| Definition | Ralstonia eutropha H16 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008314 |
| Length | 2,912,490 |
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The map label for this gene is phbB [H]
Identifier: 116694156
GI number: 116694156
Start: 227169
End: 227900
Strand: Direct
Name: phbB [H]
Synonym: H16_B0201
Alternate gene names: 116694156
Gene position: 227169-227900 (Clockwise)
Preceding gene: 116694155
Following gene: 116694157
Centisome position: 7.8
GC content: 69.95
Gene sequence:
>732_bases ATGTCCCTTCCCGTAGCCACGCTCGTGACCGGCGGCAGTTCCGGTATCGGCCGCGCCATCTGTGAAATGCTGCTGGCCGA TGGCGTGACCCAGGTGGTCAATATCGACTATGCCGAACCGGCCTGGTCGCACCCGAACCTGACTTTCTTCCAGGCCGACC TGACCGATGCCGAGGCGACCCGCGCCGTGGCCGCGCAGGTGACCTCGCGCTTCGCCGTCACGCGCCTGGTGAACAACGCC GGCGCCACGCGCCCCGGCACCGCCGACACCGCCACCGTCGCCGACCTGGACTACGTGACCGCCCTGCACCTGCAGGCCAC GCTGCTGCTGACGCAGGCGTGCCTGCCCGCGATGCGTGCCGCCGGCTTTGGCCGCATCGTCAACATGGCCTCGCGCGCCG CGCTGGGCAAGGCCGAGCGCGTGGTGTACTCCGCCACCAAGGCCGGCCTGATCGGCATGACCCGCACGCTCGCGATGGAG CTGGGCGGCGACGGCGTCACTGTCAACGCCGTGGCCCCGGGCCCGATCGCCACCGAGCTGTTCCGCAAGAGCAACCCCGA AGGCGCCGAACAGACCCGGCGCATCCTGGCCAGCATCACGGTCAAGCGCATGGGTACGCCGGAAGACGTTGCGCGTGCCG CGCTGTTCTTCCTGTCGCCAGACAACGGCTTCGTCACCGGCCAGGTGCTGTACGTGTGCGGCGGCACCACGCTGGGCGTT GCGCCGGTGTAA
Upstream 100 bases:
>100_bases GCGGGTCTAAGTCAAGCCAGTTGGAAAGCTGAGGGTGTACTCCCTCTCCCGCAAGCGGGAGAGGGAGCGAGTTAGCGGTA GTTCTTGGAGTGAGCAAGAG
Downstream 100 bases:
>100_bases GCAGCGCGCGTCCCAGGCATCCGCATTCAAGCATTCAACAAGAAGAGACGTTAACCAAGCGTCACGCATGGCGGCCCGTG GCCGGGCCGCCCACCGGATG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 243; Mature: 242
Protein sequence:
>243_residues MSLPVATLVTGGSSGIGRAICEMLLADGVTQVVNIDYAEPAWSHPNLTFFQADLTDAEATRAVAAQVTSRFAVTRLVNNA GATRPGTADTATVADLDYVTALHLQATLLLTQACLPAMRAAGFGRIVNMASRAALGKAERVVYSATKAGLIGMTRTLAME LGGDGVTVNAVAPGPIATELFRKSNPEGAEQTRRILASITVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV APV
Sequences:
>Translated_243_residues MSLPVATLVTGGSSGIGRAICEMLLADGVTQVVNIDYAEPAWSHPNLTFFQADLTDAEATRAVAAQVTSRFAVTRLVNNA GATRPGTADTATVADLDYVTALHLQATLLLTQACLPAMRAAGFGRIVNMASRAALGKAERVVYSATKAGLIGMTRTLAME LGGDGVTVNAVAPGPIATELFRKSNPEGAEQTRRILASITVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV APV >Mature_242_residues SLPVATLVTGGSSGIGRAICEMLLADGVTQVVNIDYAEPAWSHPNLTFFQADLTDAEATRAVAAQVTSRFAVTRLVNNAG ATRPGTADTATVADLDYVTALHLQATLLLTQACLPAMRAAGFGRIVNMASRAALGKAERVVYSATKAGLIGMTRTLAMEL GGDGVTVNAVAPGPIATELFRKSNPEGAEQTRRILASITVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGVA PV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=35.2226720647773, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.0645161290323, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=32.0833333333333, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI59889578, Length=201, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI66933014, Length=203, Percent_Identity=30.5418719211823, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.1746031746032, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=29.7520661157025, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=29.3650793650794, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI7705925, Length=236, Percent_Identity=31.3559322033898, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=31.1224489795918, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=33.0543933054393, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=32.2448979591837, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=30.3643724696356, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1789208, Length=238, Percent_Identity=30.2521008403361, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=7e-19, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.1475409836066, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI2367365, Length=230, Percent_Identity=30.8695652173913, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=28.6290322580645, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=27.5720164609054, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=26.2548262548263, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1786812, Length=246, Percent_Identity=30.0813008130081, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=28.2786885245902, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=31.5573770491803, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17561402, Length=243, Percent_Identity=28.8065843621399, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.2788844621514, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.4354838709677, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=31.6455696202532, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=31.1740890688259, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.1526717557252, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=30.1960784313725, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=30.2681992337165, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=28.957528957529, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=26.8482490272374, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=29.296875, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=26.4591439688716, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=29.296875, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=29.5719844357977, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=27.6264591439689, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=164, Percent_Identity=32.3170731707317, Blast_Score=69, Evalue=7e-13, Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=32.9166666666667, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=28.6307053941909, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI23397609, Length=237, Percent_Identity=32.0675105485232, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=29.4605809128631, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=30.327868852459, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI28571526, Length=242, Percent_Identity=29.3388429752066, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=30.0411522633745, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24644337, Length=195, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=239, Percent_Identity=28.4518828451883, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24665247, Length=239, Percent_Identity=28.4518828451883, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 25167; Mature: 25036
Theoretical pI: Translated: 7.35; Mature: 7.35
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLPVATLVTGGSSGIGRAICEMLLADGVTQVVNIDYAEPAWSHPNLTFFQADLTDAEAT CCCCCEEEEECCCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCEEEEEECCCCHHHH RAVAAQVTSRFAVTRLVNNAGATRPGTADTATVADLDYVTALHLQATLLLTQACLPAMRA HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGFGRIVNMASRAALGKAERVVYSATKAGLIGMTRTLAMELGGDGVTVNAVAPGPIATEL CCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHEECCCCEEEEEECCCHHHHHH FRKSNPEGAEQTRRILASITVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV HHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCCCEEEEEEEEEECCCEECC APV CCC >Mature Secondary Structure SLPVATLVTGGSSGIGRAICEMLLADGVTQVVNIDYAEPAWSHPNLTFFQADLTDAEAT CCCCEEEEECCCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCEEEEEECCCCHHHH RAVAAQVTSRFAVTRLVNNAGATRPGTADTATVADLDYVTALHLQATLLLTQACLPAMRA HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGFGRIVNMASRAALGKAERVVYSATKAGLIGMTRTLAMELGGDGVTVNAVAPGPIATEL CCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHEECCCCEEEEEECCCHHHHHH FRKSNPEGAEQTRRILASITVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV HHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCCCEEEEEEEEEECCCEECC APV CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7582015; 11481430 [H]