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The map label for this gene is galE [H]

Identifier: 113477688

GI number: 113477688

Start: 6600206

End: 6601207

Strand: Reverse

Name: galE [H]

Synonym: Tery_4279

Alternate gene names: 113477688

Gene position: 6601207-6600206 (Counterclockwise)

Preceding gene: 113477689

Following gene: 113477685

Centisome position: 85.18

GC content: 39.92

Gene sequence:

>1002_bases
GTGTCACAAACCAAGCCAACGATTTTAGTGAGTGGGGGAGCAGGATATATTGGTTCCCATGCAGTTCAGGCTTTACAAAA
TGCAGGTTATGATATAGTGATTTTGGATAACCTCGTCTATGGACATCGGGACATTGTAGAAAATGTCCTGAAGGTAGAAA
TGATTGTTGGGGATACTAGCGATCGCTCTTTATTAGATAAAATTTTTGCTACTCACAACATTGCTGCAGTAATGCATTTT
GCAGCATATATTTTTGTCGGTGAATCAGTAAAGGATCCGCAGAAATATTACCACAATAATGTAGTTGGGACACTAACATT
ATTAGAAGCGATGCTTAAAGCATCCATAAAAAAGTTTGTTTTCTCTTCAACTGCTGCTATTTATGGGAAACCACAAACCA
TTCCTATTCCCGAGGATCATCCGAAAAATCCAATTAACCCTTATGGTGCAAGTAAGCGGATGATAGAGCAAATACTTGCA
GATTTTGAGATCGCTTATGATTTTAAGTCGGTTTGTTTTCGCTACTTTAATGCAGCAGGAGCACATCCTAATGGTTTGAC
TGGGGAAGATCATAACCCGGAAACTCATTTAATTCCTCTGGTATTGTTTGCAGCATTGGGCAAGCGAGATTCTATATCAA
TTTTTGGCACAAATTATAAGACTCCTGATGGTACTTGTATTCGAGATTATATTCATGTGTGTGATTTAGCGGATGCTCAT
GTTTTGGGGTTAGAATATTTGTTGAATGGTGGTGAGAGCAATATTTTTAATTTGGGCAATGGTAATGGGTTTTCGGTTAG
GGAAGTGATAGAGACTGTGAAGCAAGTAACTGGTAGAGAGTTTAAAGTGGAGGAGCGCGATCGCCGACCTGGAGATCCAC
CTATTTTGGTAGGGAGTAGTGAGAAAGCCAGGAAAGTGTTGGGTTGGTCTCCGAAATATCCAGAGGTTAAGGAAATAGTT
AGTCATGCTTGGCAGTGGCATCAAAAACGACATGGGAAATGA

Upstream 100 bases:

>100_bases
AGATGATAAAAACTGCCTAAAAAAATCCTTAAGTGAACTGTATTGGGGTATAAGTGCCAAGTACCAAGGCTAAATTAATA
CTTAAAAGGAAACTGAAAAA

Downstream 100 bases:

>100_bases
AAGTCAAAGGTAAGAATGATGGTAGGGGTAAACAAGTAATGATTTTTTTCATCTACCTGATAATAATTCAAGGGATATAT
CAACCAATACAGCGCTTTTT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSQTKPTILVSGGAGYIGSHAVQALQNAGYDIVILDNLVYGHRDIVENVLKVEMIVGDTSDRSLLDKIFATHNIAAVMHF
AAYIFVGESVKDPQKYYHNNVVGTLTLLEAMLKASIKKFVFSSTAAIYGKPQTIPIPEDHPKNPINPYGASKRMIEQILA
DFEIAYDFKSVCFRYFNAAGAHPNGLTGEDHNPETHLIPLVLFAALGKRDSISIFGTNYKTPDGTCIRDYIHVCDLADAH
VLGLEYLLNGGESNIFNLGNGNGFSVREVIETVKQVTGREFKVEERDRRPGDPPILVGSSEKARKVLGWSPKYPEVKEIV
SHAWQWHQKRHGK

Sequences:

>Translated_333_residues
MSQTKPTILVSGGAGYIGSHAVQALQNAGYDIVILDNLVYGHRDIVENVLKVEMIVGDTSDRSLLDKIFATHNIAAVMHF
AAYIFVGESVKDPQKYYHNNVVGTLTLLEAMLKASIKKFVFSSTAAIYGKPQTIPIPEDHPKNPINPYGASKRMIEQILA
DFEIAYDFKSVCFRYFNAAGAHPNGLTGEDHNPETHLIPLVLFAALGKRDSISIFGTNYKTPDGTCIRDYIHVCDLADAH
VLGLEYLLNGGESNIFNLGNGNGFSVREVIETVKQVTGREFKVEERDRRPGDPPILVGSSEKARKVLGWSPKYPEVKEIV
SHAWQWHQKRHGK
>Mature_332_residues
SQTKPTILVSGGAGYIGSHAVQALQNAGYDIVILDNLVYGHRDIVENVLKVEMIVGDTSDRSLLDKIFATHNIAAVMHFA
AYIFVGESVKDPQKYYHNNVVGTLTLLEAMLKASIKKFVFSSTAAIYGKPQTIPIPEDHPKNPINPYGASKRMIEQILAD
FEIAYDFKSVCFRYFNAAGAHPNGLTGEDHNPETHLIPLVLFAALGKRDSISIFGTNYKTPDGTCIRDYIHVCDLADAHV
LGLEYLLNGGESNIFNLGNGNGFSVREVIETVKQVTGREFKVEERDRRPGDPPILVGSSEKARKVLGWSPKYPEVKEIVS
HAWQWHQKRHGK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=336, Percent_Identity=37.5, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI56118217, Length=336, Percent_Identity=37.5, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI189083684, Length=336, Percent_Identity=37.5, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=29.5522388059701, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI42516563, Length=335, Percent_Identity=24.4776119402985, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504031, Length=353, Percent_Identity=25.7790368271955, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=43.2432432432432, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1788353, Length=338, Percent_Identity=29.585798816568, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=28.955223880597, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790049, Length=273, Percent_Identity=30.03663003663, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=38.9380530973451, Blast_Score=231, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=38.3040935672515, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17539532, Length=319, Percent_Identity=24.7648902821317, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI133901786, Length=363, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133901788, Length=363, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17539422, Length=363, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133901790, Length=363, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17539424, Length=363, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17507723, Length=357, Percent_Identity=25.7703081232493, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17568069, Length=333, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115532424, Length=335, Percent_Identity=24.4776119402985, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=40.6432748538012, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=40, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI21356223, Length=320, Percent_Identity=25.9375, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36920; Mature: 36788

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTKPTILVSGGAGYIGSHAVQALQNAGYDIVILDNLVYGHRDIVENVLKVEMIVGDTS
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCHHHCCHHHHHHHHHHHHEECCCC
DRSLLDKIFATHNIAAVMHFAAYIFVGESVKDPQKYYHNNVVGTLTLLEAMLKASIKKFV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FSSTAAIYGKPQTIPIPEDHPKNPINPYGASKRMIEQILADFEIAYDFKSVCFRYFNAAG
HHCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AHPNGLTGEDHNPETHLIPLVLFAALGKRDSISIFGTNYKTPDGTCIRDYIHVCDLADAH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHH
VLGLEYLLNGGESNIFNLGNGNGFSVREVIETVKQVTGREFKVEERDRRPGDPPILVGSS
HHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCCCCCEEECCC
EKARKVLGWSPKYPEVKEIVSHAWQWHQKRHGK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQTKPTILVSGGAGYIGSHAVQALQNAGYDIVILDNLVYGHRDIVENVLKVEMIVGDTS
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCHHHCCHHHHHHHHHHHHEECCCC
DRSLLDKIFATHNIAAVMHFAAYIFVGESVKDPQKYYHNNVVGTLTLLEAMLKASIKKFV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FSSTAAIYGKPQTIPIPEDHPKNPINPYGASKRMIEQILADFEIAYDFKSVCFRYFNAAG
HHCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AHPNGLTGEDHNPETHLIPLVLFAALGKRDSISIFGTNYKTPDGTCIRDYIHVCDLADAH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHH
VLGLEYLLNGGESNIFNLGNGNGFSVREVIETVKQVTGREFKVEERDRRPGDPPILVGSS
HHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCCCCCEEECCC
EKARKVLGWSPKYPEVKEIVSHAWQWHQKRHGK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]