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The map label for this gene is queF

Identifier: 113475749

GI number: 113475749

Start: 3273185

End: 3273610

Strand: Direct

Name: queF

Synonym: Tery_2098

Alternate gene names: 113475749

Gene position: 3273185-3273610 (Clockwise)

Preceding gene: 113475747

Following gene: 113475750

Centisome position: 42.23

GC content: 32.16

Gene sequence:

>426_bases
ATGAATTACGATGAAACTAACAATGAACTATTTCAAGAGTCAAATATGCAAGAACTTAAATATGGAGAGCGGAATATATT
GGAGGGAGAGTTAATTACTTTTCCAAATCCCCGTATAGGACGACGTTATGAAATAAATATTAGTTTACCAGAATTTACTT
GTAAGTGTCCTTTTTCTGGTTATCCAGATTTTGCTACAATTCATATTAAATATATTCCCAATGAACGAGTAGTTGAGTTA
AAAGCTATAAAGTTATATATCAACAGTTATCGAGAACGCTATATTTCCCATGAAGAATCAGTTAATCAAATCTTAGATGA
CTTTGTCGCAGCTTGCGATCCTTTAGAAGTCAAAATTAAAGGTGATTTTTTGCCTCGGGGAAATGTTCATACAACTATTG
AAGTTGAACATTATAAAGCAAGCTAG

Upstream 100 bases:

>100_bases
TAATTATACCATAACACATAAATTTGTCAAGTCATAATCAAAAGAATTTACTCAGATAAATTGCATTTCCAAAGAATTGA
ATCTTGTTTAATTAATATCT

Downstream 100 bases:

>100_bases
AGAAGTAATATTACCAGGATTTTCCCAGGATAACTAAGAAACAAAGTTTATATTATTAACAACAATTTATCCGATAAACT
GGACACGGGCTACCTTATAA

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MNYDETNNELFQESNMQELKYGERNILEGELITFPNPRIGRRYEINISLPEFTCKCPFSGYPDFATIHIKYIPNERVVEL
KAIKLYINSYRERYISHEESVNQILDDFVAACDPLEVKIKGDFLPRGNVHTTIEVEHYKAS

Sequences:

>Translated_141_residues
MNYDETNNELFQESNMQELKYGERNILEGELITFPNPRIGRRYEINISLPEFTCKCPFSGYPDFATIHIKYIPNERVVEL
KAIKLYINSYRERYISHEESVNQILDDFVAACDPLEVKIKGDFLPRGNVHTTIEVEHYKAS
>Mature_141_residues
MNYDETNNELFQESNMQELKYGERNILEGELITFPNPRIGRRYEINISLPEFTCKCPFSGYPDFATIHIKYIPNERVVEL
KAIKLYINSYRERYISHEESVNQILDDFVAACDPLEVKIKGDFLPRGNVHTTIEVEHYKAS

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEF_TRIEI (Q113I7)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721810.1
- ProteinModelPortal:   Q113I7
- SMR:   Q113I7
- STRING:   Q113I7
- GeneID:   4243932
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2098
- NMPDR:   fig|203124.1.peg.2168
- eggNOG:   COG0780
- HOGENOM:   HBG294103
- OMA:   FRNAGIF
- ProtClustDB:   PRK13258
- BioCyc:   TERY203124:TERY_2098-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00818
- InterPro:   IPR016856
- InterPro:   IPR020602
- PIRSF:   PIRSF027377
- TIGRFAMs:   TIGR03139

Pfam domain/function: PF01227 GTP_cyclohydroI

EC number: =1.7.1.13

Molecular weight: Translated: 16538; Mature: 16538

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYDETNNELFQESNMQELKYGERNILEGELITFPNPRIGRRYEINISLPEFTCKCPFSG
CCCCCCCCHHHHHCCHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEECCCCC
YPDFATIHIKYIPNERVVELKAIKLYINSYRERYISHEESVNQILDDFVAACDPLEVKIK
CCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
GDFLPRGNVHTTIEVEHYKAS
CCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MNYDETNNELFQESNMQELKYGERNILEGELITFPNPRIGRRYEINISLPEFTCKCPFSG
CCCCCCCCHHHHHCCHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEECCCCC
YPDFATIHIKYIPNERVVELKAIKLYINSYRERYISHEESVNQILDDFVAACDPLEVKIK
CCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
GDFLPRGNVHTTIEVEHYKAS
CCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA