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The map label for this gene is sulP [C]

Identifier: 110834806

GI number: 110834806

Start: 2222947

End: 2224686

Strand: Direct

Name: sulP [C]

Synonym: ABO_1945

Alternate gene names: 110834806

Gene position: 2222947-2224686 (Clockwise)

Preceding gene: 110834805

Following gene: 110834808

Centisome position: 71.25

GC content: 57.59

Gene sequence:

>1740_bases
GTGCAGCGAGCCTTGCGAGTAATACGCTGGTTACCCGCCAGCGACTGGCTGGCTCGCTATACCCGCGCCGATGCCGCCGG
TGACGGCTTGGCCGCTATTATCGTGACCATTTTGTTGGTACCCCAGGGGCTGGCATACGCACTCTTGGCGGGTATGCCCC
CTGAAACCGGGCTGTATGCCAGCATGTTGCCTTTGATTGTTTACGGCCTATTCGGCACCAGCAGCAGCCTGTCCGTTGGG
CCGGCGGCACTCACATCACTGATTACCGCCTCCGCCGCCGGCGCCCTCGCCCACGGAGATCCTCAGCTGTTTATCCAGGC
GGCTATTGGCATGGGGCTGCTCTCTGGAGCGGTGCTAATAATAATGGCGGTGTTACGCCTGGGCTGGCTGACTAACCTGC
TTAGTCACCCTGTCATCATCGGTTTTGTAAGTGGCTGTGCCATTTTGATCGCCAGCAGCCAGCTCAAGCACCTGCTGGGC
ATCCCTGCCAGCGGCAATAACATTGTGCAACTGGGCCGCAGTTTGAGCGCACATTTAAATCAGAGTCACTGGCTCACCGT
GGCCATTAGTGCCATCGCCATTGCCTCCCTGCTTATCCCTAAACAACTCAATGGCGCATTCAAGCGTAGCCGTTTACCCG
CTTGGCTCGCCGCCTTCATGGGCAAATCCGGCCCGATTCTGGCGGTGCTGGTCACCACTGTGTTGGCATTTTCCTTCGAC
TTGGATCAACAGGGCTTAGCCATTGTGGGCGCAATCCCCAGCGGCCTGCCCCATCTATCCACCCCACAAATGGACTGGAA
CCACTGGAAGGCCGTGGCAACACCCGCTCTGTTATTAGCGCTGATCGGTTTCGTGGAATCCATTTCTTTGGCACAGGCGC
TGGCTGCCCGCCGCCGGGAGCGAATTTCCCCTAATCGGGAACTGATGGGGCTGGGTTTGGCTAACCTGGCTAGCGGCCTA
TCCGGCTCCTTTGCTGTCACCGGCAGTTTTTCCCGCACCACGGTGAGTTTCGAGGCCGGAGCCCGGACCCCCATGACCAG
CCTGCTCACCGGTATGGGCATTGCCCTGGTGGCCCTGTTTTTCACCGGTCTATTTTACGCTTTACCCTTGGCCACCCTCG
CCGCGATCATTGTGGTGGGCATTATTCCTTTGATCGAACTAGGGGAAATTCGCCAGCTATGGCGATACAGCCGTCCGGAT
AGCATCGCTATGGTGGTCACCTTATTCGGGGTGTTATTAATCAATGTGCAAAGCGGCTTGCTTATCGGAGTAGGATTGTC
CGTGGTGCTGTTCTTGTGGCGCACCAGCCAACCCCATGTGGCCGAAGTCGGCCTGGTGCCCGGCACACAGCATTTTCGTA
ACATTGACCGTCACGACGCCATTATCTCCGATCAGATTCTGTCCATACGCGTGGATGAGTCACTGTATTTTGGGAATGCT
CGGCCACTGGAGGATCTGCTCTACGATCATGCCATGGGCCGTCCCGGTGTTGCTCATGTGGTGCTGATGTGCTCCGCCAT
CAATCACTTGGATGCCAGTGCTGTACAGAGCCTAGAAAGCCTCAACGCGCGGCTCGACGCCGCCGGCGTACAGTTACATC
TATCTGAAGTAAAAGGCCCAGTGATGGACCGGCTGACGAAAACCCACTTGCTGAGCACTCTCAGCGGCCAGGTTTTTCTC
AGCCAATATCAGGCCATTGAAGCGCTCGGCGGAGCCACCAAGACACCTGACGCCGTATAG

Upstream 100 bases:

>100_bases
GAACAAGACAACGCCCGCATTCTTGCCACCGCAGAACAAGCCGGTTACGACCTGAGCGGGCTGGTAGAGCGGCTCGATCA
GCGCCGAGGCCAATAACAAC

Downstream 100 bases:

>100_bases
CACCAAGAAGCGACACGCCTCTTACCCTAGCGTTTACAAAAATCGAGCGTGATACCACACTAGGGCCAACCACTCATACC
AAATCTCCGGCACCATAGAT

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MQRALRVIRWLPASDWLARYTRADAAGDGLAAIIVTILLVPQGLAYALLAGMPPETGLYASMLPLIVYGLFGTSSSLSVG
PAALTSLITASAAGALAHGDPQLFIQAAIGMGLLSGAVLIIMAVLRLGWLTNLLSHPVIIGFVSGCAILIASSQLKHLLG
IPASGNNIVQLGRSLSAHLNQSHWLTVAISAIAIASLLIPKQLNGAFKRSRLPAWLAAFMGKSGPILAVLVTTVLAFSFD
LDQQGLAIVGAIPSGLPHLSTPQMDWNHWKAVATPALLLALIGFVESISLAQALAARRRERISPNRELMGLGLANLASGL
SGSFAVTGSFSRTTVSFEAGARTPMTSLLTGMGIALVALFFTGLFYALPLATLAAIIVVGIIPLIELGEIRQLWRYSRPD
SIAMVVTLFGVLLINVQSGLLIGVGLSVVLFLWRTSQPHVAEVGLVPGTQHFRNIDRHDAIISDQILSIRVDESLYFGNA
RPLEDLLYDHAMGRPGVAHVVLMCSAINHLDASAVQSLESLNARLDAAGVQLHLSEVKGPVMDRLTKTHLLSTLSGQVFL
SQYQAIEALGGATKTPDAV

Sequences:

>Translated_579_residues
MQRALRVIRWLPASDWLARYTRADAAGDGLAAIIVTILLVPQGLAYALLAGMPPETGLYASMLPLIVYGLFGTSSSLSVG
PAALTSLITASAAGALAHGDPQLFIQAAIGMGLLSGAVLIIMAVLRLGWLTNLLSHPVIIGFVSGCAILIASSQLKHLLG
IPASGNNIVQLGRSLSAHLNQSHWLTVAISAIAIASLLIPKQLNGAFKRSRLPAWLAAFMGKSGPILAVLVTTVLAFSFD
LDQQGLAIVGAIPSGLPHLSTPQMDWNHWKAVATPALLLALIGFVESISLAQALAARRRERISPNRELMGLGLANLASGL
SGSFAVTGSFSRTTVSFEAGARTPMTSLLTGMGIALVALFFTGLFYALPLATLAAIIVVGIIPLIELGEIRQLWRYSRPD
SIAMVVTLFGVLLINVQSGLLIGVGLSVVLFLWRTSQPHVAEVGLVPGTQHFRNIDRHDAIISDQILSIRVDESLYFGNA
RPLEDLLYDHAMGRPGVAHVVLMCSAINHLDASAVQSLESLNARLDAAGVQLHLSEVKGPVMDRLTKTHLLSTLSGQVFL
SQYQAIEALGGATKTPDAV
>Mature_579_residues
MQRALRVIRWLPASDWLARYTRADAAGDGLAAIIVTILLVPQGLAYALLAGMPPETGLYASMLPLIVYGLFGTSSSLSVG
PAALTSLITASAAGALAHGDPQLFIQAAIGMGLLSGAVLIIMAVLRLGWLTNLLSHPVIIGFVSGCAILIASSQLKHLLG
IPASGNNIVQLGRSLSAHLNQSHWLTVAISAIAIASLLIPKQLNGAFKRSRLPAWLAAFMGKSGPILAVLVTTVLAFSFD
LDQQGLAIVGAIPSGLPHLSTPQMDWNHWKAVATPALLLALIGFVESISLAQALAARRRERISPNRELMGLGLANLASGL
SGSFAVTGSFSRTTVSFEAGARTPMTSLLTGMGIALVALFFTGLFYALPLATLAAIIVVGIIPLIELGEIRQLWRYSRPD
SIAMVVTLFGVLLINVQSGLLIGVGLSVVLFLWRTSQPHVAEVGLVPGTQHFRNIDRHDAIISDQILSIRVDESLYFGNA
RPLEDLLYDHAMGRPGVAHVVLMCSAINHLDASAVQSLESLNARLDAAGVQLHLSEVKGPVMDRLTKTHLLSTLSGQVFL
SQYQAIEALGGATKTPDAV

