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The map label for this gene is carA [H]

Identifier: 113475946

GI number: 113475946

Start: 3579255

End: 3580409

Strand: Direct

Name: carA [H]

Synonym: Tery_2310

Alternate gene names: 113475946

Gene position: 3579255-3580409 (Clockwise)

Preceding gene: 113475944

Following gene: 113475947

Centisome position: 46.18

GC content: 41.04

Gene sequence:

>1155_bases
ATGTCAATCTCAGCTCAACCTGCTTTACTCGTCTTAGCAGATGGAACCTCTTACTGTGGCTTATCTTTCGGTGCTCCCGG
AACCACCATAGGAGAAGTAGTATTTAACACAGGAATGACTGGTTATCAAGAAGTTCTCACAGACCCAAGTTATTGCGGGC
AAATAGTTACTTTTACCTACCCAGAGTTGGGAAACACAGGAGTTAACTCTGAAGATGAAGAGTCCAACAAACCACAGATT
CAAGGTGCGATCGCTCGAAATATTTGTCCACGTCCTAGTAACTGGCGTTCTACTAAGTCCTTACCAGAATATCTACAAGA
GCATAAAATTCAAGGAATTTACGGTGTAGATACCCGCGCTTTGACTCGGAAAATTCGGACTGTAGGAGCAATGAATGGAG
CAATTTCTACAGAAATTCTCAATCCAACTGAATTGCTAGAACAAGTTCAGTTTGCTCCTAGCATGGCAGGATTAAATTTA
GTTCAGAAAGTAACAACTAAAGAAACTTATCAATGGTCTGAACCAACAAACCCAGACTGGGAGTTTAACCTTTCTGTCTC
TGGTAATACAGGAGAAAAATTTACAGTTGTGGCCATTGACTTTGGAGTGAAAAAAAATATCCTTCGACGTTTAGCTAGTT
ATGGTTGTCAAGTCATAGTTGTTCCTGCCGATACACCACCAGAAGAAATTCTCAAGCATAATCCTGATGGAATTTTCCTT
TCTAATGGACCGGGAGACCCTTCTGCAGTGAGGGAAGGTATTGAAACTACTAAAGAGTTGCTAAAATCATCTAAACCTGT
ATTTGGTATTTGCATGGGACATCAGGTTCTCGGTCTAGCCTTGGGAGCAGACACTTTTAAGCTAAAATTTGGTCATCGGG
GTCTTAATCAACCAGCAGGTTTGCAACAACGAGTAGAAATTACTAGTCAAAATCATGGATTTGCCATTAATGCAGATTCT
TTAGTGGCTGAATTAGAAATTACCCATCTCAACTTGAACGACCAAACTGTAGCCGGTCTAAGGCATAAATCTTTACCCTT
ATTCTCAGTACAGTACCACCCGGAAGCAAGTCCCGGCCCTCATGACGCTGATTATTTGTTTGAACGTTTCGTTCAAGCAA
TGAAAGATACTCGCAAAGTTAAAGCTTTGAGTTGA

Upstream 100 bases:

>100_bases
TATTATCTATACTAATCATTAAAATCTCAAACTCAGTTCCTGAATTAGATATTCTGAAGTGATCTGATTTTTTTTATACT
AATTAAATAGAGGAATTAAA

Downstream 100 bases:

>100_bases
GCTTAGTTAACTATTACTGATTTGATAATATTTATTAATAGAAATTTATATATACTGGTACGGCTATACTTATTAAAATC
TATAAGTAGGTAAGCCTTAA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSISAQPALLVLADGTSYCGLSFGAPGTTIGEVVFNTGMTGYQEVLTDPSYCGQIVTFTYPELGNTGVNSEDEESNKPQI
QGAIARNICPRPSNWRSTKSLPEYLQEHKIQGIYGVDTRALTRKIRTVGAMNGAISTEILNPTELLEQVQFAPSMAGLNL
VQKVTTKETYQWSEPTNPDWEFNLSVSGNTGEKFTVVAIDFGVKKNILRRLASYGCQVIVVPADTPPEEILKHNPDGIFL
SNGPGDPSAVREGIETTKELLKSSKPVFGICMGHQVLGLALGADTFKLKFGHRGLNQPAGLQQRVEITSQNHGFAINADS
LVAELEITHLNLNDQTVAGLRHKSLPLFSVQYHPEASPGPHDADYLFERFVQAMKDTRKVKALS

Sequences:

>Translated_384_residues
MSISAQPALLVLADGTSYCGLSFGAPGTTIGEVVFNTGMTGYQEVLTDPSYCGQIVTFTYPELGNTGVNSEDEESNKPQI
QGAIARNICPRPSNWRSTKSLPEYLQEHKIQGIYGVDTRALTRKIRTVGAMNGAISTEILNPTELLEQVQFAPSMAGLNL
VQKVTTKETYQWSEPTNPDWEFNLSVSGNTGEKFTVVAIDFGVKKNILRRLASYGCQVIVVPADTPPEEILKHNPDGIFL
SNGPGDPSAVREGIETTKELLKSSKPVFGICMGHQVLGLALGADTFKLKFGHRGLNQPAGLQQRVEITSQNHGFAINADS
LVAELEITHLNLNDQTVAGLRHKSLPLFSVQYHPEASPGPHDADYLFERFVQAMKDTRKVKALS
>Mature_383_residues
SISAQPALLVLADGTSYCGLSFGAPGTTIGEVVFNTGMTGYQEVLTDPSYCGQIVTFTYPELGNTGVNSEDEESNKPQIQ
GAIARNICPRPSNWRSTKSLPEYLQEHKIQGIYGVDTRALTRKIRTVGAMNGAISTEILNPTELLEQVQFAPSMAGLNLV
QKVTTKETYQWSEPTNPDWEFNLSVSGNTGEKFTVVAIDFGVKKNILRRLASYGCQVIVVPADTPPEEILKHNPDGIFLS
NGPGDPSAVREGIETTKELLKSSKPVFGICMGHQVLGLALGADTFKLKFGHRGLNQPAGLQQRVEITSQNHGFAINADSL
VAELEITHLNLNDQTVAGLRHKSLPLFSVQYHPEASPGPHDADYLFERFVQAMKDTRKVKALS

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=382, Percent_Identity=40.8376963350785, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI21361331, Length=389, Percent_Identity=38.560411311054, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI169790915, Length=389, Percent_Identity=38.560411311054, Blast_Score=253, Evalue=3e-67,
Organism=Escherichia coli, GI1786215, Length=380, Percent_Identity=48.1578947368421, Blast_Score=358, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI193204318, Length=386, Percent_Identity=38.60103626943, Blast_Score=253, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6322331, Length=399, Percent_Identity=39.5989974937343, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6324878, Length=388, Percent_Identity=38.4020618556701, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI45555749, Length=395, Percent_Identity=36.4556962025316, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24642586, Length=395, Percent_Identity=36.4556962025316, Blast_Score=236, Evalue=3e-62,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41816; Mature: 41685

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISAQPALLVLADGTSYCGLSFGAPGTTIGEVVFNTGMTGYQEVLTDPSYCGQIVTFTY
CCCCCCCEEEEEECCCCCCCEECCCCCCHHHHHHHHCCCCHHHHHHCCHHHCCCEEEEEC
PELGNTGVNSEDEESNKPQIQGAIARNICPRPSNWRSTKSLPEYLQEHKIQGIYGVDTRA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCHHH
LTRKIRTVGAMNGAISTEILNPTELLEQVQFAPSMAGLNLVQKVTTKETYQWSEPTNPDW
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEECCCCCCCCE
EFNLSVSGNTGEKFTVVAIDFGVKKNILRRLASYGCQVIVVPADTPPEEILKHNPDGIFL
EEEEEEECCCCCEEEEEEEECCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCEEEE
SNGPGDPSAVREGIETTKELLKSSKPVFGICMGHQVLGLALGADTFKLKFGHRGLNQPAG
ECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHEEHHEECCCEEEEEECCCCCCCCCC
LQQRVEITSQNHGFAINADSLVAELEITHLNLNDQTVAGLRHKSLPLFSVQYHPEASPGP
CHHHHHEECCCCCEEEEHHHEEEEEEEEEECCCCHHHHCCHHCCCCEEEEEECCCCCCCC
HDADYLFERFVQAMKDTRKVKALS
CCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SISAQPALLVLADGTSYCGLSFGAPGTTIGEVVFNTGMTGYQEVLTDPSYCGQIVTFTY
CCCCCCEEEEEECCCCCCCEECCCCCCHHHHHHHHCCCCHHHHHHCCHHHCCCEEEEEC
PELGNTGVNSEDEESNKPQIQGAIARNICPRPSNWRSTKSLPEYLQEHKIQGIYGVDTRA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCHHH
LTRKIRTVGAMNGAISTEILNPTELLEQVQFAPSMAGLNLVQKVTTKETYQWSEPTNPDW
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEECCCCCCCCE
EFNLSVSGNTGEKFTVVAIDFGVKKNILRRLASYGCQVIVVPADTPPEEILKHNPDGIFL
EEEEEEECCCCCEEEEEEEECCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCEEEE
SNGPGDPSAVREGIETTKELLKSSKPVFGICMGHQVLGLALGADTFKLKFGHRGLNQPAG
ECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHEEHHEECCCEEEEEECCCCCCCCCC
LQQRVEITSQNHGFAINADSLVAELEITHLNLNDQTVAGLRHKSLPLFSVQYHPEASPGP
CHHHHHEECCCCCEEEEHHHEEEEEEEEEECCCCHHHHCCHHCCCCEEEEEECCCCCCCC
HDADYLFERFVQAMKDTRKVKALS
CCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]