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The map label for this gene is atpA

Identifier: 110835589

GI number: 110835589

Start: 3085619

End: 3087163

Strand: Reverse

Name: atpA

Synonym: ABO_2728

Alternate gene names: 110835589

Gene position: 3087163-3085619 (Counterclockwise)

Preceding gene: 110835590

Following gene: 110835588

Centisome position: 98.94

GC content: 53.85

Gene sequence:

>1545_bases
ATGCAGCAACTCAACCCGTCCGAAATCAGCGAGATTATCAAGTCGCGCATTGCGAAACTTGATACCTCCACCGAAGCACG
CAACGAAGGTACGGTGGTTTCCGTATCTGATGGTATTGTGCGCATTCATGGTCTGGCCGACGTGATGTTCGGCGAGATGA
TCGAGTTTGAGGGCGGCATCTACGGCATGGCCCTTAACCTGGAGCAAGACTCTGTCGGCGCCGTGGTGCTGGGTGATTAC
CTGGGCCTAGCCGAAGGCCAAAAAGTTCGTTGTACCGGTCGTATTCTGGAAGTCCCCACTGGCCCCGAAATGCTGGGTCG
TGTTGTTGACGCTCTAGGTAATCCGATTGACGGTAAAGGCCCGATCGAAGCCAAGCAAACCGATGCGGTTGAAAAGGTAG
CGCCCGGCGTTATCTGGCGTCGTGAAGTTAACGAGCCTGTTCAAACCGGTTACAAGTCCATCGATGCCATGGTGCCAATC
GGCCGTGGTCAGCGTGAGCTGATCATTGGTGACCGCCAGATCGGTAAGACCGCCGTGGCGGTTGATGCGATTATCAACCA
GAAAGACTCCGGCATTAAGTGTGTCTACGTCGCCATCGGCCAGAAGCAGTCCACCATTGCTAACGTGGTGCGCAAACTGG
AAGAGCACGGCGCGATGGAAAACACCATCATCGTTGCGGCCTCCGCTTCTGATCCGGCTTCCATGCAGTTCCTGGCACCG
TTTGCTGGCTGCACCATGGGCGAGTATTTCCGTGATCGCGGTGAAGATGCACTGATCGTTTATGATGATCTGACCAAGCA
GGCGTGGGCGTATCGCCAGATCTCCCTGCTGCTGCGTCGTCCGCCGGGCCGTGAAGCTTATCCTGGTGACGTGTTCTACC
TGCACTCCCGTCTACTGGAGCGCGCCGCCAAGGTAAACGAAGATTATGTTGAGAAGTTCACCAACGGTGAAGTGAAAGGT
AAGACCGGTTCTTTGACCGCTCTGCCTATCATTGAAACCCAAGGTGGTGACGTTTCTGCTTTCGTACCGACCAACGTGAT
TTCCATTACCGATGGTCAGATCTTCCTGGAAACCGACCTGTTCAACTCCGGCATTCGCCCGGCGATGAACGCCGGTGTGT
CTGTATCCCGTGTAGGTGGTGCAGCCCAGACCAAGATCGTTAAGAAGCTGGGTGGTGGTATTCGTTTGGCTCTGGCTCAG
TACCGTGAACTGGCTGCATTCGCTCAGTTCGCTTCCGACCTCGATGATTCTACTCGTGAGCAGTTGGAGCATGGTCAAGC
CGTTACCGAGCTGATGAAGCAGAAGCAGTACAGCCCGATGAGCGTTGCTGAAATGGGTGTTGTGCTGTACGCCGCTAACG
AAGGTTACCTAAAAGGTATGGAAGTCGAAAAAATCGGCGCCTTTGAAGCTGCACTGCTGGACTACATGAACAGCGAAAAG
AAAGCGTTGATGGATAAAATCAACGAGAAGGGTGACTACAACGGCGAGATCGAAGCTGAGATTAAAGAATCTCTCGATCA
GTTCAAAGCTACCCAGACCTGGTAA

Upstream 100 bases:

>100_bases
GTGCTGGTGCGAGCCGGCGATACCGTAATTGATGGCAGTGTGCGCGGCCGGCTTAATCGCTTGGCAGAGCAACTGAACTC
TTGAGTTTGAGGGATTAGAG

Downstream 100 bases:

>100_bases
TTCGCTGATAAAGGAACGTTCCTATGGCCAGCGGTAAAGAGATCAAAGGCAAAATTGCCAGCGTCCAGAGCACGAAGAAA
ATTACTCGTGCAATGGAAAT

Product: ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQQLNPSEISEIIKSRIAKLDTSTEARNEGTVVSVSDGIVRIHGLADVMFGEMIEFEGGIYGMALNLEQDSVGAVVLGDY
LGLAEGQKVRCTGRILEVPTGPEMLGRVVDALGNPIDGKGPIEAKQTDAVEKVAPGVIWRREVNEPVQTGYKSIDAMVPI
GRGQRELIIGDRQIGKTAVAVDAIINQKDSGIKCVYVAIGQKQSTIANVVRKLEEHGAMENTIIVAASASDPASMQFLAP
FAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKVNEDYVEKFTNGEVKG
KTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLETDLFNSGIRPAMNAGVSVSRVGGAAQTKIVKKLGGGIRLALAQ
YRELAAFAQFASDLDDSTREQLEHGQAVTELMKQKQYSPMSVAEMGVVLYAANEGYLKGMEVEKIGAFEAALLDYMNSEK
KALMDKINEKGDYNGEIEAEIKESLDQFKATQTW

Sequences:

>Translated_514_residues
MQQLNPSEISEIIKSRIAKLDTSTEARNEGTVVSVSDGIVRIHGLADVMFGEMIEFEGGIYGMALNLEQDSVGAVVLGDY
LGLAEGQKVRCTGRILEVPTGPEMLGRVVDALGNPIDGKGPIEAKQTDAVEKVAPGVIWRREVNEPVQTGYKSIDAMVPI
GRGQRELIIGDRQIGKTAVAVDAIINQKDSGIKCVYVAIGQKQSTIANVVRKLEEHGAMENTIIVAASASDPASMQFLAP
FAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKVNEDYVEKFTNGEVKG
KTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLETDLFNSGIRPAMNAGVSVSRVGGAAQTKIVKKLGGGIRLALAQ
YRELAAFAQFASDLDDSTREQLEHGQAVTELMKQKQYSPMSVAEMGVVLYAANEGYLKGMEVEKIGAFEAALLDYMNSEK
KALMDKINEKGDYNGEIEAEIKESLDQFKATQTW
>Mature_514_residues
MQQLNPSEISEIIKSRIAKLDTSTEARNEGTVVSVSDGIVRIHGLADVMFGEMIEFEGGIYGMALNLEQDSVGAVVLGDY
LGLAEGQKVRCTGRILEVPTGPEMLGRVVDALGNPIDGKGPIEAKQTDAVEKVAPGVIWRREVNEPVQTGYKSIDAMVPI
GRGQRELIIGDRQIGKTAVAVDAIINQKDSGIKCVYVAIGQKQSTIANVVRKLEEHGAMENTIIVAASASDPASMQFLAP
FAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKVNEDYVEKFTNGEVKG
KTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLETDLFNSGIRPAMNAGVSVSRVGGAAQTKIVKKLGGGIRLALAQ
YRELAAFAQFASDLDDSTREQLEHGQAVTELMKQKQYSPMSVAEMGVVLYAANEGYLKGMEVEKIGAFEAALLDYMNSEK
KALMDKINEKGDYNGEIEAEIKESLDQFKATQTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=518, Percent_Identity=56.7567567567568, Blast_Score=587, Evalue=1e-168,
Organism=Homo sapiens, GI4757810, Length=518, Percent_Identity=56.7567567567568, Blast_Score=587, Evalue=1e-168,
Organism=Homo sapiens, GI19913428, Length=317, Percent_Identity=28.7066246056782, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI19913426, Length=322, Percent_Identity=27.639751552795, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI32189394, Length=324, Percent_Identity=26.5432098765432, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI19913424, Length=337, Percent_Identity=25.8160237388724, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1790172, Length=512, Percent_Identity=74.0234375, Blast_Score=799, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=357, Percent_Identity=25.7703081232493, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=27.0462633451957, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=513, Percent_Identity=56.3352826510721, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988080, Length=513, Percent_Identity=56.3352826510721, Blast_Score=576, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988074, Length=513, Percent_Identity=53.0214424951267, Blast_Score=532, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI17510931, Length=377, Percent_Identity=27.8514588859416, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=305, Percent_Identity=28.1967213114754, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=305, Percent_Identity=26.5573770491803, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=247, Percent_Identity=26.7206477732794, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988068, Length=79, Percent_Identity=43.0379746835443, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=56, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=514, Percent_Identity=56.420233463035, Blast_Score=590, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6319603, Length=308, Percent_Identity=29.2207792207792, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=328, Percent_Identity=26.8292682926829, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24658560, Length=513, Percent_Identity=55.1656920077973, Blast_Score=563, Evalue=1e-161,
Organism=Drosophila melanogaster, GI281361666, Length=306, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24646341, Length=306, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17136796, Length=306, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24638766, Length=324, Percent_Identity=26.2345679012346, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI28574560, Length=323, Percent_Identity=25.6965944272446, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583992, Length=319, Percent_Identity=25.705329153605, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583988, Length=248, Percent_Identity=27.8225806451613, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583986, Length=248, Percent_Identity=27.8225806451613, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583984, Length=248, Percent_Identity=27.8225806451613, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129479, Length=360, Percent_Identity=26.1111111111111, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_ALCBS (Q0VKX2)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694448.1
- ProteinModelPortal:   Q0VKX2
- SMR:   Q0VKX2
- STRING:   Q0VKX2
- GeneID:   4213842
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2728
- NMPDR:   fig|393595.12.peg.2737
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q0VKX2
- BioCyc:   ABOR393595:ABO_2728-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55828; Mature: 55828

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLNPSEISEIIKSRIAKLDTSTEARNEGTVVSVSDGIVRIHGLADVMFGEMIEFEGGI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCE
YGMALNLEQDSVGAVVLGDYLGLAEGQKVRCTGRILEVPTGPEMLGRVVDALGNPIDGKG
EEEEEECCCCCCCEEEEEHHHCCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCC
PIEAKQTDAVEKVAPGVIWRREVNEPVQTGYKSIDAMVPIGRGQRELIIGDRQIGKTAVA
CCCCHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHEECCCCCCCEEEECCCHHCCHHHH
VDAIINQKDSGIKCVYVAIGQKQSTIANVVRKLEEHGAMENTIIVAASASDPASMQFLAP
HHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHH
FAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
HHCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKVNEDYVEKFTNGEVKGKTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLETDL
HHHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECC
FNSGIRPAMNAGVSVSRVGGAAQTKIVKKLGGGIRLALAQYRELAAFAQFASDLDDSTRE
CCCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QLEHGQAVTELMKQKQYSPMSVAEMGVVLYAANEGYLKGMEVEKIGAFEAALLDYMNSEK
HHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHH
KALMDKINEKGDYNGEIEAEIKESLDQFKATQTW
HHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQLNPSEISEIIKSRIAKLDTSTEARNEGTVVSVSDGIVRIHGLADVMFGEMIEFEGGI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCE
YGMALNLEQDSVGAVVLGDYLGLAEGQKVRCTGRILEVPTGPEMLGRVVDALGNPIDGKG
EEEEEECCCCCCCEEEEEHHHCCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCC
PIEAKQTDAVEKVAPGVIWRREVNEPVQTGYKSIDAMVPIGRGQRELIIGDRQIGKTAVA
CCCCHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHEECCCCCCCEEEECCCHHCCHHHH
VDAIINQKDSGIKCVYVAIGQKQSTIANVVRKLEEHGAMENTIIVAASASDPASMQFLAP
HHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHH
FAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
HHCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKVNEDYVEKFTNGEVKGKTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLETDL
HHHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECC
FNSGIRPAMNAGVSVSRVGGAAQTKIVKKLGGGIRLALAQYRELAAFAQFASDLDDSTRE
CCCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QLEHGQAVTELMKQKQYSPMSVAEMGVVLYAANEGYLKGMEVEKIGAFEAALLDYMNSEK
HHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHH
KALMDKINEKGDYNGEIEAEIKESLDQFKATQTW
HHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA