Click here to switch to the map view.

The map label for this gene is mraY [H]

Identifier: 113477977

GI number: 113477977

Start: 7058865

End: 7059953

Strand: Reverse

Name: mraY [H]

Synonym: Tery_4589

Alternate gene names: 113477977

Gene position: 7059953-7058865 (Counterclockwise)

Preceding gene: 113477978

Following gene: 113477976

Centisome position: 91.09

GC content: 37.28

Gene sequence:

>1089_bases
ATGCAAAATAAACTAACTTTTGGTAAGTCTTTCACCATTACGGGAAAAAATTTATTATTGGTTCTGAGTTTAGGGTTAAG
CTGCTTTGCCTTGATTCTAGATGGTATGGCTAATAGGATTTTTAGTATCGGATCTCTTACTTTTCCACTCATTCTTTGTG
GCCTAGTAACTATAAGTTTAGGCTACTGGGTTATACCTATACTAAAAAAGCTAAAAGCTGGACAAATAATCAGGGAAGAT
GGCCCGAAAGCCCACTTACAAAAAGCTGGGACTCCAACAATGGGAGGTATATTTTTTGTACCAGTGGCAGTAGCGATCGC
TCTGGTATTATCTAGATTTCAGCCAGATGTAATAGGGGTATCTTTCCTTACTTTGGCTTATGGGTTTATTGGTTGGCTAG
ATGATTGGCAAATTTTGCAACGCAGGACAAATAAAGGAATATCCCCGAAAATAAAACTGGCTTTGCAGATTGGTTTTGCT
ATTCTATTCTGTGGGTGGCTAGCATGGAGTCAGCCTAGTACGATTACTAATATTGTTTTACCTTTTGGTCTACAATTATC
TTTGGGATTGCTATTTTGGCCTCTGGCAGGTTTTGTTTTAGTTGCTGAAAGTAATGCTACAAATCTTACTGATGGCGTAG
ATGGATTAATGGGGGGTTTAGGGGCAATCACTTTTTTTGGATTAGGAGCTTATTTAGCCCCTACCTCTTTAGAATTAATG
ATTTTCTGTGCTTGTATGAGTGGTAGTTGTCTGGGTTTTGTTGCTCATAATCGTAATCCTGCTAAAGTGTTTATGGGTGA
TACGGGTTCCTTAGCTTTGGGTGGTGGTTTAGCAGCAGTTGCTTTGCTGACTAATACTCTGTGGGTACTTTTTATTGTTA
GTGGAATTTTCTTAATTGAAACTCTTTCTGTTATTGTTCAAGTGAGTTATTATAAAGCAACAAAAAAACATGATGGAGCA
GGCAAACGATTATTTAAAATGGCTCCTTTTCATCATCATTTGGAGCTATCAGGTTGGTTGGAAACTCAAGTGGTAGGAAC
TTTTTACTTAGTTAGTTTAATTTTAGTTAGCTTCTGCTTATTATATTAG

Upstream 100 bases:

>100_bases
AAGATTTTTAATTACTAAAAAGCTATTCACCTATTAGCTAAACTTAACAGTTATGCATTAAATTTTAAGTTTGAAAAAGT
GTGTGTTGAGGAGTGTTTTT

Downstream 100 bases:

>100_bases
TAATTGAAAGACTGAAAATGTTGGTTTCTGTAGTTATACCAATTTATAATGGTGAGAAAGATTTACCAGACTTGATAGAA
TGTCTACGATCGCAAACCTA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MQNKLTFGKSFTITGKNLLLVLSLGLSCFALILDGMANRIFSIGSLTFPLILCGLVTISLGYWVIPILKKLKAGQIIRED
GPKAHLQKAGTPTMGGIFFVPVAVAIALVLSRFQPDVIGVSFLTLAYGFIGWLDDWQILQRRTNKGISPKIKLALQIGFA
ILFCGWLAWSQPSTITNIVLPFGLQLSLGLLFWPLAGFVLVAESNATNLTDGVDGLMGGLGAITFFGLGAYLAPTSLELM
IFCACMSGSCLGFVAHNRNPAKVFMGDTGSLALGGGLAAVALLTNTLWVLFIVSGIFLIETLSVIVQVSYYKATKKHDGA
GKRLFKMAPFHHHLELSGWLETQVVGTFYLVSLILVSFCLLY

Sequences:

>Translated_362_residues
MQNKLTFGKSFTITGKNLLLVLSLGLSCFALILDGMANRIFSIGSLTFPLILCGLVTISLGYWVIPILKKLKAGQIIRED
GPKAHLQKAGTPTMGGIFFVPVAVAIALVLSRFQPDVIGVSFLTLAYGFIGWLDDWQILQRRTNKGISPKIKLALQIGFA
ILFCGWLAWSQPSTITNIVLPFGLQLSLGLLFWPLAGFVLVAESNATNLTDGVDGLMGGLGAITFFGLGAYLAPTSLELM
IFCACMSGSCLGFVAHNRNPAKVFMGDTGSLALGGGLAAVALLTNTLWVLFIVSGIFLIETLSVIVQVSYYKATKKHDGA
GKRLFKMAPFHHHLELSGWLETQVVGTFYLVSLILVSFCLLY
>Mature_362_residues
MQNKLTFGKSFTITGKNLLLVLSLGLSCFALILDGMANRIFSIGSLTFPLILCGLVTISLGYWVIPILKKLKAGQIIRED
GPKAHLQKAGTPTMGGIFFVPVAVAIALVLSRFQPDVIGVSFLTLAYGFIGWLDDWQILQRRTNKGISPKIKLALQIGFA
ILFCGWLAWSQPSTITNIVLPFGLQLSLGLLFWPLAGFVLVAESNATNLTDGVDGLMGGLGAITFFGLGAYLAPTSLELM
IFCACMSGSCLGFVAHNRNPAKVFMGDTGSLALGGGLAAVALLTNTLWVLFIVSGIFLIETLSVIVQVSYYKATKKHDGA
GKRLFKMAPFHHHLELSGWLETQVVGTFYLVSLILVSFCLLY

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=341, Percent_Identity=39.0029325513196, Blast_Score=194, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39016; Mature: 39016

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKLTFGKSFTITGKNLLLVLSLGLSCFALILDGMANRIFSIGSLTFPLILCGLVTISL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYWVIPILKKLKAGQIIREDGPKAHLQKAGTPTMGGIFFVPVAVAIALVLSRFQPDVIGV
HHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
SFLTLAYGFIGWLDDWQILQRRTNKGISPKIKLALQIGFAILFCGWLAWSQPSTITNIVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
PFGLQLSLGLLFWPLAGFVLVAESNATNLTDGVDGLMGGLGAITFFGLGAYLAPTSLELM
CCCHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IFCACMSGSCLGFVAHNRNPAKVFMGDTGSLALGGGLAAVALLTNTLWVLFIVSGIFLIE
HHHHHHCCCEEEEEEECCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVIVQVSYYKATKKHDGAGKRLFKMAPFHHHLELSGWLETQVVGTFYLVSLILVSFCL
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHCEEECCCHHHHHHHHHHHHHHHHHHHHH
LY
HC
>Mature Secondary Structure
MQNKLTFGKSFTITGKNLLLVLSLGLSCFALILDGMANRIFSIGSLTFPLILCGLVTISL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYWVIPILKKLKAGQIIREDGPKAHLQKAGTPTMGGIFFVPVAVAIALVLSRFQPDVIGV
HHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
SFLTLAYGFIGWLDDWQILQRRTNKGISPKIKLALQIGFAILFCGWLAWSQPSTITNIVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
PFGLQLSLGLLFWPLAGFVLVAESNATNLTDGVDGLMGGLGAITFFGLGAYLAPTSLELM
CCCHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IFCACMSGSCLGFVAHNRNPAKVFMGDTGSLALGGGLAAVALLTNTLWVLFIVSGIFLIE
HHHHHHCCCEEEEEEECCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVIVQVSYYKATKKHDGAGKRLFKMAPFHHHLELSGWLETQVVGTFYLVSLILVSFCL
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHCEEECCCHHHHHHHHHHHHHHHHHHHHH
LY
HC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]