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The map label for this gene is trpC [H]

Identifier: 110834885

GI number: 110834885

Start: 2312926

End: 2313720

Strand: Reverse

Name: trpC [H]

Synonym: ABO_2024

Alternate gene names: 110834885

Gene position: 2313720-2312926 (Counterclockwise)

Preceding gene: 110834886

Following gene: 110834883

Centisome position: 74.15

GC content: 53.21

Gene sequence:

>795_bases
ATGAGCACAGGCACCATTCTCGATAAGATTATCGCCCGCAAGCAGGAGGAGATTGCCATTGGCAAGAACCATTATACGCT
GGGTGATCTACAGTCCATGGCAGACAACCAGCGCAAGGCACGAGGGTTTATTTCCAGCCTATTCGGCCGGGTGAAGGAGC
ATCAGCCAGCGGTGATTGCGGAGATCAAAAAGGCCTCTCCCAGCAAGGGCGTGATCCGAAATGATTTTGATCCGGTATCC
ATTGCCCGCAGCTACGAAGCTAACGGTGCGGCTTGTCTGTCGGTACTTACTGACAAGGATTTTTTCCAGGGCGATGAACA
TTACTTACGTGCAGCTCGTAACGCGGTAAACCTGCCGGTGTTGCGCAAGGATTTCATGATTGATCCGTGGCAGATTTTTG
AGTCCCGAGCCATGGGGGCAGATGCGGTGTTGTTGATTGCGGCAGCGCTGTCCGATGCGCAGATGGATGAGTTATATCAT
GCTGCTCAACAGGCCGGATGCGACGTGTTAGTGGAAGTGCACACGGAAGAGGAATTGCAGCGGGCGATAGCGTTGAACGC
AGAGCTCATCGGCATCAACAACCGTAATCTGCATACCTTCGAGACCAGCCTGAATACTACGTTGACTCTGGCTCAACAGG
TGCCGGGTGACCGTATGGTGGTGACTGAAAGTGGAATCCACTCCAGTGCAGACGTGAAGCTGATGCGTAACAACGGCATC
CATAGTTTCCTGGTCGGCGAAGCCTTTATGCGTGCCGATGACCCGGGCGCTGAACTCAAGAAACTGTTCTTCTGA

Upstream 100 bases:

>100_bases
ACCTGATCCACAATGGAGAAGCGGCAGAACGCATGCGCGAGCTGGCCCAGTTCAGCACGGCCCTCAAGGTTGGCGACGAA
TCCCATTAAGGAGCGAGGTT

Downstream 100 bases:

>100_bases
TTTATAGGCCTCGTCGTTTCAATTGAGTGTTGTTGGGCAGTGCAAGCCGGTAGGCGGTGGTTAGCTTGAGGTATTGTTTT
TAGCGTCCACGTTTTCAGGC

Product: indole-3-glycerol phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSTGTILDKIIARKQEEIAIGKNHYTLGDLQSMADNQRKARGFISSLFGRVKEHQPAVIAEIKKASPSKGVIRNDFDPVS
IARSYEANGAACLSVLTDKDFFQGDEHYLRAARNAVNLPVLRKDFMIDPWQIFESRAMGADAVLLIAAALSDAQMDELYH
AAQQAGCDVLVEVHTEEELQRAIALNAELIGINNRNLHTFETSLNTTLTLAQQVPGDRMVVTESGIHSSADVKLMRNNGI
HSFLVGEAFMRADDPGAELKKLFF

Sequences:

>Translated_264_residues
MSTGTILDKIIARKQEEIAIGKNHYTLGDLQSMADNQRKARGFISSLFGRVKEHQPAVIAEIKKASPSKGVIRNDFDPVS
IARSYEANGAACLSVLTDKDFFQGDEHYLRAARNAVNLPVLRKDFMIDPWQIFESRAMGADAVLLIAAALSDAQMDELYH
AAQQAGCDVLVEVHTEEELQRAIALNAELIGINNRNLHTFETSLNTTLTLAQQVPGDRMVVTESGIHSSADVKLMRNNGI
HSFLVGEAFMRADDPGAELKKLFF
>Mature_263_residues
STGTILDKIIARKQEEIAIGKNHYTLGDLQSMADNQRKARGFISSLFGRVKEHQPAVIAEIKKASPSKGVIRNDFDPVSI
ARSYEANGAACLSVLTDKDFFQGDEHYLRAARNAVNLPVLRKDFMIDPWQIFESRAMGADAVLLIAAALSDAQMDELYHA
AQQAGCDVLVEVHTEEELQRAIALNAELIGINNRNLHTFETSLNTTLTLAQQVPGDRMVVTESGIHSSADVKLMRNNGIH
SFLVGEAFMRADDPGAELKKLFF

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=262, Percent_Identity=40.8396946564886, Blast_Score=168, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322638, Length=264, Percent_Identity=37.5, Blast_Score=161, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 29097; Mature: 28966

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGTILDKIIARKQEEIAIGKNHYTLGDLQSMADNQRKARGFISSLFGRVKEHQPAVIA
CCCHHHHHHHHHCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EIKKASPSKGVIRNDFDPVSIARSYEANGAACLSVLTDKDFFQGDEHYLRAARNAVNLPV
HHHHCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCC
LRKDFMIDPWQIFESRAMGADAVLLIAAALSDAQMDELYHAAQQAGCDVLVEVHTEEELQ
HHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEECCHHHHH
RAIALNAELIGINNRNLHTFETSLNTTLTLAQQVPGDRMVVTESGIHSSADVKLMRNNGI
HHHHCCCEEEECCCCCCEEEECCCCHHEEEHHHCCCCEEEEEECCCCCCCCEEEEECCCC
HSFLVGEAFMRADDPGAELKKLFF
HHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
STGTILDKIIARKQEEIAIGKNHYTLGDLQSMADNQRKARGFISSLFGRVKEHQPAVIA
CCHHHHHHHHHCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EIKKASPSKGVIRNDFDPVSIARSYEANGAACLSVLTDKDFFQGDEHYLRAARNAVNLPV
HHHHCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCC
LRKDFMIDPWQIFESRAMGADAVLLIAAALSDAQMDELYHAAQQAGCDVLVEVHTEEELQ
HHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEECCHHHHH
RAIALNAELIGINNRNLHTFETSLNTTLTLAQQVPGDRMVVTESGIHSSADVKLMRNNGI
HHHHCCCEEEECCCCCCEEEECCCCHHEEEHHHCCCCEEEEEECCCCCCCCEEEEECCCC
HSFLVGEAFMRADDPGAELKKLFF
HHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA