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The map label for this gene is fabD [H]

Identifier: 110833929

GI number: 110833929

Start: 1210736

End: 1211665

Strand: Direct

Name: fabD [H]

Synonym: ABO_1068

Alternate gene names: 110833929

Gene position: 1210736-1211665 (Clockwise)

Preceding gene: 110833928

Following gene: 110833930

Centisome position: 38.8

GC content: 56.88

Gene sequence:

>930_bases
ATGTCCAAGACAGCCTTTATTTTTCCTGGCCAAGGGTCTCAGGGCCTGGGGATGCTCAGTGAGTTCGCCGAACGTCCGGC
GGTGAAGCAAACCTTTCAGGAAGCCTCTGGTGCGCTGGATCAGGACCTCTGGGCGTTAGCCCAAGAAGGGCCAAAAGAAG
CGCTCAATCAGACAGAAATCACTCAGCCTTTACTGCTGACCGCAGGCGTTGCCCTGTGGCGTTTGTGGGAACAGAGCGGT
GGCCCACGGCCGAATGTGTTGGCAGGGCATAGCCTGGGTGAGTACACGGCGCTGAGTTGCGCCGGAGTCATTAATCTGGG
TGATGCCGTGCGGCTGGTGCGTACTCGTGGCCAGTTGATGCAGCAGGCCGTTGGCCAGGGTGAAGGCAGCATGGCTGCCA
TTCTCGGGTTGGATGATGATCAGGTTCGCAGCGCTTGTGAGCAGGCAGCTCAGGGCGGCGTTGTTGAGGCTGTCAATTTT
AATGCGCCAGGACAGGTGGTTATTGCCGGTTCAGCGGATGCGGTTGAGCGGGCTATTGCAGCCTGTAAAGAGGCTGGTGC
GAAACGTGCCATGGCGCTTCCGGTCAGTGTGCCGTCCCATTGTGCGTTGATGAAACCTGCCGCTGCACAGCTTGCCGATA
CCTTGAGTGATACCCGTTTTCACGCGGCGGAAATGCCGGTGATCAATAATGTGGATGTGGCCATGGAAACGGATCCGGAG
AAAATTCGTGATGCGTTGATTCGCCAACTTTATTCACCGGTGCGCTGGGTGGAAACCATTCAGGCACTGCAAGAGCAGGG
TGTTGGTCATCTTTATGAGTGTGGCCCGGGCAAGGTTTTGTGTGGTTTGGTGAAACGCATTGACCGGGAATTGGCCGCTC
GTCCGCTGGAAACAGAGGCAGCTTTCACGGCTGCTCTGCAAGGAGAATAA

Upstream 100 bases:

>100_bases
CTGGCCCCGAATGTCTATTCATACTTTGTTTCAGGCCTGACCGGACAGCGAAAGCGAAAGCCGGCATACTGCGGCCTGCC
TATTTTCAAGGGGATGTTGC

Downstream 100 bases:

>100_bases
GCATGTCAGACAAGAAAGTGGCACTGGTAACCGGCGCTAGCCGGGGCATCGGCCGGGCGATTGCCGAACAACTGATTGCG
AATGGTTTTTTTGTGGTTGG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSKTAFIFPGQGSQGLGMLSEFAERPAVKQTFQEASGALDQDLWALAQEGPKEALNQTEITQPLLLTAGVALWRLWEQSG
GPRPNVLAGHSLGEYTALSCAGVINLGDAVRLVRTRGQLMQQAVGQGEGSMAAILGLDDDQVRSACEQAAQGGVVEAVNF
NAPGQVVIAGSADAVERAIAACKEAGAKRAMALPVSVPSHCALMKPAAAQLADTLSDTRFHAAEMPVINNVDVAMETDPE
KIRDALIRQLYSPVRWVETIQALQEQGVGHLYECGPGKVLCGLVKRIDRELAARPLETEAAFTAALQGE

Sequences:

>Translated_309_residues
MSKTAFIFPGQGSQGLGMLSEFAERPAVKQTFQEASGALDQDLWALAQEGPKEALNQTEITQPLLLTAGVALWRLWEQSG
GPRPNVLAGHSLGEYTALSCAGVINLGDAVRLVRTRGQLMQQAVGQGEGSMAAILGLDDDQVRSACEQAAQGGVVEAVNF
NAPGQVVIAGSADAVERAIAACKEAGAKRAMALPVSVPSHCALMKPAAAQLADTLSDTRFHAAEMPVINNVDVAMETDPE
KIRDALIRQLYSPVRWVETIQALQEQGVGHLYECGPGKVLCGLVKRIDRELAARPLETEAAFTAALQGE
>Mature_308_residues
SKTAFIFPGQGSQGLGMLSEFAERPAVKQTFQEASGALDQDLWALAQEGPKEALNQTEITQPLLLTAGVALWRLWEQSGG
PRPNVLAGHSLGEYTALSCAGVINLGDAVRLVRTRGQLMQQAVGQGEGSMAAILGLDDDQVRSACEQAAQGGVVEAVNFN
APGQVVIAGSADAVERAIAACKEAGAKRAMALPVSVPSHCALMKPAAAQLADTLSDTRFHAAEMPVINNVDVAMETDPEK
IRDALIRQLYSPVRWVETIQALQEQGVGHLYECGPGKVLCGLVKRIDRELAARPLETEAAFTAALQGE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=29.7029702970297, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=61.6883116883117, Blast_Score=358, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71984332, Length=292, Percent_Identity=28.7671232876712, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=296, Percent_Identity=29.0540540540541, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=32.013201320132, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32666; Mature: 32534

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAFIFPGQGSQGLGMLSEFAERPAVKQTFQEASGALDQDLWALAQEGPKEALNQTEI
CCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
TQPLLLTAGVALWRLWEQSGGPRPNVLAGHSLGEYTALSCAGVINLGDAVRLVRTRGQLM
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
QQAVGQGEGSMAAILGLDDDQVRSACEQAAQGGVVEAVNFNAPGQVVIAGSADAVERAIA
HHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHHHH
ACKEAGAKRAMALPVSVPSHCALMKPAAAQLADTLSDTRFHAAEMPVINNVDVAMETDPE
HHHHHCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHH
KIRDALIRQLYSPVRWVETIQALQEQGVGHLYECGPGKVLCGLVKRIDRELAARPLETEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
AFTAALQGE
HHHHHCCCC
>Mature Secondary Structure 
SKTAFIFPGQGSQGLGMLSEFAERPAVKQTFQEASGALDQDLWALAQEGPKEALNQTEI
CCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
TQPLLLTAGVALWRLWEQSGGPRPNVLAGHSLGEYTALSCAGVINLGDAVRLVRTRGQLM
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
QQAVGQGEGSMAAILGLDDDQVRSACEQAAQGGVVEAVNFNAPGQVVIAGSADAVERAIA
HHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHHHH
ACKEAGAKRAMALPVSVPSHCALMKPAAAQLADTLSDTRFHAAEMPVINNVDVAMETDPE
HHHHHCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHH
KIRDALIRQLYSPVRWVETIQALQEQGVGHLYECGPGKVLCGLVKRIDRELAARPLETEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
AFTAALQGE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]