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The map label for this gene is hypF [H]

Identifier: 113474623

GI number: 113474623

Start: 1258410

End: 1260767

Strand: Direct

Name: hypF [H]

Synonym: Tery_0792

Alternate gene names: 113474623

Gene position: 1258410-1260767 (Clockwise)

Preceding gene: 113474622

Following gene: 113474624

Centisome position: 16.24

GC content: 38.63

Gene sequence:

>2358_bases
ATGTCTAAAATAGCAGAACAAATTCGTATCTATGGCACTGTCCAAGGTGTAGGTTTTCGCCCTACAGTCTACCGCATTGC
TAAAACATTAGGGTTGTGCGGTGAAGTTAGTAATGATGGGCAAGGTGTTTTAATTAAAGTTGTAGGCGATCGCTCGACTA
TTGACCAGTTGATCGAAAAAATACATTCTGAACGCCCTCCACTTGCCGATATCGAAACCATTACCCGACAGCACTTGGAA
AATGCAAATTTCCTAGATTTTATCATTACCTCAAGCAACAACAACAGCGTTCGTACCAAAATAGCACCCGATGCTGCAAC
CTGCTCCAACTGCAAACATGAAATCCTTGACCCTTTGAGTCGTTGGTATCGCTACCCATTTACTAACTGTACCCACTGCG
GACCCCGCTTCAGTATTACTAAAAAATTACCTTATGATCGCAAAAATACAACTATGGCAGATTTTAACTTTTGCCCAGAA
TGTCAGGAAGAATATTCCGATCCCCTTAACCGTCGCTTCCACGCTCAACCTATTGCCTGTCATGTTTGTGGACCGAAAGC
TTGGTTAGAAAGAGCAGATGGTAAACCAGTCACTGCTGATATGTTCTCAATGTTAGATGATGTGGATGCGCTCTGTACTC
TGATCCAACGAGGAATGATAGTTGCTGTCAAAGGCTTAGGTGGCTTTCACCTTGCTTGCGATGCCACTAATGAGGAAGCG
GTACAAAAATTACGTTATCGCAAACGTCGCCCAGATAAACCTTTAGCATTGATGGCACGAGATATTGAGGTGATTTCCGA
ATATTGTAGTATTAGTGAGATGGAACACAAATTATTATCAAGTGTAGCTGCTCCTATTGTGTTGTTATCTGCCAACGGTA
GCAAACAGGTTGCTCCTAGTGTTGCACCTGGACAAAATACTTTGGGTTTTATGCTACCATATACTCCATTGCATCATTTA
GCACTGCGTCGTTTGAATGTTCCCATGGTATTAACAAGTGGCAATTTTTCTGATGAACCTCAGTGTATTGATAATGAAGA
AACTCGGGAAAAACTATCAGGAATTGCTGATTATTTTCTCATACATAATCGCCCTATTTTTAATCGGGTTGATGATTCTG
TGGTACGAGTTATTAAAGAAGTGCCTCAAGTATTACGTCGAGCTCGTGGTTATGCTCCTGCCCCAATTAATTTACCTCCT
GGATTTGCTAATATTTCTCCTATTTTGGCAATGGGAAGTCAGTTAAAAAATACTTTTTGTTTATTGCGTGATGGTCAAGC
TATTTTATCTCAACATATTGGGGATTTAAAAAATAGTTTAGCTGTCACGGCTTATCAAAAAACTTTGAATCTTTTTTTGG
AGTTATTGGAGGCTAAACCTAGTAATATTGTTGTTGATAAACACCCAGAATATTTATCAACAAAACTAGGAAAAGATTTG
GCAAATACTAATAATTCAAAAATTATAGAAGTGCAGCATCATCATAGTCATATAGCAGCTTGTATGGTTGAAAATGGATT
AGATATTGATTGTCAGCCTGTTTTAGGAATTGCTCTAGACGGGTTGGGTTATGGGGAAGATGGAACTATTTGGGGAGGAG
AATTTTTATTAGCAAATTATCACGGTTTTGAACGTTTAGGAACTTTTAAACCTGTAGCAATGATTGGAGGAGAACAGGCA
ATTTATCAACCTTGGCGGAATACTTATGCACATTTAGTAGCTGCTTTTGGTGTAGATTTTATTAAGAATTATGAATGTTT
GGAATTATTTAGTTTTTTGCAAACAAAACCTCTAGCTTTGCTAAATCAAATGATAGAAAAAAAGATTAATTCTCCCCTGG
CTTCTTCTTGTGGACGGTTATTTGATGCGGTAGCTGCTGCGATTGGAATTTGCCAAGAATCTTGTAGTTATGAAGGCCAA
GCTGCTATCAGTTTGGAGACTTTAGCAACAGAATATTTGTTAAATGATTCTGAAGAAATTGAGAGTTATCAATTGGATCT
GTTACAAATGGAAAATGTAAGTAAATTCCCTCTTACTTATATAGTGCCACAGCCAATGTGGCAATCTTTACTGATAGATA
CAAAACAAAGTGCCACTCCAGCTCTGATGGCAGCTAAATTTCATCAAGGGTTAGCGAAGGCTATTTCTAAGATGGTAGCT
GAATTACATCAGAGTTGTGAGTTTAATCAGGTAGCTTTGACTGGTGGAGTATTTCAAAATCAATTGTTACTTTCTCTAGT
GAGCGATCGCTTAATTAAAATGGGGTTAGACGTATTGACTCATCGTCAAGTTCCAGCTAATGATGGTGGTTTATCTCTAG
GTCAAGTAGCGATCGCTGCGGCTAGACTGAGAATGTAA

Upstream 100 bases:

>100_bases
TTATGAACTAATGTTACAACCAAAACCCTTGAGGAGCATCCCTATTACCGAATTGATTTCCCTTGTATAATTAATTAAGA
ATCTCAATTATTATTATCCA

Downstream 100 bases:

>100_bases
AATCAGAGGGACAAGACAAGGAGGAAAAAACAAGGAGTCGTGGACAGATCGAGGAATTTTAAACAATTTTGATTTTAGTC
AAAGTTTGATTAATTTATTT

Product: (NiFe) hydrogenase maturation protein HypF

Products: NA

Alternate protein names: Carbamoyl phosphate-converting enzyme hypF; [NiFe]-hydrogenase maturation factor hypF; Hydrogenase maturation protein hypF [H]

Number of amino acids: Translated: 785; Mature: 784

Protein sequence:

>785_residues
MSKIAEQIRIYGTVQGVGFRPTVYRIAKTLGLCGEVSNDGQGVLIKVVGDRSTIDQLIEKIHSERPPLADIETITRQHLE
NANFLDFIITSSNNNSVRTKIAPDAATCSNCKHEILDPLSRWYRYPFTNCTHCGPRFSITKKLPYDRKNTTMADFNFCPE
CQEEYSDPLNRRFHAQPIACHVCGPKAWLERADGKPVTADMFSMLDDVDALCTLIQRGMIVAVKGLGGFHLACDATNEEA
VQKLRYRKRRPDKPLALMARDIEVISEYCSISEMEHKLLSSVAAPIVLLSANGSKQVAPSVAPGQNTLGFMLPYTPLHHL
ALRRLNVPMVLTSGNFSDEPQCIDNEETREKLSGIADYFLIHNRPIFNRVDDSVVRVIKEVPQVLRRARGYAPAPINLPP
GFANISPILAMGSQLKNTFCLLRDGQAILSQHIGDLKNSLAVTAYQKTLNLFLELLEAKPSNIVVDKHPEYLSTKLGKDL
ANTNNSKIIEVQHHHSHIAACMVENGLDIDCQPVLGIALDGLGYGEDGTIWGGEFLLANYHGFERLGTFKPVAMIGGEQA
IYQPWRNTYAHLVAAFGVDFIKNYECLELFSFLQTKPLALLNQMIEKKINSPLASSCGRLFDAVAAAIGICQESCSYEGQ
AAISLETLATEYLLNDSEEIESYQLDLLQMENVSKFPLTYIVPQPMWQSLLIDTKQSATPALMAAKFHQGLAKAISKMVA
ELHQSCEFNQVALTGGVFQNQLLLSLVSDRLIKMGLDVLTHRQVPANDGGLSLGQVAIAAARLRM

Sequences:

>Translated_785_residues
MSKIAEQIRIYGTVQGVGFRPTVYRIAKTLGLCGEVSNDGQGVLIKVVGDRSTIDQLIEKIHSERPPLADIETITRQHLE
NANFLDFIITSSNNNSVRTKIAPDAATCSNCKHEILDPLSRWYRYPFTNCTHCGPRFSITKKLPYDRKNTTMADFNFCPE
CQEEYSDPLNRRFHAQPIACHVCGPKAWLERADGKPVTADMFSMLDDVDALCTLIQRGMIVAVKGLGGFHLACDATNEEA
VQKLRYRKRRPDKPLALMARDIEVISEYCSISEMEHKLLSSVAAPIVLLSANGSKQVAPSVAPGQNTLGFMLPYTPLHHL
ALRRLNVPMVLTSGNFSDEPQCIDNEETREKLSGIADYFLIHNRPIFNRVDDSVVRVIKEVPQVLRRARGYAPAPINLPP
GFANISPILAMGSQLKNTFCLLRDGQAILSQHIGDLKNSLAVTAYQKTLNLFLELLEAKPSNIVVDKHPEYLSTKLGKDL
ANTNNSKIIEVQHHHSHIAACMVENGLDIDCQPVLGIALDGLGYGEDGTIWGGEFLLANYHGFERLGTFKPVAMIGGEQA
IYQPWRNTYAHLVAAFGVDFIKNYECLELFSFLQTKPLALLNQMIEKKINSPLASSCGRLFDAVAAAIGICQESCSYEGQ
AAISLETLATEYLLNDSEEIESYQLDLLQMENVSKFPLTYIVPQPMWQSLLIDTKQSATPALMAAKFHQGLAKAISKMVA
ELHQSCEFNQVALTGGVFQNQLLLSLVSDRLIKMGLDVLTHRQVPANDGGLSLGQVAIAAARLRM
>Mature_784_residues
SKIAEQIRIYGTVQGVGFRPTVYRIAKTLGLCGEVSNDGQGVLIKVVGDRSTIDQLIEKIHSERPPLADIETITRQHLEN
ANFLDFIITSSNNNSVRTKIAPDAATCSNCKHEILDPLSRWYRYPFTNCTHCGPRFSITKKLPYDRKNTTMADFNFCPEC
QEEYSDPLNRRFHAQPIACHVCGPKAWLERADGKPVTADMFSMLDDVDALCTLIQRGMIVAVKGLGGFHLACDATNEEAV
QKLRYRKRRPDKPLALMARDIEVISEYCSISEMEHKLLSSVAAPIVLLSANGSKQVAPSVAPGQNTLGFMLPYTPLHHLA
LRRLNVPMVLTSGNFSDEPQCIDNEETREKLSGIADYFLIHNRPIFNRVDDSVVRVIKEVPQVLRRARGYAPAPINLPPG
FANISPILAMGSQLKNTFCLLRDGQAILSQHIGDLKNSLAVTAYQKTLNLFLELLEAKPSNIVVDKHPEYLSTKLGKDLA
NTNNSKIIEVQHHHSHIAACMVENGLDIDCQPVLGIALDGLGYGEDGTIWGGEFLLANYHGFERLGTFKPVAMIGGEQAI
YQPWRNTYAHLVAAFGVDFIKNYECLELFSFLQTKPLALLNQMIEKKINSPLASSCGRLFDAVAAAIGICQESCSYEGQA
AISLETLATEYLLNDSEEIESYQLDLLQMENVSKFPLTYIVPQPMWQSLLIDTKQSATPALMAAKFHQGLAKAISKMVAE
LHQSCEFNQVALTGGVFQNQLLLSLVSDRLIKMGLDVLTHRQVPANDGGLSLGQVAIAAARLRM

Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb

COG id: COG0068

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367152, Length=778, Percent_Identity=41.5167095115681, Blast_Score=533, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001792
- InterPro:   IPR017968
- InterPro:   IPR004421
- InterPro:   IPR017945
- InterPro:   IPR006070
- InterPro:   IPR011125 [H]

Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]

EC number: NA

Molecular weight: Translated: 86854; Mature: 86723

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAEQIRIYGTVQGVGFRPTVYRIAKTLGLCGEVSNDGQGVLIKVVGDRSTIDQLIEK
CCHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHH
IHSERPPLADIETITRQHLENANFLDFIITSSNNNSVRTKIAPDAATCSNCKHEILDPLS
HHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHHHHCCHHHHHHHHH
RWYRYPFTNCTHCGPRFSITKKLPYDRKNTTMADFNFCPECQEEYSDPLNRRFHAQPIAC
HHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHCCHHHCCCCCCCEEE
HVCGPKAWLERADGKPVTADMFSMLDDVDALCTLIQRGMIVAVKGLGGFHLACDATNEEA
EECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCHHH
VQKLRYRKRRPDKPLALMARDIEVISEYCSISEMEHKLLSSVAAPIVLLSANGSKQVAPS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
VAPGQNTLGFMLPYTPLHHLALRRLNVPMVLTSGNFSDEPQCIDNEETREKLSGIADYFL
CCCCCCCCEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
IHNRPIFNRVDDSVVRVIKEVPQVLRRARGYAPAPINLPPGFANISPILAMGSQLKNTFC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEE
LLRDGQAILSQHIGDLKNSLAVTAYQKTLNLFLELLEAKPSNIVVDKHPEYLSTKLGKDL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
ANTNNSKIIEVQHHHSHIAACMVENGLDIDCQPVLGIALDGLGYGEDGTIWGGEFLLANY
HCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHEEECCCCCCCCCCEECCEEEEECC
HGFERLGTFKPVAMIGGEQAIYQPWRNTYAHLVAAFGVDFIKNYECLELFSFLQTKPLAL
CCHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
LNQMIEKKINSPLASSCGRLFDAVAAAIGICQESCSYEGQAAISLETLATEYLLNDSEEI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCHHHH
ESYQLDLLQMENVSKFPLTYIVPQPMWQSLLIDTKQSATPALMAAKFHQGLAKAISKMVA
HHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELHQSCEFNQVALTGGVFQNQLLLSLVSDRLIKMGLDVLTHRQVPANDGGLSLGQVAIAA
HHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
ARLRM
HHHCC
>Mature Secondary Structure 
SKIAEQIRIYGTVQGVGFRPTVYRIAKTLGLCGEVSNDGQGVLIKVVGDRSTIDQLIEK
CHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHH
IHSERPPLADIETITRQHLENANFLDFIITSSNNNSVRTKIAPDAATCSNCKHEILDPLS
HHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHHHHCCHHHHHHHHH
RWYRYPFTNCTHCGPRFSITKKLPYDRKNTTMADFNFCPECQEEYSDPLNRRFHAQPIAC
HHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHCCHHHCCCCCCCEEE
HVCGPKAWLERADGKPVTADMFSMLDDVDALCTLIQRGMIVAVKGLGGFHLACDATNEEA
EECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCHHH
VQKLRYRKRRPDKPLALMARDIEVISEYCSISEMEHKLLSSVAAPIVLLSANGSKQVAPS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
VAPGQNTLGFMLPYTPLHHLALRRLNVPMVLTSGNFSDEPQCIDNEETREKLSGIADYFL
CCCCCCCCEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
IHNRPIFNRVDDSVVRVIKEVPQVLRRARGYAPAPINLPPGFANISPILAMGSQLKNTFC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEE
LLRDGQAILSQHIGDLKNSLAVTAYQKTLNLFLELLEAKPSNIVVDKHPEYLSTKLGKDL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
ANTNNSKIIEVQHHHSHIAACMVENGLDIDCQPVLGIALDGLGYGEDGTIWGGEFLLANY
HCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHEEECCCCCCCCCCEECCEEEEECC
HGFERLGTFKPVAMIGGEQAIYQPWRNTYAHLVAAFGVDFIKNYECLELFSFLQTKPLAL
CCHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
LNQMIEKKINSPLASSCGRLFDAVAAAIGICQESCSYEGQAAISLETLATEYLLNDSEEI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCHHHH
ESYQLDLLQMENVSKFPLTYIVPQPMWQSLLIDTKQSATPALMAAKFHQGLAKAISKMVA
HHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELHQSCEFNQVALTGGVFQNQLLLSLVSDRLIKMGLDVLTHRQVPANDGGLSLGQVAIAA
HHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
ARLRM
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8497190; 9492269 [H]