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The map label for this gene is asnC [H]

Identifier: 113475887

GI number: 113475887

Start: 3493145

End: 3494536

Strand: Direct

Name: asnC [H]

Synonym: Tery_2246

Alternate gene names: 113475887

Gene position: 3493145-3494536 (Clockwise)

Preceding gene: 113475886

Following gene: 113475888

Centisome position: 45.07

GC content: 37.21

Gene sequence:

>1392_bases
ATGACAAAGCAACGAATTGCAAAAATATTAGGAAGCGGTCAACCTGATGCCAAAGTAACAATTCAAGGGTGGGTACGCAC
TAAGCGAGAATTGAAAGAGTTTGCTTTTGTAGAAGTTAATGACGGTTCATGTTTAGCTAATTTGCAAGTAGTATTAAATC
CTGATCTACCAAATTATCAGGAAAGTTTGCAGCAAATGAATACAGGTGCCTCAGTAGAAATGACTGGTATTTTGGTAGAG
TCCCCAGCAAAGGGGCAAAGAATTGAATTAAAGGCAGAAAGTATTACTGCTTATGGTGATGCCGACCCTGAAACATATCC
TTTGCAGAAAAAACGTCATTCTTTTGAGTTTCTCCGCACTATTGCACATTTGCGAGGACGTACTAATACTTATGGAGCAG
TTTTTCGGGTAAGAAATACTTGTGCTAATGCCATTCATCAATTTTTTCAAGAACGAGGTTTTTTGTGGGTTCACACTCCT
ATTATTACTGCTAGTGACTGTGAAGGTGCGGGAGAAATGTTTACTGTTACTAATTTAGATTTAAAGAAAATTCCTCTCAC
AGAAAAACAAGATATTGATTTTAGTCAAGACTTTTTTGGAAAGTCGGCTTTTCTGACAGTTAGTGGTCAGTTAGAAGCAG
AAATTATGGCAACTGCTTTGAGTAATGTTTATACGTTTGGTCCGACTTTTAGAGCAGAAAATTCTAATACTTCTCGGCAT
TTAGCTGAGTTTTGGATGATTGAACCTGAGATGGCTTTTTGCGACTTGGAAGGAGATATGGATTTAGCTGAGGAATTCTT
AAAATATATTTTTAAATCTGTTTTAGAAGGTTGTCCGGAGGATATGGAATTTTTCAATAAACGGATTGATAAAACAGTTT
TTGAAACCGCGGATACAATTATTAATAATAGTTTTGAACGGATTACTTATACTGAGGCAGTTTCTTTATTAGAAAAGGCG
GATAAAAAGTTTGATTACCCGGTAGACTGGGGTTTGGATTTACAGTCAGAACATGAACGTTATTTGTGTGAGGAGTTGTT
TAAAAAACCTGTTATTGTGACTGATTATCCTGCAAAAATTAAGGCTTTTTATATGCGGTTAAATGATGACGCTAAAACAG
TTAGAGCAATGGATGTTTTAGTGCCGAAAGTAGGAGAAATTATTGGTGGTTCTCAGAGGGAAGAACGTTTAGATGTTTTG
GAGAGGCGCATAGATGAACAGGAGATGAATAAGGAAGAATTATGGTGGTATTTAGATTTGCGGAGGTATGGTACTGTCCC
TCATGCGGGGTTTGGTTTGGGATTTGAAAGAGTGGTACAGTTTATGACAGGAATGGGGAATATTCGAGATGTGATTCCTT
TTCCGAGGGCACCTCTAACTGTGGATTTTTAA

Upstream 100 bases:

>100_bases
AGGCCGGGATTTATCTCGTACTGACGCTATCCCTTGCAGGCGTAGGGCTTTTGCCGGATAAAGCTAAACTTTATAATACT
ATAAAAGCAGGATTAAATAT

Downstream 100 bases:

>100_bases
AATTATAAATTGTTGGAAAAGTAGGGGACGATATAGTTTAATTAATGGGCAAAAGTTAAAATTTAAAAGTTAAAATGTAA
AAGTCTAGTAGGGTGCTTTA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTKQRIAKILGSGQPDAKVTIQGWVRTKRELKEFAFVEVNDGSCLANLQVVLNPDLPNYQESLQQMNTGASVEMTGILVE
SPAKGQRIELKAESITAYGDADPETYPLQKKRHSFEFLRTIAHLRGRTNTYGAVFRVRNTCANAIHQFFQERGFLWVHTP
IITASDCEGAGEMFTVTNLDLKKIPLTEKQDIDFSQDFFGKSAFLTVSGQLEAEIMATALSNVYTFGPTFRAENSNTSRH
LAEFWMIEPEMAFCDLEGDMDLAEEFLKYIFKSVLEGCPEDMEFFNKRIDKTVFETADTIINNSFERITYTEAVSLLEKA
DKKFDYPVDWGLDLQSEHERYLCEELFKKPVIVTDYPAKIKAFYMRLNDDAKTVRAMDVLVPKVGEIIGGSQREERLDVL
ERRIDEQEMNKEELWWYLDLRRYGTVPHAGFGLGFERVVQFMTGMGNIRDVIPFPRAPLTVDF

Sequences:

>Translated_463_residues
MTKQRIAKILGSGQPDAKVTIQGWVRTKRELKEFAFVEVNDGSCLANLQVVLNPDLPNYQESLQQMNTGASVEMTGILVE
SPAKGQRIELKAESITAYGDADPETYPLQKKRHSFEFLRTIAHLRGRTNTYGAVFRVRNTCANAIHQFFQERGFLWVHTP
IITASDCEGAGEMFTVTNLDLKKIPLTEKQDIDFSQDFFGKSAFLTVSGQLEAEIMATALSNVYTFGPTFRAENSNTSRH
LAEFWMIEPEMAFCDLEGDMDLAEEFLKYIFKSVLEGCPEDMEFFNKRIDKTVFETADTIINNSFERITYTEAVSLLEKA
DKKFDYPVDWGLDLQSEHERYLCEELFKKPVIVTDYPAKIKAFYMRLNDDAKTVRAMDVLVPKVGEIIGGSQREERLDVL
ERRIDEQEMNKEELWWYLDLRRYGTVPHAGFGLGFERVVQFMTGMGNIRDVIPFPRAPLTVDF
>Mature_462_residues
TKQRIAKILGSGQPDAKVTIQGWVRTKRELKEFAFVEVNDGSCLANLQVVLNPDLPNYQESLQQMNTGASVEMTGILVES
PAKGQRIELKAESITAYGDADPETYPLQKKRHSFEFLRTIAHLRGRTNTYGAVFRVRNTCANAIHQFFQERGFLWVHTPI
ITASDCEGAGEMFTVTNLDLKKIPLTEKQDIDFSQDFFGKSAFLTVSGQLEAEIMATALSNVYTFGPTFRAENSNTSRHL
AEFWMIEPEMAFCDLEGDMDLAEEFLKYIFKSVLEGCPEDMEFFNKRIDKTVFETADTIINNSFERITYTEAVSLLEKAD
KKFDYPVDWGLDLQSEHERYLCEELFKKPVIVTDYPAKIKAFYMRLNDDAKTVRAMDVLVPKVGEIIGGSQREERLDVLE
RRIDEQEMNKEELWWYLDLRRYGTVPHAGFGLGFERVVQFMTGMGNIRDVIPFPRAPLTVDF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=445, Percent_Identity=47.1910112359551, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI4758762, Length=471, Percent_Identity=27.8131634819533, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI45439306, Length=341, Percent_Identity=29.3255131964809, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=57.9399141630901, Blast_Score=568, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17556372, Length=448, Percent_Identity=32.8125, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71984122, Length=469, Percent_Identity=28.997867803838, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17551876, Length=341, Percent_Identity=28.4457478005865, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=37.1549893842887, Blast_Score=301, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6321807, Length=450, Percent_Identity=29.1111111111111, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6323011, Length=342, Percent_Identity=29.8245614035088, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19922416, Length=458, Percent_Identity=35.589519650655, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI19921528, Length=458, Percent_Identity=28.6026200873362, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI17136276, Length=342, Percent_Identity=28.0701754385965, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52998; Mature: 52867

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQRIAKILGSGQPDAKVTIQGWVRTKRELKEFAFVEVNDGSCLANLQVVLNPDLPNYQ
CCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHEEEEEECCCCEEEEEEEEECCCCCCHH
ESLQQMNTGASVEMTGILVESPAKGQRIELKAESITAYGDADPETYPLQKKRHSFEFLRT
HHHHHHCCCCCEEEEEEEEECCCCCCEEEEEECEEEECCCCCCCCCCCHHHHHHHHHHHH
IAHLRGRTNTYGAVFRVRNTCANAIHQFFQERGFLWVHTPIITASDCEGAGEMFTVTNLD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCCEEEEECCC
LKKIPLTEKQDIDFSQDFFGKSAFLTVSGQLEAEIMATALSNVYTFGPTFRAENSNTSRH
EEECCCCCCCCCCCCHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEECCCCCCHHH
LAEFWMIEPEMAFCDLEGDMDLAEEFLKYIFKSVLEGCPEDMEFFNKRIDKTVFETADTI
HHHHHEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
INNSFERITYTEAVSLLEKADKKFDYPVDWGLDLQSEHERYLCEELFKKPVIVTDYPAKI
HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCHHE
KAFYMRLNDDAKTVRAMDVLVPKVGEIIGGSQREERLDVLERRIDEQEMNKEELWWYLDL
EEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCHHHEEEEEEH
RRYGTVPHAGFGLGFERVVQFMTGMGNIRDVIPFPRAPLTVDF
HHCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCEEECC
>Mature Secondary Structure 
TKQRIAKILGSGQPDAKVTIQGWVRTKRELKEFAFVEVNDGSCLANLQVVLNPDLPNYQ
CHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHEEEEEECCCCEEEEEEEEECCCCCCHH
ESLQQMNTGASVEMTGILVESPAKGQRIELKAESITAYGDADPETYPLQKKRHSFEFLRT
HHHHHHCCCCCEEEEEEEEECCCCCCEEEEEECEEEECCCCCCCCCCCHHHHHHHHHHHH
IAHLRGRTNTYGAVFRVRNTCANAIHQFFQERGFLWVHTPIITASDCEGAGEMFTVTNLD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCCEEEEECCC
LKKIPLTEKQDIDFSQDFFGKSAFLTVSGQLEAEIMATALSNVYTFGPTFRAENSNTSRH
EEECCCCCCCCCCCCHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEECCCCCCHHH
LAEFWMIEPEMAFCDLEGDMDLAEEFLKYIFKSVLEGCPEDMEFFNKRIDKTVFETADTI
HHHHHEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
INNSFERITYTEAVSLLEKADKKFDYPVDWGLDLQSEHERYLCEELFKKPVIVTDYPAKI
HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCHHE
KAFYMRLNDDAKTVRAMDVLVPKVGEIIGGSQREERLDVLERRIDEQEMNKEELWWYLDL
EEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCHHHEEEEEEH
RRYGTVPHAGFGLGFERVVQFMTGMGNIRDVIPFPRAPLTVDF
HHCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]