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The map label for this gene is hflX [H]

Identifier: 113477622

GI number: 113477622

Start: 6489249

End: 6490973

Strand: Reverse

Name: hflX [H]

Synonym: Tery_4208

Alternate gene names: 113477622

Gene position: 6490973-6489249 (Counterclockwise)

Preceding gene: 113477624

Following gene: 113477621

Centisome position: 83.75

GC content: 42.2

Gene sequence:

>1725_bases
ATGCCTATCGAAACTATCTACGGAAATCTGAAAGGTCTAAAATCTAGCCAACTTAAACAACTGCAAAGGTTGTATCATCA
GCGACTAACAAGCGATCGCCTAACTACCTCTGAGTTTGCTCAAAGAGTCGCCTCCATCAGTACAGAAGTTGGCCAATCAA
TCTGCGTATATATTAATCGTAGGGGACAAATTATCCGTGTGGGAGTTGGTACACCCCACCAAACCCAAATTCCACCCTTG
GAATTACCTCGTTATGGTAATGGTCGTCTTAGTGGTATTCGTTGTATTGCTACTAACCTGAAAGCAGAAGATCCTTCAGA
AGCTGCTCTAACTGCAATGGTAATTCAACGACTTGATGCTCTAGTGATACTGACGCTAACCGGTGAAGGATTTAAACGTC
GAGGTGGAGGAGCAACAGGTTACATTAAACAAGCTTATCTAGCTCACCTATTACCCATTCCCACACACGAAGGTGTGAAT
ACTGATATTCAAAAGCTGAATTTTTGGAGCGTATCACCTCCTCTTAGTCTTGATGCTTTGGCCAAACAAGACTTCATTGA
CTTAATTGATGGACTAGAAGCAGAATTTCAACGAGAATTTATTGCTCAAGAAGTTGATTCTGACCAAGACCTAGTCCTTT
TGGTGGGGCTAAAAATAGATAAAATGACCAACCAGCAATTTGAAGATGGATTAGCTGAATTAGCTCGACTTGTTGAAACG
GCTGGAGGTAAGGTCCTAAAAACAGTGGATCAGAAGCGATCGCATCCCCATCCCCAAACAGTTGTAGGAGAAGGTAAAGT
TCAAGAAATTGCTCTGAGTGTTCAAACGGTCGGAGCGAACCTAGTTGTATTTGACCAAGACCTTTCCCCTGCTCAAGTAC
GCAACCTAGAAACAAAAATTGGTGTGAGAGTTGTAGACCGCACCGAAGTTATTCTGGACATCTTTGCCCAACGCGCTCAA
TCTCGCGCTGGAAAGTTGCAAGTGGAATTAGCTCAATTAAAATATACTATTCCCCATCTTACAGGCCAAGGCGAAGCAAT
GTCTCGTCTGGGTGGTGGTATTGGTACGAGGGGACCTGGTGAAACTAAGTTAGAAACAGAGCGTCGGGCCATTAACGCTA
GGATATCTCGCTTGCAGAAAGAAGTTAATCAATTACAAGCACACCGTTCCCGCCTAAGACAACATCGCCAACATCAAGAA
GTGCCAACAGTGGCAATAGTGGGATACACGAATGCTGGTAAATCTACATTATTGAATACACTTACCAATTCAGAAGTTTA
TGCAGCAGATAAACTATTTGCTACTCTAGATCCTATTACTCGTCGTTTGAATGTTCCTGATACTGTTACTGGAAAACCAA
CTACAATTGTGATTACTGACACGGTAGGGTTTATTCATGAACTCCCTCCTACTTTGATGAATGCTTTTCGAGCAACTCTA
GAAGAAGTTACAGATGCAGACGCTTTACTTCATGTAGTAGATCTGTCTCACCCGGCTTGGCAAAGTCAAATACGCTCTGT
GATGACTATTTTGCAGGAAATGCCAGAAACTCCAGGACCTGCTTTAGTTGCTTTTAACAAAATTGATGAAGTAGATGGAG
ATACTTTAAAATTTGCTCATGAAGAATATCCGATGGCAGTATTTATTTCTGCTGCAAAAGCTCTAGGTTTGGAAACCTTA
CGTCAACGACTCGCACAGCTTATTGATTATGTTGTTGCTTCTTGA

Upstream 100 bases:

>100_bases
GACAAAGTTAAAATAGGACTAGTATAATTGAAATATTTATATATATCTATAATAATAATCAGAAGTAATATACTGAGGGG
CCACAAATACGTGGCTAGGA

Downstream 100 bases:

>100_bases
AGGAAGAAAGTTTTTTGGGCGTTGATGAATCGAACTATGAAATCTCATGAGAAACCGGGTTACTTGAAGACAGATATTAG
TATGGTATGCTACCTAGTAC

Product: HSR1-related GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MPIETIYGNLKGLKSSQLKQLQRLYHQRLTSDRLTTSEFAQRVASISTEVGQSICVYINRRGQIIRVGVGTPHQTQIPPL
ELPRYGNGRLSGIRCIATNLKAEDPSEAALTAMVIQRLDALVILTLTGEGFKRRGGGATGYIKQAYLAHLLPIPTHEGVN
TDIQKLNFWSVSPPLSLDALAKQDFIDLIDGLEAEFQREFIAQEVDSDQDLVLLVGLKIDKMTNQQFEDGLAELARLVET
AGGKVLKTVDQKRSHPHPQTVVGEGKVQEIALSVQTVGANLVVFDQDLSPAQVRNLETKIGVRVVDRTEVILDIFAQRAQ
SRAGKLQVELAQLKYTIPHLTGQGEAMSRLGGGIGTRGPGETKLETERRAINARISRLQKEVNQLQAHRSRLRQHRQHQE
VPTVAIVGYTNAGKSTLLNTLTNSEVYAADKLFATLDPITRRLNVPDTVTGKPTTIVITDTVGFIHELPPTLMNAFRATL
EEVTDADALLHVVDLSHPAWQSQIRSVMTILQEMPETPGPALVAFNKIDEVDGDTLKFAHEEYPMAVFISAAKALGLETL
RQRLAQLIDYVVAS

Sequences:

>Translated_574_residues
MPIETIYGNLKGLKSSQLKQLQRLYHQRLTSDRLTTSEFAQRVASISTEVGQSICVYINRRGQIIRVGVGTPHQTQIPPL
ELPRYGNGRLSGIRCIATNLKAEDPSEAALTAMVIQRLDALVILTLTGEGFKRRGGGATGYIKQAYLAHLLPIPTHEGVN
TDIQKLNFWSVSPPLSLDALAKQDFIDLIDGLEAEFQREFIAQEVDSDQDLVLLVGLKIDKMTNQQFEDGLAELARLVET
AGGKVLKTVDQKRSHPHPQTVVGEGKVQEIALSVQTVGANLVVFDQDLSPAQVRNLETKIGVRVVDRTEVILDIFAQRAQ
SRAGKLQVELAQLKYTIPHLTGQGEAMSRLGGGIGTRGPGETKLETERRAINARISRLQKEVNQLQAHRSRLRQHRQHQE
VPTVAIVGYTNAGKSTLLNTLTNSEVYAADKLFATLDPITRRLNVPDTVTGKPTTIVITDTVGFIHELPPTLMNAFRATL
EEVTDADALLHVVDLSHPAWQSQIRSVMTILQEMPETPGPALVAFNKIDEVDGDTLKFAHEEYPMAVFISAAKALGLETL
RQRLAQLIDYVVAS
>Mature_573_residues
PIETIYGNLKGLKSSQLKQLQRLYHQRLTSDRLTTSEFAQRVASISTEVGQSICVYINRRGQIIRVGVGTPHQTQIPPLE
LPRYGNGRLSGIRCIATNLKAEDPSEAALTAMVIQRLDALVILTLTGEGFKRRGGGATGYIKQAYLAHLLPIPTHEGVNT
DIQKLNFWSVSPPLSLDALAKQDFIDLIDGLEAEFQREFIAQEVDSDQDLVLLVGLKIDKMTNQQFEDGLAELARLVETA
GGKVLKTVDQKRSHPHPQTVVGEGKVQEIALSVQTVGANLVVFDQDLSPAQVRNLETKIGVRVVDRTEVILDIFAQRAQS
RAGKLQVELAQLKYTIPHLTGQGEAMSRLGGGIGTRGPGETKLETERRAINARISRLQKEVNQLQAHRSRLRQHRQHQEV
PTVAIVGYTNAGKSTLLNTLTNSEVYAADKLFATLDPITRRLNVPDTVTGKPTTIVITDTVGFIHELPPTLMNAFRATLE
EVTDADALLHVVDLSHPAWQSQIRSVMTILQEMPETPGPALVAFNKIDEVDGDTLKFAHEEYPMAVFISAAKALGLETLR
QRLAQLIDYVVAS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=237, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI310133116, Length=226, Percent_Identity=34.070796460177, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=34.9056603773585, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=34.9056603773585, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=34.9056603773585, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=34.9056603773585, Blast_Score=122, Evalue=9e-28,
Organism=Escherichia coli, GI1790615, Length=352, Percent_Identity=46.0227272727273, Blast_Score=282, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17561038, Length=235, Percent_Identity=29.7872340425532, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24650079, Length=358, Percent_Identity=30.7262569832402, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 63210; Mature: 63079

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIETIYGNLKGLKSSQLKQLQRLYHQRLTSDRLTTSEFAQRVASISTEVGQSICVYINR
CCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEC
RGQIIRVGVGTPHQTQIPPLELPRYGNGRLSGIRCIATNLKAEDPSEAALTAMVIQRLDA
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCE
LVILTLTGEGFKRRGGGATGYIKQAYLAHLLPIPTHEGVNTDIQKLNFWSVSPPLSLDAL
EEEEEECCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCEEEECCCCCCHHHH
AKQDFIDLIDGLEAEFQREFIAQEVDSDQDLVLLVGLKIDKMTNQQFEDGLAELARLVET
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AGGKVLKTVDQKRSHPHPQTVVGEGKVQEIALSVQTVGANLVVFDQDLSPAQVRNLETKI
CCCHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHEECCCEEEEEECCCCHHHHHCCHHHH
GVRVVDRTEVILDIFAQRAQSRAGKLQVELAQLKYTIPHLTGQGEAMSRLGGGIGTRGPG
CEEEECHHHHHHHHHHHHHHHCCCCEEEEHHHHHEECCCCCCCCHHHHHHCCCCCCCCCC
ETKLETERRAINARISRLQKEVNQLQAHRSRLRQHRQHQEVPTVAIVGYTNAGKSTLLNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
LTNSEVYAADKLFATLDPITRRLNVPDTVTGKPTTIVITDTVGFIHELPPTLMNAFRATL
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHH
EEVTDADALLHVVDLSHPAWQSQIRSVMTILQEMPETPGPALVAFNKIDEVDGDTLKFAH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEHHH
EEYPMAVFISAAKALGLETLRQRLAQLIDYVVAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIETIYGNLKGLKSSQLKQLQRLYHQRLTSDRLTTSEFAQRVASISTEVGQSICVYINR
CCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEC
RGQIIRVGVGTPHQTQIPPLELPRYGNGRLSGIRCIATNLKAEDPSEAALTAMVIQRLDA
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCE
LVILTLTGEGFKRRGGGATGYIKQAYLAHLLPIPTHEGVNTDIQKLNFWSVSPPLSLDAL
EEEEEECCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCEEEECCCCCCHHHH
AKQDFIDLIDGLEAEFQREFIAQEVDSDQDLVLLVGLKIDKMTNQQFEDGLAELARLVET
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AGGKVLKTVDQKRSHPHPQTVVGEGKVQEIALSVQTVGANLVVFDQDLSPAQVRNLETKI
CCCHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHEECCCEEEEEECCCCHHHHHCCHHHH
GVRVVDRTEVILDIFAQRAQSRAGKLQVELAQLKYTIPHLTGQGEAMSRLGGGIGTRGPG
CEEEECHHHHHHHHHHHHHHHCCCCEEEEHHHHHEECCCCCCCCHHHHHHCCCCCCCCCC
ETKLETERRAINARISRLQKEVNQLQAHRSRLRQHRQHQEVPTVAIVGYTNAGKSTLLNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
LTNSEVYAADKLFATLDPITRRLNVPDTVTGKPTTIVITDTVGFIHELPPTLMNAFRATL
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHH
EEVTDADALLHVVDLSHPAWQSQIRSVMTILQEMPETPGPALVAFNKIDEVDGDTLKFAH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEHHH
EEYPMAVFISAAKALGLETLRQRLAQLIDYVVAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]