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The map label for this gene is prk [H]

Identifier: 113475513

GI number: 113475513

Start: 2829172

End: 2830107

Strand: Direct

Name: prk [H]

Synonym: Tery_1845

Alternate gene names: 113475513

Gene position: 2829172-2830107 (Clockwise)

Preceding gene: 113475512

Following gene: 113475514

Centisome position: 36.5

GC content: 41.03

Gene sequence:

>936_bases
ATGACTCATAGTCCAATAATATTAGGTGTTGTAGGTGATAGCGCTGCGGGTAAAACTACCTTAACTAGAGGAGTGGCTCA
AGTCTTAGGGCCAGAAAACGTTACAGTTATCTGTACAGACGACTACCATCGCTATGATCGAAAACAACGAGCTGAAATAG
GCATTACTGCCCTCCACCCAGACTGTAACCATCTTGATATAATTCAGCAACATCTAAGCTTGCTGAGTACCGGACAACCA
ATTCTCAAACCTATTTATAATCACTCAACCGGAAAATTTGACCCTCCAGAATATATTAAACCTAAAAAATTCGTTATTGT
TGAGGGACTATTGGGTTATTCGACTAGGGGGGCAAGAGACTGTTACCACGTGAAAGTCTACTTAGCCCCTCCAGAAAAAC
TTAGGGCAAAATGGAAAGTAAAACGGGATACGATGAAAAGGGGCTACACTGAGGCAGAAGTCCTGAAACAAATGGAAAAG
CGGGAAGCAGACTCAGACGCATTTATCCGTCCTCAACGCAAGTGGGCAGATGTAGTTGTTAGCTTCTATCCCTATTCTAG
TGATATAAATAGTTCTCAACTTAATGTCCGTTTGTTGCTTAGACCAACTATTCCCCACCCAGATTTTTTAGAAATTCTCG
ATCAAGGTAGTCCTAGTTTTCAACCTGCAGTCCGTTTGGGTTTAGACCGAGATATGGGTAAACCAGTAGATGTATTGGAA
ATTGACAGTAATGCTACTAAGGCACAGGTAAATGAGTTAGAGATAATTCTCTGCAAGGAAATGCCCCACTTAAAAGATTT
CTGCTCCCTGGAAACACATCCAGATATAGGTAAGCTAGTTGGTACAACTGGGGAGTTGCTTCAGAGTTATCCTCTAGCTT
TGACTCAATTACTTATTTCTTATCACATGATCAAGGCAACTAATATTTATCTGTAG

Upstream 100 bases:

>100_bases
AAAAACCTTGCCCCCAGTGCTAAATAAACCATAGAATTAAAGATTATTACAAATTTGAGGTTGTGCCATATAGGCCATTT
TCTGATGGGAGAACAACATT

Downstream 100 bases:

>100_bases
AATTATTATAGAAGTTTTAAGTACGAAACAGGGGTTAAAATTTCTGGCTTTTGTGAGGGGTAAAACGTCACTAAAACTTA
ACATATAATAGATGGCTAAT

Product: phosphoribulokinase

Products: NA

Alternate protein names: PRK; PRKase; Phosphopentokinase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTHSPIILGVVGDSAAGKTTLTRGVAQVLGPENVTVICTDDYHRYDRKQRAEIGITALHPDCNHLDIIQQHLSLLSTGQP
ILKPIYNHSTGKFDPPEYIKPKKFVIVEGLLGYSTRGARDCYHVKVYLAPPEKLRAKWKVKRDTMKRGYTEAEVLKQMEK
READSDAFIRPQRKWADVVVSFYPYSSDINSSQLNVRLLLRPTIPHPDFLEILDQGSPSFQPAVRLGLDRDMGKPVDVLE
IDSNATKAQVNELEIILCKEMPHLKDFCSLETHPDIGKLVGTTGELLQSYPLALTQLLISYHMIKATNIYL

Sequences:

>Translated_311_residues
MTHSPIILGVVGDSAAGKTTLTRGVAQVLGPENVTVICTDDYHRYDRKQRAEIGITALHPDCNHLDIIQQHLSLLSTGQP
ILKPIYNHSTGKFDPPEYIKPKKFVIVEGLLGYSTRGARDCYHVKVYLAPPEKLRAKWKVKRDTMKRGYTEAEVLKQMEK
READSDAFIRPQRKWADVVVSFYPYSSDINSSQLNVRLLLRPTIPHPDFLEILDQGSPSFQPAVRLGLDRDMGKPVDVLE
IDSNATKAQVNELEIILCKEMPHLKDFCSLETHPDIGKLVGTTGELLQSYPLALTQLLISYHMIKATNIYL
>Mature_310_residues
THSPIILGVVGDSAAGKTTLTRGVAQVLGPENVTVICTDDYHRYDRKQRAEIGITALHPDCNHLDIIQQHLSLLSTGQPI
LKPIYNHSTGKFDPPEYIKPKKFVIVEGLLGYSTRGARDCYHVKVYLAPPEKLRAKWKVKRDTMKRGYTEAEVLKQMEKR
EADSDAFIRPQRKWADVVVSFYPYSSDINSSQLNVRLLLRPTIPHPDFLEILDQGSPSFQPAVRLGLDRDMGKPVDVLEI
DSNATKAQVNELEIILCKEMPHLKDFCSLETHPDIGKLVGTTGELLQSYPLALTQLLISYHMIKATNIYL

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoribulokinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=189, Percent_Identity=24.8677248677249, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI301129207, Length=179, Percent_Identity=26.2569832402235, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI57863312, Length=179, Percent_Identity=26.2569832402235, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13899253, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082034, Length=187, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221458995, Length=191, Percent_Identity=27.2251308900524, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24649624, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550449, Length=182, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28573516, Length=182, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI28573514, Length=182, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI28573512, Length=182, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006082
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.19 [H]

Molecular weight: Translated: 35029; Mature: 34898

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSPIILGVVGDSAAGKTTLTRGVAQVLGPENVTVICTDDYHRYDRKQRAEIGITALHP
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEEEECC
DCNHLDIIQQHLSLLSTGQPILKPIYNHSTGKFDPPEYIKPKKFVIVEGLLGYSTRGARD
CCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHCCCCEEEEEECHHCCCCCCCCC
CYHVKVYLAPPEKLRAKWKVKRDTMKRGYTEAEVLKQMEKREADSDAFIRPQRKWADVVV
EEEEEEEECCHHHHHHHHHEHHHHHHCCCCHHHHHHHHHHHCCCCCCEECCCHHHHEEEE
SFYPYSSDINSSQLNVRLLLRPTIPHPDFLEILDQGSPSFQPAVRLGLDRDMGKPVDVLE
EEECCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCEEEE
IDSNATKAQVNELEIILCKEMPHLKDFCSLETHPDIGKLVGTTGELLQSYPLALTQLLIS
ECCCCCHHHHCCEEEEEECCCCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
YHMIKATNIYL
HHHHHHEEECC
>Mature Secondary Structure 
THSPIILGVVGDSAAGKTTLTRGVAQVLGPENVTVICTDDYHRYDRKQRAEIGITALHP
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEEEECC
DCNHLDIIQQHLSLLSTGQPILKPIYNHSTGKFDPPEYIKPKKFVIVEGLLGYSTRGARD
CCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHCCCCEEEEEECHHCCCCCCCCC
CYHVKVYLAPPEKLRAKWKVKRDTMKRGYTEAEVLKQMEKREADSDAFIRPQRKWADVVV
EEEEEEEECCHHHHHHHHHEHHHHHHCCCCHHHHHHHHHHHCCCCCCEECCCHHHHEEEE
SFYPYSSDINSSQLNVRLLLRPTIPHPDFLEILDQGSPSFQPAVRLGLDRDMGKPVDVLE
EEECCCCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCEEEE
IDSNATKAQVNELEIILCKEMPHLKDFCSLETHPDIGKLVGTTGELLQSYPLALTQLLIS
ECCCCCHHHHCCEEEEEECCCCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
YHMIKATNIYL
HHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1660882; 8905231 [H]