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The map label for this gene is amn [H]

Identifier: 116694030

GI number: 116694030

Start: 78566

End: 80053

Strand: Direct

Name: amn [H]

Synonym: H16_B0070

Alternate gene names: 116694030

Gene position: 78566-80053 (Clockwise)

Preceding gene: 116694028

Following gene: 116694038

Centisome position: 2.7

GC content: 67.47

Gene sequence:

>1488_bases
ATGGCCTCCATGAACGCCCCCGTCTTTTCCTCCGCACATCCGGCCGATCAGCTTGCCGAGTTCACCGACGCGGATGCGGC
GATCGCGCGCATCCGCGACATCTACGAAGCTTCTGTCGGCGCCGTGCGCGCGCGCTTCGATGCCTTCGCCAGCGGCAAGC
CGCTGCCCTCGGCCGCGCATGCGTGCTATCCGTACCTGGGCATCTCGGTCAATATCGAGACCATGGTCACCGACAGCCGG
CCGTCATGGGGCACGGTGGCCTACCCGGGCGTGTATGGCACCACCGTGACCCGCCCCGACCTGCTGGCGGACTACTACCG
CGACCAGATCGAGCGGCTGATGCGCTATCACCGCGTGCCTGTGGTGGTAGGGCTGAGCCGGCGCCCGATCCCGCTGCCGT
TCGTGATCGAGGCTTCGACCACCGACATCAGCTACACCCAGGCGCGCGAGCTGGAGGCATCGTTCGTGCTGCCCGAGCTG
AGCCGCATCGACGACGGCATCGCCAATGGCACCTATGAGCCGATCCCGGGCGAGGCCTGGCCGCTGTCGCTGTTCCCGGC
CGAGCGCGTGGACCTGGCCCTGCAGCGGCTGTACCACTACACCGGCACGGCACCGCAGCATTTCCAGCGCTTCGTGCTGT
TCACCAACTACCAGCGCTATGTCGACGAGTTTGTCGAGCTGGGCCGGGGCCTGATGGCCAGCAGCGACGGCGGCGGCTAC
ACCCGCTTTGTCGAACCCGGCGACGTGATGCAGGAACTGGGCGGCGCGGAACCCGACGACGCCTCGCGCCCGCGCGCGCT
GCCGCAGATGCCGGCCTATCACCTGGTGCGCGAAGACAAGCTGGGGGTGACGCTGGTCAATATCGGCGTGGGACCGTCCA
ACGCCAAGACCATGACCGACCACCTGGCCGTGCTGCGCCCGCATTGCTGGCTGATGGTGGGCCACTGCGGCGGCTTGCGC
CGCTCGCAGCAGCTCGGCGACTACGTGCTGGCGCACGCCTATGTGCGCGACGACCACGTGCTCGACCACGACTTGCCGCC
GTGGGTGCCGGTGCCGCCAATCGCCGAGATCCAGGTGGCCTTGCAGGAGGCCGTTGCGCGCGTGACCGGGCTGTCCGGCA
ACGAGATGAAGACCCGCATGCGCACCGGCACGGTGGTCTCGACCGACGACCGCAACTGGGAACTCAAGTCCAAGTCGCTG
TATGCGCGCTTCAACCAGTCGCGCGCGATTGCCATCGATATGGAAAGCGCGGCGGTGGCGGCCAACGGCTTCCGGCTGCG
CGTGCCCTATGGCACCTTGCTATGCGTGTCGGACAAGCCGCTGCATGGCGAGCTCAAGCTGCGCGGCATGGCCAACGCCT
TCTATCGCCAGCGTGTCAGCCAGCATATGACCATCGGGCTGGAGGCGATCCGCATCCTGCGTGAGAACGGGGTGGAGCAG
CTGCATTCGCGCAAGCTGCGCAGTTTCGACGAGCCGGCGTTCCGCTAG

Upstream 100 bases:

>100_bases
TGCCGCGCAATTGGCGGAGTGTAGCGAGCGGGCGCGGGCGCGTCAATTTGGCTTCCGGCGGGGTCGGGTGCTGCTCACGC
CGGCGCGCCGGCGCGGTATC

Downstream 100 bases:

>100_bases
TCGCCCCGCTCCCGGCAGCCGCAAAAGGCAACTTCCGCTCAGTGGCTGATCATCCAGGGCCGCCCCCCGGGGGCCTTGGC
CGCGTCCGTGCGCCCGGCCA

Product: AMP nucleosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MASMNAPVFSSAHPADQLAEFTDADAAIARIRDIYEASVGAVRARFDAFASGKPLPSAAHACYPYLGISVNIETMVTDSR
PSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVPVVVGLSRRPIPLPFVIEASTTDISYTQARELEASFVLPEL
SRIDDGIANGTYEPIPGEAWPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFVELGRGLMASSDGGGY
TRFVEPGDVMQELGGAEPDDASRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTDHLAVLRPHCWLMVGHCGGLR
RSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVALQEAVARVTGLSGNEMKTRMRTGTVVSTDDRNWELKSKSL
YARFNQSRAIAIDMESAAVAANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAIRILRENGVEQ
LHSRKLRSFDEPAFR

Sequences:

>Translated_495_residues
MASMNAPVFSSAHPADQLAEFTDADAAIARIRDIYEASVGAVRARFDAFASGKPLPSAAHACYPYLGISVNIETMVTDSR
PSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVPVVVGLSRRPIPLPFVIEASTTDISYTQARELEASFVLPEL
SRIDDGIANGTYEPIPGEAWPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFVELGRGLMASSDGGGY
TRFVEPGDVMQELGGAEPDDASRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTDHLAVLRPHCWLMVGHCGGLR
RSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVALQEAVARVTGLSGNEMKTRMRTGTVVSTDDRNWELKSKSL
YARFNQSRAIAIDMESAAVAANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAIRILRENGVEQ
LHSRKLRSFDEPAFR
>Mature_494_residues
ASMNAPVFSSAHPADQLAEFTDADAAIARIRDIYEASVGAVRARFDAFASGKPLPSAAHACYPYLGISVNIETMVTDSRP
SWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVPVVVGLSRRPIPLPFVIEASTTDISYTQARELEASFVLPELS
RIDDGIANGTYEPIPGEAWPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFVELGRGLMASSDGGGYT
RFVEPGDVMQELGGAEPDDASRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTDHLAVLRPHCWLMVGHCGGLRR
SQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVALQEAVARVTGLSGNEMKTRMRTGTVVSTDDRNWELKSKSLY
ARFNQSRAIAIDMESAAVAANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAIRILRENGVEQL
HSRKLRSFDEPAFR

Specific function: Involved in regulation of AMP concentrations [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788293, Length=476, Percent_Identity=49.7899159663866, Blast_Score=434, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011271
- InterPro:   IPR018953
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF10423 AMNp_N; PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.4 [H]

Molecular weight: Translated: 55040; Mature: 54909

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASMNAPVFSSAHPADQLAEFTDADAAIARIRDIYEASVGAVRARFDAFASGKPLPSAAH
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ACYPYLGISVNIETMVTDSRPSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVP
HHHCEEEEEEEEEEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VVVGLSRRPIPLPFVIEASTTDISYTQARELEASFVLPELSRIDDGIANGTYEPIPGEAW
EEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHCCHHCCCCCCCCCCCCC
PLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFVELGRGLMASSDGGGY
EEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCE
TRFVEPGDVMQELGGAEPDDASRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTD
EEEECCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHH
HLAVLRPHCWLMVGHCGGLRRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVA
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
LQEAVARVTGLSGNEMKTRMRTGTVVSTDDRNWELKSKSLYARFNQSRAIAIDMESAAVA
HHHHHHHHHCCCCCHHHHHHHCCCEEECCCCCCEECCHHHHHEECCCCEEEEEECCCEEE
ANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAIRILRENGVEQ
ECCEEEEECCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHSRKLRSFDEPAFR
HHHHHHHCCCCCCCC
>Mature Secondary Structure 
ASMNAPVFSSAHPADQLAEFTDADAAIARIRDIYEASVGAVRARFDAFASGKPLPSAAH
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ACYPYLGISVNIETMVTDSRPSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVP
HHHCEEEEEEEEEEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VVVGLSRRPIPLPFVIEASTTDISYTQARELEASFVLPELSRIDDGIANGTYEPIPGEAW
EEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHCCHHCCCCCCCCCCCCC
PLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFVELGRGLMASSDGGGY
EEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCE
TRFVEPGDVMQELGGAEPDDASRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTD
EEEECCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHH
HLAVLRPHCWLMVGHCGGLRRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVA
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
LQEAVARVTGLSGNEMKTRMRTGTVVSTDDRNWELKSKSLYARFNQSRAIAIDMESAAVA
HHHHHHHHHCCCCCHHHHHHHCCCEEECCCCCCEECCHHHHHEECCCCEEEEEECCCEEE
ANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAIRILRENGVEQ
ECCEEEEECCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHSRKLRSFDEPAFR
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]