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The map label for this gene is yegE [H]

Identifier: 110835527

GI number: 110835527

Start: 3013845

End: 3015308

Strand: Reverse

Name: yegE [H]

Synonym: ABO_2666

Alternate gene names: 110835527

Gene position: 3015308-3013845 (Counterclockwise)

Preceding gene: 110835528

Following gene: 110835525

Centisome position: 96.64

GC content: 54.64

Gene sequence:

>1464_bases
ATGCAAGATCGGGGTGATTTCAGCCTTACCGGCCTGAGAGAATTACACCAGCTCTCATTGCTGCCTAGCGGGGACTTTAA
TGCACTTTATGCGGCCTACCTAGAGGTGGGGCGCAGCCTGCTGGAGCTTTCTATTGGCATTGTTAGTTGCATTAAAGACG
GTGACTACGAAGTGCTAGCGGTGCAACCGGGCGATGGTGGTATCAGCCCCGGTGATCATTTCCCTCTGGGTGATACTTAC
TGCTCCACCGTAATGAGCAAGCAAGGCTCGGTAGCGTTGCACCATGTGGGTGAACTGGAAGAGATGCGTTCGCACCCAGT
GTATGTGGGGATGCAGTTAGAATCCTATATAGCTGTGCCGTTGTATGTGCAGGGTGAGATTTTCGGCACCCTTAATTTCA
GTGATCCGTCACCGCGCCGTGAAGCTTTCAGCATCGAGGAAATGGAGTTTTTGGAATTGATGGGGAAGTCTCTCAGCCAG
ACGCTAGAGCAGGACCGGCTGAGTCAACAACAGCAAGCGGCCGTTAGTAAAATGGAAGAGAACATGGCCCTGTTCGAAGG
GGCTTTTCGCCACGCAGCCATCGGCATGGCGATTGTGTCGCCGCAAGGCGGCTGGATGCGGGTGAATCAAGCGCTGTGCA
GCATTCTGGGTTATGACGAAGAGGCGCTGCTGGCCAGTGACTTCCAGACCATAACGCACCCGGATGACCTGGAAACCGAC
TTGCATCATGTGGAAGAGATGCTGACAGGCAAACGTAGCAGTTACTGGATGAAGAAACGCTATATCCATAAGAATGGCCA
TATTGTCTGGGTGTTGTTGGCCGTCTCTCTTGTCCGTAATGGGGATGGTTCGCCCCGTTATTTTTTATCCCAAATCGAAG
ATATCACCGCTCAAGTAACGGCGGAATTGACCCTGCGCGAAAAACAGGGCGAGCTGGAGGAGCTCAACCAAGAGCTGGCG
AGCATGGCTCGTACTGACCCGCTCACCGGGCTCTATAACCGATTGGTGTTGATGGAAGGTTTGCGCCAAGAGTTCAGTCG
CTGTGAGCGTCGTAGCGAGCCTATGTCGGTAATTTTCATGGATGTGGATCATTTCAAGCAGTACAACGATAGCTACGGGC
ACGTAGAAGGGGATGCGGCCCTGCAGGCAGTGGCCGAGGCTCTGCGTCCGGTTATTCGTGATACCGATGTGTTGGCGCGT
TACGGTGGCGAAGAGTTTGTTGCCTTGCTGCCCACCGCTAATTCGCAAGATGCTGAAAGGGTGGCAGAACGTTGTCGCCG
TGCCGTGGCGGAGATTTCTTCGCTCAGCAGGCCGGTGAGCCTGAGTGTGGGTGTGGCCACGCTCAGGTTCGGTGATGAAG
CTGATGAAACGAAGAGCCCCGAATCGCTACTAAGCGCGGCGGATCGAGCGCTTTATGTAGCGAAGGGGGCCGGCCGCAAC
CGCGTTCATACCGCGCAGCTCTAA

Upstream 100 bases:

>100_bases
CAAATAAGTGCAAGGGTTTTTACTTGTTCTGAACCTTTGGTTACAACGTAAGAGTAAAAACGGTGTCGTGATAGGACGGG
CGCCAAGCACGGGGAAAAAT

Downstream 100 bases:

>100_bases
TGTTTGAAGCCCGTCTTTTATTGTCGGTGGCGGTGCGGACATCGCAACGTCATGGTGCTTCTCTTGCGGAAGAGGTGAAT
GGGTTTCTATGAATGACGCT

Product: GAF/PAS/GGDEF domain-containing protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MQDRGDFSLTGLRELHQLSLLPSGDFNALYAAYLEVGRSLLELSIGIVSCIKDGDYEVLAVQPGDGGISPGDHFPLGDTY
CSTVMSKQGSVALHHVGELEEMRSHPVYVGMQLESYIAVPLYVQGEIFGTLNFSDPSPRREAFSIEEMEFLELMGKSLSQ
TLEQDRLSQQQQAAVSKMEENMALFEGAFRHAAIGMAIVSPQGGWMRVNQALCSILGYDEEALLASDFQTITHPDDLETD
LHHVEEMLTGKRSSYWMKKRYIHKNGHIVWVLLAVSLVRNGDGSPRYFLSQIEDITAQVTAELTLREKQGELEELNQELA
SMARTDPLTGLYNRLVLMEGLRQEFSRCERRSEPMSVIFMDVDHFKQYNDSYGHVEGDAALQAVAEALRPVIRDTDVLAR
YGGEEFVALLPTANSQDAERVAERCRRAVAEISSLSRPVSLSVGVATLRFGDEADETKSPESLLSAADRALYVAKGAGRN
RVHTAQL

Sequences:

>Translated_487_residues
MQDRGDFSLTGLRELHQLSLLPSGDFNALYAAYLEVGRSLLELSIGIVSCIKDGDYEVLAVQPGDGGISPGDHFPLGDTY
CSTVMSKQGSVALHHVGELEEMRSHPVYVGMQLESYIAVPLYVQGEIFGTLNFSDPSPRREAFSIEEMEFLELMGKSLSQ
TLEQDRLSQQQQAAVSKMEENMALFEGAFRHAAIGMAIVSPQGGWMRVNQALCSILGYDEEALLASDFQTITHPDDLETD
LHHVEEMLTGKRSSYWMKKRYIHKNGHIVWVLLAVSLVRNGDGSPRYFLSQIEDITAQVTAELTLREKQGELEELNQELA
SMARTDPLTGLYNRLVLMEGLRQEFSRCERRSEPMSVIFMDVDHFKQYNDSYGHVEGDAALQAVAEALRPVIRDTDVLAR
YGGEEFVALLPTANSQDAERVAERCRRAVAEISSLSRPVSLSVGVATLRFGDEADETKSPESLLSAADRALYVAKGAGRN
RVHTAQL
>Mature_487_residues
MQDRGDFSLTGLRELHQLSLLPSGDFNALYAAYLEVGRSLLELSIGIVSCIKDGDYEVLAVQPGDGGISPGDHFPLGDTY
CSTVMSKQGSVALHHVGELEEMRSHPVYVGMQLESYIAVPLYVQGEIFGTLNFSDPSPRREAFSIEEMEFLELMGKSLSQ
TLEQDRLSQQQQAAVSKMEENMALFEGAFRHAAIGMAIVSPQGGWMRVNQALCSILGYDEEALLASDFQTITHPDDLETD
LHHVEEMLTGKRSSYWMKKRYIHKNGHIVWVLLAVSLVRNGDGSPRYFLSQIEDITAQVTAELTLREKQGELEELNQELA
SMARTDPLTGLYNRLVLMEGLRQEFSRCERRSEPMSVIFMDVDHFKQYNDSYGHVEGDAALQAVAEALRPVIRDTDVLAR
YGGEEFVALLPTANSQDAERVAERCRRAVAEISSLSRPVSLSVGVATLRFGDEADETKSPESLLSAADRALYVAKGAGRN
RVHTAQL

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=127, Percent_Identity=48.8188976377953, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI145693134, Length=198, Percent_Identity=35.8585858585859, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082007, Length=239, Percent_Identity=35.9832635983264, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=34.2696629213483, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=33.9285714285714, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081881, Length=183, Percent_Identity=37.1584699453552, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787802, Length=247, Percent_Identity=28.7449392712551, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=34.1317365269461, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081974, Length=167, Percent_Identity=30.5389221556886, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788085, Length=173, Percent_Identity=30.635838150289, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787541, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788956, Length=175, Percent_Identity=32.5714285714286, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 54043; Mature: 54043

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRGDFSLTGLRELHQLSLLPSGDFNALYAAYLEVGRSLLELSIGIVSCIKDGDYEVLA
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VQPGDGGISPGDHFPLGDTYCSTVMSKQGSVALHHVGELEEMRSHPVYVGMQLESYIAVP
EECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHCCCEEEEEEECCEEEEE
LYVQGEIFGTLNFSDPSPRREAFSIEEMEFLELMGKSLSQTLEQDRLSQQQQAAVSKMEE
EEEECEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMALFEGAFRHAAIGMAIVSPQGGWMRVNQALCSILGYDEEALLASDFQTITHPDDLETD
HHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCCHHH
LHHVEEMLTGKRSSYWMKKRYIHKNGHIVWVLLAVSLVRNGDGSPRYFLSQIEDITAQVT
HHHHHHHHCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AELTLREKQGELEELNQELASMARTDPLTGLYNRLVLMEGLRQEFSRCERRSEPMSVIFM
HHHEEHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
DVDHFKQYNDSYGHVEGDAALQAVAEALRPVIRDTDVLARYGGEEFVALLPTANSQDAER
EHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEECCCCCCHHHH
VAERCRRAVAEISSLSRPVSLSVGVATLRFGDEADETKSPESLLSAADRALYVAKGAGRN
HHHHHHHHHHHHHHCCCCCEEEECEEEEECCCCCCCCCCHHHHHHHHHHEEEEECCCCCC
RVHTAQL
CCEECCC
>Mature Secondary Structure
MQDRGDFSLTGLRELHQLSLLPSGDFNALYAAYLEVGRSLLELSIGIVSCIKDGDYEVLA
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VQPGDGGISPGDHFPLGDTYCSTVMSKQGSVALHHVGELEEMRSHPVYVGMQLESYIAVP
EECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHCCCEEEEEEECCEEEEE
LYVQGEIFGTLNFSDPSPRREAFSIEEMEFLELMGKSLSQTLEQDRLSQQQQAAVSKMEE
EEEECEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMALFEGAFRHAAIGMAIVSPQGGWMRVNQALCSILGYDEEALLASDFQTITHPDDLETD
HHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCCHHH
LHHVEEMLTGKRSSYWMKKRYIHKNGHIVWVLLAVSLVRNGDGSPRYFLSQIEDITAQVT
HHHHHHHHCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AELTLREKQGELEELNQELASMARTDPLTGLYNRLVLMEGLRQEFSRCERRSEPMSVIFM
HHHEEHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
DVDHFKQYNDSYGHVEGDAALQAVAEALRPVIRDTDVLARYGGEEFVALLPTANSQDAER
EHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEECCCCCCHHHH
VAERCRRAVAEISSLSRPVSLSVGVATLRFGDEADETKSPESLLSAADRALYVAKGAGRN
HHHHHHHHHHHHHHCCCCCEEEECEEEEECCCCCCCCCCHHHHHHHHHHEEEEECCCCCC
RVHTAQL
CCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]