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The map label for this gene is adhA [H]

Identifier: 110834092

GI number: 110834092

Start: 1402134

End: 1403126

Strand: Direct

Name: adhA [H]

Synonym: ABO_1231

Alternate gene names: 110834092

Gene position: 1402134-1403126 (Clockwise)

Preceding gene: 110834091

Following gene: 110834093

Centisome position: 44.94

GC content: 55.39

Gene sequence:

>993_bases
ATGACATTTAAGGCATTACAGACCCGCGAAACCGAGGCCGGTTACAGTAACGTGCTGGTTGACCGCGAGCTAAGTGAGCT
GGGCGAAGGCGGTGTATTGGTACGGGTGCAATGGTCGTCTCTGAATTACAAGGATGCACTGTCAGCCACCGGCAACAAAG
GCGTTACCCGCCAATTCCCTCATACCCCAGGCATTGATGCGGTTGGCGTGGTTGAAGAGGCGAGTGATGGGCCTTTTAGT
GCGGGCGATGCGGTGATTTGCACAGGCTATGATCTGGGGATGAACACGGATGGCGGTTATGCAGAATATATCCGCGTACC
GGCTGAGTGGCTAGTGCCGCTACCAGAAGGCCTTGCGCCTCGCGATGCAATGTTGCTTGGTACGGCAGGGCTAACCGCAG
CCTTGAGTGTTGAATCGTTGCTGGATACGGGCGTTAACCCGGATCAGGGGCCCGTGCTGGTGACTGGCGCGACTGGTGGC
GTGGGCAGCATTAGTGTTGCGATACTGGCTAAGTTAGGTTTTGAGGTGGTGGCCGTTAGTGGCAAAGCAGACGCCCACGA
ATGGCTCACTGAGCTTGGTGCATCACGCATCATTGATCGCAATGATTTTCTGGAAAGTGCCGCCAAGCCCATGGCCAAAG
AGCAGTGGTCGGGCGCTGTGGATTGCGTGGGGGGTGAAATGCTGGCCGCTGCTCTGAAGGGTCTAAAGTACGGAGGTAGT
GCCACTTGCTGTGGGTTAGCCGGTTCTCCCAAGCTTGAGATGACGGTTTTTCCATTCATTTTGCGCGGAGTAAATCTGTT
AGGGGTAGATAGCGTTGAATTACCCTGTGAAATTAAGCAGCAAATGTGGCAGTTACTGGCGGATGAATGGATGCCGAAAG
ACCTTTCACTGCTGGAAGCGGCGCAAACGGAGCTTTCTGGGGTGACCGATTGGGTGGATCGCATTCTGGCTGGAGGAGTT
CGCGGGCGGGTCGTGGTTAAGCTGCCTGAGTAA

Upstream 100 bases:

>100_bases
TAGAAGCAATGGCACATCGGGTGTTGGAAAAGTTTTGGCATCGTGGCAGCCAACGTCAGATTCATTAGTACCTTTACCGA
ACACTGCAAAGGAGTAGCTC

Downstream 100 bases:

>100_bases
TAGCTACAGGGTTTTGAGAGCAGCGCATACAGCACATTGTTTTCTCATCGTCGACAATCATTGTCCTCGTATTCCCTCGA
TGCCCGCTTGATCAAGCGGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTFKALQTRETEAGYSNVLVDRELSELGEGGVLVRVQWSSLNYKDALSATGNKGVTRQFPHTPGIDAVGVVEEASDGPFS
AGDAVICTGYDLGMNTDGGYAEYIRVPAEWLVPLPEGLAPRDAMLLGTAGLTAALSVESLLDTGVNPDQGPVLVTGATGG
VGSISVAILAKLGFEVVAVSGKADAHEWLTELGASRIIDRNDFLESAAKPMAKEQWSGAVDCVGGEMLAAALKGLKYGGS
ATCCGLAGSPKLEMTVFPFILRGVNLLGVDSVELPCEIKQQMWQLLADEWMPKDLSLLEAAQTELSGVTDWVDRILAGGV
RGRVVVKLPE

Sequences:

>Translated_330_residues
MTFKALQTRETEAGYSNVLVDRELSELGEGGVLVRVQWSSLNYKDALSATGNKGVTRQFPHTPGIDAVGVVEEASDGPFS
AGDAVICTGYDLGMNTDGGYAEYIRVPAEWLVPLPEGLAPRDAMLLGTAGLTAALSVESLLDTGVNPDQGPVLVTGATGG
VGSISVAILAKLGFEVVAVSGKADAHEWLTELGASRIIDRNDFLESAAKPMAKEQWSGAVDCVGGEMLAAALKGLKYGGS
ATCCGLAGSPKLEMTVFPFILRGVNLLGVDSVELPCEIKQQMWQLLADEWMPKDLSLLEAAQTELSGVTDWVDRILAGGV
RGRVVVKLPE
>Mature_329_residues
TFKALQTRETEAGYSNVLVDRELSELGEGGVLVRVQWSSLNYKDALSATGNKGVTRQFPHTPGIDAVGVVEEASDGPFSA
GDAVICTGYDLGMNTDGGYAEYIRVPAEWLVPLPEGLAPRDAMLLGTAGLTAALSVESLLDTGVNPDQGPVLVTGATGGV
GSISVAILAKLGFEVVAVSGKADAHEWLTELGASRIIDRNDFLESAAKPMAKEQWSGAVDCVGGEMLAAALKGLKYGGSA
TCCGLAGSPKLEMTVFPFILRGVNLLGVDSVELPCEIKQQMWQLLADEWMPKDLSLLEAAQTELSGVTDWVDRILAGGVR
GRVVVKLPE

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=305, Percent_Identity=22.9508196721311, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI13236495, Length=305, Percent_Identity=22.9508196721311, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789651, Length=305, Percent_Identity=49.1803278688525, Blast_Score=279, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 34666; Mature: 34535

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKALQTRETEAGYSNVLVDRELSELGEGGVLVRVQWSSLNYKDALSATGNKGVTRQFP
CCCCCCCCCCCCCCCHHEEECCHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCC
HTPGIDAVGVVEEASDGPFSAGDAVICTGYDLGMNTDGGYAEYIRVPAEWLVPLPEGLAP
CCCCCCCEEEEECCCCCCCCCCCEEEEECEECCCCCCCCHHHEEECCHHHCCCCCCCCCC
RDAMLLGTAGLTAALSVESLLDTGVNPDQGPVLVTGATGGVGSISVAILAKLGFEVVAVS
CCEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEEC
GKADAHEWLTELGASRIIDRNDFLESAAKPMAKEQWSGAVDCVGGEMLAAALKGLKYGGS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHCCCCEECCCHHHHHHHHHHCCCCCC
ATCCGLAGSPKLEMTVFPFILRGVNLLGVDSVELPCEIKQQMWQLLADEWMPKDLSLLEA
CEEECCCCCCCEEEEHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
AQTELSGVTDWVDRILAGGVRGRVVVKLPE
HHHHHHHHHHHHHHHHHCCCCCEEEEECCC
>Mature Secondary Structure 
TFKALQTRETEAGYSNVLVDRELSELGEGGVLVRVQWSSLNYKDALSATGNKGVTRQFP
CCCCCCCCCCCCCCHHEEECCHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCC
HTPGIDAVGVVEEASDGPFSAGDAVICTGYDLGMNTDGGYAEYIRVPAEWLVPLPEGLAP
CCCCCCCEEEEECCCCCCCCCCCEEEEECEECCCCCCCCHHHEEECCHHHCCCCCCCCCC
RDAMLLGTAGLTAALSVESLLDTGVNPDQGPVLVTGATGGVGSISVAILAKLGFEVVAVS
CCEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEEC
GKADAHEWLTELGASRIIDRNDFLESAAKPMAKEQWSGAVDCVGGEMLAAALKGLKYGGS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHCCCCEECCCHHHHHHHHHHCCCCCC
ATCCGLAGSPKLEMTVFPFILRGVNLLGVDSVELPCEIKQQMWQLLADEWMPKDLSLLEA
CEEECCCCCCCEEEEHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
AQTELSGVTDWVDRILAGGVRGRVVVKLPE
HHHHHHHHHHHHHHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]