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The map label for this gene is fur [H]

Identifier: 113476917

GI number: 113476917

Start: 5213167

End: 5213691

Strand: Reverse

Name: fur [H]

Synonym: Tery_3404

Alternate gene names: 113476917

Gene position: 5213691-5213167 (Counterclockwise)

Preceding gene: 113476922

Following gene: 113476913

Centisome position: 67.27

GC content: 34.1

Gene sequence:

>525_bases
ATGGCATTTTATAATCATGATTCACTTAAGTCTGAACTAAATCAAAGAGGTTGGCGTTTAACTGCTCAAAGGGAAACTAT
CCTGCAAGTGCTTCAACGTCTACCTCAAGGCAAACACTTAAGTGCAGAAGAAATATATAATCTGTTGTTAAATCAAAAGG
AACAAATTAGTCTGTCTACTGTTTATCGAACACTACATTTATTGACAAAAGTAGGTATTCTCAGGGAACTAGAACTAGCC
GAAGGACATAAACATTATGAGATGAGTGCCCCCAACCTTAATAAACATCACCATTTAGTTTGTCTTCAATGTCATAAAAC
CTTTGAATTTAATGATGATTCCATAATGAAAATTAGTCAGAAGCAGGCTGAAAAAGAAGGTGTTGAAATGTTAGACTGTC
AACTAACAATTCATGCTATTTGTATTGAGGCTTTACGCAAAGGTTGGCCTGCTTTAGTAGCTACTAATTGGTCTTGTCCA
AGAACTAACTTAGAAATAACATCTAAATCAAATAATCACAAATAA

Upstream 100 bases:

>100_bases
AAGTTATCAAACTCAGCCATAGATATTTTTGACTTTTGTATTTTAGACTCTTGTCTTCCTATATAAGTTGCTTAAGAAAT
AAATCTGGATAATTTTAAAA

Downstream 100 bases:

>100_bases
TCAAAAGGCAACTCTGGAGGAGGAGGGGGAGCTACCAAATATTCAAGAACTGCTTTATGACTCTCGCGGTTAGTTTGAAC
TTCTGCAGCGATCGCCTCAA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MAFYNHDSLKSELNQRGWRLTAQRETILQVLQRLPQGKHLSAEEIYNLLLNQKEQISLSTVYRTLHLLTKVGILRELELA
EGHKHYEMSAPNLNKHHHLVCLQCHKTFEFNDDSIMKISQKQAEKEGVEMLDCQLTIHAICIEALRKGWPALVATNWSCP
RTNLEITSKSNNHK

Sequences:

>Translated_174_residues
MAFYNHDSLKSELNQRGWRLTAQRETILQVLQRLPQGKHLSAEEIYNLLLNQKEQISLSTVYRTLHLLTKVGILRELELA
EGHKHYEMSAPNLNKHHHLVCLQCHKTFEFNDDSIMKISQKQAEKEGVEMLDCQLTIHAICIEALRKGWPALVATNWSCP
RTNLEITSKSNNHK
>Mature_173_residues
AFYNHDSLKSELNQRGWRLTAQRETILQVLQRLPQGKHLSAEEIYNLLLNQKEQISLSTVYRTLHLLTKVGILRELELAE
GHKHYEMSAPNLNKHHHLVCLQCHKTFEFNDDSIMKISQKQAEKEGVEMLDCQLTIHAICIEALRKGWPALVATNWSCPR
TNLEITSKSNNHK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=134, Percent_Identity=35.0746268656716, Blast_Score=84, Evalue=3e-18,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 20163; Mature: 20032

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFYNHDSLKSELNQRGWRLTAQRETILQVLQRLPQGKHLSAEEIYNLLLNQKEQISLST
CCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHH
VYRTLHLLTKVGILRELELAEGHKHYEMSAPNLNKHHHLVCLQCHKTFEFNDDSIMKISQ
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
KQAEKEGVEMLDCQLTIHAICIEALRKGWPALVATNWSCPRTNLEITSKSNNHK
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AFYNHDSLKSELNQRGWRLTAQRETILQVLQRLPQGKHLSAEEIYNLLLNQKEQISLST
CCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHH
VYRTLHLLTKVGILRELELAEGHKHYEMSAPNLNKHHHLVCLQCHKTFEFNDDSIMKISQ
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
KQAEKEGVEMLDCQLTIHAICIEALRKGWPALVATNWSCPRTNLEITSKSNNHK
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]