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The map label for this gene is purQ [H]

Identifier: 113475620

GI number: 113475620

Start: 3028864

End: 3029559

Strand: Direct

Name: purQ [H]

Synonym: Tery_1955

Alternate gene names: 113475620

Gene position: 3028864-3029559 (Clockwise)

Preceding gene: 113475619

Following gene: 113475623

Centisome position: 39.08

GC content: 35.92

Gene sequence:

>696_bases
ATGAAATTTGGCATTATTATTTTTCCTGGTTCAAATTGCGATCGGGATGTAGCTTGGGTAACTCAGGGGTTATTGGGTCA
ACCAACTCGCATGGTTTGGCACCAAGAAGAAGATATTTCTGATCTGGATGTAATAGTTATCCCTGGAGGCTTCAGTTATG
GAGATTATTTAAGATGTGGAGCAATTGCCCGTTTTTCTCCAGTAATGAAAGCAACTATTACCCACGCTCAAAAGGGGAAA
TTAGTTTTAGGAATATGTAATGGTTTCCAGATATTGACAGAAATAGGGTTATTGCCTGGAGTCTTGGTGCGAAATCATAA
ATTAAATTTTATTTGCAATCAAACTTATATCAGAGTAGAAAATTCTAATACTCCTTGGACATCTGCTTATAGAACAAAAG
AAATAATTAGTTTGCCAATAGCTCATGGGGAAGGTTGTTATTATGTTGATGTAGATACTTTGCAAGAATTAGAAAATAAT
CGTCAAATCTTGTTTCGTTACTGCACAAAAAATGGTGGAATTAGCCCAGAAGCTAATCCTAATGGTTCTTTAAACAATAT
TGCTGGTATCTGCAACCGTCAAGGTAATGTGTTGGCAATGATGCCTCATCCGGAAAGAGCATCAGACCCAATTTTAGGTA
ATACAGATGGCATGAAATTGTTTAAAGGGTTATTAATGGATGTAGTTAGAATATAA

Upstream 100 bases:

>100_bases
TGAAACTTTTACCATAAAATAATTAAACAGTAGATGGTTTAAAAAAACAGACAAAGCCTTCTACATTAGGGTCGGAAGAA
TGACTTAATTGAAAATTAAT

Downstream 100 bases:

>100_bases
ACTACAGTCATCTATACCAGTTGCTTTCGTTCTGAAAATAGTTAAACCTCAACGAGTCTATTTCCGATTAACCTTATATA
AGGCTCGTTGGCCTTCAAAA

Product: phosphoribosylformylglycinamidine synthase subunit I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKFGIIIFPGSNCDRDVAWVTQGLLGQPTRMVWHQEEDISDLDVIVIPGGFSYGDYLRCGAIARFSPVMKATITHAQKGK
LVLGICNGFQILTEIGLLPGVLVRNHKLNFICNQTYIRVENSNTPWTSAYRTKEIISLPIAHGEGCYYVDVDTLQELENN
RQILFRYCTKNGGISPEANPNGSLNNIAGICNRQGNVLAMMPHPERASDPILGNTDGMKLFKGLLMDVVRI

Sequences:

>Translated_231_residues
MKFGIIIFPGSNCDRDVAWVTQGLLGQPTRMVWHQEEDISDLDVIVIPGGFSYGDYLRCGAIARFSPVMKATITHAQKGK
LVLGICNGFQILTEIGLLPGVLVRNHKLNFICNQTYIRVENSNTPWTSAYRTKEIISLPIAHGEGCYYVDVDTLQELENN
RQILFRYCTKNGGISPEANPNGSLNNIAGICNRQGNVLAMMPHPERASDPILGNTDGMKLFKGLLMDVVRI
>Mature_231_residues
MKFGIIIFPGSNCDRDVAWVTQGLLGQPTRMVWHQEEDISDLDVIVIPGGFSYGDYLRCGAIARFSPVMKATITHAQKGK
LVLGICNGFQILTEIGLLPGVLVRNHKLNFICNQTYIRVENSNTPWTSAYRTKEIISLPIAHGEGCYYVDVDTLQELENN
RQILFRYCTKNGGISPEANPNGSLNNIAGICNRQGNVLAMMPHPERASDPILGNTDGMKLFKGLLMDVVRI

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=192, Percent_Identity=32.2916666666667, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI48994899, Length=184, Percent_Identity=32.6086956521739, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17553022, Length=241, Percent_Identity=25.7261410788382, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=180, Percent_Identity=30.5555555555556, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582111, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582109, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17137292, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25597; Mature: 25597

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGIIIFPGSNCDRDVAWVTQGLLGQPTRMVWHQEEDISDLDVIVIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCEEEEECCCCCCCCHHHHC
AIARFSPVMKATITHAQKGKLVLGICNGFQILTEIGLLPGVLVRNHKLNFICNQTYIRVE
CHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEECCCEEEEECCEEEEEE
NSNTPWTSAYRTKEIISLPIAHGEGCYYVDVDTLQELENNRQILFRYCTKNGGISPEANP
CCCCCCCCHHHCCEEEEEECCCCCCEEEEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCC
NGSLNNIAGICNRQGNVLAMMPHPERASDPILGNTDGMKLFKGLLMDVVRI
CCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFGIIIFPGSNCDRDVAWVTQGLLGQPTRMVWHQEEDISDLDVIVIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCEEEEECCCCCCCCHHHHC
AIARFSPVMKATITHAQKGKLVLGICNGFQILTEIGLLPGVLVRNHKLNFICNQTYIRVE
CHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEECCCEEEEECCEEEEEE
NSNTPWTSAYRTKEIISLPIAHGEGCYYVDVDTLQELENNRQILFRYCTKNGGISPEANP
CCCCCCCCHHHCCEEEEEECCCCCCEEEEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCC
NGSLNNIAGICNRQGNVLAMMPHPERASDPILGNTDGMKLFKGLLMDVVRI
CCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA