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The map label for this gene is lolC [H]

Identifier: 110833910

GI number: 110833910

Start: 1189971

End: 1191215

Strand: Direct

Name: lolC [H]

Synonym: ABO_1049

Alternate gene names: 110833910

Gene position: 1189971-1191215 (Clockwise)

Preceding gene: 110833906

Following gene: 110833911

Centisome position: 38.14

GC content: 53.9

Gene sequence:

>1245_bases
ATGCGCTGCATGTTTCGACCTCTATCTTTCTATGTGGGGCTGCGCTATACCGGCGCCCGTGCCCGCAACAGTTTTATTTC
GGTGATTACACTGATTTCGGCACTAGGCCTGATGTTGGGCGTAGCGGTGCTGATAACGGTGCTTTCAGTCATGAATGGCT
TTGATCGTGAGTTGCAGACCCGCATTTTGGGCATGGTGACGCATCTGTCCGTGCATGGCCGCGAGCCAGTACAGGATTGG
CAGGCGTTGGCCAACCGGTTGGATCACCACGACCAGATTGAAGCGGTCGCGCCGTTTGTGCAGCTTGAAGGCATGCTAAC
TCACCGTGGCAATGTGGCCGGAGCGTTAATTAACGGGATTGACCCGGAGGCCGAGCGAAAGGTGTCCATCGTTGGTGACT
TTATGCACCAAGGCGAGCTGGATAGCTTAGAGTCAGGTGAATTCGATGTGGTACTGGGCTATGGCTTGGCACGGCGGTTG
GATGCGCAGTTGGGGGACAAGATAACCCTGGTGCTGCCGGAGGCCACCATTTCACCCGCAGGGGTGATGCCCCGATTTAA
GCGCTTTACCGTTACCGGTATTTTCCGGGTGCGGGCGGAAGTGGATTCCCTGTATGCCTATGTGAATGTGGCGGATGCGG
CCAAGCTGGCCCGTCAGGCGGGCACGGTGCAGGGCGTGCGGTTGAAACTGAATGATCTGTTCAGTGCATCGAATCTGGGT
TGGACGCTACAGCAGGAACTGGGGCCGAATTATTACACTAGTGACTGGACGAGAAGCCACGGTAACCTTTTCCAAGCCAT
CAAGATGGAAAAAACCATGATGACGCTATTGCTTAGTTTTATTGTGGCGGTGGCGGCCTTCAACATCATATCCAGCCAGG
TCATGTTGGTAACCGAGAAACGCGGCAATATTGCGGTATTGCGTACGTTGGGAGCCTCACCGGGCACCATCATGCGTATT
TTCATGGTGCAAGGTACCTTGATTGGTGTGGCCGGGACGTTGTTAGGTACGGTGCTGGGTGTGTTGCTGGCCACCAATGT
GAGCAATATTGCCGAGTGGGTGGAAAAAACCTTTAACACTCGTTTATTTGATGCCTATTTTGTGAATTATCTGCCGTCCG
AGCTGCAGTGGTCTGATGTGGGCACTATTGTAAGTATCGCATTGTTTATCAGCTTTTCGGCCACCCTTTATCCTTCCTGG
CGTGCCAGCCGGGTGCAACCGGCAGAGGCGTTGCGCTATGAATAA

Upstream 100 bases:

>100_bases
AACCATTTTGCTAGCTGGTGAACGCTGACACCGATCACAAAGCGGCGTGCCGAGGCGTTTGTGCCAGTGGGCGTAGTATT
TGCCTCGGGTTTCGGGTTAA

Downstream 100 bases:

>100_bases
TTCAACGCCTGTTCTGCAAGCAAAGAAGCTGGTCAAGGCTTATGAAGAGGGTGACAACGAGCTGGAAGTATTGCGCGGTG
TGGAGTTGACCGTAAATAAA

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRCMFRPLSFYVGLRYTGARARNSFISVITLISALGLMLGVAVLITVLSVMNGFDRELQTRILGMVTHLSVHGREPVQDW
QALANRLDHHDQIEAVAPFVQLEGMLTHRGNVAGALINGIDPEAERKVSIVGDFMHQGELDSLESGEFDVVLGYGLARRL
DAQLGDKITLVLPEATISPAGVMPRFKRFTVTGIFRVRAEVDSLYAYVNVADAAKLARQAGTVQGVRLKLNDLFSASNLG
WTLQQELGPNYYTSDWTRSHGNLFQAIKMEKTMMTLLLSFIVAVAAFNIISSQVMLVTEKRGNIAVLRTLGASPGTIMRI
FMVQGTLIGVAGTLLGTVLGVLLATNVSNIAEWVEKTFNTRLFDAYFVNYLPSELQWSDVGTIVSIALFISFSATLYPSW
RASRVQPAEALRYE

Sequences:

>Translated_414_residues
MRCMFRPLSFYVGLRYTGARARNSFISVITLISALGLMLGVAVLITVLSVMNGFDRELQTRILGMVTHLSVHGREPVQDW
QALANRLDHHDQIEAVAPFVQLEGMLTHRGNVAGALINGIDPEAERKVSIVGDFMHQGELDSLESGEFDVVLGYGLARRL
DAQLGDKITLVLPEATISPAGVMPRFKRFTVTGIFRVRAEVDSLYAYVNVADAAKLARQAGTVQGVRLKLNDLFSASNLG
WTLQQELGPNYYTSDWTRSHGNLFQAIKMEKTMMTLLLSFIVAVAAFNIISSQVMLVTEKRGNIAVLRTLGASPGTIMRI
FMVQGTLIGVAGTLLGTVLGVLLATNVSNIAEWVEKTFNTRLFDAYFVNYLPSELQWSDVGTIVSIALFISFSATLYPSW
RASRVQPAEALRYE
>Mature_414_residues
MRCMFRPLSFYVGLRYTGARARNSFISVITLISALGLMLGVAVLITVLSVMNGFDRELQTRILGMVTHLSVHGREPVQDW
QALANRLDHHDQIEAVAPFVQLEGMLTHRGNVAGALINGIDPEAERKVSIVGDFMHQGELDSLESGEFDVVLGYGLARRL
DAQLGDKITLVLPEATISPAGVMPRFKRFTVTGIFRVRAEVDSLYAYVNVADAAKLARQAGTVQGVRLKLNDLFSASNLG
WTLQQELGPNYYTSDWTRSHGNLFQAIKMEKTMMTLLLSFIVAVAAFNIISSQVMLVTEKRGNIAVLRTLGASPGTIMRI
FMVQGTLIGVAGTLLGTVLGVLLATNVSNIAEWVEKTFNTRLFDAYFVNYLPSELQWSDVGTIVSIALFISFSATLYPSW
RASRVQPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=411, Percent_Identity=34.7931873479319, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1787360, Length=416, Percent_Identity=39.9038461538462, Blast_Score=246, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45598; Mature: 45598

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCMFRPLSFYVGLRYTGARARNSFISVITLISALGLMLGVAVLITVLSVMNGFDRELQT
CCCCCCHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RILGMVTHLSVHGREPVQDWQALANRLDHHDQIEAVAPFVQLEGMLTHRGNVAGALINGI
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
DPEAERKVSIVGDFMHQGELDSLESGEFDVVLGYGLARRLDAQLGDKITLVLPEATISPA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCC
GVMPRFKRFTVTGIFRVRAEVDSLYAYVNVADAAKLARQAGTVQGVRLKLNDLFSASNLG
CCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCC
WTLQQELGPNYYTSDWTRSHGNLFQAIKMEKTMMTLLLSFIVAVAAFNIISSQVMLVTEK
EEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEC
RGNIAVLRTLGASPGTIMRIFMVQGTLIGVAGTLLGTVLGVLLATNVSNIAEWVEKTFNT
CCCEEEEEECCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
RLFDAYFVNYLPSELQWSDVGTIVSIALFISFSATLYPSWRASRVQPAEALRYE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MRCMFRPLSFYVGLRYTGARARNSFISVITLISALGLMLGVAVLITVLSVMNGFDRELQT
CCCCCCHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RILGMVTHLSVHGREPVQDWQALANRLDHHDQIEAVAPFVQLEGMLTHRGNVAGALINGI
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
DPEAERKVSIVGDFMHQGELDSLESGEFDVVLGYGLARRLDAQLGDKITLVLPEATISPA
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCC
GVMPRFKRFTVTGIFRVRAEVDSLYAYVNVADAAKLARQAGTVQGVRLKLNDLFSASNLG
CCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCC
WTLQQELGPNYYTSDWTRSHGNLFQAIKMEKTMMTLLLSFIVAVAAFNIISSQVMLVTEK
EEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEC
RGNIAVLRTLGASPGTIMRIFMVQGTLIGVAGTLLGTVLGVLLATNVSNIAEWVEKTFNT
CCCEEEEEECCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
RLFDAYFVNYLPSELQWSDVGTIVSIALFISFSATLYPSWRASRVQPAEALRYE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]