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The map label for this gene is trpD

Identifier: 113475944

GI number: 113475944

Start: 3577180

End: 3578250

Strand: Direct

Name: trpD

Synonym: Tery_2308

Alternate gene names: 113475944

Gene position: 3577180-3578250 (Clockwise)

Preceding gene: 113475943

Following gene: 113475946

Centisome position: 46.16

GC content: 40.9

Gene sequence:

>1071_bases
ATGAACAACTCCTCCATAAACGAATGGCCTAGTTTATTACAGCAATTACTTGATGGCCAATCTTTATCATCCTCCCAAGC
CTCAAACTTAATGCAAGGATGGCTACAAGAAGAAATTCCACCTGTTCTATCAGGAGCAATATTAGCAGCCTTACAAGCCA
AAGGTGTATCTGCTCAAGAATTAGCTGGTATGGCAAAAGTATTACAATCTTTATCCTTAACAAAAGAATACCATAATAAC
AATATTCCCATCACCAACTTTCAATACCCTATCATTGATACCTGCGGTACTGGTGGAGATGGAGCCTCAACATTCAATAT
TTCCACTGCAGTTGCTTTTGTCCTAGCCGCCGCAGGAGTACCAGTAGCCAAACATGGTAACCGTTCTGCTTCAGGTAAAG
TCGGTTCTGCTGACGTATTAGAAGCATTAGGAATACGTTTGAATGCACCCACAGAAAAAGTAATATCTGCATTATCTGAA
GTAGGAATTACCTTTCTATTTGCACCCGGCTGGCATCCAGCAATGAAATGTGTAGTTCCTCTACGGAGGACTTTAAAAGT
ACGAACCGTGTTTAACCTTTTAGGTCCTTTAGTTAACCCCTTGCGTCCCCAAGCTCAAATTATTGGTGTATACAATTCTA
CACTAGTAAAAACAGTAGCCCAAGCTTTAGGAATATTAGGAGTAGAATATGCGATCGCTCTCCACGGTAGAGAAAAACTT
GACGAAGCTGGTCTAGGCGACATCACTGATATAGCCATATTATCTCATGGTGAGGTAAAAGCCACCTCAATTAACCCCCA
ATATTTAGGCTTAAATTATGCCCCAATAAGTACCTTACAAGGTGGAGACGTAGAGCAAAACGCCGAAATTCTCAAAAACG
TTCTTCAGGGTAAAGGAACTTCTCAACAAACAGATGTAGTGGCTTTGAATAGTTCTCTGGCACTACAGGTAGCGGGCGTT
GTACCACTAGAAGCTCATCAAGAAGGTATTGGCAAAGCTAAAGATATTCTCCAAAGTGGTGCAGCTTGGTTGAAATTAGA
GCAGTTAGTTCAATTCTTATCAATCTTTTGA

Upstream 100 bases:

>100_bases
AACTAAAAAGTCACCCGCTTATGGGCGAGGCTTTAAACCCAATTTTTCCGTAATATTCAACTGTATATTTAAGTACTTCT
ATAACCAGCAAGTTACAATA

Downstream 100 bases:

>100_bases
AATTATTTGAGTCTGCTAAAAATAGGGGAAAAGTTTTAGGAGTTAGGGGTTATATAATGTCTAGTTAACTACTAGAACGT
CTCCGTAATTCTACTATATC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNNSSINEWPSLLQQLLDGQSLSSSQASNLMQGWLQEEIPPVLSGAILAALQAKGVSAQELAGMAKVLQSLSLTKEYHNN
NIPITNFQYPIIDTCGTGGDGASTFNISTAVAFVLAAAGVPVAKHGNRSASGKVGSADVLEALGIRLNAPTEKVISALSE
VGITFLFAPGWHPAMKCVVPLRRTLKVRTVFNLLGPLVNPLRPQAQIIGVYNSTLVKTVAQALGILGVEYAIALHGREKL
DEAGLGDITDIAILSHGEVKATSINPQYLGLNYAPISTLQGGDVEQNAEILKNVLQGKGTSQQTDVVALNSSLALQVAGV
VPLEAHQEGIGKAKDILQSGAAWLKLEQLVQFLSIF

Sequences:

>Translated_356_residues
MNNSSINEWPSLLQQLLDGQSLSSSQASNLMQGWLQEEIPPVLSGAILAALQAKGVSAQELAGMAKVLQSLSLTKEYHNN
NIPITNFQYPIIDTCGTGGDGASTFNISTAVAFVLAAAGVPVAKHGNRSASGKVGSADVLEALGIRLNAPTEKVISALSE
VGITFLFAPGWHPAMKCVVPLRRTLKVRTVFNLLGPLVNPLRPQAQIIGVYNSTLVKTVAQALGILGVEYAIALHGREKL
DEAGLGDITDIAILSHGEVKATSINPQYLGLNYAPISTLQGGDVEQNAEILKNVLQGKGTSQQTDVVALNSSLALQVAGV
VPLEAHQEGIGKAKDILQSGAAWLKLEQLVQFLSIF
>Mature_356_residues
MNNSSINEWPSLLQQLLDGQSLSSSQASNLMQGWLQEEIPPVLSGAILAALQAKGVSAQELAGMAKVLQSLSLTKEYHNN
NIPITNFQYPIIDTCGTGGDGASTFNISTAVAFVLAAAGVPVAKHGNRSASGKVGSADVLEALGIRLNAPTEKVISALSE
VGITFLFAPGWHPAMKCVVPLRRTLKVRTVFNLLGPLVNPLRPQAQIIGVYNSTLVKTVAQALGILGVEYAIALHGREKL
DEAGLGDITDIAILSHGEVKATSINPQYLGLNYAPISTLQGGDVEQNAEILKNVLQGKGTSQQTDVVALNSSLALQVAGV
VPLEAHQEGIGKAKDILQSGAAWLKLEQLVQFLSIF

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=343, Percent_Identity=37.3177842565598, Blast_Score=200, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6320561, Length=296, Percent_Identity=31.0810810810811, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_TRIEI (Q112P2)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722005.1
- ProteinModelPortal:   Q112P2
- SMR:   Q112P2
- STRING:   Q112P2
- GeneID:   4243303
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2308
- NMPDR:   fig|203124.1.peg.4809
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q112P2
- ProtClustDB:   PRK00188
- BioCyc:   TERY203124:TERY_2308-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37482; Mature: 37482

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSSINEWPSLLQQLLDGQSLSSSQASNLMQGWLQEEIPPVLSGAILAALQAKGVSAQE
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHH
LAGMAKVLQSLSLTKEYHNNNIPITNFQYPIIDTCGTGGDGASTFNISTAVAFVLAAAGV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCEEHHHHHHHHHHHHCCC
PVAKHGNRSASGKVGSADVLEALGIRLNAPTEKVISALSEVGITFLFAPGWHPAMKCVVP
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
LRRTLKVRTVFNLLGPLVNPLRPQAQIIGVYNSTLVKTVAQALGILGVEYAIALHGREKL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCHHHH
DEAGLGDITDIAILSHGEVKATSINPQYLGLNYAPISTLQGGDVEQNAEILKNVLQGKGT
HCCCCCCHHHEEEEECCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
SQQTDVVALNSSLALQVAGVVPLEAHQEGIGKAKDILQSGAAWLKLEQLVQFLSIF
CCCCCEEEECCCEEEEEECCCCHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNSSINEWPSLLQQLLDGQSLSSSQASNLMQGWLQEEIPPVLSGAILAALQAKGVSAQE
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHH
LAGMAKVLQSLSLTKEYHNNNIPITNFQYPIIDTCGTGGDGASTFNISTAVAFVLAAAGV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCEEHHHHHHHHHHHHCCC
PVAKHGNRSASGKVGSADVLEALGIRLNAPTEKVISALSEVGITFLFAPGWHPAMKCVVP
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
LRRTLKVRTVFNLLGPLVNPLRPQAQIIGVYNSTLVKTVAQALGILGVEYAIALHGREKL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCHHHH
DEAGLGDITDIAILSHGEVKATSINPQYLGLNYAPISTLQGGDVEQNAEILKNVLQGKGT
HCCCCCCHHHEEEEECCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
SQQTDVVALNSSLALQVAGVVPLEAHQEGIGKAKDILQSGAAWLKLEQLVQFLSIF
CCCCCEEEECCCEEEEEECCCCHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA