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The map label for this gene is tkt [H]

Identifier: 113474321

GI number: 113474321

Start: 711457

End: 713475

Strand: Reverse

Name: tkt [H]

Synonym: Tery_0450

Alternate gene names: 113474321

Gene position: 713475-711457 (Counterclockwise)

Preceding gene: 113474322

Following gene: 113474320

Centisome position: 9.21

GC content: 42.15

Gene sequence:

>2019_bases
ATGGCTGTTGCAACTCAATCACTTGAAGAACTTTGCATTAACTCTATTCGCTTTTTAGCAATTGATGCAGTCCAAAAAGC
TAATTCTGGCCATCCAGGACTACCAATGGGTGCGGCACCAATGGCCTTTGTCCTTTGGGATAAGTTGATGCGGTTTAACC
CCAAAAATCCTAAATGGTTAAATCGCGATCGCTTTGTTCTCTCTGCTGGCCACGGCTGTATGTTACAGTATGCTTTGATG
CACTTGACTGGTTATGACAGTGTACCTATAGAGGAAATTAAACAATTCCGTCAGTGGAATTCTAAAACTCCTGGCCATCC
AGAAAATCATATTACTGAAGGTATTGAAGTTACTACTGGGCCACTAGGACAAGGTATTGCTAATGCTGTAGGATTAGCTG
CAGCTGAAGCTCATTTAGCTGCTGTATTTAATAAGCCAGATTGTAATCTCATTGACCATTATACTTATGTAATTGTGGGT
GATGGTTGTAATATGGAGGGGATTTCTGGTGAAGCTTGCTCCCTTGCCGGACACTGGGGTTTAGGTAAGTTAATTGCTTT
CTATGATGATAACCATATCTCTATTGATGGTCACACTGATATTTCTTTTACTGAAGATGTAGGTAAACGTTTTGAAGCTT
ATGGTTGGCACGTTCAGCACGTTAGCGATGGTAATACTAATTTAGAAGCGATCGCTGAAGCTATTGAAAAAGCAAAAGCA
GTTACTGACAAACCTTCCCTAATTAAAGTTACTACTATTATTGGTTACGGTTCTCCTAATAAAGCTGATACTCACGATGT
ACATGGTGCGGCACTAGGTCCTGATGAGGTGGCAGCAACTCGGAAACATCTTGGTTGGGAATATCCAGAGTTTGAGGTTC
CACCAGATGCTCTCAGTCACTTCCGCAAAGCAGTTGAGCGAGGAGCTAAATATGAGGAAGAATGGAATCAATTATTCTCT
GAGTATAAGTCTAAGTATCCTGAAGATGCAGCTACTTTAGAACGGATGGTAAGTGGTAAACTACCTGAAGGTTGGGCGGA
TGCACTACCTAAATATACTCCTGAAAGTAAGAAAGATGCTACTCGTAACCAGTCTGGTGCAACACTCAACGCAATAGCTG
GAGTTTTACCAGAATTAATTGGTGGTTCTGCTGACTTGGCTCCTTCTAACAAAACTTTACTCAAGGGTTTAGGAGATTTT
CAAAAAGGTCAATACCAAAACCGAAATGTGCGCTTTGGGGTTCGGGAACATGGAATGGGAGCAATTTGTAACGGTATTGC
TCTACACGGTTCTGGGTTAATTTCTTATGGTGCAACTTTCTTGGTGTTTACTGACTATATGCGGAACTCTATCCGTTTAT
CTGCTTTAGCTGAAGCTGGTGTTATTTGGGTAATGACTCACGACTCCATCGCTTTGGGTGAAGACGGACCGACTCACCAA
CCAGTTGAACATATTGCATCCTTACGTTTGATTCCACAACTGATAGTTATTCGTCCAGCAGATGGTAATGAAACTTCTGG
GGCTTATAAGATTGCAGTAGAAAAAGCTAAAGCAAGTCATCCTCAACCGACTCTGTTAGCATTATCTCGTCAAGGTTTAC
CTAATTTAGCTGGTAGTTCTATTGATGCGGTTGCTAAAGGTGCTTATGTGCTTAGTGACAGCGAGGGTACTCCTGACATT
ATTCTTATTGGTACTGGTGGTGAAACTTACCAATGTGTGGAAGCTGGTGAAAAACTTCGTGCTGAAGGTAAGAAGGTTCG
GGTAGTTTCTATGCCATGTTGGGAATTATTTGAAGAGCAGGATGCAGCTTATAAGGAGTCTGTGTTCCCTGCGTCTGTGA
AGAAGCGTTTGGCAGTGGAAGCAGGTGTTAGTTTTGGTTGGCATCGTTATGTGACTGATGAAGGTGCGACTTTGAGTGTT
GATACTTTTGGTGCTTCTGCTCCTGGCGGTGTGGTACTGGAAAAGTTTGGATTTACTGTTGATAACATTGTAGCTAAGGC
TAAGGCATTGTTGGGTTAA

Upstream 100 bases:

>100_bases
GGCTTGAGAAACATTCCAGACAAATATCACTGTAGAAAAATATCTGGTTGATCAGCTCTGGCATTTACACACTTGATTAA
TTATATAGATAACGATAACT

Downstream 100 bases:

>100_bases
TTTTGATGGTGGGTTGTTTATAGCGATCGGCTATCAGTTAGGGTTTAAATTTTTAAGCTATTATCTGTAAAGTTTTATGC
CTTAATTGTAGTGCTTGCTA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MAVATQSLEELCINSIRFLAIDAVQKANSGHPGLPMGAAPMAFVLWDKLMRFNPKNPKWLNRDRFVLSAGHGCMLQYALM
HLTGYDSVPIEEIKQFRQWNSKTPGHPENHITEGIEVTTGPLGQGIANAVGLAAAEAHLAAVFNKPDCNLIDHYTYVIVG
DGCNMEGISGEACSLAGHWGLGKLIAFYDDNHISIDGHTDISFTEDVGKRFEAYGWHVQHVSDGNTNLEAIAEAIEKAKA
VTDKPSLIKVTTIIGYGSPNKADTHDVHGAALGPDEVAATRKHLGWEYPEFEVPPDALSHFRKAVERGAKYEEEWNQLFS
EYKSKYPEDAATLERMVSGKLPEGWADALPKYTPESKKDATRNQSGATLNAIAGVLPELIGGSADLAPSNKTLLKGLGDF
QKGQYQNRNVRFGVREHGMGAICNGIALHGSGLISYGATFLVFTDYMRNSIRLSALAEAGVIWVMTHDSIALGEDGPTHQ
PVEHIASLRLIPQLIVIRPADGNETSGAYKIAVEKAKASHPQPTLLALSRQGLPNLAGSSIDAVAKGAYVLSDSEGTPDI
ILIGTGGETYQCVEAGEKLRAEGKKVRVVSMPCWELFEEQDAAYKESVFPASVKKRLAVEAGVSFGWHRYVTDEGATLSV
DTFGASAPGGVVLEKFGFTVDNIVAKAKALLG

Sequences:

>Translated_672_residues
MAVATQSLEELCINSIRFLAIDAVQKANSGHPGLPMGAAPMAFVLWDKLMRFNPKNPKWLNRDRFVLSAGHGCMLQYALM
HLTGYDSVPIEEIKQFRQWNSKTPGHPENHITEGIEVTTGPLGQGIANAVGLAAAEAHLAAVFNKPDCNLIDHYTYVIVG
DGCNMEGISGEACSLAGHWGLGKLIAFYDDNHISIDGHTDISFTEDVGKRFEAYGWHVQHVSDGNTNLEAIAEAIEKAKA
VTDKPSLIKVTTIIGYGSPNKADTHDVHGAALGPDEVAATRKHLGWEYPEFEVPPDALSHFRKAVERGAKYEEEWNQLFS
EYKSKYPEDAATLERMVSGKLPEGWADALPKYTPESKKDATRNQSGATLNAIAGVLPELIGGSADLAPSNKTLLKGLGDF
QKGQYQNRNVRFGVREHGMGAICNGIALHGSGLISYGATFLVFTDYMRNSIRLSALAEAGVIWVMTHDSIALGEDGPTHQ
PVEHIASLRLIPQLIVIRPADGNETSGAYKIAVEKAKASHPQPTLLALSRQGLPNLAGSSIDAVAKGAYVLSDSEGTPDI
ILIGTGGETYQCVEAGEKLRAEGKKVRVVSMPCWELFEEQDAAYKESVFPASVKKRLAVEAGVSFGWHRYVTDEGATLSV
DTFGASAPGGVVLEKFGFTVDNIVAKAKALLG
>Mature_671_residues
AVATQSLEELCINSIRFLAIDAVQKANSGHPGLPMGAAPMAFVLWDKLMRFNPKNPKWLNRDRFVLSAGHGCMLQYALMH
LTGYDSVPIEEIKQFRQWNSKTPGHPENHITEGIEVTTGPLGQGIANAVGLAAAEAHLAAVFNKPDCNLIDHYTYVIVGD
GCNMEGISGEACSLAGHWGLGKLIAFYDDNHISIDGHTDISFTEDVGKRFEAYGWHVQHVSDGNTNLEAIAEAIEKAKAV
TDKPSLIKVTTIIGYGSPNKADTHDVHGAALGPDEVAATRKHLGWEYPEFEVPPDALSHFRKAVERGAKYEEEWNQLFSE
YKSKYPEDAATLERMVSGKLPEGWADALPKYTPESKKDATRNQSGATLNAIAGVLPELIGGSADLAPSNKTLLKGLGDFQ
KGQYQNRNVRFGVREHGMGAICNGIALHGSGLISYGATFLVFTDYMRNSIRLSALAEAGVIWVMTHDSIALGEDGPTHQP
VEHIASLRLIPQLIVIRPADGNETSGAYKIAVEKAKASHPQPTLLALSRQGLPNLAGSSIDAVAKGAYVLSDSEGTPDII
LIGTGGETYQCVEAGEKLRAEGKKVRVVSMPCWELFEEQDAAYKESVFPASVKKRLAVEAGVSFGWHRYVTDEGATLSVD
TFGASAPGGVVLEKFGFTVDNIVAKAKALLG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=590, Percent_Identity=25.2542372881356, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI4507521, Length=590, Percent_Identity=25.2542372881356, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI133778974, Length=582, Percent_Identity=23.7113402061856, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI225637459, Length=592, Percent_Identity=22.1283783783784, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI225637461, Length=514, Percent_Identity=22.568093385214, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI225637463, Length=514, Percent_Identity=22.568093385214, Blast_Score=100, Evalue=8e-21,
Organism=Escherichia coli, GI48994911, Length=674, Percent_Identity=53.2640949554896, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=665, Percent_Identity=53.8345864661654, Blast_Score=683, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=596, Percent_Identity=26.1744966442953, Blast_Score=142, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6325331, Length=669, Percent_Identity=51.7189835575486, Blast_Score=656, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319593, Length=672, Percent_Identity=49.1071428571429, Blast_Score=633, Evalue=0.0,
Organism=Drosophila melanogaster, GI24666278, Length=599, Percent_Identity=25.7095158597663, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI45551847, Length=284, Percent_Identity=34.1549295774648, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI45550715, Length=284, Percent_Identity=34.1549295774648, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24645119, Length=242, Percent_Identity=34.7107438016529, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72428; Mature: 72296

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVATQSLEELCINSIRFLAIDAVQKANSGHPGLPMGAAPMAFVLWDKLMRFNPKNPKWL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
NRDRFVLSAGHGCMLQYALMHLTGYDSVPIEEIKQFRQWNSKTPGHPENHITEGIEVTTG
CCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCEEECC
PLGQGIANAVGLAAAEAHLAAVFNKPDCNLIDHYTYVIVGDGCNMEGISGEACSLAGHWG
CCCHHHHHHHHHHHHHHHHHHEECCCCCCEEECEEEEEEECCCCCCCCCCCCEEECCCCC
LGKLIAFYDDNHISIDGHTDISFTEDVGKRFEAYGWHVQHVSDGNTNLEAIAEAIEKAKA
CCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHH
VTDKPSLIKVTTIIGYGSPNKADTHDVHGAALGPDEVAATRKHLGWEYPEFEVPPDALSH
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
FRKAVERGAKYEEEWNQLFSEYKSKYPEDAATLERMVSGKLPEGWADALPKYTPESKKDA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHH
TRNQSGATLNAIAGVLPELIGGSADLAPSNKTLLKGLGDFQKGQYQNRNVRFGVREHGMG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHCCCCCCCCEEECHHHCCCC
AICNGIALHGSGLISYGATFLVFTDYMRNSIRLSALAEAGVIWVMTHDSIALGEDGPTHQ
HHHCCEEEECCCHHHHCHHHHHHHHHHHCCEEHEEHHCCCEEEEEECCCEEECCCCCCCH
PVEHIASLRLIPQLIVIRPADGNETSGAYKIAVEKAKASHPQPTLLALSRQGLPNLAGSS
HHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCCCCCC
IDAVAKGAYVLSDSEGTPDIILIGTGGETYQCVEAGEKLRAEGKKVRVVSMPCWELFEEQ
HHHHHCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
DAAYKESVFPASVKKRLAVEAGVSFGWHRYVTDEGATLSVDTFGASAPGGVVLEKFGFTV
HHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCH
DNIVAKAKALLG
HHHHHHHHHHCC
>Mature Secondary Structure 
AVATQSLEELCINSIRFLAIDAVQKANSGHPGLPMGAAPMAFVLWDKLMRFNPKNPKWL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
NRDRFVLSAGHGCMLQYALMHLTGYDSVPIEEIKQFRQWNSKTPGHPENHITEGIEVTTG
CCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCEEECC
PLGQGIANAVGLAAAEAHLAAVFNKPDCNLIDHYTYVIVGDGCNMEGISGEACSLAGHWG
CCCHHHHHHHHHHHHHHHHHHEECCCCCCEEECEEEEEEECCCCCCCCCCCCEEECCCCC
LGKLIAFYDDNHISIDGHTDISFTEDVGKRFEAYGWHVQHVSDGNTNLEAIAEAIEKAKA
CCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHH
VTDKPSLIKVTTIIGYGSPNKADTHDVHGAALGPDEVAATRKHLGWEYPEFEVPPDALSH
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
FRKAVERGAKYEEEWNQLFSEYKSKYPEDAATLERMVSGKLPEGWADALPKYTPESKKDA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHH
TRNQSGATLNAIAGVLPELIGGSADLAPSNKTLLKGLGDFQKGQYQNRNVRFGVREHGMG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHCCCCCCCCEEECHHHCCCC
AICNGIALHGSGLISYGATFLVFTDYMRNSIRLSALAEAGVIWVMTHDSIALGEDGPTHQ
HHHCCEEEECCCHHHHCHHHHHHHHHHHCCEEHEEHHCCCEEEEEECCCEEECCCCCCCH
PVEHIASLRLIPQLIVIRPADGNETSGAYKIAVEKAKASHPQPTLLALSRQGLPNLAGSS
HHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCCCCCC
IDAVAKGAYVLSDSEGTPDIILIGTGGETYQCVEAGEKLRAEGKKVRVVSMPCWELFEEQ
HHHHHCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
DAAYKESVFPASVKKRLAVEAGVSFGWHRYVTDEGATLSVDTFGASAPGGVVLEKFGFTV
HHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCH
DNIVAKAKALLG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]