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The map label for this gene is fadE [H]

Identifier: 110834959

GI number: 110834959

Start: 2403448

End: 2405229

Strand: Reverse

Name: fadE [H]

Synonym: ABO_2098

Alternate gene names: 110834959

Gene position: 2405229-2403448 (Counterclockwise)

Preceding gene: 110834962

Following gene: 110834956

Centisome position: 77.09

GC content: 55.67

Gene sequence:

>1782_bases
GTGCAAATGGCGACTTATAAAGCCCCCCTCGAGGACATGCGTTTTGTTCTCAACGATGTGTTCAAAGCGGATCAACTCTG
GGCCTCCATGCCGGCCACCGCAGAGGTGACTCAGGATTTGTCCGATGCGATTCTGGAAGAAGCGGGCAAAATGACCGAAG
GCTTGCTGTTCCCGCTGAATCGTAACAGCGATGAGCAGGGCTGCACTTGGACCGATGGGGCGGTGACTACCCCGGATGGT
TTCAAGGAAGCATTCAAGACCTTTGCCGAAAATGGTTGGAGCGCATTTTCCGGTAACCCGGAGTTTGGTGGCCAGGGTAT
GCCCAAGTCATTGGCGGTGCTTTTTGAAGAAATGATGCACAGCGCTTGTTCTTCGTTTGCCTTGTATCCGGCACTAACCA
GTGGTGCGTGCCTAGCGGTGGATGCCCACGCTTGCGAAGAACTCAAGTCGCAGTACTTACCCAAGCTTTATAGCGGTGAG
TGGAGTGGCACCATGTGCCTGACTGAGCCGCATTCCGGGACAGACCTGGGTATTCTACGGACCAAGGCTGTGCCTAACGA
TGATGGCTCGTTCAACATTACCGGCACCAAGATTTTTATCACCGGTGGTGAACATGACCTGACCGGCAACCATGTCCATC
TGGTGCTGGCTAAGTTGCCGGATGCGCCAGCAGGCTCCAAAGGGATCTCCCTGTTCCTGGTGCCCAAGTTTTTGCCTGAC
GCGGACAACAATCCGGGTGAGGCCAACGGTGTCACCTGTGGTTCCATCGAACATAAGATGGGGATCAAGGGCTCTGCCAC
CTGTGTTATGAACTTCGACGATGCCAAAGGCTGGATTATCGGTGAGCCGAACCAGGGGCTGGCGTGCATGTTCACTATGA
TGAACTACGAGCGACTGTCCATCGGGCTACAGGGCTTGGGGTTGGGTGAAGTTAGCTACCAGAGTGCTGTGGAATATGCG
CGAGAGCGCCTACAAGGTCGCAGCGCCACCGGTGCGAAAAACCCGCAAGGACCGGCGGATCCGATCATTGTGCACGGTGA
TGTGCGTCGCATGCTGATGAACATGCGCGCCATCAATGAAGGAGGCCGTGCGCTGGCAGCCTATGTGGGCATGCAGCTGG
ATACGTCTAAGTTCAGCGAAGACGCGGAGGCCAAGAAGAAAGCGGAGGATCGGGTGGCGCTGTTGACGCCGGTCGCTAAA
GCTTTCTTTACCGATCGAGGCCTGGACACCACCATTACCGGGCAGCAGGTATTTGGGGGCCACGGTTATATTCGTGAATG
GGGTATGGAGCAGTTTGTTCGCGATTGCCGTATTTCCCAGATCTACGAAGGCACTAACGGTATTCAAGCGTTGGACTTAG
CTGGCCGTAAAGTGGTCCGCAACGGTGGTAAATCCGTGGATGCTTTCCTGGCCGATGCCCAGGCCTGGGTGGATGCTAAT
GCCGATAATGCGCAGCTAGCCGCAGTAAAAGACGACCTGCAAGCGGCTTTGCTATTGCTGAAATCTTCCACCGATACACT
GCTGGCCCAGGCCGGCAACAACCCGGATGCGATCAGCGCTGCTGCGGTGGAGTACCTGGATATCTTTGGTTATGTGCTCT
ACGCATGGCTGTGGGCGCAGATGCTAGCGGCCACCGATGACCGTGATGATGACTTCGCTAAAGCCAAACGTATCACCGGG
CAATACTACTTTCAGCGTGTACTGCCAAAGGCCCAATCACTGGCTGCCCAGCTGAATAGCGGTGCGGATGCCATGATGAG
CCTGGACGCGGAACAGTTCTGA

Upstream 100 bases:

>100_bases
CATAAAGCAAAATACGTAATGTGAACGCTGGGTCACAAATAAGCCTGTCACCCAGCTGCAGGGCTGCCTAAAATTCGCAT
CCTGCCAACTTTCGGGAGAC

Downstream 100 bases:

>100_bases
GTGACAAGTTGAAGGTTCAACGTTAGAACGCGGGAGCAATTTCCCCGTACTGAAATCAAGAGGCCGCGCCCTGTGTTTGG
GTGCGGCCTCTTGCGTTAAA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MQMATYKAPLEDMRFVLNDVFKADQLWASMPATAEVTQDLSDAILEEAGKMTEGLLFPLNRNSDEQGCTWTDGAVTTPDG
FKEAFKTFAENGWSAFSGNPEFGGQGMPKSLAVLFEEMMHSACSSFALYPALTSGACLAVDAHACEELKSQYLPKLYSGE
WSGTMCLTEPHSGTDLGILRTKAVPNDDGSFNITGTKIFITGGEHDLTGNHVHLVLAKLPDAPAGSKGISLFLVPKFLPD
ADNNPGEANGVTCGSIEHKMGIKGSATCVMNFDDAKGWIIGEPNQGLACMFTMMNYERLSIGLQGLGLGEVSYQSAVEYA
RERLQGRSATGAKNPQGPADPIIVHGDVRRMLMNMRAINEGGRALAAYVGMQLDTSKFSEDAEAKKKAEDRVALLTPVAK
AFFTDRGLDTTITGQQVFGGHGYIREWGMEQFVRDCRISQIYEGTNGIQALDLAGRKVVRNGGKSVDAFLADAQAWVDAN
ADNAQLAAVKDDLQAALLLLKSSTDTLLAQAGNNPDAISAAAVEYLDIFGYVLYAWLWAQMLAATDDRDDDFAKAKRITG
QYYFQRVLPKAQSLAAQLNSGADAMMSLDAEQF

Sequences:

>Translated_593_residues
MQMATYKAPLEDMRFVLNDVFKADQLWASMPATAEVTQDLSDAILEEAGKMTEGLLFPLNRNSDEQGCTWTDGAVTTPDG
FKEAFKTFAENGWSAFSGNPEFGGQGMPKSLAVLFEEMMHSACSSFALYPALTSGACLAVDAHACEELKSQYLPKLYSGE
WSGTMCLTEPHSGTDLGILRTKAVPNDDGSFNITGTKIFITGGEHDLTGNHVHLVLAKLPDAPAGSKGISLFLVPKFLPD
ADNNPGEANGVTCGSIEHKMGIKGSATCVMNFDDAKGWIIGEPNQGLACMFTMMNYERLSIGLQGLGLGEVSYQSAVEYA
RERLQGRSATGAKNPQGPADPIIVHGDVRRMLMNMRAINEGGRALAAYVGMQLDTSKFSEDAEAKKKAEDRVALLTPVAK
AFFTDRGLDTTITGQQVFGGHGYIREWGMEQFVRDCRISQIYEGTNGIQALDLAGRKVVRNGGKSVDAFLADAQAWVDAN
ADNAQLAAVKDDLQAALLLLKSSTDTLLAQAGNNPDAISAAAVEYLDIFGYVLYAWLWAQMLAATDDRDDDFAKAKRITG
QYYFQRVLPKAQSLAAQLNSGADAMMSLDAEQF
>Mature_593_residues
MQMATYKAPLEDMRFVLNDVFKADQLWASMPATAEVTQDLSDAILEEAGKMTEGLLFPLNRNSDEQGCTWTDGAVTTPDG
FKEAFKTFAENGWSAFSGNPEFGGQGMPKSLAVLFEEMMHSACSSFALYPALTSGACLAVDAHACEELKSQYLPKLYSGE
WSGTMCLTEPHSGTDLGILRTKAVPNDDGSFNITGTKIFITGGEHDLTGNHVHLVLAKLPDAPAGSKGISLFLVPKFLPD
ADNNPGEANGVTCGSIEHKMGIKGSATCVMNFDDAKGWIIGEPNQGLACMFTMMNYERLSIGLQGLGLGEVSYQSAVEYA
RERLQGRSATGAKNPQGPADPIIVHGDVRRMLMNMRAINEGGRALAAYVGMQLDTSKFSEDAEAKKKAEDRVALLTPVAK
AFFTDRGLDTTITGQQVFGGHGYIREWGMEQFVRDCRISQIYEGTNGIQALDLAGRKVVRNGGKSVDAFLADAQAWVDAN
ADNAQLAAVKDDLQAALLLLKSSTDTLLAQAGNNPDAISAAAVEYLDIFGYVLYAWLWAQMLAATDDRDDDFAKAKRITG
QYYFQRVLPKAQSLAAQLNSGADAMMSLDAEQF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=362, Percent_Identity=30.1104972375691, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI4501859, Length=382, Percent_Identity=25.9162303664921, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=25.7978723404255, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958414, Length=376, Percent_Identity=26.5957446808511, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=26.2734584450402, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI21361497, Length=389, Percent_Identity=29.0488431876607, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4557235, Length=315, Percent_Identity=29.5238095238095, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI76496475, Length=315, Percent_Identity=29.5238095238095, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4501857, Length=355, Percent_Identity=25.3521126760563, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4557231, Length=359, Percent_Identity=25.0696378830084, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI187960098, Length=359, Percent_Identity=25.0696378830084, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI87082384, Length=333, Percent_Identity=26.7267267267267, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=24.6113989637306, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=420, Percent_Identity=26.1904761904762, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=29.144385026738, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=30.5630026809651, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=362, Percent_Identity=28.7292817679558, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=26.1780104712042, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=28.1081081081081, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=372, Percent_Identity=24.7311827956989, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI86563383, Length=420, Percent_Identity=25.2380952380952, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86563381, Length=420, Percent_Identity=25.2380952380952, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=387, Percent_Identity=26.6149870801034, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=240, Percent_Identity=30, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=30.4347826086957, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=371, Percent_Identity=24.2587601078167, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=258, Percent_Identity=29.0697674418605, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=27.1276595744681, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281363737, Length=316, Percent_Identity=27.5316455696203, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355753, Length=395, Percent_Identity=26.5822784810127, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=26.525198938992, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646207, Length=388, Percent_Identity=25, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24660351, Length=316, Percent_Identity=26.8987341772152, Blast_Score=88, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 63980; Mature: 63980

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMATYKAPLEDMRFVLNDVFKADQLWASMPATAEVTQDLSDAILEEAGKMTEGLLFPLN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCEEEECC
RNSDEQGCTWTDGAVTTPDGFKEAFKTFAENGWSAFSGNPEFGGQGMPKSLAVLFEEMMH
CCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SACSSFALYPALTSGACLAVDAHACEELKSQYLPKLYSGEWSGTMCLTEPHSGTDLGILR
HHHHHCCHHHHHCCCCEEEECHHHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCCEEEEE
TKAVPNDDGSFNITGTKIFITGGEHDLTGNHVHLVLAKLPDAPAGSKGISLFLVPKFLPD
ECCCCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCC
ADNNPGEANGVTCGSIEHKMGIKGSATCVMNFDDAKGWIIGEPNQGLACMFTMMNYERLS
CCCCCCCCCCEEECCCHHHCCCCCCEEEEEEECCCCCCEEECCCCCCEEEHHHHCHHHHH
IGLQGLGLGEVSYQSAVEYARERLQGRSATGAKNPQGPADPIIVHGDVRRMLMNMRAINE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCC
GGRALAAYVGMQLDTSKFSEDAEAKKKAEDRVALLTPVAKAFFTDRGLDTTITGQQVFGG
CCHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCCEECC
HGYIREWGMEQFVRDCRISQIYEGTNGIQALDLAGRKVVRNGGKSVDAFLADAQAWVDAN
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
ADNAQLAAVKDDLQAALLLLKSSTDTLLAQAGNNPDAISAAAVEYLDIFGYVLYAWLWAQ
CCCCEEEHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLAATDDRDDDFAKAKRITGQYYFQRVLPKAQSLAAQLNSGADAMMSLDAEQF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
>Mature Secondary Structure
MQMATYKAPLEDMRFVLNDVFKADQLWASMPATAEVTQDLSDAILEEAGKMTEGLLFPLN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCEEEECC
RNSDEQGCTWTDGAVTTPDGFKEAFKTFAENGWSAFSGNPEFGGQGMPKSLAVLFEEMMH
CCCCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SACSSFALYPALTSGACLAVDAHACEELKSQYLPKLYSGEWSGTMCLTEPHSGTDLGILR
HHHHHCCHHHHHCCCCEEEECHHHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCCEEEEE
TKAVPNDDGSFNITGTKIFITGGEHDLTGNHVHLVLAKLPDAPAGSKGISLFLVPKFLPD
ECCCCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCC
ADNNPGEANGVTCGSIEHKMGIKGSATCVMNFDDAKGWIIGEPNQGLACMFTMMNYERLS
CCCCCCCCCCEEECCCHHHCCCCCCEEEEEEECCCCCCEEECCCCCCEEEHHHHCHHHHH
IGLQGLGLGEVSYQSAVEYARERLQGRSATGAKNPQGPADPIIVHGDVRRMLMNMRAINE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCC
GGRALAAYVGMQLDTSKFSEDAEAKKKAEDRVALLTPVAKAFFTDRGLDTTITGQQVFGG
CCHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCCEECC
HGYIREWGMEQFVRDCRISQIYEGTNGIQALDLAGRKVVRNGGKSVDAFLADAQAWVDAN
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
ADNAQLAAVKDDLQAALLLLKSSTDTLLAQAGNNPDAISAAAVEYLDIFGYVLYAWLWAQ
CCCCEEEHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLAATDDRDDDFAKAKRITGQYYFQRVLPKAQSLAAQLNSGADAMMSLDAEQF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]