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The map label for this gene is trxB [H]

Identifier: 113475376

GI number: 113475376

Start: 2580918

End: 2581874

Strand: Reverse

Name: trxB [H]

Synonym: Tery_1699

Alternate gene names: 113475376

Gene position: 2581874-2580918 (Counterclockwise)

Preceding gene: 113475377

Following gene: 113475375

Centisome position: 33.31

GC content: 43.47

Gene sequence:

>957_bases
TTGGAAACTTATGAATTTGATGTAGTTATTATTGGAGGTGGCCCAGCCGGCTGTAGCTGTGCACTATATACATCTCGTGC
AGATTTAAAAACAGTAATTCTGGACAAAAACCCAGCAGTGGGGGCATTGGCGATTACCCATAAAATTGCTAACTATCCGG
GAGTAGCAGGTAATATTAGCGGGAATGCGTTGCTAGATGAGATGCGAGAGCAAGCTATCTCTTTCGGAACTAAATATCAG
CGAGCACAAGTATTTGGTATTGATGTAGAAGGGTCATTAAAAAAAGTTTATACTCCAGAAGGAACGTTTTTGGGGCGATC
TCTGGTCTTAGCTACAGGGGCAATGGGTCGCAAATCTTCTCTTCGAGGCGAATCAGAATTTCTAGGTCGGGGGGTAAGCT
ACTGTGCCACTTGTGACGGAGCATTTTTTCGCCAAAAAGAGGTCGCCGTTTATGGAGTTAATCAAGAAGCAGTTGAAGAG
GCTCAGTTCCTAACGAAATTTGTGTCTACTGTTCATTGGCTGACAAATAAAGAACCACAGCATGAAGATGCCCATGTTCA
GGTATTGCTGAGTCAACCAAATGTGAAGCATTGGAATTTTACCCGCCTGACTTCGATCCAAGGTAATGAGTCGGGGGTAA
CAAATATTTTGATGAAAACTAGAGGAGAACCGGAAGTTGCTTCCCTACAGGTAGATGGGGTGTTTGTATACCAAAGTGGA
TCGAGACCGATCACAGACTACATTAGTCCTGATATTATTTTGATCGATAATGGTGGGGTTAAAGTAGATGAGATGATGGC
AACCAATGTAGAAGGAGTTTGGGCCATTGGGGATATTCGGAATACACCTTTTCAGCAGGCAGTGGTTGCAGCTTCGGATG
GCTGTATTGCAGCAATGGCAATTGATAGGTTTCTCAATAAACGTAAGGGCATTAAGCGAGATTGGGATCATTCGTAA

Upstream 100 bases:

>100_bases
GATAGTATACTATCACTACAATACTTCCTCTCATGTGCTGAGCATATCATAATAGATGTATTTTAATCTTATAAAGTATT
ATTTTTGAGGACTATAAATT

Downstream 100 bases:

>100_bases
CTGCTGAAATCATTGTTTGACATATTGTTCCCTTAAGAATATGGAAAGCATAAACTGCTCTAACCTTTGTTAATTGAGGT
GTAGTAAATCTTAGGAATAC

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
METYEFDVVIIGGGPAGCSCALYTSRADLKTVILDKNPAVGALAITHKIANYPGVAGNISGNALLDEMREQAISFGTKYQ
RAQVFGIDVEGSLKKVYTPEGTFLGRSLVLATGAMGRKSSLRGESEFLGRGVSYCATCDGAFFRQKEVAVYGVNQEAVEE
AQFLTKFVSTVHWLTNKEPQHEDAHVQVLLSQPNVKHWNFTRLTSIQGNESGVTNILMKTRGEPEVASLQVDGVFVYQSG
SRPITDYISPDIILIDNGGVKVDEMMATNVEGVWAIGDIRNTPFQQAVVAASDGCIAAMAIDRFLNKRKGIKRDWDHS

Sequences:

>Translated_318_residues
METYEFDVVIIGGGPAGCSCALYTSRADLKTVILDKNPAVGALAITHKIANYPGVAGNISGNALLDEMREQAISFGTKYQ
RAQVFGIDVEGSLKKVYTPEGTFLGRSLVLATGAMGRKSSLRGESEFLGRGVSYCATCDGAFFRQKEVAVYGVNQEAVEE
AQFLTKFVSTVHWLTNKEPQHEDAHVQVLLSQPNVKHWNFTRLTSIQGNESGVTNILMKTRGEPEVASLQVDGVFVYQSG
SRPITDYISPDIILIDNGGVKVDEMMATNVEGVWAIGDIRNTPFQQAVVAASDGCIAAMAIDRFLNKRKGIKRDWDHS
>Mature_318_residues
METYEFDVVIIGGGPAGCSCALYTSRADLKTVILDKNPAVGALAITHKIANYPGVAGNISGNALLDEMREQAISFGTKYQ
RAQVFGIDVEGSLKKVYTPEGTFLGRSLVLATGAMGRKSSLRGESEFLGRGVSYCATCDGAFFRQKEVAVYGVNQEAVEE
AQFLTKFVSTVHWLTNKEPQHEDAHVQVLLSQPNVKHWNFTRLTSIQGNESGVTNILMKTRGEPEVASLQVDGVFVYQSG
SRPITDYISPDIILIDNGGVKVDEMMATNVEGVWAIGDIRNTPFQQAVVAASDGCIAAMAIDRFLNKRKGIKRDWDHS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=310, Percent_Identity=32.9032258064516, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI87081763, Length=309, Percent_Identity=30.0970873786408, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=32.3899371069182, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=32.807570977918, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34603; Mature: 34603

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METYEFDVVIIGGGPAGCSCALYTSRADLKTVILDKNPAVGALAITHKIANYPGVAGNIS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEHHHHCCCCCCCCCC
GNALLDEMREQAISFGTKYQRAQVFGIDVEGSLKKVYTPEGTFLGRSLVLATGAMGRKSS
CHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCC
LRGESEFLGRGVSYCATCDGAFFRQKEVAVYGVNQEAVEEAQFLTKFVSTVHWLTNKEPQ
CCCCHHHHHCCCCEEEECCCCCEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCC
HEDAHVQVLLSQPNVKHWNFTRLTSIQGNESGVTNILMKTRGEPEVASLQVDGVFVYQSG
CCCCEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHEECCCCCCEEEEEEEEEEEEECC
SRPITDYISPDIILIDNGGVKVDEMMATNVEGVWAIGDIRNTPFQQAVVAASDGCIAAMA
CCCCHHHCCCCEEEECCCCCEEHHHHHCCCCCEEEECCCCCCCHHHHEEECCCCCHHHHH
IDRFLNKRKGIKRDWDHS
HHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
METYEFDVVIIGGGPAGCSCALYTSRADLKTVILDKNPAVGALAITHKIANYPGVAGNIS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEHHHHCCCCCCCCCC
GNALLDEMREQAISFGTKYQRAQVFGIDVEGSLKKVYTPEGTFLGRSLVLATGAMGRKSS
CHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCC
LRGESEFLGRGVSYCATCDGAFFRQKEVAVYGVNQEAVEEAQFLTKFVSTVHWLTNKEPQ
CCCCHHHHHCCCCEEEECCCCCEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCC
HEDAHVQVLLSQPNVKHWNFTRLTSIQGNESGVTNILMKTRGEPEVASLQVDGVFVYQSG
CCCCEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHEECCCCCCEEEEEEEEEEEEECC
SRPITDYISPDIILIDNGGVKVDEMMATNVEGVWAIGDIRNTPFQQAVVAASDGCIAAMA
CCCCHHHCCCCEEEECCCCCEEHHHHHCCCCCEEEECCCCCCCHHHHEEECCCCCHHHHH
IDRFLNKRKGIKRDWDHS
HHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]