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The map label for this gene is hdfR [H]

Identifier: 110834984

GI number: 110834984

Start: 2427423

End: 2428262

Strand: Reverse

Name: hdfR [H]

Synonym: ABO_2123

Alternate gene names: 110834984

Gene position: 2428262-2427423 (Counterclockwise)

Preceding gene: 110834992

Following gene: 110834983

Centisome position: 77.83

GC content: 59.05

Gene sequence:

>840_bases
TTGGATATTGATCTGGCCCGTACCTTTTTGGAAATCGTTCGCACCGGCAGCTTTATGGCAGCGGCGGATCGGTTGCACAT
AACCCAGACTACAGTTACAGCGCGGGTGCAGAACCTGGAAGGGCAGCTGGGGTGCCGGCTGTTTGTGCGTAACCGCAGCG
GGGCGACGCTGACGGATCACGGAGAGCGGTTTGCCAGCCATGCCAGCCAGCTGGTTCAGACCTGGGAAGCTGCCCGCAGG
GAGCTGCCGTTACCGCAGGGCGCTGAATCAGTGCTGACATTGGGGGCGGAGATCAGCCTGTGGAATCCACTGCTGCTCAA
CTGGCTATCGGCGCTGCGGGAGGTGTTGCCGGATGTGGCTTTGCGTATTGAGGTGGGCGAGCCCCGTTCATTGCATGAGC
GGCTGGAGCAGAGCGTGCTGGATGCGGTGCTGGTTCATCAGCCGGATTACTGGCCCGGTATGCAGGTGGAGCAGTTGCTT
GAAGAGAAACTGATTCTGGTCCGCACCTCCCACACGGCGGAGCCCTATGTATATGTGGATTGGGGGGCGCATTTTCGCCA
GCAACACGATGTGGCGCAGCCGGAAAAGGCCCGTGCCGGCCTAACTATGGATTTGGGGCCGCTGGCGATTCAGTACCTAG
TGGCTAATGGGGGTAGTGGCTATTTCCGAACCCGTGTTGCTCAGCCATATTTGGAAAACGGGGCGCTGATTCGCGAAACC
GACGCCCCCGAGTTCAGTTACCCGGTGTTTCTGGTGTATTCCCGTGCCAGAAAAAGCGTGCAGCTGGAAAGTGCCTTCTC
TGTGTTGCAGACCACACTGGATGATCAGCCGCAGTGGTAA

Upstream 100 bases:

>100_bases
GTATGAAGGCTCTTTTTTATAGGAAATAATGAAATATAAGGGGATTTAATATCGAAGATGTTGATATAAGTTTGGTTTGA
GCTTGTGTGAGGAGCCCCCA

Downstream 100 bases:

>100_bases
CAGTGAGATGGCGCTGGGGTGTGAGGATTATAGTGTTTCTGCGCGCCGTTCTATGAGAAACCGCTCTTAAGTGAAAATTC
GCGAAAATAATTTTCTCAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDIDLARTFLEIVRTGSFMAAADRLHITQTTVTARVQNLEGQLGCRLFVRNRSGATLTDHGERFASHASQLVQTWEAARR
ELPLPQGAESVLTLGAEISLWNPLLLNWLSALREVLPDVALRIEVGEPRSLHERLEQSVLDAVLVHQPDYWPGMQVEQLL
EEKLILVRTSHTAEPYVYVDWGAHFRQQHDVAQPEKARAGLTMDLGPLAIQYLVANGGSGYFRTRVAQPYLENGALIRET
DAPEFSYPVFLVYSRARKSVQLESAFSVLQTTLDDQPQW

Sequences:

>Translated_279_residues
MDIDLARTFLEIVRTGSFMAAADRLHITQTTVTARVQNLEGQLGCRLFVRNRSGATLTDHGERFASHASQLVQTWEAARR
ELPLPQGAESVLTLGAEISLWNPLLLNWLSALREVLPDVALRIEVGEPRSLHERLEQSVLDAVLVHQPDYWPGMQVEQLL
EEKLILVRTSHTAEPYVYVDWGAHFRQQHDVAQPEKARAGLTMDLGPLAIQYLVANGGSGYFRTRVAQPYLENGALIRET
DAPEFSYPVFLVYSRARKSVQLESAFSVLQTTLDDQPQW
>Mature_279_residues
MDIDLARTFLEIVRTGSFMAAADRLHITQTTVTARVQNLEGQLGCRLFVRNRSGATLTDHGERFASHASQLVQTWEAARR
ELPLPQGAESVLTLGAEISLWNPLLLNWLSALREVLPDVALRIEVGEPRSLHERLEQSVLDAVLVHQPDYWPGMQVEQLL
EEKLILVRTSHTAEPYVYVDWGAHFRQQHDVAQPEKARAGLTMDLGPLAIQYLVANGGSGYFRTRVAQPYLENGALIRET
DAPEFSYPVFLVYSRARKSVQLESAFSVLQTTLDDQPQW

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=263, Percent_Identity=28.8973384030418, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788297, Length=171, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788626, Length=157, Percent_Identity=29.2993630573248, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31427; Mature: 31427

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDLARTFLEIVRTGSFMAAADRLHITQTTVTARVQNLEGQLGCRLFVRNRSGATLTDH
CCHHHHHHHHHHHHCCCHHHHHHHEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCEECHH
GERFASHASQLVQTWEAARRELPLPQGAESVLTLGAEISLWNPLLLNWLSALREVLPDVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHE
LRIEVGEPRSLHERLEQSVLDAVLVHQPDYWPGMQVEQLLEEKLILVRTSHTAEPYVYVD
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCEEEEEECCCCCCEEEEE
WGAHFRQQHDVAQPEKARAGLTMDLGPLAIQYLVANGGSGYFRTRVAQPYLENGALIRET
CCHHHHHHCCCCCCHHHHCCCEECHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCCEEEEC
DAPEFSYPVFLVYSRARKSVQLESAFSVLQTTLDDQPQW
CCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDIDLARTFLEIVRTGSFMAAADRLHITQTTVTARVQNLEGQLGCRLFVRNRSGATLTDH
CCHHHHHHHHHHHHCCCHHHHHHHEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCEECHH
GERFASHASQLVQTWEAARRELPLPQGAESVLTLGAEISLWNPLLLNWLSALREVLPDVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHE
LRIEVGEPRSLHERLEQSVLDAVLVHQPDYWPGMQVEQLLEEKLILVRTSHTAEPYVYVD
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCEEEEEECCCCCCEEEEE
WGAHFRQQHDVAQPEKARAGLTMDLGPLAIQYLVANGGSGYFRTRVAQPYLENGALIRET
CCHHHHHHCCCCCCHHHHCCCEECHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCCEEEEC
DAPEFSYPVFLVYSRARKSVQLESAFSVLQTTLDDQPQW
CCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA