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The map label for this gene is acoR

Identifier: 116694102

GI number: 116694102

Start: 164717

End: 166723

Strand: Direct

Name: acoR

Synonym: H16_B0142

Alternate gene names: 116694102

Gene position: 164717-166723 (Clockwise)

Preceding gene: 116694101

Following gene: 116694103

Centisome position: 5.66

GC content: 70.95

Gene sequence:

>2007_bases
ATGGACCTGCGGCAACGCGAGCACATCGAGACGGTGGTCCAGGCCACCACATACCTTGCCCCGCCGGCCGTGCTTGCGGA
CCGGATCGCGCACGACGCCATCATCCAGAACTCATGGCGCCGCTGCGTGCACCAGTACGGCCTGGATCCGTCGCGCATGC
AGGAGGCGCGCATCCTGCCGCAGCCGCGCCTGCGCGAACACCAGGAACGCATCGACGACTTCGCGCGCATCGCGCGCCAC
GGCCTGCAGAGCCTGTATGGGCAAGTGGCGGGCCTGGGCTATGTGGTGCTGCTGACCGATGCGCAGGGCGTGACCGTCGA
CTATATCGGCGAGGCCCGCAGCGATGCCGCGCTGCGCCACGCGGGCCTGTACCTGGGCGCCGAGTGGAGCGAGAGCGGCG
CCGGCACCTGCGCGGTCGGCACCGCCCTGGCCACGGGCCAGGCGCTGACGGTGCACCAGGCCGACCATTTCGACGCCACC
CATATCCCACTGACCTGCACCGCCGCGCCGCTGTTCGACACGCACGGCAACCTGCACGCCATCCTCGACATCTCCGCGCT
GACCTCGCCGCAGGCCAAGGACAGCCAGGGGCTGGCGCTGCAGATGGTGCGCATCTACGCCGCGCATATCGAGAACGCCA
ACTTCCTGCGCGCGCACCGCCGCGACTGGATCCTGAAGCTGAACGTGGCGCCGGAGTTCGTCGACGTCAATCCCGAATAC
CTGCTGGCGCTGGACGAGGCGGGCCGCATCGTCGGCCATAACCACCGCGCCAGGCTGATGCTGGAAGGCGAGCTGGGTGG
CGCACCGGGCGCCACCGTGCTGGGCCAGCGGTTCGAGACGCTGTTCGACGCGCGCCTGGAGGACCTGGGCCACTATGTCT
ATTCGCGCCCGAGCGAGCAGCGCCTGGTGGCGCTGACCCGCAGTGGCGGCCTGCTGTACCTGAGCGTGCTGCCGCCCGCG
CTGCGCTGGCAGGCGCCGCCCGCCGAAACGCAGGTGGCGATGCCGGATGCCCTGGCGGCGCTGACCGGCGGCGATGCCGC
GCTGCAGCTGCAGTTGCAGCGCGCGGCGCGCCTGGTCGATTCGCCGATCAACCTGCTGATCCACGGCGAGACCGGCAGCG
GCAAGGAGTTCCTGGCCAAGGCGCTGCATCTTGCCAGCGCGCGCCGCGGCGGGCCGTTCGTAGCGGTGAACTGCGCGGCG
ATCCCTGAAACACTGATTGAAAGCGAATTGTTCGGGCACCTGCCCAACAGCTTCTCCGGCGCAGGCCCGCGCGGCAAGCG
CGGCCTGATCCAGGAGGCCGACGGCGGCACGCTGTTCCTGGACGAGATCGGCGACATGCCGCGCGAGCTGCAGTCGCGGC
TGCTGCGCGTGCTGGCCGAGGGCGAAGTGCTGCCTGTTGGCGCCGCGCGGCCGGTGCCGGTGCGGCTGCGGGTCATTTCC
GCCACGCACCACAGCCTGGAGCAACTGGTGGCCGACGGGCGCTTCCGCGAGGACCTGTACTACCGCCTCAACGGCGCGCG
CTTTACGCTGCCGCCGCTGCGTGCGCGTACCGACCTGGACTGGCTGGTCCGCAAGCTGCTGCAGGAAGGGAGCGCAGAGG
GCAGCGAGATCACGCTGTCGCCCGCGGCACGCGAGCGGCTGCACCGCCACCGCTGGCCTGGCAACCTGCGCGAACTGCGC
AACGTGCTGGAGTACGCGCGCGCGGTCTGCGCCGACGGCTATATCGATGTGCCGGACCTGCCTGACAGCCTGGCGGGACC
CGCACCGTCCGCCGCCCTGCCGCAGCCAGGGCCCGCCCAGTCACCCGCTGCCGCACCGTTCGACCCGCACCAGTTGCCGC
CGGAAGGCATGCTGCTGATGCAATACCTGCGCGCGTCCGGCTGGAACCTGAGCGCCGTGGCGCGGCAGATCGGCGTCAGC
CGCATGACGCTGTACCGGCGCATGGAGCGCTACGGCATCCAGTCGCCCAACCGGCGCGACGGCGGCCCGGAGCCCACCGA
CGCATAA

Upstream 100 bases:

>100_bases
CGAGAGAGGCGCGGCTCCCGCAGCACGCGCCCGACAGTTCGCACGATCCACCGCCCCATCCGAAACATGGGGCCGACGGC
AGCGACGACAGGAGACAGCG

Downstream 100 bases:

>100_bases
GCCGGCAGGCAGCACGGCGCACGCGCGCCGTCTGTGCGATACGGTTGTCCATCCCCTGTACACCTGCGCTGTGACACCTG
TCACAGCGCAGCGTTGTTTT

Product: acetoin catabolism transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MDLRQREHIETVVQATTYLAPPAVLADRIAHDAIIQNSWRRCVHQYGLDPSRMQEARILPQPRLREHQERIDDFARIARH
GLQSLYGQVAGLGYVVLLTDAQGVTVDYIGEARSDAALRHAGLYLGAEWSESGAGTCAVGTALATGQALTVHQADHFDAT
HIPLTCTAAPLFDTHGNLHAILDISALTSPQAKDSQGLALQMVRIYAAHIENANFLRAHRRDWILKLNVAPEFVDVNPEY
LLALDEAGRIVGHNHRARLMLEGELGGAPGATVLGQRFETLFDARLEDLGHYVYSRPSEQRLVALTRSGGLLYLSVLPPA
LRWQAPPAETQVAMPDALAALTGGDAALQLQLQRAARLVDSPINLLIHGETGSGKEFLAKALHLASARRGGPFVAVNCAA
IPETLIESELFGHLPNSFSGAGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPVGAARPVPVRLRVIS
ATHHSLEQLVADGRFREDLYYRLNGARFTLPPLRARTDLDWLVRKLLQEGSAEGSEITLSPAARERLHRHRWPGNLRELR
NVLEYARAVCADGYIDVPDLPDSLAGPAPSAALPQPGPAQSPAAAPFDPHQLPPEGMLLMQYLRASGWNLSAVARQIGVS
RMTLYRRMERYGIQSPNRRDGGPEPTDA

Sequences:

>Translated_668_residues
MDLRQREHIETVVQATTYLAPPAVLADRIAHDAIIQNSWRRCVHQYGLDPSRMQEARILPQPRLREHQERIDDFARIARH
GLQSLYGQVAGLGYVVLLTDAQGVTVDYIGEARSDAALRHAGLYLGAEWSESGAGTCAVGTALATGQALTVHQADHFDAT
HIPLTCTAAPLFDTHGNLHAILDISALTSPQAKDSQGLALQMVRIYAAHIENANFLRAHRRDWILKLNVAPEFVDVNPEY
LLALDEAGRIVGHNHRARLMLEGELGGAPGATVLGQRFETLFDARLEDLGHYVYSRPSEQRLVALTRSGGLLYLSVLPPA
LRWQAPPAETQVAMPDALAALTGGDAALQLQLQRAARLVDSPINLLIHGETGSGKEFLAKALHLASARRGGPFVAVNCAA
IPETLIESELFGHLPNSFSGAGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPVGAARPVPVRLRVIS
ATHHSLEQLVADGRFREDLYYRLNGARFTLPPLRARTDLDWLVRKLLQEGSAEGSEITLSPAARERLHRHRWPGNLRELR
NVLEYARAVCADGYIDVPDLPDSLAGPAPSAALPQPGPAQSPAAAPFDPHQLPPEGMLLMQYLRASGWNLSAVARQIGVS
RMTLYRRMERYGIQSPNRRDGGPEPTDA
>Mature_668_residues
MDLRQREHIETVVQATTYLAPPAVLADRIAHDAIIQNSWRRCVHQYGLDPSRMQEARILPQPRLREHQERIDDFARIARH
GLQSLYGQVAGLGYVVLLTDAQGVTVDYIGEARSDAALRHAGLYLGAEWSESGAGTCAVGTALATGQALTVHQADHFDAT
HIPLTCTAAPLFDTHGNLHAILDISALTSPQAKDSQGLALQMVRIYAAHIENANFLRAHRRDWILKLNVAPEFVDVNPEY
LLALDEAGRIVGHNHRARLMLEGELGGAPGATVLGQRFETLFDARLEDLGHYVYSRPSEQRLVALTRSGGLLYLSVLPPA
LRWQAPPAETQVAMPDALAALTGGDAALQLQLQRAARLVDSPINLLIHGETGSGKEFLAKALHLASARRGGPFVAVNCAA
IPETLIESELFGHLPNSFSGAGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPVGAARPVPVRLRVIS
ATHHSLEQLVADGRFREDLYYRLNGARFTLPPLRARTDLDWLVRKLLQEGSAEGSEITLSPAARERLHRHRWPGNLRELR
NVLEYARAVCADGYIDVPDLPDSLAGPAPSAALPQPGPAQSPAAAPFDPHQLPPEGMLLMQYLRASGWNLSAVARQIGVS
RMTLYRRMERYGIQSPNRRDGGPEPTDA

Specific function: Required for sigma-54-dependent transcription of acoXABC

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain

Homologues:

Organism=Escherichia coli, GI1789233, Length=315, Percent_Identity=42.5396825396825, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1790299, Length=348, Percent_Identity=41.3793103448276, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1788550, Length=316, Percent_Identity=39.2405063291139, Blast_Score=215, Evalue=7e-57,
Organism=Escherichia coli, GI1788905, Length=317, Percent_Identity=39.7476340694006, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1790437, Length=314, Percent_Identity=40.1273885350318, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082117, Length=402, Percent_Identity=35.5721393034826, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1786524, Length=301, Percent_Identity=43.8538205980066, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1789087, Length=319, Percent_Identity=38.2445141065831, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI87082152, Length=313, Percent_Identity=37.3801916932907, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI87081872, Length=292, Percent_Identity=39.041095890411, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1787583, Length=321, Percent_Identity=35.5140186915888, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI87081858, Length=658, Percent_Identity=23.7082066869301, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1789828, Length=324, Percent_Identity=34.2592592592593, Blast_Score=135, Evalue=9e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): ACOR_CUPNH (P28614)

Other databases:

- EMBL:   M90471
- EMBL:   AM260480
- PIR:   A42890
- RefSeq:   YP_728313.1
- ProteinModelPortal:   P28614
- SMR:   P28614
- STRING:   P28614
- GeneID:   4454947
- GenomeReviews:   AM260480_GR
- KEGG:   reh:H16_B0142
- eggNOG:   COG3284
- HOGENOM:   HBG740884
- OMA:   PDYLLAW
- ProtClustDB:   CLSK939213
- BioCyc:   REUT381666:H16_B0142-MONOMER
- GO:   GO:0005622
- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- PRINTS:   PR01590
- SMART:   SM00382

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 72963; Mature: 72963

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00675 SIGMA54_INTERACT_1; PS00676 SIGMA54_INTERACT_2; PS00688 SIGMA54_INTERACT_3; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRQREHIETVVQATTYLAPPAVLADRIAHDAIIQNSWRRCVHQYGLDPSRMQEARILP
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
QPRLREHQERIDDFARIARHGLQSLYGQVAGLGYVVLLTDAQGVTVDYIGEARSDAALRH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEECCCCCHHHHHHH
AGLYLGAEWSESGAGTCAVGTALATGQALTVHQADHFDATHIPLTCTAAPLFDTHGNLHA
CCEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCEEE
ILDISALTSPQAKDSQGLALQMVRIYAAHIENANFLRAHRRDWILKLNVAPEFVDVNPEY
EEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCEEECCCCE
LLALDEAGRIVGHNHRARLMLEGELGGAPGATVLGQRFETLFDARLEDLGHYVYSRPSEQ
EEEECCCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLVALTRSGGLLYLSVLPPALRWQAPPAETQVAMPDALAALTGGDAALQLQLQRAARLVD
EEEEEECCCCEEEEEECCHHHHCCCCCCCCEECCCHHHHHHCCCCHHEEHHHHHHHHHHC
SPINLLIHGETGSGKEFLAKALHLASARRGGPFVAVNCAAIPETLIESELFGHLPNSFSG
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCC
AGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPVGAARPVPVRLRVIS
CCCCCCCCCCEECCCCEEEHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEE
ATHHSLEQLVADGRFREDLYYRLNGARFTLPPLRARTDLDWLVRKLLQEGSAEGSEITLS
HHHHHHHHHHHCCCHHHCHHEEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEC
PAARERLHRHRWPGNLRELRNVLEYARAVCADGYIDVPDLPDSLAGPAPSAALPQPGPAQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
SPAAAPFDPHQLPPEGMLLMQYLRASGWNLSAVARQIGVSRMTLYRRMERYGIQSPNRRD
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GGPEPTDA
CCCCCCCC
>Mature Secondary Structure
MDLRQREHIETVVQATTYLAPPAVLADRIAHDAIIQNSWRRCVHQYGLDPSRMQEARILP
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
QPRLREHQERIDDFARIARHGLQSLYGQVAGLGYVVLLTDAQGVTVDYIGEARSDAALRH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEECCCCCHHHHHHH
AGLYLGAEWSESGAGTCAVGTALATGQALTVHQADHFDATHIPLTCTAAPLFDTHGNLHA
CCEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCEEE
ILDISALTSPQAKDSQGLALQMVRIYAAHIENANFLRAHRRDWILKLNVAPEFVDVNPEY
EEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCEEECCCCE
LLALDEAGRIVGHNHRARLMLEGELGGAPGATVLGQRFETLFDARLEDLGHYVYSRPSEQ
EEEECCCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLVALTRSGGLLYLSVLPPALRWQAPPAETQVAMPDALAALTGGDAALQLQLQRAARLVD
EEEEEECCCCEEEEEECCHHHHCCCCCCCCEECCCHHHHHHCCCCHHEEHHHHHHHHHHC
SPINLLIHGETGSGKEFLAKALHLASARRGGPFVAVNCAAIPETLIESELFGHLPNSFSG
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCC
AGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPVGAARPVPVRLRVIS
CCCCCCCCCCEECCCCEEEHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEE
ATHHSLEQLVADGRFREDLYYRLNGARFTLPPLRARTDLDWLVRKLLQEGSAEGSEITLS
HHHHHHHHHHHCCCHHHCHHEEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEC
PAARERLHRHRWPGNLRELRNVLEYARAVCADGYIDVPDLPDSLAGPAPSAALPQPGPAQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
SPAAAPFDPHQLPPEGMLLMQYLRASGWNLSAVARQIGVSRMTLYRRMERYGIQSPNRRD
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GGPEPTDA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052