLGDEQVAV
HHHHHHCCHHHHHHHHHCCCEEEEEEECCCCEEEEECHHHHCCCCCCEECCCCCCCCEEE
VVGHAHPAPRARAMGFADLAGYRWITYAGHMPMHALLQRELDLAGMSFPANAISTSSAFV
EEECCCCCCHHHHCCHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEE
TVAMLQGDPGLVSLLPTGVAAMFVRQKMLRILPVRLQSRQQTFGIVTRRGGALSAAARQL
EEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VAILKALPRTAQQAAAEV
HHHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]