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The map label for this gene is kdsB

Identifier: 110833918

GI number: 110833918

Start: 1198991

End: 1199746

Strand: Direct

Name: kdsB

Synonym: ABO_1057

Alternate gene names: 110833918

Gene position: 1198991-1199746 (Clockwise)

Preceding gene: 110833917

Following gene: 110833919

Centisome position: 38.43

GC content: 54.89

Gene sequence:

>756_bases
ATGAGCTTTTACGTAGTTGTGCCGGCACGGTATGCGTCTACCCGTTTGCCGGGCAAGCCGTTGGCGGATATTGCCGGGAA
AACCATGGTGGAGCGGGTGGCGCAGCGCTGCCAGCAAAGTGATGCTGATCAGATTTATGTGGCTACCGACGATCGTCGTA
TTGCCGATGTGCTGGGTGACACCGTGCCCGTGGTTATGACGCGAGAGGATCATCCTTCTGGGACAGATCGTCTTCAAGAG
GTGGCTACAAAACTTGCCTTGGCCGACGACGACATTATCGTCAATGTACAGGGTGACGAGCCGTTAATCCCCCCTGCGGT
GATCAATCAAGTGGCGGCAAACCTGGCGGCGAACCCGGACTGCCAGATGGCGACCCTGTGTGAAGCCATCGAAAATTCTG
ATGACCTATTTAATCCTAATGTGGTGAAAGCCGTCTTCGATAATAGGGGCAAGGCATTATATTTTTCCCGAGCGCCGGTG
CCTTGGCACCGTGATGCCTTTGCCGATGGCCAACAAGATTTGTCGGGTGGGCAGTGGTGGAGGCATATCGGCATTTATGC
ATATCGGGTAGCTTTTTTGCATCAGTATGTGCAATGGCAGCCGGCGACACTGGAGAAGCTGGAGTCTTTGGAGCAGCTCC
GCGCTATGGCCAATGGGGTAGCGATTCATGTGGAGCCTGCCTGTGAAGTGGTTCCTGGCGGTGTGGATACACAGACGGAT
CTTGAACGTTTGCGAGCCCAGCTGGGAGGCCAATAA

Upstream 100 bases:

>100_bases
TGCTCAATCCTTGGGCGAGACCCACGAAGCTTAAGAAACGATAGGCCTTTGCGAGTGTTGTGGCTTAATGCTTGGAGCTT
GTGATAATGACGAGGTTTCA

Downstream 100 bases:

>100_bases
TGAGCGTGTCTGTGTTATTTGTTTGTCTCGGGAATATTTGCCGTTCGCCTACCGCTGAAGTGGTTTTTCGGACGCGAGTG
AAGGCAGCTGGGCTTGAGGA

Product: 3-deoxy-D-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSFYVVVPARYASTRLPGKPLADIAGKTMVERVAQRCQQSDADQIYVATDDRRIADVLGDTVPVVMTREDHPSGTDRLQE
VATKLALADDDIIVNVQGDEPLIPPAVINQVAANLAANPDCQMATLCEAIENSDDLFNPNVVKAVFDNRGKALYFSRAPV
PWHRDAFADGQQDLSGGQWWRHIGIYAYRVAFLHQYVQWQPATLEKLESLEQLRAMANGVAIHVEPACEVVPGGVDTQTD
LERLRAQLGGQ

Sequences:

>Translated_251_residues
MSFYVVVPARYASTRLPGKPLADIAGKTMVERVAQRCQQSDADQIYVATDDRRIADVLGDTVPVVMTREDHPSGTDRLQE
VATKLALADDDIIVNVQGDEPLIPPAVINQVAANLAANPDCQMATLCEAIENSDDLFNPNVVKAVFDNRGKALYFSRAPV
PWHRDAFADGQQDLSGGQWWRHIGIYAYRVAFLHQYVQWQPATLEKLESLEQLRAMANGVAIHVEPACEVVPGGVDTQTD
LERLRAQLGGQ
>Mature_250_residues
SFYVVVPARYASTRLPGKPLADIAGKTMVERVAQRCQQSDADQIYVATDDRRIADVLGDTVPVVMTREDHPSGTDRLQEV
ATKLALADDDIIVNVQGDEPLIPPAVINQVAANLAANPDCQMATLCEAIENSDDLFNPNVVKAVFDNRGKALYFSRAPVP
WHRDAFADGQQDLSGGQWWRHIGIYAYRVAFLHQYVQWQPATLEKLESLEQLRAMANGVAIHVEPACEVVPGGVDTQTDL
ERLRAQLGGQ

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=249, Percent_Identity=55.0200803212851, Blast_Score=260, Evalue=8e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_ALCBS (Q0VQP3)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692777.1
- ProteinModelPortal:   Q0VQP3
- SMR:   Q0VQP3
- STRING:   Q0VQP3
- GeneID:   4211215
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1057
- NMPDR:   fig|393595.12.peg.1065
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- PhylomeDB:   Q0VQP3
- BioCyc:   ABOR393595:ABO_1057-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27635; Mature: 27504

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFYVVVPARYASTRLPGKPLADIAGKTMVERVAQRCQQSDADQIYVATDDRRIADVLGD
CEEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCC
TVPVVMTREDHPSGTDRLQEVATKLALADDDIIVNVQGDEPLIPPAVINQVAANLAANPD
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCC
CQMATLCEAIENSDDLFNPNVVKAVFDNRGKALYFSRAPVPWHRDAFADGQQDLSGGQWW
CHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHCCCHHHCCCHHHH
RHIGIYAYRVAFLHQYVQWQPATLEKLESLEQLRAMANGVAIHVEPACEVVPGGVDTQTD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEECCCCCCCHHH
LERLRAQLGGQ
HHHHHHHHCCC
>Mature Secondary Structure 
SFYVVVPARYASTRLPGKPLADIAGKTMVERVAQRCQQSDADQIYVATDDRRIADVLGD
EEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCC
TVPVVMTREDHPSGTDRLQEVATKLALADDDIIVNVQGDEPLIPPAVINQVAANLAANPD
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCC
CQMATLCEAIENSDDLFNPNVVKAVFDNRGKALYFSRAPVPWHRDAFADGQQDLSGGQWW
CHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHCCCHHHCCCHHHH
RHIGIYAYRVAFLHQYVQWQPATLEKLESLEQLRAMANGVAIHVEPACEVVPGGVDTQTD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEECCCCCCCHHH
LERLRAQLGGQ
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA