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The map label for this gene is orn

Identifier: 110835071

GI number: 110835071

Start: 2523189

End: 2523734

Strand: Reverse

Name: orn

Synonym: ABO_2210

Alternate gene names: 110835071

Gene position: 2523734-2523189 (Counterclockwise)

Preceding gene: 110835077

Following gene: 110835069

Centisome position: 80.89

GC content: 53.11

Gene sequence:

>546_bases
ATGACCGACAAGCGCAATAATCTGATTTGGATCGATCTGGAAATGACCGGCCTGAGCCCGGAAAATGATCGCATCATCGA
AATCGCCACTATTGTTACTGATGCCGAGCTAAACGTGTTGGCAGAAGGGCCGGTGTTGGCGGTTCATCAAAGCGATGCGC
TACTGGATGGCATGGACGAGTGGAATACCACCCACCATAACAACTCCGGGCTGGTGGCCAGAGTGAAGGCCAGCACGGTG
AATGATGCGGCCGCGGAGTCTCAGACTATTGCGTTTCTGGAGCAGTATGTGGAAGCGGGTATGTCGCCCATGTGCGGCAA
TAGTATCTGTCAGGATCGCCGTTTTCTGGCCAACTATATGCCGAAACTGGAAGCCTTCTTCCATTATCGCAACTTGGATG
TGTCCACCCTGAAAGAATTGGCGCGTCGCTGGAAGCCGGACATCCTGCCGGGCTTCAGTAAAGAGAACAAACACCTGGCG
CTGGATGATATTCGCGAGTCCATCGCCGAACTGGTGTATTACCGCGAGCACTTTATTGACGCTTGA

Upstream 100 bases:

>100_bases
GGTCCTGTGTTCGGGTGTGAGATCTGTTATGTGAATAGCGCCATGCTACCATGAAGCATCAACAGACCTTCACCCTGCGT
AGCAAAGAGATGCCGAGCCC

Downstream 100 bases:

>100_bases
TCGGCGTCGCTGCATCGCGACCACAGAGTGAACCCATTGCTTTCCTTTGTGATCTCTGTGGTAAATCCTAGCTTGCTTGG
TGCTGCTCCAGCGCCCACCG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTDKRNNLIWIDLEMTGLSPENDRIIEIATIVTDAELNVLAEGPVLAVHQSDALLDGMDEWNTTHHNNSGLVARVKASTV
NDAAAESQTIAFLEQYVEAGMSPMCGNSICQDRRFLANYMPKLEAFFHYRNLDVSTLKELARRWKPDILPGFSKENKHLA
LDDIRESIAELVYYREHFIDA

Sequences:

>Translated_181_residues
MTDKRNNLIWIDLEMTGLSPENDRIIEIATIVTDAELNVLAEGPVLAVHQSDALLDGMDEWNTTHHNNSGLVARVKASTV
NDAAAESQTIAFLEQYVEAGMSPMCGNSICQDRRFLANYMPKLEAFFHYRNLDVSTLKELARRWKPDILPGFSKENKHLA
LDDIRESIAELVYYREHFIDA
>Mature_180_residues
TDKRNNLIWIDLEMTGLSPENDRIIEIATIVTDAELNVLAEGPVLAVHQSDALLDGMDEWNTTHHNNSGLVARVKASTVN
DAAAESQTIAFLEQYVEAGMSPMCGNSICQDRRFLANYMPKLEAFFHYRNLDVSTLKELARRWKPDILPGFSKENKHLAL
DDIRESIAELVYYREHFIDA

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=173, Percent_Identity=48.5549132947977, Blast_Score=176, Evalue=1e-44,
Organism=Escherichia coli, GI87082382, Length=179, Percent_Identity=71.5083798882682, Blast_Score=269, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI17557752, Length=173, Percent_Identity=50.8670520231214, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323088, Length=186, Percent_Identity=37.6344086021505, Blast_Score=120, Evalue=9e-29,
Organism=Drosophila melanogaster, GI21355135, Length=170, Percent_Identity=47.6470588235294, Blast_Score=175, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_ALCBS (Q0VME0)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693930.1
- ProteinModelPortal:   Q0VME0
- SMR:   Q0VME0
- STRING:   Q0VME0
- GeneID:   4211633
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2210
- NMPDR:   fig|393595.12.peg.2209
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   Q0VME0
- ProtClustDB:   PRK05359
- BioCyc:   ABOR393595:ABO_2210-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20522; Mature: 20391

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRNNLIWIDLEMTGLSPENDRIIEIATIVTDAELNVLAEGPVLAVHQSDALLDGMDE
CCCCCCCEEEEEEEEECCCCCCCCEEEEEEEEECCCCEEEECCCEEEEECCCCHHCCHHH
WNTTHHNNSGLVARVKASTVNDAAAESQTIAFLEQYVEAGMSPMCGNSICQDRRFLANYM
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
PKLEAFFHYRNLDVSTLKELARRWKPDILPGFSKENKHLALDDIRESIAELVYYREHFID
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure 
TDKRNNLIWIDLEMTGLSPENDRIIEIATIVTDAELNVLAEGPVLAVHQSDALLDGMDE
CCCCCCEEEEEEEEECCCCCCCCEEEEEEEEECCCCEEEECCCEEEEECCCCHHCCHHH
WNTTHHNNSGLVARVKASTVNDAAAESQTIAFLEQYVEAGMSPMCGNSICQDRRFLANYM
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
PKLEAFFHYRNLDVSTLKELARRWKPDILPGFSKENKHLALDDIRESIAELVYYREHFID
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA