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The map label for this gene is gap [H]

Identifier: 110834637

GI number: 110834637

Start: 2023476

End: 2024492

Strand: Direct

Name: gap [H]

Synonym: ABO_1776

Alternate gene names: 110834637

Gene position: 2023476-2024492 (Clockwise)

Preceding gene: 110834632

Following gene: 110834641

Centisome position: 64.85

GC content: 55.85

Gene sequence:

>1017_bases
ATGGACAGCAATCCGACCATTCGCATTGCCATCAACGGTTTCGGCCGTATAGGACGCTGCCTAGTTAGGGCCCTCAGCGA
ACATCCAGCCCGGGAGCGTTTTGAACTTGTCGCCATCAACGATCTTGCCGATTTCAATGTACTCGCGCACCTGCTTGCCT
TCGATACCACCCATGGTCGCTGGCCTCATCCTGTGCATTATGACGGCCAAACCATGGAAATTAATGGTCTCAGCGTGCCC
TGCTACGCCATTGCCGATTTGGAAAAATTACCATGGCGTGAACTGGCTCCAGACTTAGTGTTCGAATGCAGCGGCCGCTA
CAAGCAACGAGCACAACTTCAACAGCACCTTGATGCTGGCGCTCGCCGGGTACTTGCAAGCTACCCGGTGGGCGACGCCG
ACGCCATGGTGGTTTATGGCGTCAACCACAAGATTCTTGATGACAATCAACGCATCGTTTCCAACGCCTCATGCACCACC
AACTGTTTGGCTCCGCTGGTAGATGTACTGGACCGCAACTTCACGGTGAAACAGGGGCTAATGACCACGATCCACAGCTA
CACGAACGACCAGAACCTGGTAGACAAGGCCCACGGAGATTTATTGCGCGCCCGCGCCGCGGCAGTCAATATGATTCCAA
CCCGCACCGGCGCAGCTCAAGCCGTAGGAAAAGTGCTGCCTCACCTGGCCGGGCGACTGGACGGAATGGCGGTGCGAGTT
CCCACCCTCAACGTATCATTGGTGGACCTGACATTGCTGCTGGAACAGCCCGCTACGGTGGAGGCGATTCATGACAGCCT
GAACAATGCGGCCCACGGTGACTTGCAGGGGGTATTGGCCATGAACCATCTGGCCCTGGTTTCCAGTGACTTTAACCACC
AACCCTACTCTTGCGTGGTCGACACCAACCACACACGGATATTGGAGCAACAATTAAAAGTGCTGGCCTGGTACGACAAC
GAGTGGGGCTTCAGCCACCGTATGCTGGATGTTGCGGCGTATTGGATGGAACGCTAG

Upstream 100 bases:

>100_bases
GAGCAGGCTGGCCCCAGTCGAGCCGCAAGGCTACACTTGAAAAAGCAAAGTAGGGTCCATCAGACTCTATATCTAACCCC
AGCGCGAACAGGGAGGCTTC

Downstream 100 bases:

>100_bases
GCACAGACAGAGCCAGCCCCGCATCGCCAAAAAGCAGCAGGCATGATGCGGGGACAGGTGACGGTTTATGGACGAGAGGC
CGCGCAAGCCACCCAGCCAT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MDSNPTIRIAINGFGRIGRCLVRALSEHPARERFELVAINDLADFNVLAHLLAFDTTHGRWPHPVHYDGQTMEINGLSVP
CYAIADLEKLPWRELAPDLVFECSGRYKQRAQLQQHLDAGARRVLASYPVGDADAMVVYGVNHKILDDNQRIVSNASCTT
NCLAPLVDVLDRNFTVKQGLMTTIHSYTNDQNLVDKAHGDLLRARAAAVNMIPTRTGAAQAVGKVLPHLAGRLDGMAVRV
PTLNVSLVDLTLLLEQPATVEAIHDSLNNAAHGDLQGVLAMNHLALVSSDFNHQPYSCVVDTNHTRILEQQLKVLAWYDN
EWGFSHRMLDVAAYWMER

Sequences:

>Translated_338_residues
MDSNPTIRIAINGFGRIGRCLVRALSEHPARERFELVAINDLADFNVLAHLLAFDTTHGRWPHPVHYDGQTMEINGLSVP
CYAIADLEKLPWRELAPDLVFECSGRYKQRAQLQQHLDAGARRVLASYPVGDADAMVVYGVNHKILDDNQRIVSNASCTT
NCLAPLVDVLDRNFTVKQGLMTTIHSYTNDQNLVDKAHGDLLRARAAAVNMIPTRTGAAQAVGKVLPHLAGRLDGMAVRV
PTLNVSLVDLTLLLEQPATVEAIHDSLNNAAHGDLQGVLAMNHLALVSSDFNHQPYSCVVDTNHTRILEQQLKVLAWYDN
EWGFSHRMLDVAAYWMER
>Mature_338_residues
MDSNPTIRIAINGFGRIGRCLVRALSEHPARERFELVAINDLADFNVLAHLLAFDTTHGRWPHPVHYDGQTMEINGLSVP
CYAIADLEKLPWRELAPDLVFECSGRYKQRAQLQQHLDAGARRVLASYPVGDADAMVVYGVNHKILDDNQRIVSNASCTT
NCLAPLVDVLDRNFTVKQGLMTTIHSYTNDQNLVDKAHGDLLRARAAAVNMIPTRTGAAQAVGKVLPHLAGRLDGMAVRV
PTLNVSLVDLTLLLEQPATVEAIHDSLNNAAHGDLQGVLAMNHLALVSSDFNHQPYSCVVDTNHTRILEQQLKVLAWYDN
EWGFSHRMLDVAAYWMER

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=41.7910447761194, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI7657116, Length=336, Percent_Identity=41.0714285714286, Blast_Score=251, Evalue=6e-67,
Organism=Escherichia coli, GI1789295, Length=327, Percent_Identity=44.954128440367, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=44.4108761329305, Blast_Score=273, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=41.8879056047198, Blast_Score=267, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=41.8879056047198, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=41.5929203539823, Blast_Score=254, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=41.7910447761194, Blast_Score=253, Evalue=9e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=43.8066465256798, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=43.161094224924, Blast_Score=266, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=42.3780487804878, Blast_Score=264, Evalue=1e-71,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=42.5531914893617, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=41.9161676646707, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=41.9161676646707, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=41.6167664670659, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=41.6167664670659, Blast_Score=262, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37521; Mature: 37521

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSNPTIRIAINGFGRIGRCLVRALSEHPARERFELVAINDLADFNVLAHLLAFDTTHGR
CCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
WPHPVHYDGQTMEINGLSVPCYAIADLEKLPWRELAPDLVFECSGRYKQRAQLQQHLDAG
CCCCCCCCCCEEEECCCCCCHHEECCHHHCCHHHHCHHHHHHCCCCHHHHHHHHHHHHHH
ARRVLASYPVGDADAMVVYGVNHKILDDNQRIVSNASCTTNCLAPLVDVLDRNFTVKQGL
HHHHHHHCCCCCCCEEEEEECCCEEECCCHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
MTTIHSYTNDQNLVDKAHGDLLRARAAAVNMIPTRTGAAQAVGKVLPHLAGRLDGMAVRV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
PTLNVSLVDLTLLLEQPATVEAIHDSLNNAAHGDLQGVLAMNHLALVSSDFNHQPYSCVV
EECCEEHEEHEEHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCCCCEEEEE
DTNHTRILEQQLKVLAWYDNEWGFSHRMLDVAAYWMER
ECCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSNPTIRIAINGFGRIGRCLVRALSEHPARERFELVAINDLADFNVLAHLLAFDTTHGR
CCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
WPHPVHYDGQTMEINGLSVPCYAIADLEKLPWRELAPDLVFECSGRYKQRAQLQQHLDAG
CCCCCCCCCCEEEECCCCCCHHEECCHHHCCHHHHCHHHHHHCCCCHHHHHHHHHHHHHH
ARRVLASYPVGDADAMVVYGVNHKILDDNQRIVSNASCTTNCLAPLVDVLDRNFTVKQGL
HHHHHHHCCCCCCCEEEEEECCCEEECCCHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
MTTIHSYTNDQNLVDKAHGDLLRARAAAVNMIPTRTGAAQAVGKVLPHLAGRLDGMAVRV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
PTLNVSLVDLTLLLEQPATVEAIHDSLNNAAHGDLQGVLAMNHLALVSSDFNHQPYSCVV
EECCEEHEEHEEHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCCCCEEEEE
DTNHTRILEQQLKVLAWYDNEWGFSHRMLDVAAYWMER
ECCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]