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The map label for this gene is metG

Identifier: 110834460

GI number: 110834460

Start: 1829835

End: 1831895

Strand: Direct

Name: metG

Synonym: ABO_1599

Alternate gene names: 110834460

Gene position: 1829835-1831895 (Clockwise)

Preceding gene: 110834459

Following gene: 110834462

Centisome position: 58.65

GC content: 57.25

Gene sequence:

>2061_bases
TTGGAAATTGATGCCGTTCCCATGAGTGACACTCCCCGCAAGATACTGGTCACCAGTGCCCTTCCCTACGCCAATGGCCC
TATTCATCTCGGCCATTTGCTGGAATACATTCAAACGGACATCTGGGTTCGCTTCCAGAAACTCCGTGGCCAGCAATGCA
TCTATGTGTGTGCTGACGACGCCCATGGCACCGCCATCATGCTCAAGGCCGAGGAAAACGGCGTCACCCCGGAACAGCAA
ATCGCCCAGGTGAAAGCCGACCACGAGCGTGATTTCGCCGATTTCCAAGTAAACTTCGACAACTACTACAGCACCCACAG
CCCCGAAAACCGGGCGCTGTCGGAAATGGTATTCCAGCGCAACAAAGATGCGGGCTACATTCTGGAAAAAACCATCACCC
AGCTGTATGACCCGCAGAAAGGCATGTTCCTGGCCGATCGCTTCGTTAAGGGCACCTGCCCCAAATGCAAAAGCGAAGAC
CAGTACGGCGATAACTGCGAAGTGTGCGGCGCCACCTATACCCCTGCGGAGCTGATTGAGCCCTATTCTTCCGTCAGTGG
CGCCACCCCGGTGGAAAAAGAAACCACCCAACTGTTCTTCGACCTGCCCAAGTTCGAAGCCCTGCTGCGCGAGTGGACCC
GCTCCGGCGCCCTGCAGGAACAGGTCGCCAACAAACTGCAGGAATGGATTGAAGACCTGCAGCCCTGGGATATTTCCCGT
GAAGCGCCTTACTTCGGCTTCGAGATCCCCGGCTACCCGGGCAAGTATTTCTATGTGTGGCTCGATGCCCCCATTGGCTA
CATGGCCAGCTTCCAGAATTACTGCGACCGTGAAGGGCTCAGCTTCGACGATTACTGGGGCAAAGAATCCACCGCCGAGC
TGTACCACTTTATCGGCAAGGACATCATCAATTTCCACGGTTTGTTCTGGCCCGCCATGCTAGACGGCGCCGGCTTGCGC
AAGCCCACTGCCATCTACAGCCACGGCTTCGTCACCGTGAACGGCGCCAAGATGTCCAAGTCCCGTGGCACCTTTATCAA
GGCCCGCACCTATCTGGATCACCTGAGCCCGGAATACCTGCGTTACTATTTCGCCGCCAAGCTCTCCAGCCGCGTGGACG
ATTTCGACCTGAACCTGGAAGACTTTGCCCAGCGAGTGAATTCCGACCTGGTGGGCAAACTGGTCAATATCGCCAGCCGT
ACCGGTAACTTCGTCAAGAAGTTCGGCGGCACACTCAGCACCGAGCTAGACAACATGATGCTGGTGCGCGAAGTGCAGGA
AGCAGGCCCGCGCATTGCCGATTTCTACGAGAAGCGCGAATTCGGCAAAGCCATGCGTGAAATTATGGCCCTGGCCGATC
ACGCCAACGTCTACATCGCCGACAAGGCTCCCTGGAGCCTCTCTAAGGAAGAAGGCAAAGAGCAGGAAGTGTTGGCTATA
TGCAGCACCGCCATTAACGTCTTCCGGCTGCTGGTGATCTACCTGAAACCGGTTTTGCCCGCGTTGGCCGAACGCGCCGA
AGCCTTCATGCAGGTGGAGCCGCTCACCTGGGCGGATTCGGAGCAACTGTTACTCGGCCATGAGATTGCCAAGTTCAAGC
CTCTGCTCAGCCGTGTGGATATGGCACAGGTAGAATCCATGCTCGAAGATTCCAAAGAAAGCACACCGGCCCCCGCTGCC
GCCAAGCCTAAAAAGGCCGCCACGCAAAAAGCAGACGCAGCCGACAATGACGAAACCATCAGCATCGATGATTTCCTCAA
GGTGAAATTGCGCGTGGCCCGCGTGGCCAAGGCCGCGCACGTAGACGGTGCCGACAAGTTGTTGCAGCTAACGCTGGACG
TAGGCGAGCTGGGTCAACGCAATGTGTTTGCCGGCATCAAGGCCCGTTACGCACCGGAGGAGCTGGAAGGCAAGCTGGTC
GTATTGGTGGCCAACCTGGCACCACGGAAAATGAAATTCGGCATTTCCGAAGGCATGGTGCTGGCCGCCGGCCCCGGCGG
AGATGATATTCATATTCTCAGCCCCGACAGCGGCGCCGAACCCGGCATGGAAGTGCGTTAA

Upstream 100 bases:

>100_bases
AAATGCCCACCGGCGCCCCTGTTCCCAGGGCCCAGGTTTCACCGCGAATATCACAGGATGAAAAACCCCGGCAGCACCCG
TATCATAGGCCACCCATTTT

Downstream 100 bases:

>100_bases
ATAGACGTACGCTAATTGGCGACATAAAAAAACCGGCCACCGCCGGTTTTTTTATGTCTATCTAAAATCAAATCACCGCA
GAATGTTGGGCAGAGTGTCG

Product: methionyl-tRNA synthetase

Products: NA

Alternate protein names: Methionine--tRNA ligase; MetRS

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MEIDAVPMSDTPRKILVTSALPYANGPIHLGHLLEYIQTDIWVRFQKLRGQQCIYVCADDAHGTAIMLKAEENGVTPEQQ
IAQVKADHERDFADFQVNFDNYYSTHSPENRALSEMVFQRNKDAGYILEKTITQLYDPQKGMFLADRFVKGTCPKCKSED
QYGDNCEVCGATYTPAELIEPYSSVSGATPVEKETTQLFFDLPKFEALLREWTRSGALQEQVANKLQEWIEDLQPWDISR
EAPYFGFEIPGYPGKYFYVWLDAPIGYMASFQNYCDREGLSFDDYWGKESTAELYHFIGKDIINFHGLFWPAMLDGAGLR
KPTAIYSHGFVTVNGAKMSKSRGTFIKARTYLDHLSPEYLRYYFAAKLSSRVDDFDLNLEDFAQRVNSDLVGKLVNIASR
TGNFVKKFGGTLSTELDNMMLVREVQEAGPRIADFYEKREFGKAMREIMALADHANVYIADKAPWSLSKEEGKEQEVLAI
CSTAINVFRLLVIYLKPVLPALAERAEAFMQVEPLTWADSEQLLLGHEIAKFKPLLSRVDMAQVESMLEDSKESTPAPAA
AKPKKAATQKADAADNDETISIDDFLKVKLRVARVAKAAHVDGADKLLQLTLDVGELGQRNVFAGIKARYAPEELEGKLV
VLVANLAPRKMKFGISEGMVLAAGPGGDDIHILSPDSGAEPGMEVR

Sequences:

>Translated_686_residues
MEIDAVPMSDTPRKILVTSALPYANGPIHLGHLLEYIQTDIWVRFQKLRGQQCIYVCADDAHGTAIMLKAEENGVTPEQQ
IAQVKADHERDFADFQVNFDNYYSTHSPENRALSEMVFQRNKDAGYILEKTITQLYDPQKGMFLADRFVKGTCPKCKSED
QYGDNCEVCGATYTPAELIEPYSSVSGATPVEKETTQLFFDLPKFEALLREWTRSGALQEQVANKLQEWIEDLQPWDISR
EAPYFGFEIPGYPGKYFYVWLDAPIGYMASFQNYCDREGLSFDDYWGKESTAELYHFIGKDIINFHGLFWPAMLDGAGLR
KPTAIYSHGFVTVNGAKMSKSRGTFIKARTYLDHLSPEYLRYYFAAKLSSRVDDFDLNLEDFAQRVNSDLVGKLVNIASR
TGNFVKKFGGTLSTELDNMMLVREVQEAGPRIADFYEKREFGKAMREIMALADHANVYIADKAPWSLSKEEGKEQEVLAI
CSTAINVFRLLVIYLKPVLPALAERAEAFMQVEPLTWADSEQLLLGHEIAKFKPLLSRVDMAQVESMLEDSKESTPAPAA
AKPKKAATQKADAADNDETISIDDFLKVKLRVARVAKAAHVDGADKLLQLTLDVGELGQRNVFAGIKARYAPEELEGKLV
VLVANLAPRKMKFGISEGMVLAAGPGGDDIHILSPDSGAEPGMEVR
>Mature_686_residues
MEIDAVPMSDTPRKILVTSALPYANGPIHLGHLLEYIQTDIWVRFQKLRGQQCIYVCADDAHGTAIMLKAEENGVTPEQQ
IAQVKADHERDFADFQVNFDNYYSTHSPENRALSEMVFQRNKDAGYILEKTITQLYDPQKGMFLADRFVKGTCPKCKSED
QYGDNCEVCGATYTPAELIEPYSSVSGATPVEKETTQLFFDLPKFEALLREWTRSGALQEQVANKLQEWIEDLQPWDISR
EAPYFGFEIPGYPGKYFYVWLDAPIGYMASFQNYCDREGLSFDDYWGKESTAELYHFIGKDIINFHGLFWPAMLDGAGLR
KPTAIYSHGFVTVNGAKMSKSRGTFIKARTYLDHLSPEYLRYYFAAKLSSRVDDFDLNLEDFAQRVNSDLVGKLVNIASR
TGNFVKKFGGTLSTELDNMMLVREVQEAGPRIADFYEKREFGKAMREIMALADHANVYIADKAPWSLSKEEGKEQEVLAI
CSTAINVFRLLVIYLKPVLPALAERAEAFMQVEPLTWADSEQLLLGHEIAKFKPLLSRVDMAQVESMLEDSKESTPAPAA
AKPKKAATQKADAADNDETISIDDFLKVKLRVARVAKAAHVDGADKLLQLTLDVGELGQRNVFAGIKARYAPEELEGKLV
VLVANLAPRKMKFGISEGMVLAAGPGGDDIHILSPDSGAEPGMEVR

Specific function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation

COG id: COG0143

COG function: function code J; Methionyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Homo sapiens, GI14043022, Length=610, Percent_Identity=29.5081967213115, Blast_Score=275, Evalue=7e-74,
Organism=Homo sapiens, GI24308436, Length=519, Percent_Identity=25.2408477842004, Blast_Score=152, Evalue=1e-36,
Organism=Escherichia coli, GI1788432, Length=684, Percent_Identity=61.8421052631579, Blast_Score=895, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17540794, Length=584, Percent_Identity=28.9383561643836, Blast_Score=234, Evalue=9e-62,
Organism=Caenorhabditis elegans, GI212645096, Length=510, Percent_Identity=26.2745098039216, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71992781, Length=272, Percent_Identity=27.5735294117647, Blast_Score=108, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321704, Length=561, Percent_Identity=29.7682709447415, Blast_Score=249, Evalue=8e-67,
Organism=Saccharomyces cerevisiae, GI6321610, Length=532, Percent_Identity=21.8045112781955, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24655311, Length=563, Percent_Identity=29.1296625222025, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI21358483, Length=516, Percent_Identity=25.7751937984496, Blast_Score=143, Evalue=5e-34,

Paralogues:

None

Copy number: 871 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): SYM_ALCBS (Q0VP51)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693319.1
- ProteinModelPortal:   Q0VP51
- STRING:   Q0VP51
- GeneID:   4211503
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1599
- NMPDR:   fig|393595.12.peg.1603
- eggNOG:   COG0143
- HOGENOM:   HBG721667
- OMA:   CEAVPES
- PhylomeDB:   Q0VP51
- BioCyc:   ABOR393595:ABO_1599-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00098
- InterPro:   IPR001412
- InterPro:   IPR015413
- InterPro:   IPR004495
- InterPro:   IPR014758
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR014729
- InterPro:   IPR002547
- InterPro:   IPR009080
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01041
- TIGRFAMs:   TIGR00398
- TIGRFAMs:   TIGR00399

Pfam domain/function: PF09334 tRNA-synt_1g; PF01588 tRNA_bind; SSF50249 Nucleic_acid_OB; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.10

Molecular weight: Translated: 76793; Mature: 76793

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00178 AA_TRNA_LIGASE_I; PS50886 TRBD

Important sites: BINDING 340-340

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIDAVPMSDTPRKILVTSALPYANGPIHLGHLLEYIQTDIWVRFQKLRGQQCIYVCADD
CCCCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
AHGTAIMLKAEENGVTPEQQIAQVKADHERDFADFQVNFDNYYSTHSPENRALSEMVFQR
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHC
NKDAGYILEKTITQLYDPQKGMFLADRFVKGTCPKCKSEDQYGDNCEVCGATYTPAELIE
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHC
PYSSVSGATPVEKETTQLFFDLPKFEALLREWTRSGALQEQVANKLQEWIEDLQPWDISR
HHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
EAPYFGFEIPGYPGKYFYVWLDAPIGYMASFQNYCDREGLSFDDYWGKESTAELYHFIGK
CCCCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DIINFHGLFWPAMLDGAGLRKPTAIYSHGFVTVNGAKMSKSRGTFIKARTYLDHLSPEYL
HHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEECCEECCCCCCEEEHHHHHHHCCHHHH
RYYFAAKLSSRVDDFDLNLEDFAQRVNSDLVGKLVNIASRTGNFVKKFGGTLSTELDNMM
HHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LVREVQEAGPRIADFYEKREFGKAMREIMALADHANVYIADKAPWSLSKEEGKEQEVLAI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCHHHHHHH
CSTAINVFRLLVIYLKPVLPALAERAEAFMQVEPLTWADSEQLLLGHEIAKFKPLLSRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
MAQVESMLEDSKESTPAPAAAKPKKAATQKADAADNDETISIDDFLKVKLRVARVAKAAH
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHC
VDGADKLLQLTLDVGELGQRNVFAGIKARYAPEELEGKLVVLVANLAPRKMKFGISEGMV
CCCHHHHHHHHHCHHHCCCCCCHHHHHCCCCCHHHCCCEEEEEECCCCCHHCCCCCCCEE
LAAGPGGDDIHILSPDSGAEPGMEVR
EEECCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MEIDAVPMSDTPRKILVTSALPYANGPIHLGHLLEYIQTDIWVRFQKLRGQQCIYVCADD
CCCCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
AHGTAIMLKAEENGVTPEQQIAQVKADHERDFADFQVNFDNYYSTHSPENRALSEMVFQR
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHC
NKDAGYILEKTITQLYDPQKGMFLADRFVKGTCPKCKSEDQYGDNCEVCGATYTPAELIE
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHC
PYSSVSGATPVEKETTQLFFDLPKFEALLREWTRSGALQEQVANKLQEWIEDLQPWDISR
HHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
EAPYFGFEIPGYPGKYFYVWLDAPIGYMASFQNYCDREGLSFDDYWGKESTAELYHFIGK
CCCCCCEECCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
DIINFHGLFWPAMLDGAGLRKPTAIYSHGFVTVNGAKMSKSRGTFIKARTYLDHLSPEYL
HHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEECCEECCCCCCEEEHHHHHHHCCHHHH
RYYFAAKLSSRVDDFDLNLEDFAQRVNSDLVGKLVNIASRTGNFVKKFGGTLSTELDNMM
HHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LVREVQEAGPRIADFYEKREFGKAMREIMALADHANVYIADKAPWSLSKEEGKEQEVLAI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCHHHHHHH
CSTAINVFRLLVIYLKPVLPALAERAEAFMQVEPLTWADSEQLLLGHEIAKFKPLLSRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
MAQVESMLEDSKESTPAPAAAKPKKAATQKADAADNDETISIDDFLKVKLRVARVAKAAH
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHC
VDGADKLLQLTLDVGELGQRNVFAGIKARYAPEELEGKLVVLVANLAPRKMKFGISEGMV
CCCHHHHHHHHHCHHHCCCCCCHHHHHCCCCCHHHCCCEEEEEECCCCCHHCCCCCCCEE
LAAGPGGDDIHILSPDSGAEPGMEVR
EEECCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA