Click here to switch to the map view.

The map label for this gene is epsB [H]

Identifier: 116693972

GI number: 116693972

Start: 11889

End: 14327

Strand: Direct

Name: epsB [H]

Synonym: H16_B0012

Alternate gene names: 116693972

Gene position: 11889-14327 (Clockwise)

Preceding gene: 116693971

Following gene: 116693973

Centisome position: 0.41

GC content: 71.3

Gene sequence:

>2439_bases
GTGAGCAGACTGTCATATGCCGGTGGCCCGGCTGAGAGCGCCACCCCGCGCCGTGAGGCCCAGCCGGGCGTCACGCAGGC
GCGCGCGCTGATGGACCACCTCGGCTGGATTGCCGCGGCTGGCGTGGCCGGTGCGGCCGCAGGCTTGCTGGTGGCGCTGT
CGGCGCCGCCGCAGTATCGCGCGCAGGCGCTGGTGCAGGTTGAGGGGCGCGATGGCGGCATGCGCAGCGTCGCCCAGATG
CAGGGCCCGGCGGCCTTCGACGCAGGCCTGCTCAAGAGCCGCGCCGTGGTCGGTCCGGTGGTGGAGCGGCTGCGGCTCGA
TATCACCGCGCAGCCGCTGCGTGCGCCGCTGCTGGGCGCGCTGGTCCAGCGCTTTTCCACACCCGGCCAGCCGCGCGGCA
CCTGGCCTGCCAGCCTGGGCTATGCCTGGGGCGGCGAGCGTCTGGTAATCGCCAGCATGACCGTGCCCGAGGCGCTGGTA
GACCAGCCACTCACCTTCGAGGTGCGCAGCGACGGCCGCTACCGCCTGATGCAGCAGGACACCTTGCTGCTGGAAGGGCG
GGCCGGCGAGACTGCGATGGCCAACGGCATTGTGCTGCGCGTGGACAAGATCGAGGCCGGGCCCGGTACGCGCTTCCAGC
TCACGCGGCACGACCTGGCCCGCACCGCCGAGTCCGTGCGCCGCGGGCTCACGGTGGAAAGCGAACGCAGTGAAACCCCG
GCGAGCCTGGGCGGCGCGGCCGACCCCCTGACCGCGCCGGGCGGCACCGTGCGCGTGAGCTGGCAATACCCGGACCGCCA
GCTTGCCGCCCAACTCGTCAACGGGGTCACGCGCGCCTATATCGACGGCCAGACCGACAAGCGCCGCCAGGACGCGGCCG
GCACGCTCGCGTTCCTCTCGGGCGAGCTGCCGCGCGTGCAGAGCGAACTCACGCGCGCCGAAGAGGCGCTCACGCGCTAC
CGCGCGCGCACGGGTTCGCTGCAGCCCAGCCGCGACGCGCAGTCGTTCCTCAGCAACAGCATGGAGTACCAGCGCCAGAT
CGCAGCGCTCAAGCTTGAGCGCACGCGGCTGCTCCAGCGCTTCACGCCCGAGGCCAACGAGGTCCGCACCGTCGACAGCC
AGATCCAGCAGATGACTCGCGAGCGCGCGGAGATCGACGCGCGTATGCAGACCCTGTCGGCCTCCGAGCGCGAATCGGTG
GCGCTCACGCGTGACGTCAAGGTGGCCGAGGACATGTACATGTCCTTGCGCAGCAAGGTCGAGCAGCTGTCGCTGATGCT
GTCCGACAGCTCTACCCAGATGCGCGTGGTCGATGCCGCGATCGCGCCGGTCACACCGGTCGGTCTCGGCGCGTGGCCGT
TCGCCTCCGCCGGCGCCTTGCTCGGCCTGTGCCTGGGCGTGGCCGCGATCAACCTGCGCCAGCGCATGCGCCCGTCGGTG
GCCAGCGCCGCCGATGCGGAACAGCGCCTGGGCATGGCCATGCTGGGCGATATCGCCTTCAGCAACGAGCAGACCGAGCT
GGAACGGCTGGTCGAAGCCAAGCGCCGCCTGGGCATCGCTTCCGGCTTTGTGCTGCCGCCCAATGTGCGCCTCGGCCGGC
CGGAGTCTGTCACCAGCGTGATCGACGCCGCCACGGCCGCCGCGCCCGAGGACGAACGCGCGCGCGCCGAACGGCTGCTG
CGCCAGGGCCTGCACGACCAGTTCCTGCTGGCGCGGCGCGCCCCGCATTCGCTTGCCGTGGAAGGCCTGCGCACGCTGCG
GGCGGCGCTGCATTTCGCGTTGCGCGATGCACCCAACTGCGTGGTTGCGGTGACCAGCCCCGCCGCCAGCGCCGGCAAGA
CCTTCGCCGCGGTTAACCTCGCGGTGCTGTTCGCCGAAGCCGGCCAGCGCGTGCTGCTGGTCGACGCCGACCTGCGCCGC
GGCCGCGTGGCGGACTGGTTCGACCTGCCTGCCGAGCCCGGGCTGGCAGAAGTGCTCGCTGGCCGCAGCGCGATCGCCGA
AGCGGTCAAGCCGAGCGTGGTCAATGGCCTGTTCCTGCTCAGCCGCGGCGCGGTGCCGGCCAATCCGTCCGAGCTGCTGA
TGCTGCCCGCGCTGGCGGAATCCCTGCGGCTGTGCGCGGGGCGCTTCGACCTGGTGCTGGTGGACACGCCGCCGGTGATG
GCGGTGGCCGATGCCACGCTGGTGGCCAACTTGGCGGGTTCCACGCTGGTGGTGGTGCGCGCCGATGTCACGGCGACGGC
GCAGGTCGATGAAACCCTCAAGCGCCTGGCGCACGCCAATGCCAGGCTGGCCGGTGGCATCCTCAACGGTGTCATGCCCC
GGCGCAGCAACCGGGCGGACTTCAATACCATCAATCCTTATCTGGGGATGCCGTTGCCACGAGCGGTAGCGAAGCCTCCC
GCATTGGCCGGTCAAGCCGATCGGGTAGGGAAAAACTGA

Upstream 100 bases:

>100_bases
GCCCGCGCTGGCCAGCGCCTGAGCGGCACGCTTCGGCGCGTGTGGCCTGCGAAGCGCGGCGTGTATACGCCGCGCCGATC
CCATTTGAGGAGCTGTAGTC

Downstream 100 bases:

>100_bases
CGCATGCCAAAGCACGCCAGAAACCGCACCGCCATTTGTGTGGGTGTACCTGTTTCTGCGAGCGTTTGGCGGACGTTCTG
AGCACACGCATTGGTGTGAA

Product: EPS I polysaccharide export protein, putative tyrosine-protein kinase

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: EPS I polysaccharide export protein epsB [H]

Number of amino acids: Translated: 812; Mature: 811

Protein sequence:

>812_residues
MSRLSYAGGPAESATPRREAQPGVTQARALMDHLGWIAAAGVAGAAAGLLVALSAPPQYRAQALVQVEGRDGGMRSVAQM
QGPAAFDAGLLKSRAVVGPVVERLRLDITAQPLRAPLLGALVQRFSTPGQPRGTWPASLGYAWGGERLVIASMTVPEALV
DQPLTFEVRSDGRYRLMQQDTLLLEGRAGETAMANGIVLRVDKIEAGPGTRFQLTRHDLARTAESVRRGLTVESERSETP
ASLGGAADPLTAPGGTVRVSWQYPDRQLAAQLVNGVTRAYIDGQTDKRRQDAAGTLAFLSGELPRVQSELTRAEEALTRY
RARTGSLQPSRDAQSFLSNSMEYQRQIAALKLERTRLLQRFTPEANEVRTVDSQIQQMTRERAEIDARMQTLSASERESV
ALTRDVKVAEDMYMSLRSKVEQLSLMLSDSSTQMRVVDAAIAPVTPVGLGAWPFASAGALLGLCLGVAAINLRQRMRPSV
ASAADAEQRLGMAMLGDIAFSNEQTELERLVEAKRRLGIASGFVLPPNVRLGRPESVTSVIDAATAAAPEDERARAERLL
RQGLHDQFLLARRAPHSLAVEGLRTLRAALHFALRDAPNCVVAVTSPAASAGKTFAAVNLAVLFAEAGQRVLLVDADLRR
GRVADWFDLPAEPGLAEVLAGRSAIAEAVKPSVVNGLFLLSRGAVPANPSELLMLPALAESLRLCAGRFDLVLVDTPPVM
AVADATLVANLAGSTLVVVRADVTATAQVDETLKRLAHANARLAGGILNGVMPRRSNRADFNTINPYLGMPLPRAVAKPP
ALAGQADRVGKN

Sequences:

>Translated_812_residues
MSRLSYAGGPAESATPRREAQPGVTQARALMDHLGWIAAAGVAGAAAGLLVALSAPPQYRAQALVQVEGRDGGMRSVAQM
QGPAAFDAGLLKSRAVVGPVVERLRLDITAQPLRAPLLGALVQRFSTPGQPRGTWPASLGYAWGGERLVIASMTVPEALV
DQPLTFEVRSDGRYRLMQQDTLLLEGRAGETAMANGIVLRVDKIEAGPGTRFQLTRHDLARTAESVRRGLTVESERSETP
ASLGGAADPLTAPGGTVRVSWQYPDRQLAAQLVNGVTRAYIDGQTDKRRQDAAGTLAFLSGELPRVQSELTRAEEALTRY
RARTGSLQPSRDAQSFLSNSMEYQRQIAALKLERTRLLQRFTPEANEVRTVDSQIQQMTRERAEIDARMQTLSASERESV
ALTRDVKVAEDMYMSLRSKVEQLSLMLSDSSTQMRVVDAAIAPVTPVGLGAWPFASAGALLGLCLGVAAINLRQRMRPSV
ASAADAEQRLGMAMLGDIAFSNEQTELERLVEAKRRLGIASGFVLPPNVRLGRPESVTSVIDAATAAAPEDERARAERLL
RQGLHDQFLLARRAPHSLAVEGLRTLRAALHFALRDAPNCVVAVTSPAASAGKTFAAVNLAVLFAEAGQRVLLVDADLRR
GRVADWFDLPAEPGLAEVLAGRSAIAEAVKPSVVNGLFLLSRGAVPANPSELLMLPALAESLRLCAGRFDLVLVDTPPVM
AVADATLVANLAGSTLVVVRADVTATAQVDETLKRLAHANARLAGGILNGVMPRRSNRADFNTINPYLGMPLPRAVAKPP
ALAGQADRVGKN
>Mature_811_residues
SRLSYAGGPAESATPRREAQPGVTQARALMDHLGWIAAAGVAGAAAGLLVALSAPPQYRAQALVQVEGRDGGMRSVAQMQ
GPAAFDAGLLKSRAVVGPVVERLRLDITAQPLRAPLLGALVQRFSTPGQPRGTWPASLGYAWGGERLVIASMTVPEALVD
QPLTFEVRSDGRYRLMQQDTLLLEGRAGETAMANGIVLRVDKIEAGPGTRFQLTRHDLARTAESVRRGLTVESERSETPA
SLGGAADPLTAPGGTVRVSWQYPDRQLAAQLVNGVTRAYIDGQTDKRRQDAAGTLAFLSGELPRVQSELTRAEEALTRYR
ARTGSLQPSRDAQSFLSNSMEYQRQIAALKLERTRLLQRFTPEANEVRTVDSQIQQMTRERAEIDARMQTLSASERESVA
LTRDVKVAEDMYMSLRSKVEQLSLMLSDSSTQMRVVDAAIAPVTPVGLGAWPFASAGALLGLCLGVAAINLRQRMRPSVA
SAADAEQRLGMAMLGDIAFSNEQTELERLVEAKRRLGIASGFVLPPNVRLGRPESVTSVIDAATAAAPEDERARAERLLR
QGLHDQFLLARRAPHSLAVEGLRTLRAALHFALRDAPNCVVAVTSPAASAGKTFAAVNLAVLFAEAGQRVLLVDADLRRG
RVADWFDLPAEPGLAEVLAGRSAIAEAVKPSVVNGLFLLSRGAVPANPSELLMLPALAESLRLCAGRFDLVLVDTPPVMA
VADATLVANLAGSTLVVVRADVTATAQVDETLKRLAHANARLAGGILNGVMPRRSNRADFNTINPYLGMPLPRAVAKPPA
LAGQADRVGKN

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the in

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=754, Percent_Identity=27.4535809018568, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1787216, Length=772, Percent_Identity=27.720207253886, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR005700
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 86679; Mature: 86548

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSYAGGPAESATPRREAQPGVTQARALMDHLGWIAAAGVAGAAAGLLVALSAPPQYR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHC
AQALVQVEGRDGGMRSVAQMQGPAAFDAGLLKSRAVVGPVVERLRLDITAQPLRAPLLGA
CEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LVQRFSTPGQPRGTWPASLGYAWGGERLVIASMTVPEALVDQPLTFEVRSDGRYRLMQQD
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCEEEECCCCCEEEEECC
TLLLEGRAGETAMANGIVLRVDKIEAGPGTRFQLTRHDLARTAESVRRGLTVESERSETP
EEEEECCCCCCHHHCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCC
ASLGGAADPLTAPGGTVRVSWQYPDRQLAAQLVNGVTRAYIDGQTDKRRQDAAGTLAFLS
HHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHC
GELPRVQSELTRAEEALTRYRARTGSLQPSRDAQSFLSNSMEYQRQIAALKLERTRLLQR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTPEANEVRTVDSQIQQMTRERAEIDARMQTLSASERESVALTRDVKVAEDMYMSLRSKV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEEEHHHHHHHHHHHHHHHHH
EQLSLMLSDSSTQMRVVDAAIAPVTPVGLGAWPFASAGALLGLCLGVAAINLRQRMRPSV
HHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
ASAADAEQRLGMAMLGDIAFSNEQTELERLVEAKRRLGIASGFVLPPNVRLGRPESVTSV
HHHCCHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCHHCCCEECCCCCCCCCHHHHHH
IDAATAAAPEDERARAERLLRQGLHDQFLLARRAPHSLAVEGLRTLRAALHFALRDAPNC
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCE
VVAVTSPAASAGKTFAAVNLAVLFAEAGQRVLLVDADLRRGRVADWFDLPAEPGLAEVLA
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCCCCHHHHHH
GRSAIAEAVKPSVVNGLFLLSRGAVPANPSELLMLPALAESLRLCAGRFDLVLVDTPPVM
CHHHHHHHHCHHHHHHHHHEECCCCCCCHHHHEEHHHHHHHHHHHCCCCCEEEECCCCCH
AVADATLVANLAGSTLVVVRADVTATAQVDETLKRLAHANARLAGGILNGVMPRRSNRAD
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
FNTINPYLGMPLPRAVAKPPALAGQADRVGKN
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLSYAGGPAESATPRREAQPGVTQARALMDHLGWIAAAGVAGAAAGLLVALSAPPQYR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHC
AQALVQVEGRDGGMRSVAQMQGPAAFDAGLLKSRAVVGPVVERLRLDITAQPLRAPLLGA
CEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LVQRFSTPGQPRGTWPASLGYAWGGERLVIASMTVPEALVDQPLTFEVRSDGRYRLMQQD
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCEEEECCCCCEEEEECC
TLLLEGRAGETAMANGIVLRVDKIEAGPGTRFQLTRHDLARTAESVRRGLTVESERSETP
EEEEECCCCCCHHHCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCC
ASLGGAADPLTAPGGTVRVSWQYPDRQLAAQLVNGVTRAYIDGQTDKRRQDAAGTLAFLS
HHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHC
GELPRVQSELTRAEEALTRYRARTGSLQPSRDAQSFLSNSMEYQRQIAALKLERTRLLQR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTPEANEVRTVDSQIQQMTRERAEIDARMQTLSASERESVALTRDVKVAEDMYMSLRSKV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEEEHHHHHHHHHHHHHHHHH
EQLSLMLSDSSTQMRVVDAAIAPVTPVGLGAWPFASAGALLGLCLGVAAINLRQRMRPSV
HHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
ASAADAEQRLGMAMLGDIAFSNEQTELERLVEAKRRLGIASGFVLPPNVRLGRPESVTSV
HHHCCHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCHHCCCEECCCCCCCCCHHHHHH
IDAATAAAPEDERARAERLLRQGLHDQFLLARRAPHSLAVEGLRTLRAALHFALRDAPNC
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCE
VVAVTSPAASAGKTFAAVNLAVLFAEAGQRVLLVDADLRRGRVADWFDLPAEPGLAEVLA
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCCCCHHHHHH
GRSAIAEAVKPSVVNGLFLLSRGAVPANPSELLMLPALAESLRLCAGRFDLVLVDTPPVM
CHHHHHHHHCHHHHHHHHHEECCCCCCCHHHHEEHHHHHHHHHHHCCCCCEEEECCCCCH
AVADATLVANLAGSTLVVVRADVTATAQVDETLKRLAHANARLAGGILNGVMPRRSNRAD
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
FNTINPYLGMPLPRAVAKPPALAGQADRVGKN
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]