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The map label for this gene is ndhD2

Identifier: 113476768

GI number: 113476768

Start: 4964016

End: 4965701

Strand: Reverse

Name: ndhD2

Synonym: Tery_3241

Alternate gene names: 113476768

Gene position: 4965701-4964016 (Counterclockwise)

Preceding gene: 113476769

Following gene: 113476767

Centisome position: 64.07

GC content: 39.8

Gene sequence:

>1686_bases
ATGATGGAGACTCAATTTCCCTGGCTGACCACTATAGTCCTACTGCCACTTCTGGCAGCTCTACTCATTCCATTCATACC
TGATCAAAACGGAAAAACTATGAGATGGTATGGTCTTGGTGTAGGTGCTATAGACTTTGCCTTAATGTGCTACGTTTTCT
GGAAGTACTACAATGCTAGTGACTCTGGCTTTCAACTGGTAGAAAAATATCTTTGGCTTCCTCAAATAGGTTTAAGTTGG
GCAGTATCAGTAGATGGTCTATCTATGCCACTAGTACTTTTAGCTGGTTTAGTGACAACACTCTCAATATTCGCAGCGTG
GCAAGTAGACTACAAACCACGTCTTTTCTATTTCTTGATGCTGGTTCTGTACTCTGCCCAGATAGGAGTATTTGTTGCTC
AAGACCTAATGCTACTCTTCATTATGTGGGAACTAGAATTAGTTCCTGTATACCTACTCATCTCAATATGGGGAGGTAAA
AAACGTCGCTACGCAGCAACAAAATTCTTGCTCTACACAGCAGCGGCTTCTATATTTATTCTAGTGGCAGCCTTGGGAAT
GGCCCTCTACGGTGAAGGCAATACTACCTTTGATATGGTGGAATTAGGCCTAAAAGATTATCCACTAGCTTTTGAACTTC
TGCTATATTTAGGATTACTTATAACTTTTGGTGTCAAGTTAGCGGTTTTCCCTCTACATACATGGCTACCTGATGCTCAT
GGAGAAGCTTCTGCACCTGTATCAATGATACTTGCTGGTGTATTATTAAAAATGGGCGGATATGGATTAATTCGTCTGAA
CTTAGAAATGCTTTCTGATGCCCATGTTTATTTTGCTCCTGTTCTAGCAATTTTGGGCGTGGTTAATATTGTTTATGGTG
GCTTAAATTCTTTTGGTCAATCTAACATGAAACGCCGTTTGGCCTACTCTTCCGTTGCTCACATGGGTTTTGTGTTGTTG
GGTATTGCCTCATTCACTGACTTGGGAATAAGTGGAGCTTTGCTACAGATGATTTCTCATGGTTTAATTGCTGCAGTCTT
GTTCTTCCTGGCAGGTGTAACTTATGACCGCCTCCACACTTTGGCATTAGATGAAATGGGTGGTCTTGGTCAAGTGATGC
CAAAAATATTTGCTCTATTTACAATAAGTGCAATGGCATCTTTAGCTCTCCCTGGAATGAGTGGTTTTGCGAGTGAGTTA
ATGGTATTTGTGGGAGTAACTAGCAGCGATATTTACAGCTCTACTTTTTGTACTGTGACAGTATTCTTAGCAGCAGTTGG
TCTGATATTGACTCCTATATATTTGCTTTCTATGTTGCGTCAAATGTTCTACAGCACTGGTAAAGCGCCAGTTTGTTTGC
TCAAGAATACTCCTTATGAAAATGAAGTGTTGGATGAAGCAATTTGTTTTGGTACTAACTGTGTTTTACCTGCAAAAGCT
GTTTATACTGATGCCAAACCAAGGGAAGTAGCGATCGCTGCTTGTTTCTTAGTTTTAATTATCGGAATTGGTTTATATCC
TAAAATAGCAACTAGAATGTATGATGCAAAGATAGTTGCAGTAAACACTCAAGTACGTCAATCATACACTTTTGCTAAAG
CTGATCCTCAACTGTTTGCTAAAGGATTTTTATTTCCCAGAATTCCTGAGTCTGAAGTATTATCTGTTTCTGGTCTATTA
AGATAG

Upstream 100 bases:

>100_bases
TATATATATTTATGCAAATATCTATTTACAAAGATTTACAAAATTTAGTAATATGCAGTAGTATAAAAAAAAATATAAGT
AAGTATTTGTGCTCACTGTT

Downstream 100 bases:

>100_bases
GAATTAACTTTGAGCTTTAATATAGTGATATGCAGTAGGGGTATTTAATATTATACCTCTACTATTTTTTATGCAAAATT
TCTGAGTATTACAGCGCATG

Product: NAD(P)H-quinone oxidoreductase subunit 4

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I, chain 4 2; NDH-1, chain 4 2

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MMETQFPWLTTIVLLPLLAALLIPFIPDQNGKTMRWYGLGVGAIDFALMCYVFWKYYNASDSGFQLVEKYLWLPQIGLSW
AVSVDGLSMPLVLLAGLVTTLSIFAAWQVDYKPRLFYFLMLVLYSAQIGVFVAQDLMLLFIMWELELVPVYLLISIWGGK
KRRYAATKFLLYTAAASIFILVAALGMALYGEGNTTFDMVELGLKDYPLAFELLLYLGLLITFGVKLAVFPLHTWLPDAH
GEASAPVSMILAGVLLKMGGYGLIRLNLEMLSDAHVYFAPVLAILGVVNIVYGGLNSFGQSNMKRRLAYSSVAHMGFVLL
GIASFTDLGISGALLQMISHGLIAAVLFFLAGVTYDRLHTLALDEMGGLGQVMPKIFALFTISAMASLALPGMSGFASEL
MVFVGVTSSDIYSSTFCTVTVFLAAVGLILTPIYLLSMLRQMFYSTGKAPVCLLKNTPYENEVLDEAICFGTNCVLPAKA
VYTDAKPREVAIAACFLVLIIGIGLYPKIATRMYDAKIVAVNTQVRQSYTFAKADPQLFAKGFLFPRIPESEVLSVSGLL
R

Sequences:

>Translated_561_residues
MMETQFPWLTTIVLLPLLAALLIPFIPDQNGKTMRWYGLGVGAIDFALMCYVFWKYYNASDSGFQLVEKYLWLPQIGLSW
AVSVDGLSMPLVLLAGLVTTLSIFAAWQVDYKPRLFYFLMLVLYSAQIGVFVAQDLMLLFIMWELELVPVYLLISIWGGK
KRRYAATKFLLYTAAASIFILVAALGMALYGEGNTTFDMVELGLKDYPLAFELLLYLGLLITFGVKLAVFPLHTWLPDAH
GEASAPVSMILAGVLLKMGGYGLIRLNLEMLSDAHVYFAPVLAILGVVNIVYGGLNSFGQSNMKRRLAYSSVAHMGFVLL
GIASFTDLGISGALLQMISHGLIAAVLFFLAGVTYDRLHTLALDEMGGLGQVMPKIFALFTISAMASLALPGMSGFASEL
MVFVGVTSSDIYSSTFCTVTVFLAAVGLILTPIYLLSMLRQMFYSTGKAPVCLLKNTPYENEVLDEAICFGTNCVLPAKA
VYTDAKPREVAIAACFLVLIIGIGLYPKIATRMYDAKIVAVNTQVRQSYTFAKADPQLFAKGFLFPRIPESEVLSVSGLL
R
>Mature_561_residues
MMETQFPWLTTIVLLPLLAALLIPFIPDQNGKTMRWYGLGVGAIDFALMCYVFWKYYNASDSGFQLVEKYLWLPQIGLSW
AVSVDGLSMPLVLLAGLVTTLSIFAAWQVDYKPRLFYFLMLVLYSAQIGVFVAQDLMLLFIMWELELVPVYLLISIWGGK
KRRYAATKFLLYTAAASIFILVAALGMALYGEGNTTFDMVELGLKDYPLAFELLLYLGLLITFGVKLAVFPLHTWLPDAH
GEASAPVSMILAGVLLKMGGYGLIRLNLEMLSDAHVYFAPVLAILGVVNIVYGGLNSFGQSNMKRRLAYSSVAHMGFVLL
GIASFTDLGISGALLQMISHGLIAAVLFFLAGVTYDRLHTLALDEMGGLGQVMPKIFALFTISAMASLALPGMSGFASEL
MVFVGVTSSDIYSSTFCTVTVFLAAVGLILTPIYLLSMLRQMFYSTGKAPVCLLKNTPYENEVLDEAICFGTNCVLPAKA
VYTDAKPREVAIAACFLVLIIGIGLYPKIATRMYDAKIVAVNTQVRQSYTFAKADPQLFAKGFLFPRIPESEVLSVSGLL
R

Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran

COG id: COG1008

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 4 (chain M)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family

Homologues:

Organism=Homo sapiens, GI251831116, Length=333, Percent_Identity=31.5315315315315, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI251831117, Length=333, Percent_Identity=27.9279279279279, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1788613, Length=460, Percent_Identity=36.9565217391304, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1788827, Length=295, Percent_Identity=25.7627118644068, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788831, Length=298, Percent_Identity=30.5369127516779, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788614, Length=476, Percent_Identity=25, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693160, Length=250, Percent_Identity=36.4, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI2367154, Length=222, Percent_Identity=30.1801801801802, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788829, Length=411, Percent_Identity=26.5206812652068, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU4C2_TRIEI (Q10ZG8)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722829.1
- STRING:   Q10ZG8
- GeneID:   4243662
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_3241
- NMPDR:   fig|203124.1.peg.2680
- eggNOG:   COG1008
- HOGENOM:   HBG643593
- OMA:   VTSSDIY
- PhylomeDB:   Q10ZG8
- ProtClustDB:   PRK12561
- BioCyc:   TERY203124:TERY_3241-MONOMER
- HAMAP:   MF_00491
- InterPro:   IPR022997
- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918
- PRINTS:   PR01437
- TIGRFAMs:   TIGR01972

Pfam domain/function: PF00361 Oxidored_q1

EC number: 1.6.5.3

Molecular weight: Translated: 61479; Mature: 61479

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x171a1220)-; HASH(0x18a7f070)-; HASH(0x173eebd0)-; HASH(0x40678e00)-; HASH(0x191e74d4)-; HASH(0x19e5bd68)-; HASH(0x19fc89c4)-; HASH(0x192eaf50)-; HASH(0x405fc0c0)-; HASH(0x406548e4)-; HASH(0x17b7c84c)-; HASH(0x40652ac0)-; HASH(0x194d68f0)-; HASH(0x19d4ac90)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMETQFPWLTTIVLLPLLAALLIPFIPDQNGKTMRWYGLGVGAIDFALMCYVFWKYYNAS
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCC
DSGFQLVEKYLWLPQIGLSWAVSVDGLSMPLVLLAGLVTTLSIFAAWQVDYKPRLFYFLM
CHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LVLYSAQIGVFVAQDLMLLFIMWELELVPVYLLISIWGGKKRRYAATKFLLYTAAASIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LVAALGMALYGEGNTTFDMVELGLKDYPLAFELLLYLGLLITFGVKLAVFPLHTWLPDAH
HHHHHHHHEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
GEASAPVSMILAGVLLKMGGYGLIRLNLEMLSDAHVYFAPVLAILGVVNIVYGGLNSFGQ
CCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
SNMKRRLAYSSVAHMGFVLLGIASFTDLGISGALLQMISHGLIAAVLFFLAGVTYDRLHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LALDEMGGLGQVMPKIFALFTISAMASLALPGMSGFASELMVFVGVTSSDIYSSTFCTVT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCHHHHHHHHHHH
VFLAAVGLILTPIYLLSMLRQMFYSTGKAPVCLLKNTPYENEVLDEAICFGTNCVLPAKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHH
VYTDAKPREVAIAACFLVLIIGIGLYPKIATRMYDAKIVAVNTQVRQSYTFAKADPQLFA
HHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEHHHHHHCCCCCCCHHHHH
KGFLFPRIPESEVLSVSGLLR
HCCCCCCCCHHHHHHHHCCCH
>Mature Secondary Structure
MMETQFPWLTTIVLLPLLAALLIPFIPDQNGKTMRWYGLGVGAIDFALMCYVFWKYYNAS
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCC
DSGFQLVEKYLWLPQIGLSWAVSVDGLSMPLVLLAGLVTTLSIFAAWQVDYKPRLFYFLM
CHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LVLYSAQIGVFVAQDLMLLFIMWELELVPVYLLISIWGGKKRRYAATKFLLYTAAASIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LVAALGMALYGEGNTTFDMVELGLKDYPLAFELLLYLGLLITFGVKLAVFPLHTWLPDAH
HHHHHHHHEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
GEASAPVSMILAGVLLKMGGYGLIRLNLEMLSDAHVYFAPVLAILGVVNIVYGGLNSFGQ
CCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
SNMKRRLAYSSVAHMGFVLLGIASFTDLGISGALLQMISHGLIAAVLFFLAGVTYDRLHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LALDEMGGLGQVMPKIFALFTISAMASLALPGMSGFASELMVFVGVTSSDIYSSTFCTVT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCHHHHHHHHHHH
VFLAAVGLILTPIYLLSMLRQMFYSTGKAPVCLLKNTPYENEVLDEAICFGTNCVLPAKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHH
VYTDAKPREVAIAACFLVLIIGIGLYPKIATRMYDAKIVAVNTQVRQSYTFAKADPQLFA
HHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEHHHHHHCCCCCCCHHHHH
KGFLFPRIPESEVLSVSGLLR
HCCCCCCCCHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA