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The map label for this gene is hyaD [H]

Identifier: 113474697

GI number: 113474697

Start: 1403156

End: 1404088

Strand: Direct

Name: hyaD [H]

Synonym: Tery_0883

Alternate gene names: 113474697

Gene position: 1403156-1404088 (Clockwise)

Preceding gene: 113474695

Following gene: 113474698

Centisome position: 18.1

GC content: 33.33

Gene sequence:

>933_bases
ATGTTTTTTAGTATAATTATTCCCACTTATAATCGCCTGGGAATTTTAGAAAAATGCCTCCGTGCCCTAGAAAGTCAAAC
TTATGAACAACACATAACCGAATATGAAGTAATAGTTGTCGATGATGGTTCAACAGATGATACTATCCCCTGGCTAAAAG
CTAATGCCACAGAATTTCCCCATCTCCAACTTTGGCCTCAGTCTCACCAGGGACCAGCAGCAGCCAGAAATTTAGGAGTT
GAAGTAGCTAGGGGAAATTTTATTATTTTTATAGATAGTGACTTAGTAGTAACAGATAATTTTCTTCAGGCCCATGCAAA
TACTTTAATTAAATATGGCAAAAAATCAAACTGTATCTTTACTTATGGCAGAGTAATTAATACTTGTAATTTTGATTTTC
CCACTTTAGAACCATTAAAATTGACGGATTTTTCAGCAGCTTTTTTTGCTACTGGAAATGTAGCGATCGCTCGTCATTGG
TTAATTGAAGCTGGATTATTTGATACTAATTTTAACCAGTATGGTTGGGAAGATTTAGAGTTAGGAATTAGGCTAAAAAA
ATTAGGTTTAAAATTAATTAAATGCTCAGAAGCAGTAGGTTATCATTGGCATCCACCCTTTTCTTTGGAGCAATTGCCAA
GAATGATTGACAGAGAAATTCAAAGAGGAAAAATGGGAGTTTTATTCTATCAAAAACATCCTATATTGGAAGTAAAAATT
ATGATTCAAATGACTTATTTCCACAAGTTATTATGGGGAGTTTTATCACTAGGTGGGAGACTAAATGAGAAAACAATGGC
AGTTTTTTTACAATGGTTAATTGACCGAGGTAAATCACAATTGGCTTTAGAAATTTCTCGAATATTTTTGAATTGGTATA
ATGTCAAAGCTGTTTATAGTGCTTATGCTAATATTGATGGTTTTAGGAAGTAA

Upstream 100 bases:

>100_bases
GTTTTTCCTTTTCTCCAAGAAGAAAAATTATCATGCCCCCATATCTTTCACTAAGGACCCAAGTAGCACTACCCAGGATT
GAATATAAATAACTGACTCT

Downstream 100 bases:

>100_bases
TACTATTTCTCAATCATTTATGCTATTCTACTGAGAAGTTGTATAATATAATCCCATCTCAATAGCAATTATTTTCTCCT
AGCTTATCAAACCCAAACCA

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-beta-N-acetylglucosaminyltransferase; UDP-GlcNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MFFSIIIPTYNRLGILEKCLRALESQTYEQHITEYEVIVVDDGSTDDTIPWLKANATEFPHLQLWPQSHQGPAAARNLGV
EVARGNFIIFIDSDLVVTDNFLQAHANTLIKYGKKSNCIFTYGRVINTCNFDFPTLEPLKLTDFSAAFFATGNVAIARHW
LIEAGLFDTNFNQYGWEDLELGIRLKKLGLKLIKCSEAVGYHWHPPFSLEQLPRMIDREIQRGKMGVLFYQKHPILEVKI
MIQMTYFHKLLWGVLSLGGRLNEKTMAVFLQWLIDRGKSQLALEISRIFLNWYNVKAVYSAYANIDGFRK

Sequences:

