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The map label for this gene is lspA [H]

Identifier: 110834230

GI number: 110834230

Start: 1557835

End: 1558245

Strand: Direct

Name: lspA [H]

Synonym: ABO_1369

Alternate gene names: 110834230

Gene position: 1557835-1558245 (Clockwise)

Preceding gene: 110834229

Following gene: 110834232

Centisome position: 49.93

GC content: 49.39

Gene sequence:

>411_bases
ATGGCCTATGGCGAGTCTATTTCAGTGACCCCGTTCTTTAACTGGGTGCACGTATGGAACACCGGTGCCGCATTCAGTCT
TTTTGCGAATGGCGGAGGCTGGCAGCGCTATTTTTTAATCGGAATCGCGGTGGTGGTCTCGATTTTCCTGATCAAGCTGA
TTCTTGAAAATCGTCATAAAGGAGAAGCCTTCGCTTACAGTCTTATCCTCGGTGGCGCCATGGGCAACCTGATTGACCGA
ATATTTCGCGGCTACGTTGTGGATTCCTTTGATTTCTATTGGCGGGACTGGCACTGGCCGGCCTTTAATCTGGCTGATAT
TGCTATTGTCACCGGTGCCTTGCTTTTCGTTTCCGGCAGTTTGTTGGGCGAAAAAACAAACACCAATACAAACCCAGATA
GGCAAGGCTGA

Upstream 100 bases:

>100_bases
GCTCATTATTGGCAACAAGCACTCGTCGTATGCCCTGTTTTCCATATCGAGCCTGCTGGCAGCGTCAGATCAGGCTGCAA
AGTGGCTGGTGCAGCAATCA

Downstream 100 bases:

>100_bases
CGTTACAGCTATGAACGCCATTGGGAAGAATGTGCGGTTCGCTAAGCGTGGGCTTCTTATCGTGTTTTGCTCAGACCCGG
CAAGCGGGTCATCCTGTAGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MAYGESISVTPFFNWVHVWNTGAAFSLFANGGGWQRYFLIGIAVVVSIFLIKLILENRHKGEAFAYSLILGGAMGNLIDR
IFRGYVVDSFDFYWRDWHWPAFNLADIAIVTGALLFVSGSLLGEKTNTNTNPDRQG

Sequences:

>Translated_136_residues
MAYGESISVTPFFNWVHVWNTGAAFSLFANGGGWQRYFLIGIAVVVSIFLIKLILENRHKGEAFAYSLILGGAMGNLIDR
IFRGYVVDSFDFYWRDWHWPAFNLADIAIVTGALLFVSGSLLGEKTNTNTNPDRQG
>Mature_135_residues
AYGESISVTPFFNWVHVWNTGAAFSLFANGGGWQRYFLIGIAVVVSIFLIKLILENRHKGEAFAYSLILGGAMGNLIDRI
FRGYVVDSFDFYWRDWHWPAFNLADIAIVTGALLFVSGSLLGEKTNTNTNPDRQG

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=130, Percent_Identity=43.8461538461538, Blast_Score=108, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 15214; Mature: 15082

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYGESISVTPFFNWVHVWNTGAAFSLFANGGGWQRYFLIGIAVVVSIFLIKLILENRHK
CCCCCCEEECCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEAFAYSLILGGAMGNLIDRIFRGYVVDSFDFYWRDWHWPAFNLADIAIVTGALLFVSGS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
LLGEKTNTNTNPDRQG
HCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYGESISVTPFFNWVHVWNTGAAFSLFANGGGWQRYFLIGIAVVVSIFLIKLILENRHK
CCCCCEEECCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEAFAYSLILGGAMGNLIDRIFRGYVVDSFDFYWRDWHWPAFNLADIAIVTGALLFVSGS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
LLGEKTNTNTNPDRQG
HCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA