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The map label for this gene is speD

Identifier: 110834882

GI number: 110834882

Start: 2310340

End: 2311170

Strand: Reverse

Name: speD

Synonym: ABO_2021

Alternate gene names: 110834882

Gene position: 2311170-2310340 (Counterclockwise)

Preceding gene: 110834883

Following gene: 110834880

Centisome position: 74.07

GC content: 47.77

Gene sequence:

>831_bases
ATGAAACGCCCATGGGGTAAGGCTGTGGTGAAAGATCCCAATCCCAAGATTACGGTTCACGGTTTCAATAACCTGACCAA
ATCCTTGAGTTTTAATATTTTTGATATCGCTTACGCAAAGACAGAACAGCACCGTCAGGAATATATCGAATATATTGACG
AGCTGTATAACGCGGAGCGTCTCACCGAGATTCTCACCAACGTAACCAATATCATTGGCGCCAATATTTTGAATGTGGCT
CGCCAGGATTATGAGCCTCAGGGTGCCAGTGTGACCATGCTGATTGCTGAGCATGAAACTCCACCTGTTGGGACCGACTG
GGACGAAGAAGGGCCAGGGCCGTTGCCAGAGACGGTCGTTGCTCATCTGGATAAGAGCCATGTGACGGTACATACCTATC
CTGAGTCGCACCCGGATAATGGCATCTCCACTTTTCGGGTCGATGTGGACGTGTCGACCTGTGGGGTAATCTCCCCGCTG
CGTGCGTTGAACTACCTAATCCACAGTTTCGATTCCGATATTGTCACGGTGGATTACCGGGTGCGTGGAATGACTCGTGA
TCTGGATGGCACCAAGCACTACATTGATCACGATATTAATTCGATCCAGAACTTCCTGACTGAAGATACCCAGAACGCTT
ATCAGATGATCGACGTGAATGTGTATCAGGAAAATATCTTCCACACCAAGATGTTGCTGAAAGACTTCGATATTGATAAC
TACTTGTTTGGCGCCGGTAGGGATGAATTCGCACAAACCGAGTTAGACCAGATTGAAGAGCGGATGAAGACTGAGATGCT
GGAGATTTTCTACAGCCGTAACTTGGGATAA

Upstream 100 bases:

>100_bases
CAATATGCCGGCCAGGCCGGTGATTGTGGTGACATCCTTTGGGATGTTGCAAACAAGGTAGCCGCTAGGGTTGCGGTGGT
GTGTTTGTCTTAACGTGGCG

Downstream 100 bases:

>100_bases
GCCTGCAGCAAGCTTCCACGTAACACGCAGAATAAAAAAGCCGCGCCCGTACAGGGTGCGGCTTTTTTTGTTGCTGGACG
CCGGCTACAGAGTGGTTAGA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKRPWGKAVVKDPNPKITVHGFNNLTKSLSFNIFDIAYAKTEQHRQEYIEYIDELYNAERLTEILTNVTNIIGANILNVA
RQDYEPQGASVTMLIAEHETPPVGTDWDEEGPGPLPETVVAHLDKSHVTVHTYPESHPDNGISTFRVDVDVSTCGVISPL
RALNYLIHSFDSDIVTVDYRVRGMTRDLDGTKHYIDHDINSIQNFLTEDTQNAYQMIDVNVYQENIFHTKMLLKDFDIDN
YLFGAGRDEFAQTELDQIEERMKTEMLEIFYSRNLG

Sequences:

>Translated_276_residues
MKRPWGKAVVKDPNPKITVHGFNNLTKSLSFNIFDIAYAKTEQHRQEYIEYIDELYNAERLTEILTNVTNIIGANILNVA
RQDYEPQGASVTMLIAEHETPPVGTDWDEEGPGPLPETVVAHLDKSHVTVHTYPESHPDNGISTFRVDVDVSTCGVISPL
RALNYLIHSFDSDIVTVDYRVRGMTRDLDGTKHYIDHDINSIQNFLTEDTQNAYQMIDVNVYQENIFHTKMLLKDFDIDN
YLFGAGRDEFAQTELDQIEERMKTEMLEIFYSRNLG
>Mature_276_residues
MKRPWGKAVVKDPNPKITVHGFNNLTKSLSFNIFDIAYAKTEQHRQEYIEYIDELYNAERLTEILTNVTNIIGANILNVA
RQDYEPQGASVTMLIAEHETPPVGTDWDEEGPGPLPETVVAHLDKSHVTVHTYPESHPDNGISTFRVDVDVSTCGVISPL
RALNYLIHSFDSDIVTVDYRVRGMTRDLDGTKHYIDHDINSIQNFLTEDTQNAYQMIDVNVYQENIFHTKMLLKDFDIDN
YLFGAGRDEFAQTELDQIEERMKTEMLEIFYSRNLG

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786311, Length=260, Percent_Identity=65.3846153846154, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPED_ALCBS (Q0VMX9)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693741.1
- ProteinModelPortal:   Q0VMX9
- STRING:   Q0VMX9
- GeneID:   4213642
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2021
- NMPDR:   fig|393595.12.peg.2023
- eggNOG:   COG1586
- HOGENOM:   HBG303125
- OMA:   YNAERLT
- PhylomeDB:   Q0VMX9
- ProtClustDB:   PRK05462
- BioCyc:   ABOR393595:ABO_2021-MONOMER
- HAMAP:   MF_00465
- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067
- Gene3D:   G3DSA:3.60.90.10
- PIRSF:   PIRSF001356
- TIGRFAMs:   TIGR03331

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 31647; Mature: 31647

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: ACT_SITE 126-126 ACT_SITE 131-131 ACT_SITE 154-154

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPWGKAVVKDPNPKITVHGFNNLTKSLSFNIFDIAYAKTEQHRQEYIEYIDELYNAER
CCCCCCCCEEECCCCEEEEECCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCHHH
LTEILTNVTNIIGANILNVARQDYEPQGASVTMLIAEHETPPVGTDWDEEGPGPLPETVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHH
AHLDKSHVTVHTYPESHPDNGISTFRVDVDVSTCGVISPLRALNYLIHSFDSDIVTVDYR
HHCCCCCEEEEECCCCCCCCCCEEEEEEECCHHCCHHHHHHHHHHHHHHCCCCEEEEEEE
VRGMTRDLDGTKHYIDHDINSIQNFLTEDTQNAYQMIDVNVYQENIFHTKMLLKDFDIDN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEHHHHHHHHHHHHHHHCCCCC
YLFGAGRDEFAQTELDQIEERMKTEMLEIFYSRNLG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRPWGKAVVKDPNPKITVHGFNNLTKSLSFNIFDIAYAKTEQHRQEYIEYIDELYNAER
CCCCCCCCEEECCCCEEEEECCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCHHH
LTEILTNVTNIIGANILNVARQDYEPQGASVTMLIAEHETPPVGTDWDEEGPGPLPETVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHH
AHLDKSHVTVHTYPESHPDNGISTFRVDVDVSTCGVISPLRALNYLIHSFDSDIVTVDYR
HHCCCCCEEEEECCCCCCCCCCEEEEEEECCHHCCHHHHHHHHHHHHHHCCCCEEEEEEE
VRGMTRDLDGTKHYIDHDINSIQNFLTEDTQNAYQMIDVNVYQENIFHTKMLLKDFDIDN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEHHHHHHHHHHHHHHHCCCCC
YLFGAGRDEFAQTELDQIEERMKTEMLEIFYSRNLG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA