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The map label for this gene is gbpR [H]

Identifier: 116694166

GI number: 116694166

Start: 237938

End: 238864

Strand: Direct

Name: gbpR [H]

Synonym: H16_B0211

Alternate gene names: 116694166

Gene position: 237938-238864 (Clockwise)

Preceding gene: 116694165

Following gene: 116694169

Centisome position: 8.17

GC content: 70.44

Gene sequence:

>927_bases
ATGATCCCACCCGTCAGCACCCTCCACGGCCGCCTGAAAATGCAGCACCTGCGCCTGCTGCTGGCGGTGGAGGAGCGCGG
TTCGCTGCGCCAGGCCGCCGAGGCGCTGACGCTGACGCAGCCCGCGGTCAGCAAGATGCTGCAGGACATGGAGGACCTGC
TCGGCGTGCCGCTGTTCGAGCGCCATGCGCGCGGGCTGCGGCCCACGCGCTTCGGTCTGGCGGCCACGCGCTATGCCCGG
CTGGTGTTTGCCGACATGGGCGGGCTGCGCGATGAACTGGTGGCGCTGGAGTCCGGCAAGATCGGACGCGTGCGGGTCGG
GGCGGTGATGGCGCCTACACCGGGGCTGCTTGCCGACGTGATCCGGCAGCTCAATCGCGATCATCCGCGGCTGGAGGTGG
CGGTGCACGTGGAGACCAGCGATGTGCTGATGCCGCAGCTTGAGCGCGACCAGCTCGATATCGTGCTGGGGCGCGTGCCG
GATGGCTGGGACAGCAGCGGGCTGGACTTCGAGCAACTGGGCGACGAGGGCCTGGCTATCGTGGTCGGGCCGCAGCACCC
GCTGGCGCGGCGCCGCAAGCTGTCGTTCGAGGAACTGACGGGCTACCCGTGGATCATGCAGCCGCGCCCCAGCCCGATGC
GCGCGCTGATCGACCGCTCGTTCGAGGATGCCGGCGTGCCGGCGCCGCCGTCGACCATCGAGACCGCGGCGGTGCTGATG
ACCACGTCGTTGCTGGCGGACAGCGAACTGATCGCGGTGCTGCCGGAGTCGGTCGCCGCCTACTACGGCAGGCTTGGCGC
GCTGGCGGTATTGCCGCTGCCCCTGCCGCGCAAGCTGGGGCCCTATGGCATCGTCACGCGGCGGGGCCGCCCGCCGACGG
CATCGATGAGCCTGCTGATCGATGCGTTGCGGGCATTGTCGAGGTGA

Upstream 100 bases:

>100_bases
GCAGTGATATATCCGGCTTGACCATACGGGGCGAAGCGATAAGAATTTGTGATCGCAGGCGAAAGCCTGCCCTCACGCTT
CTCTACGCTTGGTCCCACCC

Downstream 100 bases:

>100_bases
GCCTCAGCCGGGCATCCCTTGCAGCTTGCCGTCGAGGCGCCACGCGTGGCGTTGCGGGCTGTCCGGGCGCAGCGACGCGG
GCAGCAGGCCGGGCGGCATG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MIPPVSTLHGRLKMQHLRLLLAVEERGSLRQAAEALTLTQPAVSKMLQDMEDLLGVPLFERHARGLRPTRFGLAATRYAR
LVFADMGGLRDELVALESGKIGRVRVGAVMAPTPGLLADVIRQLNRDHPRLEVAVHVETSDVLMPQLERDQLDIVLGRVP
DGWDSSGLDFEQLGDEGLAIVVGPQHPLARRRKLSFEELTGYPWIMQPRPSPMRALIDRSFEDAGVPAPPSTIETAAVLM
TTSLLADSELIAVLPESVAAYYGRLGALAVLPLPLPRKLGPYGIVTRRGRPPTASMSLLIDALRALSR

Sequences:

>Translated_308_residues
MIPPVSTLHGRLKMQHLRLLLAVEERGSLRQAAEALTLTQPAVSKMLQDMEDLLGVPLFERHARGLRPTRFGLAATRYAR
LVFADMGGLRDELVALESGKIGRVRVGAVMAPTPGLLADVIRQLNRDHPRLEVAVHVETSDVLMPQLERDQLDIVLGRVP
DGWDSSGLDFEQLGDEGLAIVVGPQHPLARRRKLSFEELTGYPWIMQPRPSPMRALIDRSFEDAGVPAPPSTIETAAVLM
TTSLLADSELIAVLPESVAAYYGRLGALAVLPLPLPRKLGPYGIVTRRGRPPTASMSLLIDALRALSR
>Mature_308_residues
MIPPVSTLHGRLKMQHLRLLLAVEERGSLRQAAEALTLTQPAVSKMLQDMEDLLGVPLFERHARGLRPTRFGLAATRYAR
LVFADMGGLRDELVALESGKIGRVRVGAVMAPTPGLLADVIRQLNRDHPRLEVAVHVETSDVLMPQLERDQLDIVLGRVP
DGWDSSGLDFEQLGDEGLAIVVGPQHPLARRRKLSFEELTGYPWIMQPRPSPMRALIDRSFEDAGVPAPPSTIETAAVLM
TTSLLADSELIAVLPESVAAYYGRLGALAVLPLPLPRKLGPYGIVTRRGRPPTASMSLLIDALRALSR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=294, Percent_Identity=29.2517006802721, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787601, Length=299, Percent_Identity=25.752508361204, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI157672245, Length=263, Percent_Identity=27.3764258555133, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790399, Length=297, Percent_Identity=26.5993265993266, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790262, Length=255, Percent_Identity=26.2745098039216, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789506, Length=295, Percent_Identity=20.6779661016949, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786508, Length=165, Percent_Identity=29.6969696969697, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI145693105, Length=211, Percent_Identity=24.1706161137441, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=23.6, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=196, Percent_Identity=26.530612244898, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33677; Mature: 33677

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPPVSTLHGRLKMQHLRLLLAVEERGSLRQAAEALTLTQPAVSKMLQDMEDLLGVPLFE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHH
RHARGLRPTRFGLAATRYARLVFADMGGLRDELVALESGKIGRVRVGAVMAPTPGLLADV
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCEEEEEEEECCCCHHHHHH
IRQLNRDHPRLEVAVHVETSDVLMPQLERDQLDIVLGRVPDGWDSSGLDFEQLGDEGLAI
HHHHCCCCCCEEEEEEEECCHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHCCCCCEEE
VVGPQHPLARRRKLSFEELTGYPWIMQPRPSPMRALIDRSFEDAGVPAPPSTIETAAVLM
EECCCCCHHHHHCCCHHHHCCCCEEECCCCCHHHHHHHCCHHHCCCCCCCHHHHHHHHHH
TTSLLADSELIAVLPESVAAYYGRLGALAVLPLPLPRKLGPYGIVTRRGRPPTASMSLLI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCCCHHHHHHHH
DALRALSR
HHHHHHCC
>Mature Secondary Structure
MIPPVSTLHGRLKMQHLRLLLAVEERGSLRQAAEALTLTQPAVSKMLQDMEDLLGVPLFE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHH
RHARGLRPTRFGLAATRYARLVFADMGGLRDELVALESGKIGRVRVGAVMAPTPGLLADV
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCEEEEEEEECCCCHHHHHH
IRQLNRDHPRLEVAVHVETSDVLMPQLERDQLDIVLGRVPDGWDSSGLDFEQLGDEGLAI
HHHHCCCCCCEEEEEEEECCHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHCCCCCEEE
VVGPQHPLARRRKLSFEELTGYPWIMQPRPSPMRALIDRSFEDAGVPAPPSTIETAAVLM
EECCCCCHHHHHCCCHHHHCCCCEEECCCCCHHHHHHHCCHHHCCCCCCCHHHHHHHHHH
TTSLLADSELIAVLPESVAAYYGRLGALAVLPLPLPRKLGPYGIVTRRGRPPTASMSLLI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCCCHHHHHHHH
DALRALSR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]