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The map label for this gene is hhoB [H]

Identifier: 113475314

GI number: 113475314

Start: 2481037

End: 2482254

Strand: Reverse

Name: hhoB [H]

Synonym: Tery_1624

Alternate gene names: 113475314

Gene position: 2482254-2481037 (Counterclockwise)

Preceding gene: 113475316

Following gene: 113475313

Centisome position: 32.03

GC content: 37.93

Gene sequence:

>1218_bases
ATGGCTTTATCTTTTAAACAATTAACTTTGTATTTTTCTCTGTTGTCCATTGGTACTGCTACGGGATGGTTGGGTCATCA
TTATCTCGAAGCTAATAAATGGTCAAATGACTCTGATGTAATATCTTCTGTAGTTAAGAAACAAGCACAACCATCTACTC
CAAACTCTGGAAATAACCTAGTTTCCTTTTCTCATCATAATTTTATTGCCGAAGCAGTCAAAAAAGTTGGCCCATCAGTA
GTCCGTATTGATGCAGCTAAAAAGTTAACAACTGAAGCTCCAGAAGCTTTAAAGAATCCTCTATTGAAACGTTTCTTTGG
GGAAAATTTGCCGGTTCCAGAAGAACGAACTAAGCGTGGTACTGGGTCAGGGGTAATTATTAGTTCTGATGGCCGCTTAA
TTACAAATGCTCATGTTGTTCATGGAGCAAATACGGTTAAGGTGACATTGAAAGATGGCCGGGTATTTGATGGTGTGGTT
AAAGGGGTGGACTCACTGACTGATATAGCAATAATTAAAATTGAGGCCACAGATTTACCAGAGGTATCTATTGGCAAATC
AGAACAATTAATTCCTGGACAATGGGCGATCGCTATTGGTAATCCTTTGGGTTTGGACAATACTGTAACAGTGGGAATTA
TTAGTGCTATTGGTCGCACCAGTTCTCAAGTAGGTATTCCAGATAAACGAGTTCGCTTTCTTCAGACAGATGCTGCAATT
AATCCTGGCAACTCTGGTGGGCCACTTTTGAATGATCAAGGTGAAGTAATTGGTATTAATACAGCTATTAGAGCGAATGC
TCAGGGGTTAGGGTTTGCTATTCCCATAGAAACTGCAAAAAGAATTGCTGATGAATTATTTGTCTATGGGAAAATAGAGC
ACCCATTTTTAGGTATTTCAATGGTTGATTTAACTCCTGAGGTCAAGGATGAAATTAATAGAAAACTGGATACGAAAATT
AAGGATAATCAAGGTGTAGTAATTATGAGAGTTATAGAAGATTCTCCTGCACAAAAAGCTGGTTTACGTCAAGGAGATGT
GATTCAAAAAGTAGGGGGAGTAGTAGTGAAAAGTCCAACAGAAGTTCAACAAGAAGTAGAAAAAAGTTTAGTAGGAAAAA
ATTTGGCAGTGGAGGTAATTCGTAATCGGAAAATTGCCAAAATTTTGGTTAAACCTGATGCTTTTCCTGAACCACTTGAG
TTAGAACTAAAGGAATAG

Upstream 100 bases:

>100_bases
TTAAGTAATTTTTTTTGTTCATGGGAATGTGGTCAAAGCAGCCCCCTTCCCCTCCCTTGTCCCAATATTTAAAAATAGAA
TTATCTAGTAGGAAAAACAA

Downstream 100 bases:

>100_bases
AATTTATAATTGAGAAGTTAGAAGTTAGAGCTCAGAGCTTGGTATTAGAACTCAGAAGTTTTTTTTAGTAATTGGTATGA
GTAAGTAACTTTATAATACT

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MALSFKQLTLYFSLLSIGTATGWLGHHYLEANKWSNDSDVISSVVKKQAQPSTPNSGNNLVSFSHHNFIAEAVKKVGPSV
VRIDAAKKLTTEAPEALKNPLLKRFFGENLPVPEERTKRGTGSGVIISSDGRLITNAHVVHGANTVKVTLKDGRVFDGVV
KGVDSLTDIAIIKIEATDLPEVSIGKSEQLIPGQWAIAIGNPLGLDNTVTVGIISAIGRTSSQVGIPDKRVRFLQTDAAI
NPGNSGGPLLNDQGEVIGINTAIRANAQGLGFAIPIETAKRIADELFVYGKIEHPFLGISMVDLTPEVKDEINRKLDTKI
KDNQGVVIMRVIEDSPAQKAGLRQGDVIQKVGGVVVKSPTEVQQEVEKSLVGKNLAVEVIRNRKIAKILVKPDAFPEPLE
LELKE

Sequences:

>Translated_405_residues
MALSFKQLTLYFSLLSIGTATGWLGHHYLEANKWSNDSDVISSVVKKQAQPSTPNSGNNLVSFSHHNFIAEAVKKVGPSV
VRIDAAKKLTTEAPEALKNPLLKRFFGENLPVPEERTKRGTGSGVIISSDGRLITNAHVVHGANTVKVTLKDGRVFDGVV
KGVDSLTDIAIIKIEATDLPEVSIGKSEQLIPGQWAIAIGNPLGLDNTVTVGIISAIGRTSSQVGIPDKRVRFLQTDAAI
NPGNSGGPLLNDQGEVIGINTAIRANAQGLGFAIPIETAKRIADELFVYGKIEHPFLGISMVDLTPEVKDEINRKLDTKI
KDNQGVVIMRVIEDSPAQKAGLRQGDVIQKVGGVVVKSPTEVQQEVEKSLVGKNLAVEVIRNRKIAKILVKPDAFPEPLE
LELKE
>Mature_404_residues
ALSFKQLTLYFSLLSIGTATGWLGHHYLEANKWSNDSDVISSVVKKQAQPSTPNSGNNLVSFSHHNFIAEAVKKVGPSVV
RIDAAKKLTTEAPEALKNPLLKRFFGENLPVPEERTKRGTGSGVIISSDGRLITNAHVVHGANTVKVTLKDGRVFDGVVK
GVDSLTDIAIIKIEATDLPEVSIGKSEQLIPGQWAIAIGNPLGLDNTVTVGIISAIGRTSSQVGIPDKRVRFLQTDAAIN
PGNSGGPLLNDQGEVIGINTAIRANAQGLGFAIPIETAKRIADELFVYGKIEHPFLGISMVDLTPEVKDEINRKLDTKIK
DNQGVVIMRVIEDSPAQKAGLRQGDVIQKVGGVVVKSPTEVQQEVEKSLVGKNLAVEVIRNRKIAKILVKPDAFPEPLEL
ELKE

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=314, Percent_Identity=38.8535031847134, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI22129776, Length=325, Percent_Identity=38.4615384615385, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI7019477, Length=342, Percent_Identity=34.5029239766082, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI24308541, Length=335, Percent_Identity=34.9253731343284, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1789629, Length=332, Percent_Identity=36.4457831325301, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786356, Length=343, Percent_Identity=36.1516034985423, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789630, Length=286, Percent_Identity=39.1608391608392, Blast_Score=162, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24646839, Length=339, Percent_Identity=33.9233038348083, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 43563; Mature: 43431

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSFKQLTLYFSLLSIGTATGWLGHHYLEANKWSNDSDVISSVVKKQAQPSTPNSGNNL
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
VSFSHHNFIAEAVKKVGPSVVRIDAAKKLTTEAPEALKNPLLKRFFGENLPVPEERTKRG
EEECCHHHHHHHHHHCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHCCC
TGSGVIISSDGRLITNAHVVHGANTVKVTLKDGRVFDGVVKGVDSLTDIAIIKIEATDLP
CCCEEEEECCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCC
EVSIGKSEQLIPGQWAIAIGNPLGLDNTVTVGIISAIGRTSSQVGIPDKRVRFLQTDAAI
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEEEEEECCCC
NPGNSGGPLLNDQGEVIGINTAIRANAQGLGFAIPIETAKRIADELFVYGKIEHPFLGIS
CCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHEEEEEECCCEEEEE
MVDLTPEVKDEINRKLDTKIKDNQGVVIMRVIEDSPAQKAGLRQGDVIQKVGGVVVKSPT
EEECCHHHHHHHHHHHCCCEECCCCEEEEEEECCCCHHHHCCCCCHHHHHHCCEEEECCH
EVQQEVEKSLVGKNLAVEVIRNRKIAKILVKPDAFPEPLELELKE
HHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCCCCEEECC
>Mature Secondary Structure 
ALSFKQLTLYFSLLSIGTATGWLGHHYLEANKWSNDSDVISSVVKKQAQPSTPNSGNNL
CCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
VSFSHHNFIAEAVKKVGPSVVRIDAAKKLTTEAPEALKNPLLKRFFGENLPVPEERTKRG
EEECCHHHHHHHHHHCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHCCC
TGSGVIISSDGRLITNAHVVHGANTVKVTLKDGRVFDGVVKGVDSLTDIAIIKIEATDLP
CCCEEEEECCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCC
EVSIGKSEQLIPGQWAIAIGNPLGLDNTVTVGIISAIGRTSSQVGIPDKRVRFLQTDAAI
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEEEEEECCCC
NPGNSGGPLLNDQGEVIGINTAIRANAQGLGFAIPIETAKRIADELFVYGKIEHPFLGIS
CCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHEEEEEECCCEEEEE
MVDLTPEVKDEINRKLDTKIKDNQGVVIMRVIEDSPAQKAGLRQGDVIQKVGGVVVKSPT
EEECCHHHHHHHHHHHCCCEECCCCEEEEEEECCCCHHHHCCCCCHHHHHHCCEEEECCH
EVQQEVEKSLVGKNLAVEVIRNRKIAKILVKPDAFPEPLELELKE
HHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]