>Translated_310_residues
MFFSIIIPTYNRLGILEKCLRALESQTYEQHITEYEVIVVDDGSTDDTIPWLKANATEFPHLQLWPQSHQGPAAARNLGV
EVARGNFIIFIDSDLVVTDNFLQAHANTLIKYGKKSNCIFTYGRVINTCNFDFPTLEPLKLTDFSAAFFATGNVAIARHW
LIEAGLFDTNFNQYGWEDLELGIRLKKLGLKLIKCSEAVGYHWHPPFSLEQLPRMIDREIQRGKMGVLFYQKHPILEVKI
MIQMTYFHKLLWGVLSLGGRLNEKTMAVFLQWLIDRGKSQLALEISRIFLNWYNVKAVYSAYANIDGFRK
>Mature_310_residues
MFFSIIIPTYNRLGILEKCLRALESQTYEQHITEYEVIVVDDGSTDDTIPWLKANATEFPHLQLWPQSHQGPAAARNLGV
EVARGNFIIFIDSDLVVTDNFLQAHANTLIKYGKKSNCIFTYGRVINTCNFDFPTLEPLKLTDFSAAFFATGNVAIARHW
LIEAGLFDTNFNQYGWEDLELGIRLKKLGLKLIKCSEAVGYHWHPPFSLEQLPRMIDREIQRGKMGVLFYQKHPILEVKI
MIQMTYFHKLLWGVLSLGGRLNEKTMAVFLQWLIDRGKSQLALEISRIFLNWYNVKAVYSAYANIDGFRK

Specific function: Catalyzes the polymerization of hyaluronan, a polysaccharide composed of a repeating disaccharide of N- acetylglucosamine (GlcNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)-GlcNAc [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790044, Length=92, Percent_Identity=39.1304347826087, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.212; =2.4.1.226 [H]

Molecular weight: Translated: 35689; Mature: 35689

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFSIIIPTYNRLGILEKCLRALESQTYEQHITEYEVIVVDDGSTDDTIPWLKANATEFP
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEECCCCCCC
HLQLWPQSHQGPAAARNLGVEVARGNFIIFIDSDLVVTDNFLQAHANTLIKYGKKSNCIF
EEEECCCCCCCCHHHHHCCEEEECCCEEEEECCCEEEEHHHHHHHHHHHHHCCCCCCEEE
TYGRVINTCNFDFPTLEPLKLTDFSAAFFATGNVAIARHWLIEAGLFDTNFNQYGWEDLE
EECCCHHCCCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHCCCCEECCCCCCCCCHHH
LGIRLKKLGLKLIKCSEAVGYHWHPPFSLEQLPRMIDREIQRGKMGVLFYQKHPILEVKI
HCEEEHHHCCEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEE
MIQMTYFHKLLWGVLSLGGRLNEKTMAVFLQWLIDRGKSQLALEISRIFLNWYNVKAVYS
EEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AYANIDGFRK
HHHCCCCCCC
>Mature Secondary Structure
MFFSIIIPTYNRLGILEKCLRALESQTYEQHITEYEVIVVDDGSTDDTIPWLKANATEFP
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEECCCCCCC
HLQLWPQSHQGPAAARNLGVEVARGNFIIFIDSDLVVTDNFLQAHANTLIKYGKKSNCIF
EEEECCCCCCCCHHHHHCCEEEECCCEEEEECCCEEEEHHHHHHHHHHHHHCCCCCCEEE
TYGRVINTCNFDFPTLEPLKLTDFSAAFFATGNVAIARHWLIEAGLFDTNFNQYGWEDLE
EECCCHHCCCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHCCCCEECCCCCCCCCHHH
LGIRLKKLGLKLIKCSEAVGYHWHPPFSLEQLPRMIDREIQRGKMGVLFYQKHPILEVKI
HCEEEHHHCCEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEE
MIQMTYFHKLLWGVLSLGGRLNEKTMAVFLQWLIDRGKSQLALEISRIFLNWYNVKAVYS
EEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AYANIDGFRK
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9770287; 9525958; 10873488 [H]