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721255, Length=503, Percent_Identity=31.4115308151093, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI94721253, Length=503, Percent_Identity=31.4115308151093, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI94721259, Length=503, Percent_Identity=31.4115308151093, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI94721257, Length=503, Percent_Identity=31.4115308151093, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI45827800, Length=555, Percent_Identity=28.6486486486486, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI39752683, Length=519, Percent_Identity=28.9017341040462, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI262206105, Length=604, Percent_Identity=28.1456953642384, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI262206075, Length=604, Percent_Identity=28.1456953642384, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI262206069, Length=604, Percent_Identity=28.1456953642384, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI262206063, Length=604, Percent_Identity=28.1456953642384, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI100913030, Length=652, Percent_Identity=25.7668711656442, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI47131207, Length=643, Percent_Identity=28.149300155521, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI20336272, Length=643, Percent_Identity=28.149300155521, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI45827802, Length=453, Percent_Identity=29.5805739514349, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI269784651, Length=518, Percent_Identity=27.6061776061776, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI16306483, Length=528, Percent_Identity=27.8409090909091, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI20336282, Length=528, Percent_Identity=27.8409090909091, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI4557535, Length=514, Percent_Identity=26.2645914396887, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI4505697, Length=510, Percent_Identity=23.1372549019608, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI65506789, Length=556, Percent_Identity=29.6762589928058, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI16418457, Length=501, Percent_Identity=25.5489021956088, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI301601599, Length=501, Percent_Identity=25.5489021956088, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI16418413, Length=499, Percent_Identity=24.248496993988, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI217272867, Length=499, Percent_Identity=24.248496993988, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI45827804, Length=269, Percent_Identity=30.1115241635688, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI301601602, Length=181, Percent_Identity=30.3867403314917, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI87081859, Length=545, Percent_Identity=25.8715596330275, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86564196, Length=621, Percent_Identity=25.7648953301127, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17562578, Length=628, Percent_Identity=26.2738853503185, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17551690, Length=561, Percent_Identity=23.5294117647059, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17566848, Length=600, Percent_Identity=25.5, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI86565215, Length=455, Percent_Identity=25.4945054945055, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193203292, Length=515, Percent_Identity=28.1553398058252, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI86564876, Length=541, Percent_Identity=24.9537892791128, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI86565213, Length=272, Percent_Identity=26.8382352941176, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI86565209, Length=250, Percent_Identity=24, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86565211, Length=250, Percent_Identity=24, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319771, Length=502, Percent_Identity=26.0956175298805, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6325260, Length=584, Percent_Identity=24.486301369863, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6323121, Length=464, Percent_Identity=24.3534482758621, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24663084, Length=555, Percent_Identity=30.8108108108108, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI21357695, Length=555, Percent_Identity=30.8108108108108, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24649801, Length=459, Percent_Identity=28.9760348583878, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24651449, Length=553, Percent_Identity=24.2314647377938, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI19922482, Length=537, Percent_Identity=25.6983240223464, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI85815873, Length=538, Percent_Identity=26.0223048327138, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21358229, Length=550, Percent_Identity=25.4545454545455, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI21355087, Length=561, Percent_Identity=26.2032085561497, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24647160, Length=561, Percent_Identity=26.2032085561497, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21358633, Length=466, Percent_Identity=26.1802575107296, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24666186, Length=666, Percent_Identity=22.972972972973, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 61111; Mature: 61111

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRALRVIRWLPASDWLARYTRADAAGDGLAAIIVTILLVPQGLAYALLAGMPPETGLYA
CHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
SMLPLIVYGLFGTSSSLSVGPAALTSLITASAAGALAHGDPQLFIQAAIGMGLLSGAVLI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHH
IMAVLRLGWLTNLLSHPVIIGFVSGCAILIASSQLKHLLGIPASGNNIVQLGRSLSAHLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
QSHWLTVAISAIAIASLLIPKQLNGAFKRSRLPAWLAAFMGKSGPILAVLVTTVLAFSFD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
LDQQGLAIVGAIPSGLPHLSTPQMDWNHWKAVATPALLLALIGFVESISLAQALAARRRE
CCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISPNRELMGLGLANLASGLSGSFAVTGSFSRTTVSFEAGARTPMTSLLTGMGIALVALF
HCCCCHHHHHCCHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
FTGLFYALPLATLAAIIVVGIIPLIELGEIRQLWRYSRPDSIAMVVTLFGVLLINVQSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
LIGVGLSVVLFLWRTSQPHVAEVGLVPGTQHFRNIDRHDAIISDQILSIRVDESLYFGNA
HHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCHHHHHHHHCCEEEEEECCCEEECCC
RPLEDLLYDHAMGRPGVAHVVLMCSAINHLDASAVQSLESLNARLDAAGVQLHLSEVKGP
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHEEEHHHHCCH
VMDRLTKTHLLSTLSGQVFLSQYQAIEALGGATKTPDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQRALRVIRWLPASDWLARYTRADAAGDGLAAIIVTILLVPQGLAYALLAGMPPETGLYA
CHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
SMLPLIVYGLFGTSSSLSVGPAALTSLITASAAGALAHGDPQLFIQAAIGMGLLSGAVLI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHH
IMAVLRLGWLTNLLSHPVIIGFVSGCAILIASSQLKHLLGIPASGNNIVQLGRSLSAHLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
QSHWLTVAISAIAIASLLIPKQLNGAFKRSRLPAWLAAFMGKSGPILAVLVTTVLAFSFD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
LDQQGLAIVGAIPSGLPHLSTPQMDWNHWKAVATPALLLALIGFVESISLAQALAARRRE
CCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISPNRELMGLGLANLASGLSGSFAVTGSFSRTTVSFEAGARTPMTSLLTGMGIALVALF
HCCCCHHHHHCCHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
FTGLFYALPLATLAAIIVVGIIPLIELGEIRQLWRYSRPDSIAMVVTLFGVLLINVQSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCH
LIGVGLSVVLFLWRTSQPHVAEVGLVPGTQHFRNIDRHDAIISDQILSIRVDESLYFGNA
HHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCHHHHHHHHCCEEEEEECCCEEECCC
RPLEDLLYDHAMGRPGVAHVVLMCSAINHLDASAVQSLESLNARLDAAGVQLHLSEVKGP
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHEEEHHHHCCH
VMDRLTKTHLLSTLSGQVFLSQYQAIEALGGATKTPDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]