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The map label for this gene is corA [H]

Identifier: 110834196

GI number: 110834196

Start: 1517255

End: 1518145

Strand: Direct

Name: corA [H]

Synonym: ABO_1335

Alternate gene names: 110834196

Gene position: 1517255-1518145 (Clockwise)

Preceding gene: 110834194

Following gene: 110834199

Centisome position: 48.63

GC content: 49.94

Gene sequence:

>891_bases
ATGCCTACCTTATCTGAGGAAGGCAGCTGGATCGACCTAGTAGATGCCGAGGACGCAGAACGCAACCTGGTTCAGCAATT
TCTCCAGACCGAACTACCTGATTCCGACGATATGGAAGAAATTGAAGCTTCCGCCCGTTTTTTCAGTGATGAGCAGGGGC
TTCATGTCCACTCTTTGTTTATGTTCCAATCCGAGGGCCGGGCACGGACCTCCACAGTTGCTTTTATCGTCCAAGAAGGG
CGATTGCTCTCATTCCGAGATTCCCGGTTACCGGATTTCCGCTTATTGCGCCTGCGAGTCCGCCGGGGTTGGGTCAAGGT
ATCCCAGCCTTTGGATATTTTGCTAAGTATACTTGATCAAAAAGTGGAAAATCTTGCGGATGCGCTTGAGGACGTACACC
GAGACTTGGAAAAAGTCGGCTACAGCGTGCTGGAGGAAGAAAACGGAAAACTGGAAGAAGACATTGAGCGTCTGGCCCAG
CTAGAAGACACTAACGGGAAAATCCGTTTGTGTTTGATGGATACCCAGCGCTCTATCTCGTTTATTCAGCGCTATGTGCG
CCCTGATAAAATTCGGCGGAGAACCTGTGCGGAAATTCAGCATGACCTAGATACGTTGATGTCACACACCACCTTCCTGT
TCGACAAAATCAACTTTCTGATGGATGCAGCCCAGGGCTTTATCAACATTCAGCAAAATCAGATCATCAAGATATTCTCT
ATTGCCGCCGTGGTGTTTCTGCCCCCCACCATGATCGCCAGCATCTACGGGATGAACTTCGACATTATGCCAGAACTGGA
CTTCCGCTTTGGCTACCCCATGGCAATTGGTTTGATGGTGTTGTCCGGCATGGCGCCGTATTGGTACTTCAAACGCAAGG
GCTGGTTGTAG

Upstream 100 bases:

>100_bases
TAAACGGCGTATTGCCGGCAAGAATGATCAGGAAAACATCATGCTGCATATTTTTCGTATTGAAGATGGTGTTCTACGAG
AAAAAGAGGTGAATGCCACT

Downstream 100 bases:

>100_bases
AAGGCATCGGTGGTGGGTAGCAGAGGCTCACCCCCCGCACATCAACCGGCCAATACCCATCCGCTCGTTGTCTCAGCCGC
CTTGCCATCCTCGGCCAGCT

Product: Mg2+/Co2+ transporter

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPTLSEEGSWIDLVDAEDAERNLVQQFLQTELPDSDDMEEIEASARFFSDEQGLHVHSLFMFQSEGRARTSTVAFIVQEG
RLLSFRDSRLPDFRLLRLRVRRGWVKVSQPLDILLSILDQKVENLADALEDVHRDLEKVGYSVLEEENGKLEEDIERLAQ
LEDTNGKIRLCLMDTQRSISFIQRYVRPDKIRRRTCAEIQHDLDTLMSHTTFLFDKINFLMDAAQGFINIQQNQIIKIFS
IAAVVFLPPTMIASIYGMNFDIMPELDFRFGYPMAIGLMVLSGMAPYWYFKRKGWL

Sequences:

>Translated_296_residues
MPTLSEEGSWIDLVDAEDAERNLVQQFLQTELPDSDDMEEIEASARFFSDEQGLHVHSLFMFQSEGRARTSTVAFIVQEG
RLLSFRDSRLPDFRLLRLRVRRGWVKVSQPLDILLSILDQKVENLADALEDVHRDLEKVGYSVLEEENGKLEEDIERLAQ
LEDTNGKIRLCLMDTQRSISFIQRYVRPDKIRRRTCAEIQHDLDTLMSHTTFLFDKINFLMDAAQGFINIQQNQIIKIFS
IAAVVFLPPTMIASIYGMNFDIMPELDFRFGYPMAIGLMVLSGMAPYWYFKRKGWL
>Mature_295_residues
PTLSEEGSWIDLVDAEDAERNLVQQFLQTELPDSDDMEEIEASARFFSDEQGLHVHSLFMFQSEGRARTSTVAFIVQEGR
LLSFRDSRLPDFRLLRLRVRRGWVKVSQPLDILLSILDQKVENLADALEDVHRDLEKVGYSVLEEENGKLEEDIERLAQL
EDTNGKIRLCLMDTQRSISFIQRYVRPDKIRRRTCAEIQHDLDTLMSHTTFLFDKINFLMDAAQGFINIQQNQIIKIFSI
AAVVFLPPTMIASIYGMNFDIMPELDFRFGYPMAIGLMVLSGMAPYWYFKRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=289, Percent_Identity=49.8269896193772, Blast_Score=290, Evalue=6e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 34355; Mature: 34224

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLSEEGSWIDLVDAEDAERNLVQQFLQTELPDSDDMEEIEASARFFSDEQGLHVHSLF
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEHEE
MFQSEGRARTSTVAFIVQEGRLLSFRDSRLPDFRLLRLRVRRGWVKVSQPLDILLSILDQ
EECCCCCCHHHHEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KVENLADALEDVHRDLEKVGYSVLEEENGKLEEDIERLAQLEDTNGKIRLCLMDTQRSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
FIQRYVRPDKIRRRTCAEIQHDLDTLMSHTTFLFDKINFLMDAAQGFINIQQNQIIKIFS
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
IAAVVFLPPTMIASIYGMNFDIMPELDFRFGYPMAIGLMVLSGMAPYWYFKRKGWL
HHHHHHCCHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCC
>Mature Secondary Structure 
PTLSEEGSWIDLVDAEDAERNLVQQFLQTELPDSDDMEEIEASARFFSDEQGLHVHSLF
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEHEE
MFQSEGRARTSTVAFIVQEGRLLSFRDSRLPDFRLLRLRVRRGWVKVSQPLDILLSILDQ
EECCCCCCHHHHEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KVENLADALEDVHRDLEKVGYSVLEEENGKLEEDIERLAQLEDTNGKIRLCLMDTQRSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
FIQRYVRPDKIRRRTCAEIQHDLDTLMSHTTFLFDKINFLMDAAQGFINIQQNQIIKIFS
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
IAAVVFLPPTMIASIYGMNFDIMPELDFRFGYPMAIGLMVLSGMAPYWYFKRKGWL
HHHHHHCCHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]