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The map label for this gene is apbE [H]

Identifier: 110833899

GI number: 110833899

Start: 1179049

End: 1180062

Strand: Direct

Name: apbE [H]

Synonym: ABO_1038

Alternate gene names: 110833899

Gene position: 1179049-1180062 (Clockwise)

Preceding gene: 110833898

Following gene: 110833900

Centisome position: 37.79

GC content: 52.17

Gene sequence:

>1014_bases
ATGCTCCGCATCCTCTCTGTACTGGCTTTCTCTCTGCTTCTGCTTTTTGGTGGCTGTGATGACAGCAAGAATCGCCTTTC
TGTGCTCAGTGGCCCGACTATGGGTACCACTTGGAGTGTGAAATATACAGGGACACCGAGTGATGGCGGAGTACAAGCAT
TAAAGGCGGATATTGTAGCGGCGTTGGAGCAAGTAAATGCGCAGATGAGCACTTACCGTCCTGACTCCAATATTAGCCGT
TTTAATCATGCTGAGCCCGGTGCCCTGATGGTGTTGCCATCTGATCTGGTGAAGGTTTTGCATGCCGCTTTTTTGCTTTC
GGAGCAGACTGATGGGGCCTACGACGTGACTGTGGGTCCATTGGTTAATTTGTGGGGCTTTGGGCCTGATCCGGAGCGCT
TTGAGCCTCCGAAACACTCTGAAGTGGAGGCCGCGCTAACACGAGTTGGTTGGCAAAAGCTTATGCTCAGCGAGCAGCAG
TTACTTCAGCCTGGCGGCGTGTATGTGGATCTGTCCTCTATTGCGAAGGGGTATGCGGTGGATAAGGTGGCGGATTTACT
GGACCGTTATGGCTTGAGCAACTATTTAGTAGAAGTGGGGGGTGAATTGCGGGGCAAAGGCAGCAAGCCCTATAAGCAGC
CTTGGCGAGTTGCCGTTGAGCGGCCGATTGCTGGCGTTCGTGAGGTTGAGCAGGTGGTAGACTTGAAGGACATGGCGGTG
GCTACCAGTGGTGATTACCGTAACTTCTTCGAGTCGCAAGGACGATTATTCTCCCATACGATTGATCCACGTACGGGCTA
TCCGGTGCAGCACAAGCTTGCTTCGGTGTCTGTTTTGCACAAAAGTGCAATGATTGCGGATGGGCTGGCCACGGCAATGA
CGGTGCTGGGGCCGGATGAAGGAATGGCTTTTGCCAAAGACCATGAACTGGCCGTATTTTTTATTGTCAGAACTGAGAAG
GGAGTGAAAGAGTTATCGACTCCTGCGTTTGATGCAATTGTGGAGGGTAAGTGA

Upstream 100 bases:

>100_bases
CTTGCCGTTGATCGCGAGCGAAGCTTTACAGAACATGGGCTCCTTTTCTGTGTTCCAGCTTGATCCTTGTTCCTTTGCTT
TATACCTTCGGACCTAAGCA

Downstream 100 bases:

>100_bases
CATGTTCATGACTATTGTGGCGGCAGTAATTTTTATTGGCCTGCTTTTCGCCGGCATGGCTGTGGGCGTGATTCTCTCCA
ACAAGCCGGTAAAGGGATCC

Product: thiamine biosynthesis lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLRILSVLAFSLLLLFGGCDDSKNRLSVLSGPTMGTTWSVKYTGTPSDGGVQALKADIVAALEQVNAQMSTYRPDSNISR
FNHAEPGALMVLPSDLVKVLHAAFLLSEQTDGAYDVTVGPLVNLWGFGPDPERFEPPKHSEVEAALTRVGWQKLMLSEQQ
LLQPGGVYVDLSSIAKGYAVDKVADLLDRYGLSNYLVEVGGELRGKGSKPYKQPWRVAVERPIAGVREVEQVVDLKDMAV
ATSGDYRNFFESQGRLFSHTIDPRTGYPVQHKLASVSVLHKSAMIADGLATAMTVLGPDEGMAFAKDHELAVFFIVRTEK
GVKELSTPAFDAIVEGK

Sequences:

>Translated_337_residues
MLRILSVLAFSLLLLFGGCDDSKNRLSVLSGPTMGTTWSVKYTGTPSDGGVQALKADIVAALEQVNAQMSTYRPDSNISR
FNHAEPGALMVLPSDLVKVLHAAFLLSEQTDGAYDVTVGPLVNLWGFGPDPERFEPPKHSEVEAALTRVGWQKLMLSEQQ
LLQPGGVYVDLSSIAKGYAVDKVADLLDRYGLSNYLVEVGGELRGKGSKPYKQPWRVAVERPIAGVREVEQVVDLKDMAV
ATSGDYRNFFESQGRLFSHTIDPRTGYPVQHKLASVSVLHKSAMIADGLATAMTVLGPDEGMAFAKDHELAVFFIVRTEK
GVKELSTPAFDAIVEGK
>Mature_337_residues
MLRILSVLAFSLLLLFGGCDDSKNRLSVLSGPTMGTTWSVKYTGTPSDGGVQALKADIVAALEQVNAQMSTYRPDSNISR
FNHAEPGALMVLPSDLVKVLHAAFLLSEQTDGAYDVTVGPLVNLWGFGPDPERFEPPKHSEVEAALTRVGWQKLMLSEQQ
LLQPGGVYVDLSSIAKGYAVDKVADLLDRYGLSNYLVEVGGELRGKGSKPYKQPWRVAVERPIAGVREVEQVVDLKDMAV
ATSGDYRNFFESQGRLFSHTIDPRTGYPVQHKLASVSVLHKSAMIADGLATAMTVLGPDEGMAFAKDHELAVFFIVRTEK
GVKELSTPAFDAIVEGK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=333, Percent_Identity=36.3363363363363, Blast_Score=227, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 36583; Mature: 36583

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRILSVLAFSLLLLFGGCDDSKNRLSVLSGPTMGTTWSVKYTGTPSDGGVQALKADIVA
CHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHH
ALEQVNAQMSTYRPDSNISRFNHAEPGALMVLPSDLVKVLHAAFLLSEQTDGAYDVTVGP
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEHHH
LVNLWGFGPDPERFEPPKHSEVEAALTRVGWQKLMLSEQQLLQPGGVYVDLSSIAKGYAV
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEHHHHHCCHHH
DKVADLLDRYGLSNYLVEVGGELRGKGSKPYKQPWRVAVERPIAGVREVEQVVDLKDMAV
HHHHHHHHHHCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHE
ATSGDYRNFFESQGRLFSHTIDPRTGYPVQHKLASVSVLHKSAMIADGLATAMTVLGPDE
ECCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GMAFAKDHELAVFFIVRTEKGVKELSTPAFDAIVEGK
CCEEECCCCEEEEEEEECCCCHHHHCCCHHHHEECCC
>Mature Secondary Structure
MLRILSVLAFSLLLLFGGCDDSKNRLSVLSGPTMGTTWSVKYTGTPSDGGVQALKADIVA
CHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHH
ALEQVNAQMSTYRPDSNISRFNHAEPGALMVLPSDLVKVLHAAFLLSEQTDGAYDVTVGP
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEHHH
LVNLWGFGPDPERFEPPKHSEVEAALTRVGWQKLMLSEQQLLQPGGVYVDLSSIAKGYAV
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEHHHHHCCHHH
DKVADLLDRYGLSNYLVEVGGELRGKGSKPYKQPWRVAVERPIAGVREVEQVVDLKDMAV
HHHHHHHHHHCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHE
ATSGDYRNFFESQGRLFSHTIDPRTGYPVQHKLASVSVLHKSAMIADGLATAMTVLGPDE
ECCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GMAFAKDHELAVFFIVRTEKGVKELSTPAFDAIVEGK
CCEEECCCCEEEEEEEECCCCHHHHCCCHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]