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The map label for this gene is rnhA

Identifier: 113475276

GI number: 113475276

Start: 2422567

End: 2423040

Strand: Reverse

Name: rnhA

Synonym: Tery_1584

Alternate gene names: 113475276

Gene position: 2423040-2422567 (Counterclockwise)

Preceding gene: 113475278

Following gene: 113475274

Centisome position: 31.26

GC content: 34.39

Gene sequence:

>474_bases
ATGACAGAAAAAAGAACCGAAATTACTATCTATACTGATGGTGCTTGTAGTGGAAATCCCGGCCCTGGTGGTTATGGTAT
AATTATTTTATCTGAGAAAAAACGCCAAGAATTATCTGGAGGTTATAAATTAACCACTAATAATCGTATGGAATTAATGG
CAGTAATAGTAGGATTAGAACAACTAGAAATTCCATCAATTGTCAATTTATATACTGACTCTAAATATATAGTTGATGCT
GTTACAAAAGGTTGGGCAAAACGTTGGCGAGCTAACAGTTGGAAACGGAATAAAAAAGATAAAGCAATGAACCCCGATCT
ATGGGGAAAATTATTAGATTTATGCAGTAAACATCAAGTTGAATTTTCTTGGGTACGGGGTCATTCTGGAAATATAGAAA
ATGAACGCTGTGATAAATTAGCGGTCAAAGCTTCTCAAAAACTTGATTTACCCTCAGACCTTGGTTATCAATAA

Upstream 100 bases:

>100_bases
TTTTTCTGAAATAATTTGTCATCTTTTCCTTTACGTGCTTAAATACTATATTACTCCCTTCTTCTTTAGAAGAAACTTAC
CGTAATAATAAGTAACTAAA

Downstream 100 bases:

>100_bases
ATCAAATTATGGGAGTTATAATTAAATAAAACTTTGTTTCTATAAAAAAATTGAATTATAGCAATAACCCTATTGATTAT
TATTGAAAAATACCAAATTC

Product: RNase HI

Products: NA

Alternate protein names: RNase H

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MTEKRTEITIYTDGACSGNPGPGGYGIIILSEKKRQELSGGYKLTTNNRMELMAVIVGLEQLEIPSIVNLYTDSKYIVDA
VTKGWAKRWRANSWKRNKKDKAMNPDLWGKLLDLCSKHQVEFSWVRGHSGNIENERCDKLAVKASQKLDLPSDLGYQ

Sequences:

>Translated_157_residues
MTEKRTEITIYTDGACSGNPGPGGYGIIILSEKKRQELSGGYKLTTNNRMELMAVIVGLEQLEIPSIVNLYTDSKYIVDA
VTKGWAKRWRANSWKRNKKDKAMNPDLWGKLLDLCSKHQVEFSWVRGHSGNIENERCDKLAVKASQKLDLPSDLGYQ
>Mature_156_residues
TEKRTEITIYTDGACSGNPGPGGYGIIILSEKKRQELSGGYKLTTNNRMELMAVIVGLEQLEIPSIVNLYTDSKYIVDAV
TKGWAKRWRANSWKRNKKDKAMNPDLWGKLLDLCSKHQVEFSWVRGHSGNIENERCDKLAVKASQKLDLPSDLGYQ

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain

Homologues:

Organism=Homo sapiens, GI21359816, Length=145, Percent_Identity=30.3448275862069, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1786408, Length=151, Percent_Identity=47.0198675496689, Blast_Score=142, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI115532542, Length=143, Percent_Identity=34.965034965035, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH_TRIEI (Q115G0)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721337.1
- ProteinModelPortal:   Q115G0
- STRING:   Q115G0
- GeneID:   4242733
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_1584
- NMPDR:   fig|203124.1.peg.5692
- eggNOG:   COG0328
- HOGENOM:   HBG742437
- OMA:   NGWRTAD
- PhylomeDB:   Q115G0
- BioCyc:   TERY203124:TERY_1584-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00042
- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156

Pfam domain/function: PF00075 RnaseH; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 17720; Mature: 17589

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKRTEITIYTDGACSGNPGPGGYGIIILSEKKRQELSGGYKLTTNNRMELMAVIVGLE
CCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHCCCEEEECCCCHHHHHHHHHHH
QLEIPSIVNLYTDSKYIVDAVTKGWAKRWRANSWKRNKKDKAMNPDLWGKLLDLCSKHQV
HCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
EFSWVRGHSGNIENERCDKLAVKASQKLDLPSDLGYQ
EEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TEKRTEITIYTDGACSGNPGPGGYGIIILSEKKRQELSGGYKLTTNNRMELMAVIVGLE
CCCCEEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHCCCEEEECCCCHHHHHHHHHHH
QLEIPSIVNLYTDSKYIVDAVTKGWAKRWRANSWKRNKKDKAMNPDLWGKLLDLCSKHQV
HCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
EFSWVRGHSGNIENERCDKLAVKASQKLDLPSDLGYQ
EEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA