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The map label for this gene is ugd1 [H]

Identifier: 110833793

GI number: 110833793

Start: 1044440

End: 1045606

Strand: Direct

Name: ugd1 [H]

Synonym: ABO_0932

Alternate gene names: 110833793

Gene position: 1044440-1045606 (Clockwise)

Preceding gene: 110833792

Following gene: 110833794

Centisome position: 33.47

GC content: 46.7

Gene sequence:

>1167_bases
ATGAAAATTGCAGTGGCGGGAATGGGGTATGTCGGGTTATCCAATGCGGTGTTGCTGGCCCAGAATAACACCGTAGTGGC
GCTAGATATTGATGCCATAAAGGTAGAGAAAGTTCAAAACGGAATTTCCCCGATTGAGGATGCTGAAATTCAGTGCTTTC
TGACAGCGCAATCGCTGGATTTGCACGCGACAACCGATAAAAATATGGCATTTGAAGGTGCCGATTTTGTAGTAGTGGCG
ACTCCCACTGACTATGACGTAAAGGCAAATTATTTCAATACGAGTAGTGTCGAGCTGGTAATTAGTGATGTGCTGGCTAT
TAATCCCCGCGCTACCATAATAATTAAATCGACGGTGCCGGTGGGTTATACGAAGACGCTGAGGGAACGTTTTGGTGTTG
AAAATATCATCTTTTCTCCGGAGTTTTTGCGGGAAGGCAAAGCCCTGCATGATAATTTGCACCCCTCTCGAATCATTGTA
GGGGCCCAGTGTGAAGCCGCTCGTATTTTTGCTGACTTGCTTGTTCAGGGGGCGGAAACCGTTGCTCCTCCTGTGATATT
GACAGATTCAACCGAGGCAGAAGCGATTAAACTTTTTTCCAATACTTATTTGGCTATGCGGGTGGCCTATTTCAATGAGC
TGGATAGCTATGCCGCTACCCATAACTTGAATACCCGTCAGATCATTGATGGGGTTTGCCTTGATCCGCGGATTGGGGGG
CATTACAACAATCCTTCTTTTGGTTATGGGGGGTATTGTTTGCCCAAAGATACCAAGCAGTTAGTGGCTAACTACGAGGA
TGTGCCGAATAACTTGATTAAGGCCATTGTGGATGCCAACCGGACACGTAAAGATTTTATAGCCGAAGATATTTTACGCC
GTAACCCCGCCCGTGTGGGTATCTACCGGTTGGTGATGAAAGCGGGGTCGGACAACTTTAGGGCCTCTTCCATCCAAGGT
GTTATGAAGCGGCTGAAGGCGAAAGGTATTGAAGTCGTGGTTTACGAGCCGGCACTGGCGGAGGAGGCATTTTTCAATTC
GGTGGTGATTCGCGATTTTGAAACGTTTATTCAAACCTGTGATGTGATTGTTTCTAATCGTATGGTGAGTGAACTGGAAG
GGGTGGCTGACAAGGTTTACACCCGTGATCTTTTTGGAAATGATTAA

Upstream 100 bases:

>100_bases
TTGAGTTTTTGCGCGGCCAGAATATTTAGCTTAAGCGTTATTTTGTTTTGATGGATGGACGATACGGAAGCTTTTCAGCT
GTTTGGGATTGAGGAAATTA

Downstream 100 bases:

>100_bases
TCTTGGAATGCCATGCAGCGTAAAAAGCGGTCTCTTTTATTTCTTATTTTCAGTGTGACGATTTTTATTTTGGGTGCATT
ACTGCCAGGAGAATTAAGGG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIAVAGMGYVGLSNAVLLAQNNTVVALDIDAIKVEKVQNGISPIEDAEIQCFLTAQSLDLHATTDKNMAFEGADFVVVA
TPTDYDVKANYFNTSSVELVISDVLAINPRATIIIKSTVPVGYTKTLRERFGVENIIFSPEFLREGKALHDNLHPSRIIV
GAQCEAARIFADLLVQGAETVAPPVILTDSTEAEAIKLFSNTYLAMRVAYFNELDSYAATHNLNTRQIIDGVCLDPRIGG
HYNNPSFGYGGYCLPKDTKQLVANYEDVPNNLIKAIVDANRTRKDFIAEDILRRNPARVGIYRLVMKAGSDNFRASSIQG
VMKRLKAKGIEVVVYEPALAEEAFFNSVVIRDFETFIQTCDVIVSNRMVSELEGVADKVYTRDLFGND

Sequences:

>Translated_388_residues
MKIAVAGMGYVGLSNAVLLAQNNTVVALDIDAIKVEKVQNGISPIEDAEIQCFLTAQSLDLHATTDKNMAFEGADFVVVA
TPTDYDVKANYFNTSSVELVISDVLAINPRATIIIKSTVPVGYTKTLRERFGVENIIFSPEFLREGKALHDNLHPSRIIV
GAQCEAARIFADLLVQGAETVAPPVILTDSTEAEAIKLFSNTYLAMRVAYFNELDSYAATHNLNTRQIIDGVCLDPRIGG
HYNNPSFGYGGYCLPKDTKQLVANYEDVPNNLIKAIVDANRTRKDFIAEDILRRNPARVGIYRLVMKAGSDNFRASSIQG
VMKRLKAKGIEVVVYEPALAEEAFFNSVVIRDFETFIQTCDVIVSNRMVSELEGVADKVYTRDLFGND
>Mature_388_residues
MKIAVAGMGYVGLSNAVLLAQNNTVVALDIDAIKVEKVQNGISPIEDAEIQCFLTAQSLDLHATTDKNMAFEGADFVVVA
TPTDYDVKANYFNTSSVELVISDVLAINPRATIIIKSTVPVGYTKTLRERFGVENIIFSPEFLREGKALHDNLHPSRIIV
GAQCEAARIFADLLVQGAETVAPPVILTDSTEAEAIKLFSNTYLAMRVAYFNELDSYAATHNLNTRQIIDGVCLDPRIGG
HYNNPSFGYGGYCLPKDTKQLVANYEDVPNNLIKAIVDANRTRKDFIAEDILRRNPARVGIYRLVMKAGSDNFRASSIQG
VMKRLKAKGIEVVVYEPALAEEAFFNSVVIRDFETFIQTCDVIVSNRMVSELEGVADKVYTRDLFGND

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=369, Percent_Identity=24.6612466124661, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI296040438, Length=246, Percent_Identity=26.4227642276423, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI296040443, Length=220, Percent_Identity=25.9090909090909, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=68.5567010309278, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI48994968, Length=399, Percent_Identity=23.3082706766917, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560350, Length=380, Percent_Identity=26.0526315789474, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17136908, Length=378, Percent_Identity=24.3386243386243, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 42704; Mature: 42704

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVAGMGYVGLSNAVLLAQNNTVVALDIDAIKVEKVQNGISPIEDAEIQCFLTAQSLD
CEEEEEECCEECCCCEEEEEECCEEEEEECCCEEHHHHHCCCCCCCCCCEEEEEEEECCE
LHATTDKNMAFEGADFVVVATPTDYDVKANYFNTSSVELVISDVLAINPRATIIIKSTVP
EEEECCCCCEECCCCEEEEECCCCCCEEECEECCCHHHHEEEHHHEECCCEEEEEEECCC
VGYTKTLRERFGVENIIFSPEFLREGKALHDNLHPSRIIVGAQCEAARIFADLLVQGAET
CCHHHHHHHHCCCCCEEECHHHHHCCCHHHCCCCCCEEEEECCCHHHHHHHHHHHCCHHH
VAPPVILTDSTEAEAIKLFSNTYLAMRVAYFNELDSYAATHNLNTRQIIDGVCLDPRIGG
HCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEECCCCCC
HYNNPSFGYGGYCLPKDTKQLVANYEDVPNNLIKAIVDANRTRKDFIAEDILRRNPARVG
CCCCCCCCCCCEECCCHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
IYRLVMKAGSDNFRASSIQGVMKRLKAKGIEVVVYEPALAEEAFFNSVVIRDFETFIQTC
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
DVIVSNRMVSELEGVADKVYTRDLFGND
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIAVAGMGYVGLSNAVLLAQNNTVVALDIDAIKVEKVQNGISPIEDAEIQCFLTAQSLD
CEEEEEECCEECCCCEEEEEECCEEEEEECCCEEHHHHHCCCCCCCCCCEEEEEEEECCE
LHATTDKNMAFEGADFVVVATPTDYDVKANYFNTSSVELVISDVLAINPRATIIIKSTVP
EEEECCCCCEECCCCEEEEECCCCCCEEECEECCCHHHHEEEHHHEECCCEEEEEEECCC
VGYTKTLRERFGVENIIFSPEFLREGKALHDNLHPSRIIVGAQCEAARIFADLLVQGAET
CCHHHHHHHHCCCCCEEECHHHHHCCCHHHCCCCCCEEEEECCCHHHHHHHHHHHCCHHH
VAPPVILTDSTEAEAIKLFSNTYLAMRVAYFNELDSYAATHNLNTRQIIDGVCLDPRIGG
HCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEECCCCCC
HYNNPSFGYGGYCLPKDTKQLVANYEDVPNNLIKAIVDANRTRKDFIAEDILRRNPARVG
CCCCCCCCCCCEECCCHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
IYRLVMKAGSDNFRASSIQGVMKRLKAKGIEVVVYEPALAEEAFFNSVVIRDFETFIQTC
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
DVIVSNRMVSELEGVADKVYTRDLFGND
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]