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The map label for this gene is dhbP [H]

Identifier: 110835033

GI number: 110835033

Start: 2481040

End: 2482149

Strand: Reverse

Name: dhbP [H]

Synonym: ABO_2172

Alternate gene names: 110835033

Gene position: 2482149-2481040 (Counterclockwise)

Preceding gene: 110835034

Following gene: 110835032

Centisome position: 79.55

GC content: 55.41

Gene sequence:

>1110_bases
ATGCAGCTCAATAGTATTGAAGAACTGATCGAAGATATCCGTCAGGGAAAGATGGTTATTCTGATGGACGATGAGGATCG
CGAGAACGAAGGTGACCTGGTGATGGCTGCGGAACATGTGACTGCGGAAGCCATTAACTTTATGGCCAAGTATGGTCGTG
GCCTGATCTGTATGCCCATGTCCCGCGAGCGGTGTGAGTTGCTGGATTTGCCCTTGATGGTGCAGAGCAATGGCAGCGGT
TTTGGCACTAAATTCACCGTCTCCATCGAGGCCCGCGAAGGTGTCACCACCGGTATTTCTGCGGCCGACCGTGCCCGTAC
CGTGCAAGCCGCCGTCGCCCGTAATGCCCGCGCCGATGACATTGTGCAGCCGGGCCACATTTTTCCGCTGATGGCGGAGC
CGGGTGGCGTACTACGCCGGGCCGGGCATACCGAGGCCTCCTGCGATCTGGCTGCACTGGCTGGCTGCGAGCCGTCCGGG
GTGATTTGTGAAGTCATGAATGAAGATGGCTCCATGGCCCGCCGCGAAGACTTGGAAGTGTTTGCCGCGGAGCACGATCT
GAAAATCGGGACTATTGCGGACCTGATTCAATATCGTGCCCTGAACGAACAGACCATCGAGCAGGTGTCCGATCACGAGC
TAGAGACCTGGTACGGGAATTTCCGTTTGGTGGCGTTCCGCGACACCGTGGATGGGTTGACCCATGTGGCGCTGGTGAAG
GGCGATATTCACGAGGATGAAGAAGTGGCAGTGCGGGTGCACCAAGTGGATCCGTTGCGTGATTTAATGAGCGCGAAAAT
GAATGGCCGTACCGGCTGGAACATGCACCGAGTGCTTGAAACTGTTTCCCAGTCTGATGCCGGTGTGGTGATTATTCTGG
GTCAGGATTATGCCTCCAACGATATTGTGGAGCGCCTAGATGTCTTTTTCGGTGGTGCTGCAGGCAAGCCAAAGGGCGAA
TCCCGTGCTTACCGTAATATTGGCACCGGCTCCCAGATTCTGAAGGCGCTGGGAGTGCGCAAAATGCGCTTGCTCAGTTC
TCCTATGAAATTCAATGCGTTGAGCGGTTTCGATTTGGAAATCACTGAGTATGTCGACGCGGATAGTTAA

Upstream 100 bases:

>100_bases
CGATTTGGGCTAAGCGCGGGCACGGCACAGGTGAAGTACTGTGCCAATCCGCGTTCCCACGTTTAATTTTTAACTTTCAA
CTCCAACAGCGAGTGAAGTT

Downstream 100 bases:

>100_bases
GCGAAACGCTTGATGCTTGACGCCCGACGCCTGACGCTGTCCCATTTAAGCGTTGAGTATTGGGCTTCCTGCGTCAGGCA
GCTAATCGAAACCACTGGAA

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MQLNSIEELIEDIRQGKMVILMDDEDRENEGDLVMAAEHVTAEAINFMAKYGRGLICMPMSRERCELLDLPLMVQSNGSG
FGTKFTVSIEAREGVTTGISAADRARTVQAAVARNARADDIVQPGHIFPLMAEPGGVLRRAGHTEASCDLAALAGCEPSG
VICEVMNEDGSMARREDLEVFAAEHDLKIGTIADLIQYRALNEQTIEQVSDHELETWYGNFRLVAFRDTVDGLTHVALVK
GDIHEDEEVAVRVHQVDPLRDLMSAKMNGRTGWNMHRVLETVSQSDAGVVIILGQDYASNDIVERLDVFFGGAAGKPKGE
SRAYRNIGTGSQILKALGVRKMRLLSSPMKFNALSGFDLEITEYVDADS

Sequences:

>Translated_369_residues
MQLNSIEELIEDIRQGKMVILMDDEDRENEGDLVMAAEHVTAEAINFMAKYGRGLICMPMSRERCELLDLPLMVQSNGSG
FGTKFTVSIEAREGVTTGISAADRARTVQAAVARNARADDIVQPGHIFPLMAEPGGVLRRAGHTEASCDLAALAGCEPSG
VICEVMNEDGSMARREDLEVFAAEHDLKIGTIADLIQYRALNEQTIEQVSDHELETWYGNFRLVAFRDTVDGLTHVALVK
GDIHEDEEVAVRVHQVDPLRDLMSAKMNGRTGWNMHRVLETVSQSDAGVVIILGQDYASNDIVERLDVFFGGAAGKPKGE
SRAYRNIGTGSQILKALGVRKMRLLSSPMKFNALSGFDLEITEYVDADS
>Mature_369_residues
MQLNSIEELIEDIRQGKMVILMDDEDRENEGDLVMAAEHVTAEAINFMAKYGRGLICMPMSRERCELLDLPLMVQSNGSG
FGTKFTVSIEAREGVTTGISAADRARTVQAAVARNARADDIVQPGHIFPLMAEPGGVLRRAGHTEASCDLAALAGCEPSG
VICEVMNEDGSMARREDLEVFAAEHDLKIGTIADLIQYRALNEQTIEQVSDHELETWYGNFRLVAFRDTVDGLTHVALVK
GDIHEDEEVAVRVHQVDPLRDLMSAKMNGRTGWNMHRVLETVSQSDAGVVIILGQDYASNDIVERLDVFFGGAAGKPKGE
SRAYRNIGTGSQILKALGVRKMRLLSSPMKFNALSGFDLEITEYVDADS

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=199, Percent_Identity=49.748743718593, Blast_Score=215, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=41.6666666666667, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40457; Mature: 40457

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSIEELIEDIRQGKMVILMDDEDRENEGDLVMAAEHVTAEAINFMAKYGRGLICMPM
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEECC
SRERCELLDLPLMVQSNGSGFGTKFTVSIEAREGVTTGISAADRARTVQAAVARNARADD
CCCCHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
IVQPGHIFPLMAEPGGVLRRAGHTEASCDLAALAGCEPSGVICEVMNEDGSMARREDLEV
CCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHE
FAAEHDLKIGTIADLIQYRALNEQTIEQVSDHELETWYGNFRLVAFRDTVDGLTHVALVK
EEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCEEEEEEECCCCCHHEEEEEE
GDIHEDEEVAVRVHQVDPLRDLMSAKMNGRTGWNMHRVLETVSQSDAGVVIILGQDYASN
CCCCCCHHHEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCH
DIVERLDVFFGGAAGKPKGESRAYRNIGTGSQILKALGVRKMRLLSSPMKFNALSGFDLE
HHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEE
ITEYVDADS
EECCCCCCC
>Mature Secondary Structure
MQLNSIEELIEDIRQGKMVILMDDEDRENEGDLVMAAEHVTAEAINFMAKYGRGLICMPM
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEECC
SRERCELLDLPLMVQSNGSGFGTKFTVSIEAREGVTTGISAADRARTVQAAVARNARADD
CCCCHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
IVQPGHIFPLMAEPGGVLRRAGHTEASCDLAALAGCEPSGVICEVMNEDGSMARREDLEV
CCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHE
FAAEHDLKIGTIADLIQYRALNEQTIEQVSDHELETWYGNFRLVAFRDTVDGLTHVALVK
EEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCEEEEEEECCCCCHHEEEEEE
GDIHEDEEVAVRVHQVDPLRDLMSAKMNGRTGWNMHRVLETVSQSDAGVVIILGQDYASN
CCCCCCHHHEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCH
DIVERLDVFFGGAAGKPKGESRAYRNIGTGSQILKALGVRKMRLLSSPMKFNALSGFDLE
HHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEE
ITEYVDADS
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]